Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
10/2003
10/09/2003US20030190706 Novel promoters and gene expression method by using the promoters
10/09/2003US20030190705 Method of humanizing immune system molecules
10/09/2003US20030190700 Modified DNA molecule with a nucleotide sequence which is 80% but less than 100% homologous to desired trait DNA molecules and which imparts the desired trait to plants transformed with the DNA construct
10/09/2003US20030190697 With advantages such as ability of the polypeptides to preferentially bind a CD28/CTLA-4 receptor at a level greater or less than the ability of human B7-1, inhibit altered level of T cell proliferation response greater than human B7-1
10/09/2003US20030190696 Vertebrate tissue pattern-inducing proteins, and uses related thereto
10/09/2003US20030190693 Identifying inhibitors and activators of eukaryotic potassium channels
10/09/2003US20030190687 Interacts with human DR5 to produce agonistic or antagonistic effects including inhibition of cell proliferation and apoptosis; used to treat apoptosis-related disease and unregulated cell growth
10/09/2003US20030190683 Minicell-based rational drug design
10/09/2003US20030190679 Used to treat apoptotic disorder like cancer, autoimmune disorder, viral infections, Alzheimer's disease, Parkinson's disease or aplastic anemia; treats inflammatory disorders like arthritis, Crohn's disease, psoriasis, allergy or asthma
10/09/2003US20030190677 Obtaining a consensus protein from a group of amino acid sequences of a defined protein family
10/09/2003US20030190674 Production of anti-self antibodies from antibody segment repertoires and displayed on phage
10/09/2003US20030190672 Novel phosphodiesterase and genes thereof
10/09/2003US20030190666 Involves nucleic acids extracted from nematode or arthropod pests which encode P- glycoprotein homologs and regulate resistance to the macrocyclic lactones; enhancing the efficacy of the lactones using multidrug resistant reversing agents
10/09/2003US20030190664 Pharmacogenomics and idenitfication of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions
10/09/2003US20030190663 Novel assay for nucleic acid analysis
10/09/2003US20030190662 Nucleic acid marker ladder for estimating mass
10/09/2003US20030190661 Fluorescently labeling nucleic acid molecules during nucleic acid synthesis using multi-subunit reverse transcriptases (RT) such as Avian Sarcoma- Leukosis Virus RT
10/09/2003US20030190660 Compositions and methods for detecting and quantifying gene expression
10/09/2003US20030190659 Oligomers that hybridize to Inhibition of Apoptosis (IAP) polynucleotides and methods for using them to enhance apoptosis and treat proliferative diseases
10/09/2003US20030190656 Prognosticating metastasis in a breast cancer patient by identifying differential modulation of each gene selected from a group; gene expression portfolios and kits
10/09/2003US20030190655 Involves genetically marked organisms, a database server, a method for assigning sequences to genetically mark organisms and for book keeping data pertaining to the marked organisms and/or their owner, producer or source
10/09/2003US20030190654 Double-stranded RNA (dsRNA) and method of use for inhibiting expression of a fusion gene
10/09/2003US20030190651 Preventing, ameliorating, correcting dysfunctions or diseases such as cancer, peripheral and central nervous system diseases, and chronic obstructive pulmonary disease
10/09/2003US20030190648 Involves extraction of a partial sequence corresponding to a target gene from a genome sequence by homology search on a database, prediction and extraction of common sequences from exon regions using plural programs, amplification
10/09/2003US20030190646 Methods for detecting target nucleic acids using coupled ligation and amplification
10/09/2003US20030190643 Sequencing by mass spectrometry
10/09/2003US20030190642 Thymus expressed human cytochrome p450(p450tec)
10/09/2003US20030190639 Diagnosis of Cryptogenetic inflammatory bowel diseases (IBDs)
10/09/2003US20030190638 Determination of telomere length and telomerase activity, ability to increase/decrease the activity in treatment of proliferative diseases; intracellular inhibition of telomerase activity; treatment of cancer and AIDS, muscular dystrophy
10/09/2003US20030190635 RNA interference mediated treatment of Alzheimer's disease using short interfering RNA
10/09/2003US20030190633 Support for fixing nucleotide and process for producing the same
10/09/2003US20030190632 By electronic control of the transport and attachment of specific binding entities to specific microlocations; concentrate analytes and reactants, remove non-specifically bound molecules, and improve detection of analytes
10/09/2003US20030190631 Predicting an increased risk of a human developing Alzheimer's disease by assaying for a mutation within the ADN sequence of the CP2/LSF/ LBP-1 gene
10/09/2003US20030190630 For production of lactic acid
10/09/2003US20030190629 Antisense modulation of PTTG1 expression
10/09/2003US20030190628 Beads, preparing method for the same, flow cytometer and program
10/09/2003US20030190626 Having increased nuclease resistance and binding affinity to a complementary strand of nucleic acid; useful for modulating expression of a protein in organisms, for diagnosis, therapy of conditions responsive to oligonucleotide therapeutics
10/09/2003US20030190618 For rapid identification of novel expressed transcripts at least 20 base pairs long
10/09/2003US20030190616 Differentially methylated sequences in pancreatic cancer
10/09/2003US20030190614 Non-human primate Fc receptors and methods of use
10/09/2003US20030190613 Polynucleotide encoding an activated human T-lymphocyte-derived protein related to ubiquitin conjugating enzyme
10/09/2003US20030190607 Polymorphisms in human pyruvate dehydrogenase E1 beta (PDH E1 beta) gene; for analysing allelic variation; bioinformatic applications
