Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/2003
08/28/2003WO2003070987A1 Nucleotide sequence coding for a tolc containing a heterologous amino acid sequence
08/28/2003WO2003070985A1 Compositions and methods for evaluating viral receptor/co-receptor usage and inhibitors of virus entry using recombinant virus assays
08/28/2003WO2003070984A1 Methods and reagents for detecting target binding by nucleic acid ligands
08/28/2003WO2003070983A1 RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN KINASE C ALPHA (PKC-ALPHA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070982A1 Complex comprising at least two biospecific elements separated by a nucleic acid linker e.g. for identification of drug delivery candidates. combinatorial library of such complexes
08/28/2003WO2003070981A2 Seequences specifically deleted mycobacterium tuberculosis genome and their use in diagnostics and as vaccines
08/28/2003WO2003070980A2 Nucleic acid quantification
08/28/2003WO2003070974A2 Mismatch repair detection
08/28/2003WO2003070972A2 RNA INTERFERENCE MEDIATED INHIBITION OF CHROMOSOME TRANSLOCATION GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070970A2 RNA INTERFERENCE MEDIATED INHIBITION OF NF-KAPPA B/REL-A GENE EXPRESSION USING SHORT INTERFEREING NUCLEIC ACID (siNA)
08/28/2003WO2003070969A2 RNA INTERFERENCE MEDIATED INHIBITION OF BCL2 GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070968A2 RNA INTERFERENCE MEDIATED INHIBITION OF GASTRIC INHIBITORY POLYPEPTIDE (GIP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070967A2 Highly homogeneous molecular markers for electrophoresis
08/28/2003WO2003070966A2 RNA INTERFERENCE MEDIATED TARGET DISCOVERY AND TARGET VALIDATION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070965A2 The eaat2 promoter and uses thereof
08/28/2003WO2003070963A2 Improved protein expression in bacillus subtilis
08/28/2003WO2003070959A2 Process for producing levodione
08/28/2003WO2003070958A1 Retroviral gene therapy vectors including insulator elements to provide high levels of gene expression
08/28/2003WO2003070957A2 Plant polypeptide production
08/28/2003WO2003070956A1 Expression cloning methods in filamentous fungi
08/28/2003WO2003070955A1 CONSTRUCTION OF NOVEL STRAINS CONTAINING MINIMIZING GENOME BY Tn5-COUPLED Cre/loxp EXCISION SYSTEM
08/28/2003WO2003070954A1 Transcriptional factor, transcriptional factor gene, recombinant vector containing transcriptional factor gene, koji-mold transformed by the vector and method of using koji-mold
08/28/2003WO2003070953A1 Novel compound for inhibiting serine proteases and for inhibiting viral infections or viral propagation: rld 8564
08/28/2003WO2003070952A1 Fluorescent protein
08/28/2003WO2003070951A1 Arteriosclerosis-specific gene and utilization thereof
08/28/2003WO2003070950A1 Novel dna and use thereof
08/28/2003WO2003070949A1 Cat immunisation vectors
08/28/2003WO2003070948A1 Cloning of the human kinase suppressor of ras-1 (ksr-1)
08/28/2003WO2003070945A1 Method to isolate dna
08/28/2003WO2003070944A1 Method of separation using aromatic thioether ligands
08/28/2003WO2003070943A1 Methods for two-dimensional conformation-dependent separation of non-circular nucleic acids
08/28/2003WO2003070942A1 Method for coarse purification of cell digests from microorganisms
08/28/2003WO2003070941A2 Method for the identification of tissue-specific regulatory sequences
08/28/2003WO2003070939A1 Dna fragment having promoter activity
08/28/2003WO2003070938A1 Gene expression data analyzer, and method, program and recording medium for gene expression data analysis
08/28/2003WO2003070937A1 Protein having osteogenic protein-binding region and gene encoding the same
08/28/2003WO2003070934A1 METHOD OF JUDGING GENOTYPE OF REGION AROUND PLANT sd-1 GENE AND METHOD OF EXAMINING SEMI-DWARF CHARACTERISTIC OF PLANT USING THE JUDGMENT METHOD
08/28/2003WO2003070933A2 Process of cell electrofusion
08/28/2003WO2003070932A1 Polynucleotide for target gene
08/28/2003WO2003070931A2 Methods for conducting site-specific dna recombination
08/28/2003WO2003070927A1 Regulation of human gtpase
08/28/2003WO2003070925A2 Identification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity
08/28/2003WO2003070918A2 Rna interference by modified short interfering nucleic acid
08/28/2003WO2003070917A2 Rna interference mediated inhibition of myc and myb genes or genes of their respective pathways
08/28/2003WO2003070916A2 Dna encoding snorf44 receptor
08/28/2003WO2003070915A2 Mutated constitutively active nuclear orphan receptor
08/28/2003WO2003070914A2 RNA INTERFERENCE MEDIATED INHIBITION OF FOS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070912A2 RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070911A2 Rna interference mediated inhibition of type 1 insulin-like growth factor receptor (igf-1r)
