Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
01/2004
01/08/2004US20040005691 Comprises genetically engineered beta-site amyloid precursor protein-cleaving enzyme (BACE) for prevention, diagnosis and treatment of neurodegenerative and alzheimer's diseases
01/08/2004US20040005690 Modified CBD/RGD recombinant attachment factor for improving cell-attachment efficiency and the manufacturing method thereof
01/08/2004US20040005689 Three dimensional model of acute myeloid leukemia protein (AML-1) comprising runt domain for treating and preventing diseases associated with chromosomal translocations; genetic mapping
01/08/2004US20040005688 Comprises dishevelled associated kinase (DAK) protein for diagnosis, prevention and treatment of cell proliferative diseases
01/08/2004US20040005687 Kinase crystal structures
01/08/2004US20040005686 Crystalline structure of human MAPKAP kinase-2
01/08/2004US20040005683 Forms of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase
01/08/2004US20040005682 Biocidal protein
01/08/2004US20040005678 Introducing into host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate
01/08/2004US20040005677 Producing and extracting optically pure lactic acid for use in food processing, brewing, tanning and liquid crystals
01/08/2004US20040005673 System for manipulating nucleic acids
01/08/2004US20040005672 Heterologous production of polyketides
01/08/2004US20040005669 Multimeric polypeptide for treating diabetes
01/08/2004US20040005668 Production of human parathyroid hormone from microorganisms
01/08/2004US20040005667 Comprises protein for developing vaccines which prevent chlamydial infections; genetic vaccines
01/08/2004US20040005666 Methods and reagents for modulating cholesterol levels
01/08/2004US20040005665 Comprises nucleotide sequences coding membrane proteins for diagnosing, preventing and treating inflammatory, tumorous and nervous system disorders
01/08/2004US20040005663 Mixture comprising genetically engineered swine proteins for treating and preventing bone and skin disorders; bioreactors
01/08/2004US20040005662 Culuring transgenic cells which codes bactericides; genetic vaccines
01/08/2004US20040005660 Production of peptides and proteins by accumulation in plant endoplasmic reticulum-derived protein bodies
01/08/2004US20040005658 Embryonic protein for diagnosis, prevention and treatment of tumors, blood, viral and immunological disorders
01/08/2004US20040005655 Comprises nucleotides equences coding enzymatic polypeptides for destroying or detecting hydrogen peroxide and producing glyoxylic acid; bleaching; bactericide; papermaking
01/08/2004US20040005648 PYK2 related products and methods
01/08/2004US20040005643 Anti-human tenascin monoclonal antibody
01/08/2004US20040005639 Glycerylaldehyde-3-phosphate dehyrogenase promoter inducing cell death
01/08/2004US20040005638 Determining concentration of target antibodies in mixtures; food analysis; disease diagnosis
01/08/2004US20040005630 Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
01/08/2004US20040005629 Natural ligand of orphan G protein coupled receptor GPR86 and methods of use
01/08/2004US20040005621 Method of determining a chemotherapeutic regimen based on ERCC1 expression
01/08/2004US20040005619 Diagnosing osteoporosis and paget's diseases via identifying variable numbers of tandem repeats in allelic sequences coding parathyroid hormone related peptide (PTHrP)
01/08/2004US20040005616 Separating and extracting nucleotide sequences using polyethylene glycol and dextran
01/08/2004US20040005615 Amplification and overexpression of oncogenes
01/08/2004US20040005614 Labeling, fragmenting and immobilizing polynucleotides; genome analysis
01/08/2004US20040005605 Determining content ratio of genetic recombinant in a sample
01/08/2004US20040005604 Comprises nucleotide sequences coding enzymatic polypeptide for degumming oil and food processing; antisense therapy
01/08/2004US20040005601 Identifying modulators of quadruplex DNA activity; drug delivery; cancer diagnosis; antitumor agents
01/08/2004US20040005600 Designing expression vector for improved accumulation of plasmodium protein in transformed cells
01/08/2004US20040005599 Heat resistant polymerase with improved accuracy in replication and amplification
01/08/2004US20040005598 Comprises nucleotide sequences coding protein upregulated in metastatic prostate cancer (PUMPCn) for diagnosis and treatment of tumors; antiproliferative agents; anticarcinogenic agents
01/08/2004US20040005594 Identifying and characterizing modulators of nucleic acid processing enzymes; enzyme inhibitors
01/08/2004US20040005593 Novel method for delivery and intracellular synthesis of siRNA molecules
01/08/2004US20040005592 Materials and methods relating to therapy and diagnosis using targeting of cells that express DCAL-Hy polypeptides
01/08/2004US20040005591 Kit for generating recombinant expression vector for use as tool in gene transfer, genetic mapping and heterologous gene expression
01/08/2004US20040005589 Isomaltulose synthases, polynucleotides encoding them and uses therefor
01/08/2004US20040005588 Using DNA vaccines to treat and prevent insulin depentent diabetes mellitus
01/08/2004US20040005587 Protein activity screening of clones having DNA from uncultivated microorganisms
01/08/2004US20040005585 Polynucleotide sequence assay
01/08/2004US20040005583 Method for analysing nucleic acids
01/08/2004US20040005581 Comprises nucleotide sequences coding vanilloid receptor-like receptor (VR4) for diagnosing and treating pain, inflammation, neurodegeneration, cardiovascular, cancer and urogenital diseases; drug screening
01/08/2004US20040005579 Nucleic acids, proteins, and antibodies
01/08/2004US20040005576 Comprises polypeptides for diagnosing, prognosing and preventing cancer, nervous system, developmental and metabolic disorders
