Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
10/2002
10/02/2002DE10113265A1 Nucleic acids stabilized against exonucleases, useful for protein production in cell-free or cellular systems, contains molecules attached to bulky specific binding partners
10/02/2002DE10111083A1 Chitindeacetylase und Verfahren zu seiner Herstellung Chitin deacetylase and process for its preparation
10/02/2002DE10109147A1 Verpackungszelllinie für lentivirale Vektoren Packaging cell line for lentiviral vectors
10/02/2002CN1372642A Receptor analysis method
10/02/2002CN1372599A Plant sterol acryltransferases
10/02/2002CN1372598A Methods of inducing cell death
10/02/2002CN1372597A Method for producing L-amino acids by increasing cellular NADPH
10/02/2002CN1372596A Dihydroorotase extracted from plants
10/02/2002CN1372595A Method of inhibiting the formation of by-product in the production of genetically modified polypeptide
10/02/2002CN1372594A OX2 receptor homologs
10/02/2002CN1372569A Keratinocyte growth factor-2
10/02/2002CN1372568A Vaccin
10/02/2002CN1372473A Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide
10/02/2002CN1372436A Seedless fruit production
10/02/2002CN1372001A Human SP-A1 expression in pichia pastoris
10/02/2002CN1372000A Gene engineering body for somatostatin gene engineering subunit seedling
10/02/2002CN1371999A Double gene coexpression plasmid, construction method and application thereof
10/02/2002CN1371998A High temp ersistant triphosphate guanosine cyclohydrolase gene sequence and coded polypeptide and method for preparing said polypeptide
10/02/2002CN1371997A High temp. resistant dihydroorotic acid dihydrogenase gene sequence and coded polypeptide and method for preparing said polypeptide
10/02/2002CN1371996A High temp. resistant spermidine synthase sequence and coded polypeptide and method for preparing said polypeptide
10/02/2002CN1371995A Human peptide transport protein coding sequence, preparation method and use thereof
10/02/2002CN1371994A Recombinant hirudin expressed by using yeast secretary
10/02/2002CN1371919A Human like collagen and production method thereof
10/02/2002CN1371917A Liver cance high-expression gene, its coded protein and use
10/02/2002CN1371916A Human siali acid conjugated immunoglobulin-like agglutinant, its coding sequence and use
10/02/2002CN1371915A Novel human cell endocytic regulatory protein, its coding sequence and use
10/02/2002CN1371913A Novel polypeptide-human fasciclin and elongation protein 9.46 and polynucleotide for coding said polypeptide
10/02/2002CN1371597A Application of transgene paddy rice endosperm in genetics demonstration experiment
10/01/2002US6459019 Chimeric genes and methods for increasing the lysine and threonine content of the seeds of plants
10/01/2002US6459018 Gene expression of delta-six desaturase to produces stearidonic acid
10/01/2002US6459017 Transformation, incubation, bombardment with nucleic acid microparticle, callus formation; genetic engineering
10/01/2002US6458945 Detecting variance in nucleotide sequence; mixing adenosine-cytosine-, thymidine-, or uridine triphosphate with nucleotide in presence of polymerase
10/01/2002US6458944 Human BMP-4 promoter and method for exploring bone-related substance by using the same
10/01/2002US6458943 hD54 polynucleotides
10/01/2002US6458940 Genetic engineering
10/01/2002US6458934 Grafted complementarity determining regions to mouse monoclonal antibodies; amino acid replacements; autoimmune disease treatment and immunosuppressants; side effect reduction
10/01/2002US6458933 Specific for hla class ii invariant chain; side effect reduction of chemotherapy; drug clearance
10/01/2002US6458932 Dna cloning; gene expression; genetic engineering
10/01/2002US6458931 Immunoassay, immunotherapy; cancer; side effect reduction
10/01/2002US6458929 Myotilin, a novel actin-organizing protein
10/01/2002US6458928 Microbial swollenin protein, DNA sequences encoding such swollenins and method of producing such swollenins
10/01/2002US6458925 Peptide antagonists of zonulin and methods for use of the same
10/01/2002US6458764 GRF analogs with increased biological potency
10/01/2002US6458601 Dna analysis, immunology, genetic engineering; plurality of binding substances
10/01/2002US6458594 Using chimeric rna-dna oligonucleotide to implement nucleotide conversion; excision with recombinase; genetic engineering
10/01/2002US6458592 Transfecting antibody-producing cell with homology-targeting vector with lox site; genetic engineering and expression
10/01/2002US6458591 Diabetes treatment
10/01/2002US6458590 Methods and compositions for treatment of restenosis
10/01/2002US6458589 Hepatocyte lineage cells derived from pluripotent stem cells
10/01/2002US6458587 Transfecting cells with a recombinant adeno-associated virus (aav) which can be package into infectious aav virions, a helper aav vector essential for replication and packaging and a productive vector which cannot be packaged into the virion
10/01/2002US6458586 Replication of defective vectors with mutations and deletions; gene therapy, vaccines, genetic engineering
10/01/2002US6458584 Customized oligonucleotide microchips that convert multiple genetic information to simple patterns, are portable and reusable
10/01/2002US6458582 Bioreactor having a seal material which can be attached/detached to the opening of a reaction container automatically and continuously by a moveable sheet; gene analysis using the polymerase chain reaction
