Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
02/2004
02/05/2004WO2003062264A3 Functional ligand display
02/05/2004WO2003059944A3 Gb virus b based replicons and replicon enhanced cells
02/05/2004WO2003059292A3 Composition and method for maintaining non-enveloped viral vectors
02/05/2004WO2003056904A3 Transgenic plants expressing civps or intein modified proteins and related method
02/05/2004WO2003055911A8 Cystine-knot fold protein
02/05/2004WO2003054139B1 Compositions and methods utilizing dna polymerases
02/05/2004WO2003052052A3 Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
02/05/2004WO2003051832A3 Histamine h2 receptor and uses
02/05/2004WO2003048390A8 A process for the preparation of a non-toxic anthrax vaccine
02/05/2004WO2003046137A3 Hiv envelope v3-ccr5 binding site immunogen
02/05/2004WO2003042397A3 A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
02/05/2004WO2003040304A3 Method of proliferation in neurogenic regions
02/05/2004WO2003026418A3 Methods and compositions for regulation of cell death in plants
02/05/2004WO2003024386A3 Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis
02/05/2004WO2003020947A3 Mid 9002, a human sulfatase family member and uses therefor
02/05/2004WO2003005809A9 Method of elevating glutamic acid content in plant and plants having elevated glutamic acid content
02/05/2004WO2003004682A3 Nucleic acid regulatory sequences and uses thereof
02/05/2004WO2003004525A3 Isolation and purification of plasmodium falciparum merozoite protein-142
02/05/2004WO2002098355A3 Methods and reagents for diagnosis and treatment of insulin resistance and related conditions
02/05/2004WO2002072776A3 Cell culture system for synthesis of infectious hepatitis c virus
02/05/2004WO2002061046A3 Novel nucleic acid and polypeptide molecules
02/05/2004WO2002059373A3 Genes overexpressed in prostate disorders as diagnostic and therapeutic targets
02/05/2004WO2002018632A3 Method for determining the degree of methylation of defined cytosines in genomic dna in the sequence context 5'-cpg-3'
02/05/2004US20040025206 Comprises nucleotide sequences associated with controlling flowering and tissue specific expression of heterologous proteins during flower development
02/05/2004US20040025205 Manipulation of plant senescence using an myb gene promoter and cytokinin biosynthesis gene
02/05/2004US20040025204 Plants and plant products
02/05/2004US20040025203 Plant uridine diphosphate-glucose dehydrogenase genes, proteins, and uses thereof
02/05/2004US20040025202 Nucleic acid molecules associated with oil in plants
02/05/2004US20040025201 True breeding transgenics from plants heterozygous for transgene insertions
02/05/2004US20040025200 Using highly regulated cloning vehicle to control gene expression and transfer within plants; transgenic crop production and public safty
02/05/2004US20040025199 Comprises g-protein couple receptors for identifying modulators of g-protein activity and diagnosis and treatment of infections, nervous system, tumor, autoimmune and inflammatory disorders
02/05/2004US20040025197 Transgenic animal
02/05/2004US20040025196 Comprises nucleotide sequences coding proteins with plenty of SH3 domains (POSH) for preventing viral and bacterial infection and replication; rational drug design; viricides; antiapoptosis agents; bactericides
02/05/2004US20040025193 Method for the rapid selection of homozygous primary cell lines for the production of transgenic animals by somatic cell nuclear transfer
02/05/2004US20040024725 Regulated apoptosis
02/05/2004US20040024537 Hybridization affinity information for the sample polymers such as nucleic acid sequences, is clustered so that the differences, if any, between or among the sample polymers can be readily identified
02/05/2004US20040024536 Determination of optimal local sequence alignment similarity score
02/05/2004US20040024192 19 human secreted proteins
02/05/2004US20040024184 Regulation of human secretin receptor-like gpcr
02/05/2004US20040024181 Comprises polypeptide for treatment, diagnosis, and prevention of cancer, inflammation, nervous system disorders, learning and memory defects and sexual disorders
02/05/2004US20040024064 Determining risk for developing a fat metabolism disorder by comparing a sample Gs alpha expression level with that of the normal level; treating the disorder with a nucleic acid that codes a Gs alpha protein; prognosis; diagnosis;
02/05/2004US20040023963 Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases
02/05/2004US20040023918 Antisense modulation of inhibitor-kappa B kinase-gamma expression
02/05/2004US20040023917 Treatment of asthma with oligonucleotides which specifically hybridize with nucleic acids encoding B7 proteins.
