Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
02/2001
02/27/2001US6194563 Solid phase nucleic acid labeling by transamination
02/27/2001US6194562 Endotoxin reduction in nucleic acid purification
02/27/2001US6194561 Oligonucleotide probes of defined nucleotide sequences which are complementary to second exon of class ii hla beta chain gene; diagnosis of susceptibility to insulin-dependent diabetes mellitus and pemphigus vulgaris; antidiabetic agents
02/27/2001US6194560 Synthetic escherichia coli gene which encodes lt-b; the dna sequence is optimized for plant codon usage; feeds; foods
02/27/2001US6194559 Abscisic acid responsive element-binding transcription factors
02/27/2001US6194557 Nucleic acid molecules encoding Bap-1 proteins
02/27/2001US6194556 Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor
02/27/2001US6194550 Synthesizing nucleic acid mixture including messenger rna, synthesizing mixture of nucleic acid*polypeptide conjugate (copolymer) which does not contain ribosome, then partitioning by affinity to a target molecule
02/27/2001US6194549 Partially purified preparation of pen5, a glycoprotein pair; for detecting and/or removing natural killer cells from a mixed population of cells
02/27/2001US6194547 ETS2 repressor factor (ERF)
02/27/2001US6194546 Influenza virus haemagglutinin which has a heterologous epitope at antigenic site a; vaccines against foot-and-mouth disease, poliovirus, human rhinovirus, hepatitis b virus, plasmodium and bacteria
02/27/2001US6194542 Method of detecting cytomegalovirus (CMV)
02/27/2001US6194390 Administering hydroxyurea and a 2'-fluoropurine-dideoxy-nucleoside selected from the group of 2'-fluoro-2',3'-dide-oxyadenosine,-dideoxyinosine, and -dideoxyguanosine with a carrier or excipient; viricides; retroviruses; plant viruses
02/27/2001US6194389 Particle-mediated bombardment of DNA sequences into tissue to induce an immune response
02/27/2001US6194388 Immunomodulatory oligonucleotides
02/27/2001US6194385 Calcium-binding protein
02/27/2001US6194212 Increasing gene expression by transducing eukaryotic cells with retrovirus vector having heterologous gene linked to regulatory sequence and scaffold attachment region of human interferon-beta gene, allowing cells to rest and express gene
02/27/2001US6194211 Transcriptional regulatory sequence of carcinoembryonic antigen for expression targeting
02/27/2001US6194207 Methods for the selective expansion of lymphocytes by in vitro cultivation
02/27/2001US6194206 Use of oligonucleotide telomerase inhibitors to reduce telomere length
02/27/2001US6194205 Multistep process using conditionally immortalized antigen-presenting cells which are engineered to express antigen of interest, adding leukocytic cells, and culturing mixture to activate the t cells
02/27/2001US6194202 Parthenogenic oocyte activation
02/27/2001US6194201 Expression system for anaerobic gene expression in higher plants
02/27/2001US6194200 Expression systems for preparation of polypeptides in prokaryotic cells
02/27/2001US6194191 Method for the production and purification of adenoviral vectors
02/27/2001US6194190 From pyrococcus which can release two or more blocking groups selected from acetyl group, pyroglutamyl group, formyl group and myristoyl group, from protected peptides; use in kits for analyzing an amino acid sequence
02/27/2001US6194187 Apoptosis-inducing protein and gene encoding the same
02/27/2001US6194186 Human protein kinase and kinase inhibitors
02/27/2001US6194185 Recombinant materials and methods for production of limonene hydroxylases
02/27/2001US6194183 Preparing polypeptide for use in surfactants; providing transformed phage, incubate with surfactants to deactivate polypeptide, separate phage that display variant polypeptides, isolated phage sequences of variant and determine sequence
02/27/2001US6194180 Nucleic acid enzymes for cleaving DNA
02/27/2001US6194179 Method for preparing polynucleotide sequences and uses thereof
02/27/2001US6194176 Recombinant expression of proteins from secretory cell lines
02/27/2001US6194175 Nucleotide sequences coding suppressor of transcriptional activity; for treating adult respiratory distress syndrome, allograft rejection, asthma, arthritis, cancer and restenosis; anticarcinogenic agents
02/27/2001US6194174 Histidine kinase, 636 HK, of staphylococcus aureus
02/27/2001US6194173 Binding proteins for phosphoinositides, GRP1 or general receptor 1 for phophoinositide
02/27/2001US6194172 Cytokine designated lerk-6
02/27/2001US6194171 Also vectors, transformed cells; useful for expression in cells for the purposes of identifying agonists or antagonists of ataxin-2-binding protein function
02/27/2001US6194170 MurF of Streptococcus pneumoniae
02/27/2001US6194168 Regulatory nucleotide sequences for the transcription of heterologous transcripts for producing viral, prokaryotic, and eukaryotic polypeptides
02/27/2001US6194167 ω-3 fatty acid desaturase
02/27/2001US6194166 Isolated dna; genetic engineering
02/27/2001US6194163 Method for the quantitative measurement of human acute phase serum amyloid A protein; recombinant protein; specific antibody
02/27/2001US6194162 Method of screening for compounds that bind P2x receptor
02/27/2001US6194161 Staphylococcus aureus antigen
02/27/2001US6194156 Isolated nucleic acid molecules which encode TAGE molecules, and uses thereof
02/27/2001US6194154 Diagnosing cancerous transformation of human cells
02/27/2001US6194153 Methods for determining risk of developing alzheimer's disease by detecting mutations in the presenilin 1 (PS-1) gene
