Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
01/2003
01/07/2003US6504007 GDNF receptor
01/07/2003US6503888 AAV-mediated delivery of DNA to cells of the nervous system
01/07/2003US6503887 Peroral gene therapy of diabetes and obesity
01/07/2003US6503886 Gene delivery; polypeptide conjugated to fibroblast growth factor fused to nucleic acid
01/07/2003US6503881 Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
01/07/2003US6503756 Antisense modulation of syntaxin 4 interacting protein expression
01/07/2003US6503755 Particle transfection: rapid and efficient transfer of polynucleotide molecules into cells
01/07/2003US6503754 Antisense modulation of BH3 interacting domain death agonist expression
01/07/2003US6503752 Lymphotropic agents and vectors
01/07/2003US6503749 Yeast strains possessing the interrupted ATF2 gene and their applications
01/07/2003US6503748 Endogenous ketogulonigenium plasmid
01/07/2003US6503747 Serotype-specific probes for Listeria monocytogenes
01/07/2003US6503744 Prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an alpha 2,3- and an alpha 2,8-activity. A beta 1,4-GalNAc transferase and a beta 1,3-galactosyltransferase, gene expression vectors and cells
01/07/2003US6503742 Ubiquitin ligases and uses related thereto
01/07/2003US6503741 Polyketide synthase genes from Streptomyces venezuelae
01/07/2003US6503738 Method of plasmid DNA production and purification
01/07/2003US6503737 Isolated nucleic acids relating to the fkbA gene within the FK-520 polyketide synthase gene cluster
01/07/2003US6503736 Antibodies to crosslinkers and methods for using the same
01/07/2003US6503735 Polynucleotides encoding chemokine β-15
01/07/2003US6503733 Polynucleotides which identify and encode NANCH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NANCH and a method for producing NANCH. Agonists, antibodies
01/07/2003US6503732 An infectious modified Tobacco Mosaic Virus (TMV) virion comprising a coat protein (CP) or a movement protein (MP) gene is replaced with a nuclear inclusion protease (NIa) expression cassette for the expression of a heterologous
01/07/2003US6503728 A nucleic acid comprising a nucleic acid sequence encoding pantropic hNT3 or hNGF having an alanine residue substituted at a position corresponding to D15 in hNT3 or D16 in hNGF, wherein the alanine substitution imparts trkB-binding such
01/07/2003US6503722 Diagnostic tests and kits for Clostridium difficile
01/07/2003US6503721 High-throughput assay for detection of ligand that binds preferential target sequences; obtain ligands, incubate with nucleotide sequences, monitor conformational adjustments, recover ligand that cause conformational adjustments
01/07/2003US6503720 Method for quantification of an analyte
01/07/2003US6503717 Detecting gene asociated with preferential phenotype; obtain preferential nucleotide sequences, transduce cells, culture cells, recover cell of preferential phenotype, monitor gene expression in recovered cells
01/07/2003US6503716 Compositions and methods for extracting a nucleic acid
01/07/2003US6503715 Solid support to which one or more specific Nucleic acid ligands is attached in a spatially defined manner. Each Nucleic acid ligand binds specifically and avidly to a particular Target molecule contained within a Test mixture,
01/07/2003US6503714 Method of detecting a substance to be analyzed
01/07/2003US6503713 Methods for identifying RNA binding compounds
01/07/2003US6503712 Methods and compositions for preparing a genomic library for knockout targeting vectors
01/07/2003US6503709 Detection the presence of an antibiotic resistant mecA gene in a biological sample, comprising the general steps of (a) treating cells contained within a biological sample to expose target single- stranded nucleic acid molecules; (b) reacting
01/07/2003US6503706 The invention addresses DNA-protein-complexes, proteins, DNA sequences and antibodies that are suitable for the detection of cells with an unlimited proliferation and tumor-formation potential. The invention further addresses methods for
01/07/2003US6503704 Method, reagent and kit for genotyping human papilloma virus
01/07/2003US6503703 Identification of host cell proteins that interact with viral proteins required for virus replication, and high throughput assays to identify compounds that interfere with the specific interaction between the viral and host cell protein.