02/05/2004US20040023911 Delivering a naked or isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of a naked polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells
02/05/2004US20040023908 Antisense modulation of a20 expression
02/05/2004US20040023907 Infection model
02/05/2004US20040023905 Antisense modulation of LAR expression
02/05/2004US20040023904 Antisense modulation of PTPRA expression
02/05/2004US20040023903 Single-stranded end-capped oligonucleotide mediated targeted gene repair and modification and uses thereof
02/05/2004US20040023902 Delivery system contains a fusion protein having a target moiety and a nucleic acid binding moiety, and a nucleic acid sequence bound to the nucleic acid binding moiety of the fusion protein. The target moiety can be an antibody or a
02/05/2004US20040023883 IGF-I and insulin variants are provided that selectively bind to IGFBP-1 or IGFBP-3. These agonist variants are useful, for example, to improve the half-lives of IGF-I and insulin, respectively.
02/05/2004US20040023877 Plasminogen fragments containing kringle region domains having anti-angiogenic activity and terned angiostatin protein. The plasminogen fragments of the present invention may be used for the treatment of angiogenesis-dependent diseases such as
02/05/2004US20040023876 Reagents which regulate human serotonin receptor precursor and reagents which bind to human serotonin receptor precursor gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited
02/05/2004US20040023875 Insect inhibitory bacillus thuringiensis proteins, fusions, and methods of use therefor
02/05/2004US20040023863 Multi-tier approach to the administration of growth factor proteins in the treatment of heart disease. Also disclosed is a method to evaluate the effectiveness of the administration of growth factor proteins comprising the clinical assay of
02/05/2004US20040023862 Newly identified uses of BRS3 polypeptides and polynucleotides encoding such polypeptides, to their use in therapy of ischemia, of neurodegenerative diseases, of memory and attention disorders, and in identifying compounds which may be
02/05/2004US20040023861 Isolated cysteinyl leukotriene receptor polypeptide comprising amino acid sequence of SEQ ID NO: 2 or variant thereof which is capable of binding a leukotriene; or fragment of (i) or (ii) which is capable of binding a leukotriene.
02/05/2004US20040023860 Methods and compositions for inhibiting neoplastic cell growth
02/05/2004US20040023856 Purified DNA comprising a sequence encoding a B1k chain of laminin. Vector comprising a DNA sequence encoding a B1k protein.