10/01/2002US6458581 Carrying out in vitro the complete developmental sequence culture of protozoa in an axenic liquid culture, serum-free and buffered; contains a basic medium for insect cells and an inorganic salt, a source of amino acids and a sugar
10/01/2002US6458578 Recombinant cell line produces adenoviral gene products E1 and DEF-A, and/or DEF-B
10/01/2002US6458575 Useful in the diagnosis, prevention, and treatment of cancer, autoimmune/inflammatory disorders, and reproductive disorders; screening libraries of peptides and antibodies; purification; amino acid sequences
10/01/2002US6458574 Highly purified alpha-galactose a glycoforms by charge alterations by increasing the sialic acid content and/or by increasing the phosphorylation; half-life; bioavailability; fabry's disease; cardiovascular disorders
10/01/2002US6458572 Phosphatidylglycerophosphate synthase from Staphylococcus aureus
10/01/2002US6458567 Hepatitis C Virus ribozymes
10/01/2002US6458566 Method of identification of differentially expressed MRNA
10/01/2002US6458565 Method for producing a heterologous secreted protein from chinese hamster ovary cells grown on microcarriers
10/01/2002US6458564 Amino acid sequence of the protease; for treating imbalance of desquamation
10/01/2002US6458563 Dna which encodes protein of defined amino acid sequence; stable, less immunogenic treatment of hemophilia
10/01/2002US6458562 Recombinant proteins of a Pakistani strain of hepatitis E and their use in diagnostic methods and vaccines
10/01/2002US6458561 Human NIM1 kinase
10/01/2002US6458560 Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
10/01/2002US6458559 Monovalent rna aptamer which binds drosophila splicing factor b52; for genetically engineered organisms
10/01/2002US6458557 Culturing microorganism in presence of formate where cell is transformed with polynucleotide sequence which encodes a formate transporter associated protein; production of proteins in culture
10/01/2002US6458551 Estrogen receptor
10/01/2002US6458546 Such as urine, blood, blood serum, and amniotic fluid; preservative includes a divalent metal chelator such as egta, edta or bapta with at least one chelator enhancing component such as lithium chloride, guanidine, sodium salicylate, etc.
10/01/2002US6458544 Methods for determining single nucleotide variations and genotyping
10/01/2002US6458543 Nucleic acid ligand diagnostic biochip
10/01/2002US6458540 Contacting nucleic acid sample with target-protecting molecule to form complex, digesting with enzymes to form at least one 5' single-stranded region, and detecting using reporter molecule; for diseases
10/01/2002US6458539 Detecting peptide or protein target in sample by exposing to non-naturally occuring photoaptamer where complexes not due to watson/crick base pairing occurs, irradiating to photocrosslink complexes, then determining complexes
10/01/2002US6458538 Methods of assaying for compounds that inhibit premature translation termination and nonsense-mediated RNA decay
10/01/2002US6458535 Detecting cleavage of nucleic acid cleavage structures using oligonucleotide probes and cleavage agents
10/01/2002US6458533 Determining which of a group of expressed sequence tags are complementary to a specific nucleic acid using biochip of immobilized oligonucoleotide probes
10/01/2002US6458532 Nucleotide and amino acid sequences; screening for increased susceptibility to manic-depressive disorder
10/01/2002US6458529 Assays for promoter operability in central nervous system cells
10/01/2002US6458527 Using synthetic or recombinant polypeptides as gag antigen; diagnosis of human immunodeficiency virus
10/01/2002US6458382 1,2-bis(oleoyloxy)-3-(4*-trimethylammino)propane, dioleoyl-and dilauroylphosphatidylethanolamine transfection reagents
10/01/2002US6458381 Lipids and their use, for example, in liposomes
10/01/2002US6458368 As vaccines for immunization
10/01/2002US6458366 Compounds and methods for diagnosis of tuberculosis
10/01/2002US6458364 Non-splicing variants of gp350/220
10/01/2002US6458362 Recombinant VP2 parvoviral pseudo-particles encoding CTL or T-helper cell epitopes
10/01/2002US6458360 Soluble complement regulatory molecules
10/01/2002US6458358 Compounds encoding the protective M-like protein of Streptococcus equi and assays therefor
10/01/2002US6458356 Antibody-induced apoptosis
10/01/2002US6458353 Anti-CCR2 antibodies and methods of use therefor
10/01/2002US6458350 ULBP DNA and polypeptides
10/01/2002US6458349 For treatment of leukemia, tumors, chronic infections, autoimmune disease, fibrotic disorders, psoriasis; for wound healing
10/01/2002US6458026 Transfection complex comprising a first component comprising one or more lipids, a second component comprising an oligolysine linked via a peptide bond to an integrin-binding peptide, and a third component comprising a nucleic acid
10/01/2002CA2281895C Ikb kinases
10/01/2002CA2255826C Mutated nonactivating igg2 domains and anti-cd3 antibodies incorporating the same
10/01/2002CA2220461C Therapeutic compounds comprised of anti-fc receptor antibodies
10/01/2002CA2168459C Fusion proteins containing the c-terminal of tetanus toxin linked to a heterologous protein
10/01/2002CA2168010C Tag reagent and assay method
10/01/2002CA2124087C Combinatorial strategies for polymer synthesis
10/01/2002CA2119930C Production of chimeric antibodies - a combinatorial approach