Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/2001
06/05/2001US6242590 Antisense modulation of zinc finger protein-217 expression
06/05/2001US6242587 Nucleotide and amino acid sequences for protein expressed in platelets that interacts with integrin alpha iib cytoplasmic domain to activate the fibrinogen receptor; drug screening of agonists and antagonists; anticoagulants; vectors; host cells
06/05/2001US6242586 Amino acid sequence of t cell surface antigen; fusion proteins; treatment of autoimmune diseases; antiarthritic agents; antiinflammatory agents; immunosuppressants; diagnosis; recombinant production
06/05/2001US6242584 Method for identifying mycobacterial species by comparative sequence analysis of rpoB gene
06/05/2001US6242579 Antigen found on a small subset of human hematopoietic cells which binds to monoclonal antibody MG1
06/05/2001US6242578 Glycoconjugate of carbohydrate covalently bound to peptide of defined amino acid sequence; prevention of influenza virus binding to cells, treatment of schizophrenia, and diagnosis of chronic viral diseases related to cancer
06/05/2001US6242576 Antibodies which bind to protein coded by specific nucleotide sequence; diagnosis and therapy
06/05/2001US6242575 Antibodies for detecting p27 protein
06/05/2001US6242574 Antimicrobial proteins
06/05/2001US6242572 Human G protein coupled lysophosphatidic acid receptor
06/05/2001US6242570 Recombinant fusion protein of two or more erythropoietin molecules; has prolonged plasma half-life; treatment or prevention of anemia
06/05/2001US6242568 Zinc finger protein derivatives and methods therefor
06/05/2001US6242566 Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells
06/05/2001US6242427 Methods of inhibiting phagocytosis
06/05/2001US6242419 Genes encoding proteins expressed in lymph node stromal cells from flaky skin (fsn-/-) mice and their use in therapy.
06/05/2001US6242418 Therapeutic uses of BPI protein products for human meningococcemia
06/05/2001US6242416 Inhibition of β-amyloid binding to the p75 nerve growth factor receptor
06/05/2001US6242259 Compositions and methods for packing of alphavirus vectors
06/05/2001US6242258 Covalently linking nucleic acid to photolabile caging group which reversibly prevents expression, introducing nucleic acid into cell, exposing cell to light to remove caging group and allow gene expression; gene therapy
06/05/2001US6242257 Tissue culture process for producing a large number of viable cotton plants in vitro
06/05/2001US6242256 Nucleic acid which encodes an n-acetyl-gamma-glutamyl phosphate reductase of specific amino acid sequence; transgenic seeds and plants; transformed host cells
06/05/2001US6242254 Cell has dna encoding tetracycline responsive transcriptional activator linked to tissue-specific promoter and tetracycline operator minimal promoter linked to dna encoding sv40 t antigen; cell proliferation is controlled by tetracycline
06/05/2001US6242251 Polynucleotide which codes for polypeptide receptor of defined amino acid sequence having affinity for neuropeptide y, pancreatic polypeptide, or peptide yy; transfected host cells; drug screening
06/05/2001US6242250 Determined DNA sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
06/05/2001US6242249 Nucleotide sequences of trigger factor chaperones from staphylococcus; diagnosis; probes; primers; vaccines; bactericides; bacteriostats; antibodies; drug screening
06/05/2001US6242246 Making a biochip by identifying distinct nucleic acid ligand to target molecule using selex (systematic evolution of ligands by exponential enrichment) methods then attaching ligands to spatially discrete locations on solid support
06/05/2001US6242241 Nucleotide and amino acid sequences; transgenic plants; transformed host cells
06/05/2001US6242238 Nucleotide sequence which codes for heparinase; drug screening for antimetastasis/antinflammatory agents, angiogenesis inhibitors, wound healing agents; treatment for angioplasty-induced restenosis and atherosclerosis
06/05/2001US6242237 Dna construct encoding a galactanase having ph optimum above 5.9 from myceliophthora thermophila or humicola insolens; animal feed additive; wine and juice processing
06/05/2001US6242236 Generating hydrolytic enzyme by selecting catalytic domain sequence, inserting into cell so that sequence can undergo immunoglobulin superfamily diversification, culturing cell or progeny, identifying enzymes having desired activity
06/05/2001US6242234 Mutants of formate dehydrogenase from Candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases
06/05/2001US6242232 Amino acid and nucleotide sequences; recombinant production
06/05/2001US6242228 Efficient production by allowing protein of defined amino acid sequence to act on d-xylulose, then recovering produced xylitol
06/05/2001US6242225 Process for processing sucrose into glucose and fructose
06/05/2001US6242222 Using first mutagenic primer nucleic acid or analog to hybridize to first target sequence for polymerase chain reactions, producing first mutagenized nucleic acid, using second primer to produce second mutagenized nucleic acid
06/05/2001US6242221 Genomic polyphenol oxidase gene fragments of plants
06/05/2001US6242220 Method for purifying covalently closed circular DNA
06/05/2001US6242219 Methods for recombinant peptide production
06/05/2001US6242218 Dna construct for altering gene expression of endogenous granulocyte-colony stimulating factor in mammalian cell; gene therapy; culture production
06/05/2001US6242217 Nucleotide sequence coding polypeptides for the treatment of cancer, cardiovascular diseases, inflammatory, kidneys defects, pain, psychological disorders and nervous system disorders
06/05/2001US6242216 Nucleic acids encoding a functional human purinoreceptor P2X2 and P2X4, and methods of production and use thereof
