Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/2002
08/27/2002US6441160 Hydrophobic interaction chromatography using packing material with functional group introduced to adsorb nucleic acids that exhibit certain hydrophobicity
08/27/2002US6441159 Phosphoramidite reagent with protected aromatic aldehyde used to introduce aldehyde group into oligonucleotide during standard automated synthesis so it can react with nucleophilic nh2 (semicarbazide) groups linked to the solid support
08/27/2002US6441158 Oligomers that bind to ku protein
08/27/2002US6441155 Isolated polynucleotide
08/27/2002US6441154 Human proteases and polynucleotides encoding the same
08/27/2002US6441153 Human carboxypeptidases and polynucleotides encoding the same
08/27/2002US6441151 Isolated nucleic acids
08/27/2002US6441149 Isolated nucleic acids
08/27/2002US6441148 Method for isolation of xylanase gene sequences from soil DNA, compositions useful in such method and compositions obtained thereby
08/27/2002US6441147 Batch commercial scale isolation of concentrated, active natural or recombinant proteins from intercellular material via vacuum and centrifugation; nondestructive to plants; pharmaceutical quality enzymes, cytokines and antibodies
08/27/2002US6441143 Identifying cancer patients with greatest probability of relapse; monoclonal antibody which binds to denatured epitope comprising a subset of amino acid residues 96-191; stomach, breast, lung, pancreatic, prostate or ovarian tumors
08/27/2002US6441140 Production of motif-specific and context-independent antibodies using peptide libraries as antigens
08/27/2002US6441137 Tie-2 ligands; tie= ?tyrosine kinase with ig (immunoglobulins) and egf (epidermal growth factor) homology domains?; tumor neovascularization
08/27/2002US6441136 Polypeptide of given amino acid sequence, modified by deleting amino acids near binding domains to prevent reaction with polyethylene glycol during conjugation to provide conjugated peptides with no decrease in activity
08/27/2002US6441135 Bak binding protein, DNA encoding the protein, and methods of use thereof
08/27/2002US6441132 Of given amino acid sequence (6-12 amino acids), including d-tryptophan residues; useful as anticonvulsant or neuroprotective agents
08/27/2002US6441130 Form triple stranded structures with nucleic acids
08/27/2002US6440935 Such as cecropins and sarcotoxins
08/27/2002US6440743 Supplying immobilizated polynucleotides
08/27/2002US6440742 Recombinant AAV vector-based transduction system and use of same
08/27/2002US6440741 Expression vector for consistent cellular expression of the tet on repressor in multiple cell types
08/27/2002US6440739 Polypeptides; anticancer agent; wound healing agents
08/27/2002US6440738 Polynucleotides
08/27/2002US6440737 Antisense modulation of cellular apoptosis susceptibility gene expression
08/27/2002US6440736 Altering the properties of cells or of particles with membranes derived from cells by means of lipid-modified proteinaceous molecules
08/27/2002US6440735 Dendritic cell vaccine containing telomerase reverse transcriptase for the treament of cancer
08/27/2002US6440732 Checkpoint/repair genes involved with dna repair prior to replication; aging resistance; cancer therapy
08/27/2002US6440730 Retroviral hybrid vectors pseudotyped with LCMV
08/27/2002US6440728 Making eukaryotic gene transfer vectors comprising homologous recombining lambdid vectors with a second dna in a bacterium; capsids; amplicons
08/27/2002US6440727 Proteinase inhibitor, precursor thereof and genetic sequences encoding same
08/27/2002US6440726 Gene therapy; cardiovascular diseases; for stimulating the formation, maturation or regression of blood vessels
08/27/2002US6440724 Method and device for preparing samples for detecting a nucleotide sequence
08/27/2002US6440720 For use in recombinant protein production systems
08/27/2002US6440719 Method and reagent for inhibiting herpes simplex virus replication
08/27/2002US6440718 Recombination to produce hepatitis a virus; gene expression
08/27/2002US6440717 BPN′ variants having decreased adsorption and increased hydrolysis
08/27/2002US6440707 Fluorescence polarization in nucleic acid analysis
08/27/2002US6440706 Digital amplification
08/27/2002US6440705 Detection of variance in nucleotide sequence without the need for full sequence determination; genotyping and labeling while cleaving dna strands; electrophoresis
08/27/2002US6440702 For treatment of motor neuron diseases and muscle degenerative diseases; screening for therapeutic proteins by determining altered electrophoretic binding properties
08/27/2002US6440701 Transferrin receptor genes of Moraxella
08/27/2002US6440700 Method of combinatorial protein synthesis based on ribosomal frameshifting
08/27/2002US6440695 Method for producing diverse libraries of encoded polypeptides
08/27/2002US6440694 Which is a tumor necrosis factor (tnf) homolog of given nucleotide sequence and amino acid sequence
08/27/2002US6440693 Given amino acid sequence; recombinant tumor necrosis factor (tnf)-binding protein useful in pharmaceuticals for inhibiting tnf
08/27/2002US6440688 Organism transformed to express said enzyme; oxidizes nad to nadh and reduces nadph to nadp, for use as biocatalyst in reacting morphine to hydromorphone
08/27/2002US6440681 Using isolated dnas encoding human alpha and beta subunits of the receptors and the polypeptides encoded thereby; measuring ion flux, electrophysiological response; drug screening
