Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
01/2001
01/16/2001US6174872 Immunotherapy of allergic asthma in both its early and late stages by administering to the mucosa a polynucleotide encoding an asthma-initiating antigen and immunostimulatory neucleotide seqence stimulating the th1 lymhocytes
01/16/2001US6174871 Gene therapies for enhancing cardiac function
01/16/2001US6174869 Method for enhancing neurone survival and agents useful for same
01/16/2001US6174868 Compositions and methods for treatment of hepatitis C virus-associated diseases
01/16/2001US6174860 Nucleic acid isolated from a nematode symbiotic bacterium
01/16/2001US6174726 Method for the immortalization of cells using conditionally transformed helper cells
01/16/2001US6174725 Plant or seed having a dna sequence encoding a high molecular weight glutenin subunit having from 10 to 150 repeats of defined sequence operably linked to a promoter; for bread and noodles
01/16/2001US6174724 Chimeric genes suitable for expression in plant cells
01/16/2001US6174723 Cocaine derivative, protein conjugate thereof, monoclonal antibody producing cell line, method for preparing the cell line and monoclonal antibody
01/16/2001US6174722 Drug screening by using dna template of target sequence under control of regulatory sequence, mixing with nuclear extract and labeled nucleotide, mixing with candidate, binding labeled transcript to solid matrix, and measuring amount
01/16/2001US6174721 Protein having kunitz-type domains of tissue factor pathway inhibitors and lacking glycosylation sites; for prevention and treatment of septic shock
01/16/2001US6174717 Elicitor of the hypersensitive response in plants
01/16/2001US6174715 Polynucleotide coding for micrococcus polypeptide of defined amino acid sequence; for recombinant production; chemical intermediates for vitamin k and ubiquinones
01/16/2001US6174714 Lyss
01/16/2001US6174709 Accumulation of nucleotide sequences; forming a mixture of sample and preferential oligonucleotides, accumulating target nucleotide sequences by polymerase chain reaction
01/16/2001US6174708 Preparation of a multicombinatorial library of antibody gene expression vectors
01/16/2001US6174706 Purified and isolated nucleic acid molecule having a nucleotide sequence encoding the triol polyketide synthase of aspergillus terreus
01/16/2001US6174705 Polypeptides and dna (rna) encoding such polypeptides by recombinant techniques; for the treatment of infection, particularly fungal infections
01/16/2001US6174700 Purification of a polypeptide compound having a polysaccharide binding domain by affinity phase separation
01/16/2001US6174694 Phosphorylation of serine containing substrate; incubate substrate with adenosine triphosphate and a enzymatic protein, monitor the amount of phosphorylation
01/16/2001US6174692 Detecting preferential antigen in sample; incubating monoclonal antibody with sample containing preferential antigen and detecting biinding
01/16/2001US6174691 Deactivating a preferential tumor glycoprotein or a cell expressing preferential glycoprotein; exposing preferential glycoprotein or cell expressing the preferential glycoprotein to a toxic substance
01/16/2001US6174685 Human herpesvirus type 6 protein p100, the corresponding DNA sequences, their preparation and use
01/16/2001US6174683 Immobilization of biomolecular probes by using derivatized polyurethane-based hydrogels; stability, genetic engineering
01/16/2001US6174681 Method and probe set for detecting cancer
01/16/2001US6174676 Cytokine-stress- and oncoprotein-activated human protein kinase kinases
01/16/2001US6174674 Detecting nucleotide sequence adjustment; hybridizing centromeric probe to human sample, hybridizing second teleomeric probe to human sample, detecting centromeric and telomeric hybridization positioning
01/16/2001US6174673 High throughput screening for novel enzymes
01/16/2001US6174670 Achieved with rapid thermal cycling and use of double stranded dna dyes or specific hybridization probes
01/16/2001US6174669 Making full-length cdna libraries utilizing method of labeling of the 5' cap site
01/16/2001US6174666 Reducing adjustments in ribonucleic acid sequences; providing gene coding transcription products, detect regulatory sequences, insert point mutations, transfect mutated gene into cells, culture cells and monitoring gene expression
01/16/2001US6174550 Antifreeze polypeptide-expressing microorganisms useful in fermentation and frozen storage of foods
01/16/2001US6174532 L2 immunogenic peptides of papillomavirus
01/16/2001US6174527 Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
01/16/2001US6174441 Liquid chromatography system and method, such as matched ion polynucleotide chromatography or slalom chromatography, which enhances the separation of polynucleotides such as dsdna
01/16/2001CA2204355C Peripheral nervous system specific sodium channels, dna encoding therefor, crystallization, x-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
01/16/2001CA2093659C Dna sequence encoding bovine .alpha.-lactalbumin and methods of use
01/16/2001CA2076979C Substantially pure transforming growth factor-.beta.-1-binding protein and nucleotide sequences expressing the binding protein
01/16/2001CA2029861C Diagnosis and treatment of insulin dependent diabetes mellitus
01/16/2001CA1341172C Synthetic insecticidal crystal protein gene
