Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
07/2003
07/31/2003US20030144183 Synthetic glycosulfopeptides and methods of synthesis thereof
07/31/2003US20030144182 CD40-Ligand lacking native-pattern glycosylation
07/31/2003US20030144180 Contains as active ingredient a therapeutically effective amount of agent for either enhancing protein kinase c production and/or activation
07/31/2003US20030144176 Methods and compositions relating to MEK5 and cardiac hypertrophy and dilated cardiomyopathy
07/31/2003US20030144165 For use in detergents and in baking
07/31/2003US20030143745 Vector with an origin of replication, a counterselectable marker and a selectable marker that is exciseable by crossover for the unicellular host
07/31/2003US20030143744 Method for the production of cotton somatic embryos
07/31/2003US20030143743 Non-viral transfection of dendritic cells correlated with effective loading of tumor antigens
07/31/2003US20030143742 Compositions for receptor/liposome mediated transfection and methods of using same
07/31/2003US20030143741 Rolling circle replicon expression vector
07/31/2003US20030143740 Integrating nucleic acid into the genome of mammalian cells by forming an integrator complex between a nucleic acid containing a transposon and a transposase specific for the transposon
07/31/2003US20030143738 Compositions and methods for treating ischemic stroke
07/31/2003US20030143737 Long-term cell-culture compositions and genetically modified animals derived therefrom
07/31/2003US20030143735 Contacting human vpr interacting protein with a test compound and comparing the affinity of the vpr in the presence and absence of it
07/31/2003US20030143732 RNA interference mediated inhibition of adenosine A1 receptor (ADORA1) gene expression using short interfering RNA
07/31/2003US20030143730 The viral DNA is introduced into a culture of encapsidation cells and the viruses produced are harvested following release into the supernatant such as by ultrafiltration; use of iodixanol for purification of adenoviruses
07/31/2003US20030143729 Also animal models; use determining substrate binding, detecting expression, drug screening, and treatments for diseases or conditions related to 4-aminobutyric acid (GABA) or taurine transporters
07/31/2003US20030143725 Microarray fabrication techniques and apparatus
07/31/2003US20030143723 For performing nucleic acid amplification on a plurality of biological samples
07/31/2003US20030143715 Glutaryl cephalosporin amidase from pseudomonas diminuta BS-203
07/31/2003US20030143711 Hydrolyses organophosphate insecticides including malathion; bioremediation
07/31/2003US20030143710 Protein corresponding to recombinant fungal epoxide hydrolase; use making enantiomerically pure diols and/or epoxides
07/31/2003US20030143709 Used to control expression of a transgene, detect glucuronides in a sample, and isolate glucuronides from a sample
07/31/2003US20030143708 Method and reagent for the treatment of alzheimer's disease
07/31/2003US20030143707 Proteins having DNA repair promoting activity
07/31/2003US20030143706 Novel human leucine-rich repeat containing protein expressed predominately in bone marrow, HLRRBM1
07/31/2003US20030143703 Recombinant microorganism expressing polyhydroxyalkanoate biosynthesis enzyme and intracellular PHA depolymerase
07/31/2003US20030143700 Specific, asymmetric reduction of 3-quinuclidinone using tropinone reductase-I in the presence of a reduced coenzyme to produce (R)-3-quinuclidinol; high optical purity
07/31/2003US20030143697 Nucleic acid encoding a fusion polypeptide that forms a multimer that binds to a cytokine to form a nonfunctional complex; cytokine antagonists for the treatment of cytokine-related diseases or disorders
07/31/2003US20030143695 Novel polypeptide and dna thereof
07/31/2003US20030143693 Growing, under suitable conditions, procaryotic or eucaryotic host cells transformed or transfected with a specific DNA, and isolating the desired polypeptide product of the expression of such DNA sequence
07/31/2003US20030143692 Methods and compositions for modulating integrin-mediated cell-cell interactions
07/31/2003US20030143690 Peptides and proteins that effect protein phosphorylation; genetic engineered DNA; useful for therapy and diagnosis
07/31/2003US20030143689 Peptides and proteins that effect ligand transport encoded by a specific nucleic acid, useful in development of human therapeutics and diagonstic formulations and procedures