01/07/2003US6503533 Antisense ogligonucleotides against Hepatitis B viral replication
01/07/2003US6503514 Attenuated strains of mycobacteria
01/07/2003US6503513 Diagnostics and therapy of diseases associated with HHV-8 infections
01/07/2003US6503511 Derivatives of choline binding proteins for vaccines
01/07/2003US6503508 Detergents
01/07/2003US6503504 In vitro cell growth to form tissue containing at least partially foreign DNA sequence which mediates production of the bioactive compound; implanting mass into an organism; treating diseases
01/07/2003US6503501 Targetable vector particles
01/07/2003US6503499 Viral particle comprising gene of interest operably linked to a promoter and envelope protein affixed with bifunctional adapter and a biotin molecule; internalizing into target cell for transduction and gene expression
01/07/2003US6503498 Apolipoprotein A-1 adenovirus vector compositions and methods
01/07/2003US6503452 Biosensor arrays and methods
01/07/2003CA2415199A1 Genes and their genetic products pertinent to microsatellite instable (msi+) tumours
01/07/2003CA2239753C Novel semaphorin z and gene encoding the same
01/07/2003CA2220923C Process of high purity albumin production
01/07/2003CA2190373C Yeast strains
01/07/2003CA2182398C Nucleic acid transfection efficiency increase by use of isopropanol in aqueous solutions
01/07/2003CA2113363C Process for constructing a cdna library and a novel polypeptide and dna coding the same
01/07/2003CA2104598C Methods for selection of recombinant host cells expressing high levels of a desired protein
01/07/2003CA2100167C Description process of the antibody (ab) repertoires and of the t-cell receptors (tcr) of an individual's immune system
01/07/2003CA2089666C Oligonucleotides for modulating the effects of cytomegalovirus infections
01/07/2003CA2059657C Process for the detection of a nucleotidic sequence by use of the sandwich hybridation technique
01/07/2003CA1341415C Targeted multifunctional proteins
01/06/2003CA2392549A1 Acetyl-coa carboxylase subunits
01/04/2003CA2351156A1 A bioprocess for the generation of pluripotent cell derived cells and tissues
01/03/2003WO2003001249A2 Modulating photoreactivity in a cell
01/03/2003WO2003001212A2 A method for diagnosing a person having multiple sclerosis
01/03/2003WO2003001178A2 Configurable dynamic three dimensional array
01/03/2003WO2003000941A2 Polypeptides having cellobiohydrolase i activity and polynucleotides encoding same
01/03/2003WO2003000933A1 Dual resonance energy transfer nucleic acid probes
01/03/2003WO2003000930A2 Nucleotide sequences involved in plant disease resistance
01/03/2003WO2003000928A2 Methods for identification of cancer cell surface molecules and cancer specific promoters, and therapeutic uses thereof
01/03/2003WO2003000927A2 Method for the determination of telomere length
01/03/2003WO2003000923A2 Maternal effect gametophyte regulatory polynucleotide
01/03/2003WO2003000922A2 Chimeric immunomodulatory compounds and methods of using the same
01/03/2003WO2003000919A2 Method for detecting diseases caused by chromosomal imbalances
01/03/2003WO2003000916A2 Telomerase expression repressor proteins and methods of using the same
01/03/2003WO2003000909A2 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes
01/03/2003WO2003000908A1 A method for introducing a nucleic acid into a eukaryotic cell
01/03/2003WO2003000907A2 Improved transfection of eukaryotic cells with linear polynucleotides by electroporation
01/03/2003WO2003000906A2 Plant disease resistance genes
01/03/2003WO2003000905A2 Identification and characterization of plant genes
01/03/2003WO2003000904A2 Identification and characterization of plant genes
01/03/2003WO2003000903A2 Regulation of human nek-like serine/threonine protein kinase
01/03/2003WO2003000902A1 Aphidicolin biosynthase cluster
01/03/2003WO2003000900A1 White spot syndrome virus vaccine
01/03/2003WO2003000899A1 MUTANT FORMS OF EtxB AND CtxB AND THEIR USE AS CARRIERS
01/03/2003WO2003000898A1 Plant genes involved in defense against pathogens
01/03/2003WO2003000897A2 Identification and characterization of phosphate transporter genes
01/03/2003WO2003000896A2 POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNα-5 GENE
01/03/2003WO2003000895A1 Yeast transformation vector system comprising multicopy paromomycin-resistance gene
01/03/2003WO2003000894A1 Polynucleotide vaccine
01/03/2003WO2003000893A2 Nucleic acids encoding g protein-coupled receptors
01/03/2003WO2003000891A2 Protein-protein interactions in the inner ear
01/03/2003WO2003000889A2 Identification of ses-1 and the uses of the same
01/03/2003WO2003000888A2 Method for separating bacterial cells and cell components
01/03/2003WO2003000887A1 Polynucleotide probe and primer originating in hepatitis e virus of japanese, chips having the same, kits having the same and method of detecting hepatitis e virus using the same
01/03/2003WO2003000886A1 Novel g protein-coupled receptor protein and dna thereof
01/03/2003WO2003000885A1 Process for constructing mutant
01/03/2003WO2003000882A2 Transgenic models for glucose homeostasis comrpising human gsk-3
01/03/2003WO2003000881A2 Method of plasmid stabilisation by in vivo deleting the antibiotic resistence and selecting with an essential gene
01/03/2003WO2003000880A2 Homoaconitase as a target for fungicides
01/03/2003WO2003000879A2 Novel promoters inducible by dna damaging conditions or agents and uses thereof
01/03/2003WO2003000878A2 Use of fkbp chaperones as expression tool
01/03/2003WO2003000877A2 A soluble complex comprising a retroviral surface glycoprotein
01/03/2003WO2003000874A2 Regulation of human serine/threonine protein kinase nek3
01/03/2003WO2003000872A1 Production of infectious hepadnavirus particles containing foamy retrovirus envelope proteins and methods of using the same