01/16/2001CA1341170C Calcium channel compositions and methods
01/16/2001CA1341169C Factor viii analog, process for its preparation and composition containing it
01/16/2001CA1341167C Transformation and foreign gene expression in brassica species
01/16/2001CA1341166C Antigenic proteins and vaccines containing them for prevention of coccidiosis
01/16/2001CA1341165C Active site modified protease alpha-1-antitrypsin inhibitors and their production
01/14/2001CA2313869A1 Genotyping biallelic markers
01/11/2001WO2001003149A1 Magnetic particle composition
01/11/2001WO2001002866A1 Diagnostics and therapeutics for arterial wall disruptive disorders
01/11/2001WO2001002861A1 Detection using dendrimers bearing labels and probes
01/11/2001WO2001002609A2 Method of identifying toxic agents using differential gene expression
01/11/2001WO2001002608A1 Oligonucleotides incorporating both 2-aminoadenine and 5-substituted pyrimidines
01/11/2001WO2001002607A1 Adenovirus carrying gag gene hiv vaccine
01/11/2001WO2001002605A1 Method for identifying a compound that modulates the function of the gene product of an essential gene
01/11/2001WO2001002604A1 Use of the krit1 gene in angiogenesis
01/11/2001WO2001002594A2 DNA CONSTRUCTS BASED ON THE eIF4A GENE PROMOTER
01/11/2001WO2001002593A2 Control of gene expression in eukaryotic cells
01/11/2001WO2001002592A2 Dna encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5a, transgenic plants and a method for controlling senescence and programmed cell death in plants
01/11/2001WO2001002591A1 Plants expressing δ6-desaturase genes and oils from these plants containing pufas and method for producing unsaturated fatty acids
01/11/2001WO2001002590A2 Plants with modified gene expression
01/11/2001WO2001002589A2 Methods, compositions and genetic sequences for modulating flowering in plants, and plants genetically modified to flower early and tardily
01/11/2001WO2001002588A2 Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
01/11/2001WO2001002587A2 Novel antifungal agents and fungicides, method for the production thereof and their use
01/11/2001WO2001002586A1 Human alpha 1,2-mannosidase
01/11/2001WO2001002585A1 Gene encoding cyclic lipopeptide acylase and expression of the same
01/11/2001WO2001002584A1 Dna encoding sucrose pts enzyme ii
01/11/2001WO2001002583A2 Orynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
01/11/2001WO2001002580A1 Vectors, cells and processes for pyrimidine deoxyribonucleosides production
01/11/2001WO2001002579A1 SYNTHETIC cryIC GENE AND TRANSGENIC PLANTS EXPRESSING SAME
01/11/2001WO2001002578A1 Global regulators of bacterial pathogenic genes; bacterial autoinducer inactivation protein, as targets for engineering disease resistance
01/11/2001WO2001002577A1 Pseudomonas aeruginosa antigens
01/11/2001WO2001002576A1 The lactose operon of lactobacillus delbrueckii and its use for controlling gene transcription and/or expression in bacterial cells
01/11/2001WO2001002575A1 Chlamydia antigens and corresponding dna fragments and uses thereof
01/11/2001WO2001002574A1 Negative regulators of systemic acquired resistance
01/11/2001WO2001002573A1 Genetic control of flowering using the fwa gene
01/11/2001WO2001002572A1 Genetic control of flowering using the fwa gene
01/11/2001WO2001002571A2 An interleukin-1 receptor antagonist and uses thereof
01/11/2001WO2001002570A1 Delivery of trefoil peptides
01/11/2001WO2001002569A2 Human immune response molecules
01/11/2001WO2001002568A2 Human genes and gene expression products
01/11/2001WO2001002567A1 16405 receptor, a g-protein coupled receptor
01/11/2001WO2001002566A1 Metabotropic glutamate receptors and methods of use therefor
01/11/2001WO2001002565A2 Secreted protein zacrp4
01/11/2001WO2001002564A1 Novel polypeptide and dna thereof
01/11/2001WO2001002563A2 HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
01/11/2001WO2001002562A1 Placental organic anion transporter and gene thereof
01/11/2001WO2001002561A2 Mammalian calcium channels and related probes, cell lines and methods
01/11/2001WO2001002560A1 Novel genes and their use in the modulation of obesity, diabetes and energy imbalance
01/11/2001WO2001002559A1 Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
01/11/2001WO2001002557A1 Neurotrophic factor receptor
01/11/2001WO2001002556A2 Agents for the diagnosis, prognosis and treatment of malignant diseases
01/11/2001WO2001002555A1 Method of making and identifying attenuated microorganisms, compositions utilizing the sequences responsible for attenuation, and preparations containing attenuated microorganisms
01/11/2001WO2001002554A2 Method for high-throughput selection of interacting molecules
01/11/2001WO2001002553A2 Dna binding protein and sequence as insulators having specific enhancer blocking activity for regulation of gene expression
01/11/2001WO2001002552A2 Double transgenic animals as models for neurodegenerative disease
01/11/2001WO2001002551A2 Virus like particles, preparation and use in screening and functional genomics
01/11/2001WO2001002550A2 Cell death related drug targets in yeast and fungi
01/11/2001WO2001002549A2 Homomeric and heteromeric ampa receptors
01/11/2001WO2001002547A1 Process for producing l-lysine
01/11/2001WO2001002546A1 Process for producing l-amino acid
01/11/2001WO2001002545A1 Process for producing l-amino acid