08/28/2003WO2003070910A2 INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AND VEGF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070908A2 Novel spinosyn-producing polyketide synthases
08/28/2003WO2003070907A2 Novel fungal lipase
08/28/2003WO2003070906A2 Cellular genes regulated by hiv-1 infection and methods of use thereof
08/28/2003WO2003070905A2 Electroporation methods for introducing bioactive agents into cells
08/28/2003WO2003070904A2 Human rnase iii and compositions and uses thereof
08/28/2003WO2003070903A2 RNA INTERFERENCE MEDIATED INHIBITION OF GRB2-ASSOCIATED BINDING PROTEIN 2 (GAB2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070902A2 Receptors and membrane-associated proteins
08/28/2003WO2003070901A2 Heat stable mutants of starch biosynthesis enzymes
08/28/2003WO2003070898A2 Selective extraction of dna from groups of cells
08/28/2003WO2003070897A2 RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR SUPERFAMILY GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070896A2 RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070895A2 RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070894A2 A non-invasive diagnostic test utilizing histone modification markers
08/28/2003WO2003070888A2 Rna interference mediated inhibition of checkpoint kinase-1 (chk-1) gene expression using short interfering nucleic acid
08/28/2003WO2003070887A2 RNA INTERFERENCE MEDIATED INHIBITION OF POLYCOMB GROUP PROTEIN EZH2 GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070886A2 Inhibition of protein tyrosine phosphatase type iva expression byshort interfering nucleic acid
08/28/2003WO2003070885A2 SHORT INTERFERING NUCLEIC ACID INHIBITION OF STEAROYL-CoA DESATURASE (SCD) GENE
08/28/2003WO2003070884A2 RNA INTERFERENCE MEDIATED INHIBITION OF MDR P-GLYCOPROTEIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070883A2 Methods and compositions for treating aids and hiv-related disorders using 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, or 2045 molecules.
08/28/2003WO2003070882A2 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and used thereof
08/28/2003WO2003070881A2 RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYPROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070880A2 Bacteria with reduced genome
08/28/2003WO2003070878A2 Antisense modulation of hematopoietic cell protein tyrosine kinase expression
08/28/2003WO2003070876A2 Method for attaching nucleic acid molecules to electrically conductive surfaces
08/28/2003WO2003070875A2 Container with at least one electrode
08/28/2003WO2003070771A1 Rrp sequences and knockout mice and uses thereof
08/28/2003WO2003070770A2 Engineered human kunitz-type protease inhibitor
08/28/2003WO2003070769A2 Organic compounds having anti-angiogenic activity
08/28/2003WO2003070768A2 Cd40 splice variants,method of detection thereof, compositions comprising said variant(s) or nucleic acid encoding the same and use thereof
08/28/2003WO2003070767A1 Tissue specific expression
08/28/2003WO2003070766A2 A transducer of mas signalling
08/28/2003WO2003070765A2 Growth hormone fusion protein
08/28/2003WO2003070763A1 Methods and compositions for treating metabolic bone diseases relating to human endokine alpha
08/28/2003WO2003070760A2 Anti-amyloid beta antibodies and their use
08/28/2003WO2003070757A1 Nucleic acid encoding an herv-h polypeptide for diagnosing colorectal cancer
08/28/2003WO2003070752A2 Mhc-peptide complex binding ligands
08/28/2003WO2003070750A2 Rna interference mediated inhibition of hepatitis c virus
08/28/2003WO2003070748A2 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
08/28/2003WO2003070747A2 Insulin and igf-1 receptor agonists and antagonists
08/28/2003WO2003070744A1 RNA INTERFERENCE MEDIATED INHIBITION OF INTERLEUKIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070743A1 RNA INTERFERENCE MEDIATED INHIBITION OF G72 AND D-AMINO ACID OXIDASE (DAAO) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070742A1 RNA INTERFERENCE MEDIATED INHIBITION OF TELOMERASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070740A1 RIBOZYMES WITH BROAD tRNA AMINOACYLATION ACTIVITY
08/28/2003WO2003070735A2 Components for producing amphoteric liposomes
08/28/2003WO2003070283A2 Agent for inhibiting development or progress of proliferative diseases and especially cancer diseases and pharmaceutical composition containing said agent
08/28/2003WO2003070271A2 Novel complexes for inducing an immune response
08/28/2003WO2003070268A1 Remedy for infections
08/28/2003WO2003070256A1 Hyaluronic acid mediated adenoviral transduction
08/28/2003WO2003070230A1 Use of agents that modulate pde11a activity
08/28/2003WO2003070229A2 Use of proteinase inhibitors in the treatment of autoimmune diseases