06/05/2001US6242213 Nucleotide sequences coding preferential polypeptide for use in controlling immune response
06/05/2001US6242212 Nucleotide sequences which code a protein for the diagnosis, detection and treatment of cancer
06/05/2001US6242211 Methods for generating and screening novel metabolic pathways
06/05/2001US6242209 Cell flow apparatus and method for real-time measurements of cellular responses
06/05/2001US6242204 Methods of detecting non-small cell lung carcinoma and ovarian cancer
06/05/2001US6242201 Detection of protein that preferentially binds to proliferating cells; for the treatment of psoriasis, cancer and cell proliferative defect
06/05/2001US6242199 Detecting ligand associated with hormone release; transform cells with vector, transform cells with vector coding light protein, incubate cells with binding protein, detect binding activity
06/05/2001US6242194 Transcriptional regulatory sequences for the control of transcription of preferential ribonucleic acid sequences
06/05/2001US6242192 Expression of heterologous protein in cells; insert vector into cells, culture transformed cells and recover preferential gene products
06/05/2001US6242189 Recovering microorganismal nucleotide sequences; incubate microoganismal lysate with enzyme which adjusts terminals, recover adjusted products
06/05/2001US6242188 Sample processing to release nucleic acids for direct detection
06/05/2001US6242187 Evaluating receptivity to hepatitus virus; insert vector into cells, culture cells, measure expression of indicator gene in target cell, compare expression of indicator gene in the presence and absence of viricides
06/05/2001US6242185 Purified nucleic acid encoding transcription factor regulatory protein
06/05/2001US6242183 Interaction trap systems for detecting protein interactions
06/05/2001US6242182 Methods for haplotyping Rfp-Y and B-F genes in chicken
06/05/2001US6242181 Detecting genetic rearrangement which leads to a form of blood pressure defect; compare wild type and mutant nucleotide sequences for rearrangements, the presence of rerrangements indicate potential blood pressure defect
06/05/2001US6242179 Nucleotide sequences coding eukaryotic hydrolase; for the diagnosis, prevention, and treatment of immune defects and cancers; anticarcinogenic agents
06/05/2001US6242177 Methods and compositions for secretion of heterologous polypeptides
06/05/2001US6241991 Aviadenovirus
06/05/2001US6241989 Recombinant multivalent viral vaccine
06/05/2001US6241982 Method for treating brain cancer with a conditionally lethal gene
06/05/2001US6241980 Removal of substances which interfere with hybridization and/or amplification of nucleic acids
06/05/2001US6241710 Hypodermic needle with weeping tip and method of use
06/05/2001CA2168429C Expression of fusion polypeptides transported out of cytoplasm without leader sequences
06/05/2001CA2155335C Improved method for the refolding of proteins
06/05/2001CA2155185C Totally synthetic affinity reagents
06/05/2001CA2124937C T-pa substitution variants with improved fibrin-specificity
06/05/2001CA2112408C Monoclonal antibody to lymphocyte-associated cell surface protein
06/05/2001CA2005502C Somatotropin analogs
06/05/2001CA1341246C Somatic cell gene therapy
06/05/2001CA1341245C Recombinant vaccinia virus mva
06/05/2001CA1341242C Dna sequence, vectors, recombinant viruses, and process involving recombinant cowpox viruses capable of multiplying in cho cells
06/05/2001CA1341241C Expression of a tumor-specific antigen through a recombinant virus vector, and its use for prevention or cure of the corresponding tumor
06/05/2001CA1341240C Dna encoding human tumor necrosis factor and human tumor necrosis factor polypeptide
06/04/2001WO2001042474A2 Interferon-like molecules and uses thereof
06/04/2001CA2395408A1 Interferon-like molecules and uses thereof
06/02/2001CA2325594A1 Novel nucleotide sequences coding for the gpm gene
06/02/2001CA2325227A1 New nucleotide sequences coding for the glk-gene
06/01/2001CA2324787A1 Personal gene library
05/2001
05/31/2001WO2001039004A1 Employing synthetic genes in genetic algorithms, information encoding and non-replicative encryption
05/31/2001WO2001038874A1 Expression cloning method
05/31/2001WO2001038872A2 Assay of isomerised and/or optically inverted proteins
05/31/2001WO2001038584A2 Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof
05/31/2001WO2001038583A2 Capillary array-based sample screening
05/31/2001WO2001038582A1 CATALYTIC RNAs WITH AMINOACYLATION ACTIVITY
05/31/2001WO2001038580A2 Nucleic acid probe arrays
05/31/2001WO2001038574A1 Dna sequencing method which employs various dna polymerases and kit used for the same
05/31/2001WO2001038573A1 Dna sequencing method which employs various nucleotide mixtures and kit used for the same
05/31/2001WO2001038572A1 Method of amplifying nucleic acids
05/31/2001WO2001038571A1 Mismatch-recognizing molecules
05/31/2001WO2001038570A1 Oligonucleotides and assemblies thereof useful in the detection of the presence or absence of target nucleic acid sequences in a sample
05/31/2001WO2001038569A1 Methods for detecting polypeptides regulating signal transduction pathways
05/31/2001WO2001038568A2 Automated method for identifying related biomolecular sequences
05/31/2001WO2001038566A2 Screening method for candidate drugs
05/31/2001WO2001038565A2 Oligomer array with pna and/or dna oligomers on a surface
05/31/2001WO2001038564A2 Loci for idiopathic generalized epilepsy, mutations thereof and method using same to assess, diagnose, prognose or treat epilepsy
05/31/2001WO2001038557A1 Method of screening multiply transformed cells using bicistronic expression of fluorescent proteins
05/31/2001WO2001038552A2 Excipient system that contains coating substances with enzymatically removable side-groups
05/31/2001WO2001038551A1 Regulation of polycomb group gene expression for increasing seed size in plants