02/05/2004US20040023854 Adiponectin and uses thereof
02/05/2004US20040023395 Transgenic tetraploid plants and methods of production
02/05/2004US20040023392 Use in introducing predetermined change at predetermined location in target gene in living cell; oligodeoxynucleotide is modified by attachment of 3' and 5' blocking substituents such as a 3'-3'linked cytosine nucleotide and a 5' linked dye
02/05/2004US20040023391 Using surface-mediated protein transfected cell microarrays to screen polypeptide and enzyme activities; high throughput assay; drug screening
02/05/2004US20040023390 Using small interfering RNA sequences for treating neurodegenerative diseases; gene expression inhibition
02/05/2004US20040023389 Plasmid coding proteins associated with immune response for immunotherapeutic treatment of cancer; gene therapy; anticarcinogenic agents
02/05/2004US20040023388 Modulation of meiotic recombination
02/05/2004US20040023385 Comprises oligonucleotides for gene expression inhibition of requiem apoptosis zinc finger gene (REQUIEM) and treatment of cancer, aberrant apoptosis and developmental disorders
02/05/2004US20040023384 Antisense modulation of G protein-coupled receptor 12 expression
02/05/2004US20040023379 Comprises oligonucleotides for gene expression inhibition of hepatoma derived growth factor (HDGF) for treating cancer and metabolic disorder
02/05/2004US20040023378 Antisense modulation of KIAA1531 protein expression
02/05/2004US20040023372 Tubular nanostructures
02/05/2004US20040023368 Apparatus for light controlled parallel synthesis of molecular sequence arrays on solid surfaces
02/05/2004US20040023366 Surface for the immobilization of ligands
02/05/2004US20040023355 Subtilase variants
02/05/2004US20040023353 Comprises heat resistant carbonyl hydrolase for use in laundry detergents and textile treatment
02/05/2004US20040023351 Killing bacterial contaminats in mammalian milk via controlled heating of liquids
02/05/2004US20040023347 Genetic engineering of bacterial enzymes; 3-hydroxypropionate and 3-hydroxyvalerate units are derived from the enzyme catalysed conversion of diols
02/05/2004US20040023343 Biosynthetic genes for spinosyn insecticide production
02/05/2004US20040023342 Synthesizing polyketide fusion protein comprising acyltransferase domain for use as anthelminthic, insecticide, antitumor, immunosuppressant, fungicidal and/or bactericidal agents
02/05/2004US20040023339 Transgenic cell culture for preparing monoclonal antibodies for treatment and prevention of cancer
02/05/2004US20040023338 Comprises genetically engineered interleukin 4 polypeptide for diagnosing and treating inflammatory, autoimmune, nervous system, cardiovascular, cancer and infectious diseases
02/05/2004US20040023337 IL-13 mutein proteins, antibodies, compositions, methods and uses
02/05/2004US20040023335 IL-17 like molecules and uses thereof
02/05/2004US20040023334 Comprises lactoferrin fusion protein for diagnosis, prevention treatment and prognosis of nervous system, respiratory, cardiovascular and/or reproductive system disorders
02/05/2004US20040023333 Production of recombinant blood clotting factors in human cell lines
02/05/2004US20040023332 Genes of il-12p40 subunit mutated for improving the activity of il-12 and thereof for dna vaccine adjuvant
02/05/2004US20040023331 Comprises membrane protein for diagnosis, prevention and treatment cell proliferative disorders; tumor detection
02/05/2004US20040023330 Preparing biosensor for measuring and analyzing glucose concentration of fluids diabetes
02/05/2004US20040023329 Preparing cells for use as bioreactors for expression of heterologous polypeptides
02/05/2004US20040023327 Using site directed mutagenesis to cause nucleotide sequences alterations in target protein; polypeptide engineering
02/05/2004US20040023326 Comprises inhibitory monoclonal antibody for controlling metabolic processes associated with cytochrome c oxidase/debrisoquine hydroxylase; drug screening and development; competetive binding
02/05/2004US20040023325 Comprises genetically engineered outer surface protein for use in treatment and prevention of lyme disease; genetic vaccines
02/05/2004US20040023315 Transgenic yeast cells coding membrane receptor proteins for diagnosis and treatment of pancreatitis, pancreatic cancer, gastrointestinal disorders and irritable bowel disease
02/05/2004US20040023313 Comprises monoclonal antibody which specifically binds osteoprotegerin ligand (OPGL) for diagnosis, prevention and treatment of bone disorders
02/05/2004US20040023307 DNA encoding a novel RG1 polypeptide
02/05/2004US20040023291 Comprises insect polypeptide for use in hemolysis and immunosuppression; immunotherapy
02/05/2004US20040023283 Comprises nucleotide sequences coding polypeptide for diagnosis, prevention and treatment of immunological, hematopoietic and inflammatory disorders
02/05/2004US20040023282 Obtaining chromosomal DNA from plants for preparing expression vectors comprising artificial chromosomes
02/05/2004US20040023281 Production of lysosomal enzymes in plants by transient expression