10/09/2003US20030190606 Hepatitis C virus NS5B truncated protein and methods thereof to identify antiviral compounds
10/09/2003US20030190605 Methods for rapid detection and identification of bioagents for environmental testing
10/09/2003US20030190604 Nucleic acid amplification method: ramification-extension amplification method (RAM)
10/09/2003US20030190601 Useful for diagnosis and therapy, research tools for drug discovery
10/09/2003US20030190598 Used as phage display library of variable heavy domain (VHH or VH) fragments (sdAb fragments)
10/09/2003US20030190597 For drug screening and development, exposing to a compound that paralyzes or kills nematoda
10/09/2003US20030190348 Cationic amphiphiles for intracellular delivery of therapeutic molecules and its composition, process and method of treatment
10/09/2003US20030190332 Engineered viral particle containing a group of co-expressed viral proteins or portions expressed in an edible plant material, adminstering such plant material containing viral vaccine to the gastrointenial mucosa of the patient
10/09/2003US20030190330 Recombinant canine distemper virus vaccine against canine distemper and leishmaniasis
10/09/2003US20030190329 Coxsackievirus vectors and their use in prevention and treatment of disease
10/09/2003US20030190324 Immunologically significant herpes simplex virus antigens and methods for using same
10/09/2003US20030190312 Microarray/immunoassay; for aging resistance; cytochromes; NADH oxidoreductases; lyases; cytochrome C oxidases; isomerases; GTPases
10/09/2003US20030190311 Immunoglobulins; fusion proteins; vaccines
10/09/2003US20030190285 Having nucleotide sequence of any one of the strands of any one of the members of the High Mobility Group protein genes or LIM protein genes, including modified versions and derivatives thereof; diagnostic and therapeutic applications
10/09/2003CA2762016A1 Methods for increasing polypeptide production
10/09/2003CA2519642A1 A composition and method for killing of tumours
10/09/2003CA2481376A1 Novel proteins and nucleic acids encoding same
10/09/2003CA2481232A1 Replikin peptides in rapid replication of glioma cells and in influenza epidemics
10/09/2003CA2480724A1 Expression of phospholipid:diacylglycerine acyltransferase (pdat) for the production of plant storage lipids with polyunsaturated fatty acids
10/09/2003CA2480694A1 Ox40r binding agents
10/09/2003CA2480682A1 Nucleic acid sequence and protein, and polypeptides encoding mannitol dehydrogenases or parts thereof, and their preparation and use in diagnostics and therapy
10/09/2003CA2480673A1 Methods and compositions for detection and quantitation of nucleic acid analytes
10/09/2003CA2480661A1 A method of modulating cellular activity
10/09/2003CA2480635A1 Cancer associated protein kinases and their uses
10/09/2003CA2480525A1 Single primer isothermal nucleic acid amplification-enhanced analyte detection and quantification
10/09/2003CA2480419A1 Antiopoietin-related growth factor
10/09/2003CA2480386A1 Novel galactose transferases, peptides thereof and nucleic acid encoding the same
10/09/2003CA2480372A1 Combination therapy using trefoil peptides
10/09/2003CA2480319A1 Chimeric delta endotoxin protein of cry1ea and cry1ca
10/09/2003CA2480286A1 Disruption of the redk gene
10/09/2003CA2480277A1 Ehanced protein expression in bacillus
10/09/2003CA2480164A1 Hybridization rate enhancement for substrate-bound specific nucleic acid-binding agents
10/09/2003CA2480160A1 Multiplex standardized reverse transcriptase-polymerase chain reaction method for assessment of gene expression in small biological samples
10/09/2003CA2480159A1 Secretion of proteins with multiple disulfide bonds in bacteria and uses thereof
10/09/2003CA2480138A1 Transcellular drug delivery system
10/09/2003CA2480018A1 The functional disruption of avian immunoglobulin genes
10/09/2003CA2479990A1 Method for the identification of microorganisms by means of in situ hybridization and flow cytometry
10/09/2003CA2479763A1 Potent oncolytic herpes simplex virus for cancer therapy
10/09/2003CA2479759A1 Protamine-adenoviral vector complexes and methods of use
10/09/2003CA2479750A1 Fibrinogen binding moieties
10/09/2003CA2479647A1 Human deubiquitinating protease gene on chromosome 7 and its murine ortholog
10/09/2003CA2479379A1 Methods and compositions for analysis of urine samples in the diagnosis and treatment of kidney diseases
10/09/2003CA2479028A1 Minimizing metal toxicity during electroporation enhanced delivery of polynucleotides
10/09/2003CA2469720A1 Truncated lysostaphin molecule with enhanced staphylolytic activity
10/09/2003CA2448540A1 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
10/08/2003EP1351183A2 Sequence data combining method, apparatus and program
10/08/2003EP1350855A2 Array based hybridization assays
10/08/2003EP1350854A1 Catalytic nucleic acid and its medical use
10/08/2003EP1350851A1 Method of detecting polymorphism in dna by using mass spectroscopy
10/08/2003EP1350850A2 Method for expressing foreign genes and vectors therefor
10/08/2003EP1350849A2 Method for cloning and expression of BsaI restriction endonuclease and Bsal methylase in E. coli
10/08/2003EP1350848A2 T-cell membrane protein (TIRC7), gene encoding it and antibodies against it and uses thereof
10/08/2003EP1350847A1 Human glioma antigen and process for preparing the same
10/08/2003EP1350845A1 Molecule correspondent to genotype and phenotype, composing elements thereof, method of producing the corespondent molecule and method of using the same
10/08/2003EP1350844A2 Xyloglucanase, polynucleotide encoding the enzyme, and method of preparing the enzyme
10/08/2003EP1350843A2 Alkaline cellulase variants
10/08/2003EP1350842A2 Production and use of an improved terminal deoxynucleotidyl transferase
10/08/2003EP1350841A2 Thermostable or thermoactive DNA polymerase with attenuated 3'-5' exonuclease activity