07/31/2003US20030143687 Biologic variability of asthma associated factors useful in treating and diagnosing atopic allergies including asthma and related disorders
07/31/2003US20030143685 Nucleic acid expression control sequence cassettes comprising a stable bacteriophage T5 promoter and nucleic acid regulatory sequences, useful for generating stable expressin vectors of high-level protein expression; culture product
07/31/2003US20030143684 Combining a compound to be tested, a host cell expressing a recombinant protein containing a mammalian C-C chemokine receptor 3 and a ligand for binding of ligand to such receptor, detecting the formation of a receptor-ligand complex
07/31/2003US20030143683 Introducing a nucleotide sequence encoding prefered amino acid sequences in into a host cell and culturing the host cell in which the peptides are expressed from the nucleotide sequence; human therapeutics and diagnostic protein
07/31/2003US20030143682 Substituting an amino acid within the variable domain of the heavy or light chain of the monoclonal antibody wherein above amino acid containing a nonpolar side chain, with a proline
07/31/2003US20030143681 Diagnose and treat neurological conditions
07/31/2003US20030143680 Bacterial cells lacking deformylase and/or transformylase
07/31/2003US20030143679 Genes encoding insect odorant receptors and uses thereof
07/31/2003US20030143677 Activated rec-D-hydantoinases
07/31/2003US20030143676 Receptor polypeptides and polynucleotides encoding such polypeptides; for treating a disorder characterized by an elevated level of osteopontin
07/31/2003US20030143674 Polypeptides fused to heterologous polypeptide sequences, and an antibodies which bind to the above polypeptides
07/31/2003US20030143672 Providing conservative or semi-conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes, useful in eliciting immune responses with respect to corresponding wildtype epitopes
07/31/2003US20030143671 Anti-microbial polypeptides can be sequence-defined by conserved cysteine residue patterns and are termed defensins; anti-idiotypic antibody of an antibody which specifically binds to above polypeptide or protein
07/31/2003US20030143670 Identification of three peptide agonists for the orphan GPCR( G-protein coupled receptor) designated SNORF44
07/31/2003US20030143668 Guanosine triphosphate-binding protein coupled receptors
07/31/2003US20030143667 Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions
07/31/2003US20030143666 Genetic locus for everninomicin biosynthesis
07/31/2003US20030143665 Calcium independent receptor of alpha-latrotoxin,characterization and uses thereof
07/31/2003US20030143660 Genes have been isolated from Rhodococcus and Deinococcus which encode a specific lycopene beta -cyclase capable of converting acyclic carotenoids with atleast one psi-end group to corresponding asymetric caratenoid
07/31/2003US20030143656 Drug screening compounds which inhibit rate of phosphorylation by kinase having hydrophobic pocket domain; surface plasmon resonance; fusion proteins; anticancer-/ antidiabetic agents
07/31/2003US20030143654 Which participates in the ubiquitin-dependent proteolytic pathway that targets regulatory proteins for rapid intracellular degradation
07/31/2003US20030143626 Such as cyclin-dependent kinases and/or bax genes/proteins covalently linked to platform compound (thioredoxin); drug screening
07/31/2003US20030143623 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
07/31/2003US20030143622 Human RNA binding proteins
07/31/2003US20030143621 Contacting a cellular component with a reagent which binds to PC-1 (prostate cancer-1) protein
07/31/2003US20030143620 Carbohydrate ligands specific for MHC molecules
07/31/2003US20030143619 Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders
07/31/2003US20030143618 PCR amplification of each part of the two parts of DNA molecule by means of two primer sets that build in a recombiantion site at the outer end of each PCR product, ligation of PCR product, recombiantion cloning of the PCR
07/31/2003US20030143616 Addressable protein arrays
07/31/2003US20030143614 Easier preparation of probes without attaching them to a fixed support, allow the use of larger number and differnt types of probes, improve hybridization and enzymatic kinetics relatie to solid-phase hybridization
07/31/2003US20030143613 Protein expression profiling
07/31/2003US20030143611 Cloning the DNA sequence encoding recombinant SRTA-70 proteins