08/27/2002US6440680 Using dna encoding the novel prostaglandin receptor and host cells expressing the receptor
08/27/2002US6440679 Dermatomyositis-specific auto-antigen
08/27/2002US6440674 Plant promoter derived from luminal binding protein gene and methods for its use
08/27/2002US6440668 Method of DNA shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process
08/27/2002US6440666 Detecting alleles of a gene responsible for autosomal dwarfism in chickens by hybridizing nucleic acid probe(s) derived from a recombinant nucleic acid associated with autosomal dwarfism in chicken
08/27/2002US6440664 Fluorescent tags distinguishable on the basis of their excitation or emission spectra; after electrophoresis, the order of the detected peaks is used to call the base sequence; data processor
08/27/2002US6440661 By polymerase chain reaction (pcr) amplification using specific oligoprimers
08/27/2002US6440660 Oligonucleotide mediated reversal of drug resistance
08/27/2002US6440657 Chemically synthesized env peptide of human immunodeficiency virus (hiv) of given amino acid sequence; use as diagnostic reagent
08/27/2002US6440656 Methods for the inhibition of respiratory syncytial virus transmission
08/27/2002US6440425 High molecular weight major outer membrane protein of moraxella
08/27/2002US6440424 High molecular weight major outer membrane protein of moraxella
08/27/2002US6440422 Expressing foreign genes inserted at site of naturally occurring deletion in modified vaccinia virus ankara genome; polypeptides, e.g. antigens or therapeutic agents, or viral vectors for gene therapy; encoding antigens as vaccines
08/27/2002US6440418 Variable light and heavy amino acid sequences encoded by nucleic acid sequences; seq id no:24, 25 and 26; rheumatoid arthritis, multiple sclerosis, diabetes, and systemic lupus erythematosus; graft versus host disease; gene therapy
08/27/2002US6440412 Purified forms of DNase
08/27/2002US6440409 Method for efficient and highly selective control of microorganisms
08/27/2002US6440407 Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 (IL-3) multiple mutation polypeptides
08/27/2002CA2233079C Method for characterizing nucleic acid molecules
08/27/2002CA2231738C Stress resistant plant in which cell death suppressing gene is introduced and method for producing the same
08/27/2002CA2142910C A method for the purification and separation of nucleic acid mixtures by chromatography
08/27/2002CA2125403C Novel tissue plasminogen activator variants
08/27/2002CA2069929C Pharmaceutical composition having an endoproteolytic activity; a process for endoproteolytically processing (precursor) proteins and for the (micro)biological production of proteins
08/27/2002CA2018592C Polypeptides and polypeptide analogues with inhibitory activity against human elastase
08/26/2002CA2372793A1 Method of agrobacterium mediated plant transformation through treatment of germinating seeds
08/22/2002WO2002065136A2 Yeast screens for agents affecting protein folding
08/22/2002WO2002065093A2 Methods and compositions of amplifying rna
08/22/2002WO2002065091A2 Pin1 as marker for abnormal cell growth
08/22/2002WO2002064841A1 Methods of using mammalian rnase h and compositions thereof
08/22/2002WO2002064840A2 Methods for identifying compounds that inhibit or reduce ptp1b expression
08/22/2002WO2002064836A1 Antisense modulation of protein phosphatase 2 catalytic subunit alpha expression
08/22/2002WO2002064834A1 Novel two-hybrid system and use thereof
08/22/2002WO2002064833A1 Method of detecting nucleotide polymorphism
08/22/2002WO2002064832A1 Method of examining allergic disease
08/22/2002WO2002064827A2 Nucleic acids of the human abca12 gene, vectors containing such nucleic acids, and uses thereof
08/22/2002WO2002064824A2 Oligonucleotide probes used to detect parodontopathogenic bacteria by in situ hybridization
08/22/2002WO2002064820A1 Dna markers for meat tenderness
08/22/2002WO2002064817A2 Use of bacteria in a method for producing cellulose
08/22/2002WO2002064814A2 Expression of human milk proteins in transgenic plants
08/22/2002WO2002064808A1 Method for l-threonine production
08/22/2002WO2002064806A2 A process for the fermentative preparation of d-pantothenic acid and/or its salts
08/22/2002WO2002064805A2 Replication competent non-mammalian retroviral vectors
08/22/2002WO2002064804A2 A bi-directional dual promoter complex with enhanced promoter activity for transgene expression in eukaryotes
08/22/2002WO2002064803A2 Identification of seeds or plants using phenotyic markers
08/22/2002WO2002064802A2 Regulatory genes suitable for use in gene expression
08/22/2002WO2002064801A1 Molecular control of transgene escape by a repressible excision system
08/22/2002WO2002064800A1 Plasmid shuttle vector between escherichia coli and brevibacillus
08/22/2002WO2002064799A2 Optimized messenger rna
08/22/2002WO2002064798A1 Dna sequences differentially expressed in tumour cell lines
08/22/2002WO2002064797A2 Mitochondrial topoisomerase i
08/22/2002WO2002064796A2 Butyrylcholinesterase polypeptide variants with increased catalytic efficiency and methods of use
08/22/2002WO2002064795A2 Putative human enzymes
08/22/2002WO2002064794A2 Herbicide target genes and methods
08/22/2002WO2002064793A2 G protein-coupled receptor-like proteins and nucleics acids encoding same