02/27/2001US6194152 Nucleotide sequences for the diagnosis and treatment of human urogenital cancers
02/27/2001US6194151 Nucleotide sequences coding binding polypeptide; for the detection of modulators of tumor necrosis factor activity; for the treatment of cell proliferation and differentiation defects
02/27/2001US6194150 Nucleic acid based inhibition of CD40
02/27/2001US6194149 Target-dependent reactions using structure-bridging oligonucleotides
02/27/2001US6194145 Amplifying microorganism nucleotide sequences; hybridizing two preferential primers to nucleotide sequences, expanding primers, separating expansion products and miroorganism nucleotide sequences, duplicate the process
02/27/2001US6194142 Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2, and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
02/27/2001US6194140 HCV NS3 protein fragments having helicase activity and improved solubility
02/27/2001US6193984 Pharmaceutical composition of herpes simplex virus typ-1 (HSV-1) glycoproteins
02/27/2001US6193981 Methods and compositions for impairing multiplication of HIV-1
02/27/2001US6193980 Replication defective herpes simplex virus comprising heterologous inserts
02/27/2001US6193972 Hybrid heterodimeric protein hormone
02/27/2001US6193971 Dictyocaulus viviparus antigen for diagnosing lungworm infestation and for vaccination
02/27/2001US6193966 Administering bispecific protein or peptide molecule, comprising a first binding determinate which binds to fc.alpha.receptor without being blocked by immunoglobulin a and second binding determinant which binds to target antigen
02/27/2001US6193965 Administering therapeutically effective amount of reagent which modulates kinase activity for treating cell proliferative disorder associated with c-jun n-terminal kinase disorder,
02/27/2001US6193963 Method of treating tumor-bearing patients with human plasma hyaluronidase
02/27/2001US6193948 Contacting sample with purified hu antigenic polypeptide to form complex between purified hu antigenic polypeptide and antibody, detecting presence of complex formed to detect antibody associated with paraneoplastic sensory neuronopathy
02/27/2001US6193866 Separation of charged particles by a spatially and temporally varying electric field
02/27/2001US6193595 Methods and apparatus for performing processing operations on a slaughtered animal or part thereof
02/27/2001CA2316036A1 Repressing gene expression in plants
02/27/2001CA2232789C Method for treating alzheimer's disease using glial cell line-derived neurotrophic factor (gdnf) protein product
02/27/2001CA2195784C Fumonisin-detoxifying enzymes
02/27/2001CA2025598C Chimaeric hepadnavirus core antigen proteins
02/27/2001CA2022177C Arginine deiminase, its manufacturing method, and an anti-cancer agent containing this enzyme as an effective ingredient
02/27/2001CA1341192C Process for the preparation of a protein by yeasts using an inducible system, corresponding vectors and transformed strains
02/27/2001CA1341191C Detection of neu gene expression and products
02/27/2001CA1341190C Process for the integration of a chosen gene into a chromosome of a bacteria, and bacteria obtained by the process
02/22/2001WO2001013268A2 Specific identifiers of amino-acid and base sequences
02/22/2001WO2001013117A2 Proteins, genes and their use for diagnosis and treatment of breast cancer
02/22/2001WO2001013096A1 Device and method for determining multiple analytes
02/22/2001WO2001012861A1 Gene cloning
02/22/2001WO2001012859A2 Detection of differences in nucleic acids by inhibition of spontaneous dna branch migration
02/22/2001WO2001012856A2 Analysis of sequence tags with hairpin primers
02/22/2001WO2001012855A2 Binary encoded sequence tags
02/22/2001WO2001012854A2 Color compensation for temperature and electronic gains
02/22/2001WO2001012852A2 Polymerase extension at 3' terminus of pna-dna chimera
02/22/2001WO2001012850A1 Non-sporulating basidomycetes
02/22/2001WO2001012849A1 Method of distinguishing nucleic acids and kits for nucleic acid test
02/22/2001WO2001012846A1 Preparation of metal oxide supports loaded with biomolecules
02/22/2001WO2001012845A1 Screening for udp-glucose: glycoprotein glucosyltransferase (uggt) activity
02/22/2001WO2001012840A2 Anti-epha2 antibodies as a cancer diagnostic
02/22/2001WO2001012835A1 Hiv-1 primers for uracil deglycosylase-based cloning
02/22/2001WO2001012833A2 Process for the biological production of 1,3-propanediol
02/22/2001WO2001012830A1 Adenoviral vectors including dna sequences encoding angiogenic inhibitors
02/22/2001WO2001012829A2 Replication deficient baculovirus expression system
02/22/2001WO2001012828A1 Methods and apparatus for transformation of monocotyledenous plants using agrobacterium in combination with vacuum filtration
02/22/2001WO2001012827A2 Method for production of transgenic plants with increased tocopherol content
02/22/2001WO2001012826A2 Nucleic acid molecules derived from plants which code for enzymes which are involved in the synthesis of starch
02/22/2001WO2001012825A1 Herbicide-tolerant protoporphyrinogen oxidase
02/22/2001WO2001012824A1 Means and methods for modifying gene expression using unpolyadenylated rna
02/22/2001WO2001012822A1 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
02/22/2001WO2001012821A1 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
02/22/2001WO2001012820A1 Genetic system and self-cleaving inteins derived therefrom, bioseparations and protein purification employing same, and methods for determining critical, generalizable amino acid residues for varying intein activity