07/31/2003US20030143609 Method of identifying a gene product
07/31/2003US20030143606 Nucleic acid comprising sequence segment of chemically pretreated DNA
07/31/2003US20030143605 Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations
07/31/2003US20030143602 Useful as probes and primers for amplification and sequencing; fluorescent labeling
07/31/2003US20030143599 Attaching a primer; ligation of an adaptor sequence or homopolymeric tailing with terminal deoxynucleotidyltransferase
07/31/2003US20030143598 Bioconjugate-nanoparticle probes
07/31/2003US20030143597 Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis
07/31/2003US20030143595 Isolated and/or recombinantly produced polypeptide; use in regulating spermatogenesis, cell differentiation and proliferation
07/31/2003US20030143589 Drug metabolizing enzymes
07/31/2003US20030143588 Phosphodiesterases
07/31/2003US20030143586 Genetic hypermutability of plants for gene discovery and diagnosis
07/31/2003US20030143583 Novel response element
07/31/2003US20030143582 Polypeptides useful for regulating the cell cycle, proliferation, tumorigenesis, and genomic stability, mutants of such polypeptide useful in detecting abnormal cells and diagnosing diseases
07/31/2003US20030143578 Stably transfecting a population of cells with a gene- trap vector, identifying cells with a trapped gene, distributing sorted cells into matrix format, pooling cells from matrix into discrete pools, producing cDNA sequence tag
07/31/2003US20030143577 High fidelity DNA polymerase compositions and uses therefor
07/31/2003US20030143576 Method and device for integrated protein expression, purification and detection
07/31/2003US20030143574 Method for analysing the length of a nucleic acid molecule
07/31/2003US20030143572 Based upon the particular patient's genotype. A PCR kit and/or a gene chip detects multiple genes, expressions and/or mutations associated with a particular cancer using a sample of patient's tissue or blood, a detector and a computer
07/31/2003US20030143570 A solid support comprising immobilized latent thiol groups, activating the thiol groups and reacting activated thiol groups with an affinity ligand having atleast an alpha-beta unsaturated carbonyl group, immobizing ligand on the support
07/31/2003US20030143569 Methods of immobilizing ligands on solid supports and apparatus and methods of use therefor
07/31/2003US20030143567 An expression vector containing a promoter operably linked to a nucleic acid that encodes a prokaryotic enzyme having both epimerase/ reductase activity catalyzes conversion of GDP-4-keto-6-deoxymannose to GDP-fucose
07/31/2003US20030143566 Receptacle for withdrawl of blood containing a solution for stabilizing nucleic acids, and a solid phase capable of binding nucleic acid such as, guanidinium thiocyanate, a detergent, a reducing agent and a buffer
07/31/2003US20030143562 Structurally biased random peptide libraries based on different scaffolds
07/31/2003US20030143561 Nucleoside derivatives for library preparation
07/31/2003US20030143559 A modified estrogen receptor alpha ligand binding domain containing an amino acid modification in region 1, at region 2, or atleast one amino acid modifiation in both of regions, and these domain interacts with a nonendogenous ligand
07/31/2003US20030143558 Methods for attenuation of virulence in bacteria
07/31/2003US20030143557 Useful in identifying molecules, that bind TRPM4b (transmembrane channel polypeptides) which modulate TRPM4b ion channel activity, and/or which alter expression of TRPM4b within cells
07/31/2003US20030143553 Nucleic acid amplification with direct sequencing
07/31/2003US20030143541 Isolated nucleic acid molecule encoding a polypeptide that mediates a detectable physiological or behvioral effect in mammals
07/31/2003US20030143539 Polynucleotide sequences or subsequences library that are underexpressed or overexpressed in tumor cells
07/31/2003US20030143536 Mixing a set of primers with a target sample; incubating the primer-target sample mixture to hybridize; mixing DNA polymerase with the primer-target sample mixture; incubating the polymerase- target sample mixture to promote replication
07/31/2003US20030143532 Method for producing biochemical analysis data and apparatus used therefor
07/31/2003US20030143531 Detection and quantification of microorganisms using amplification and restriction enzyme analysis
07/31/2003US20030143530 Method for the detection of influenza a/b viruses