01/08/2004US20040005570 Oligonucleotides which control expression of geranylgeranyl diphosphate synthase for treating tumors, apoptosis aberrations and developmental disorders; gene expression inhibition; antisense therapy
01/08/2004US20040005569 Antisense modulation of NF-kappa-B p50 subunit expression
01/08/2004US20040005567 Antisense modulation of cyclin-dependent kinase 4 expression
01/08/2004US20040005565 Antisense modulation of livin expression
01/08/2004US20040005564 Methods of identifying synthetic transcriptonal and translational regulatory elements, and compositions relating to same
01/08/2004US20040005561 Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
01/08/2004US20040005560 Comprise polynucleotide for treating cancer and inflammatory disorders; antisense therapy; gene therapy
01/08/2004US20040005558 Proteins, polynucleotides ecoding them and methods of using the same
01/08/2004US20040005552 Using immunoassays to detecting homopolynucleotide sequences in sample
01/08/2004US20040005551 Circulating epstein-barr virus DNA in the serum or plasma of patients for the prediction and detection of epstein-barr virus associated cancers apart from head, neck and lymphoid malignancies
01/08/2004US20040005550 Methods and compositions useful for targeting activated vitronectin receptor alphavbeta3
01/08/2004US20040005547 Using nucleotide sequences primers and probes for diagnosing liver toxicity
01/08/2004US20040005546 Use of ribozymes in the detection of adventitious agents
01/08/2004US20040005545 Plasmid comprising heterologous viral gene sequences for diagnosis, prevention and treatment of respiratory system disorders; vaccine development; viricides
01/08/2004US20040005544 Comprise RNA viruses for diagnosis, prevention and treatment of repiratory system disorders; vaccine development; viricides; antisense therapy
01/08/2004US20040005543 Compositions and methods for binding agglomeration proteins
01/08/2004US20040005542 Respiratory syncytial virus vaccines expressing protective antigens from promotor- proximal genes
01/08/2004US20040005541 Hepatitis b virus dna polymerase and surface antigen variants and methods of using same
01/08/2004US20040005539 Comprises expression vector coding antibody domains and heterologous proteins for use as model in design of improved binding domains; enzyme inhibitors
01/08/2004US20040005353 Delivery system for antisense oligonucleotides involves a liposomal composition, comprising a liposome which consists essentially of neutral phospholipids and an antisense oligonucleotide that is entrapped in the liposome and is
01/08/2004US20040005333 Recombinant gene fusion encoding a human IgG1 heavy chain constant region and a single-chain variable fragment antibody of 1A4A1 monoclonal antibody is disclosed. The recombinant antibody of the present invention confers human immune
01/08/2004US20040005332 Application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-142. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native
01/08/2004US20040005330 Mutated HIV Tat
01/08/2004US20040005328 Novel antigens of B. catarrhalis are provided, together with their use in vaccines as well as methods of diagnosing and/or detection. Branhamella catarrhalis (also known as Moraxella catarrhalis) is a gram-negative aerobic bacterium that causes
01/08/2004US20040005325 Helicobacter felis vaccine
01/08/2004US20040005324 Identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV-binding ability, chimeric antibodies
01/08/2004US20040005323 Efficient method for generating human antibodies in particular which are specific to be RSV fusion protein which combines in vitro primary of human spleen cells and antigen boosting in SCID mice is taught. This method provides for very high human
01/08/2004US20040005322 Compositions and methods related to TIM-3, a Th1-specific cell surface molecule
01/08/2004US20040005316 Use of HMG fragments as anti-inflammatory agents
01/08/2004US20040005309 Targeted therapeutic proteins
01/08/2004US20040005296 Gene therapy targeted to ischemic tissues.
01/08/2004US20040005293 High capacity recombinant adenoviral vector for treatment of hemophilia A
01/08/2004US20040005292 Antisense modulation of SMRT expression
01/08/2004US20040005276 Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with porphyromonas gingivalis
01/08/2004DE10228081A1 Verfahren zum Nachweis einer gesteigerten Tumorsuszeptibilität A method for detecting an increased tumor susceptibility
01/08/2004DE10226675A1 Verfahren zur Testung des hormonellen Effekts von Substanzen Method for testing the hormonal effect of substances
01/08/2004DE10226674A1 Verfahren zur Testung des hormonellen Effekts von Substanzen Method for testing the hormonal effect of substances
01/08/2004CA2492131A1 Live replicating spumavirus vector
01/08/2004CA2492092A1 Immunoglobin single variant antigen-binding domains and dual-specific constructs
01/08/2004CA2492053A1 Peptides with antimicrobial properties and compounds containing same, particularly for preserving food
01/08/2004CA2491861A1 Human igm antibody lysing activated lymphocytes under mediation by homologous complement
01/08/2004CA2491859A1 Human igm antibody inducing apoptosis in hiv-infected cells and remedy for hiv-infection
01/08/2004CA2491567A1 Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
01/08/2004CA2491480A1 Humanized anti-lymphotoxin beta receptor antibodies
01/08/2004CA2491392A1 Compositions and methods for determining the replication capacity of a pathogenic virus
01/08/2004CA2491388A1 Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors
01/08/2004CA2491363A1 Antibodies and uses thereof
01/08/2004CA2491344A1 Marked peptides having affinity for a phospholipid and uses
01/08/2004CA2491343A1 Peptides having affinity for a phospholipid and uses