Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/2004
06/17/2004US20040115202 monospecific antibody which specifically binds an epitope of a mammalian DPPIV (dipeptidyl peptidase IV, also known as CD26).
06/17/2004US20040115199 Method for down-regulating osteoprotegerin ligand activity
06/17/2004US20040115188 Enzyme with proteolytic activity
06/17/2004US20040115184 Methods and compositions for modifying apolipoprotein b mrna editing
06/17/2004US20040115180 Carrier chimeric proteins targeted carrier chimeric proteins and preparation thereof
06/17/2004US20040115179 treating and preventing gastrointestinal diseases as well as lowering serum cholesterol
06/17/2004US20040115166 Method of treatment and prophylaxis
06/17/2004US20040115130 Methods using O6 -alkyguanine-dna alkyltransferases
06/17/2004DE10255852A1 Verfahren zur Expressionsveränderung von Polypeptiden in rekombinanten Expressionssystemen A process for the change in expression of polypeptides in recombinant expression systems
06/17/2004DE10248166A1 Anti-Kazlauskas-Lipasen Anti-Kazlauskas lipases
06/17/2004DE10234577A1 Method for recombination of double-stranded DNA from different diversification strategies, useful e.g. for assembling synthetic genes, based on amplification with primers that create strand breaks
06/17/2004CA2706873A1 Modified neomycin-phosphotransferase gene that increases expression rates of co-integrated gene and uses thereof
06/17/2004CA2508514A1 Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
06/17/2004CA2508223A1 Germ-responsive promoter
06/17/2004CA2508052A1 Control of apoptosis using a complex of an oligonucleotide and a regulatory peptide
06/17/2004CA2507863A1 Methods and materials for modulating trpm2
06/17/2004CA2507714A1 Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products
06/17/2004CA2507494A1 Rationally designed antibodies
06/17/2004CA2507189A1 Fragmentation-based methods and systems for sequence variation detection and discovery
06/17/2004CA2507036A1 Materials and methods for treating ocular-related disorders
06/17/2004CA2507007A1 Bioremediation with transgenic plants
06/17/2004CA2506999A1 L-rhamnose-inducible expression systems
06/17/2004CA2506748A1 Method for in vitro selection of 2'-substituted nucleic acids
06/17/2004CA2506744A1 Plant production of immunoglobulins with reduced fucosylation
06/17/2004CA2506734A1 Fish disease models and uses thereof
06/17/2004CA2506629A1 Modified antibodies stably produced in milk and methods of producing same
06/17/2004CA2485341A1 Use of spliceosome mediated rna trans-splicing to confer cell selective replication to adenoviruses
06/17/2004CA2469724A1 Mutant glycoproteins
06/16/2004EP1429274A2 Methods for sequence display and homology search
06/16/2004EP1428892A1 Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
06/16/2004EP1428891A1 Novel gene nedl-1
06/16/2004EP1428887A1 Replication-competent herpes simplex virus mediates destruction of neoplastic cells
06/16/2004EP1428886A1 Improved retroviral vectors for gene therapy
06/16/2004EP1428885A1 Method of modifying genome in higher plant
06/16/2004EP1428884A1 Sulfohydrolase I from Chondrus crispus seaweed, and uses thereof
06/16/2004EP1428883A1 Megakaryocyte stimulating factors
06/16/2004EP1428882A1 Nucleic acids showing difference in expression between hepatoblastoma anc normal liver
06/16/2004EP1428881A1 Hematopoietic stem cell proliferation regulators and polynucleotides encoding the same
06/16/2004EP1428880A1 Kidney-specific urate transporter and gene thereof
06/16/2004EP1428879A1 Polynucleotide vaccine
06/16/2004EP1428876A1 Novel amide hydrolase gene
06/16/2004EP1428834A1 Ligands for flt3 receptors
06/16/2004EP1428810A2 Libraries of oligomers labelled with different tags
06/16/2004EP1428023A2 Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
06/16/2004EP1427860A2 Storing and detecting nucleic acid administered to a solid carrier
06/16/2004EP1427857A2 Mid 4460, a human tyrosine phosphatase family member and uses therefor
06/16/2004EP1427856A2 Fusion proteins useful for detecting analytes
06/16/2004EP1427855A2 Method and reagents for identifying gene targets for treating breast cancer
06/16/2004EP1427852A2 Single nucleotide amplification and detection by polymerase
06/16/2004EP1427851A2 Method of determining the nucleotide sequence of oligonucleotides and dna molecules
06/16/2004EP1427849A2 Method of screening for drug hypersensitivity reaction
06/16/2004EP1427848A2 Dry solid medium for storage and analysis of genetic material
06/16/2004EP1427847A2 Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
06/16/2004EP1427846A2 Method of identifying glycosyl transferase binding compounds
06/16/2004EP1427842A2 Mid 9002, a human sulfatase family member and uses therefor
06/16/2004EP1427841A2 Nucleic acid-associated proteins
06/16/2004EP1427838A1 Plant enzymes for bioconversion
06/16/2004EP1427837A2 Modular transfection systems
06/16/2004EP1427836A2 Pseudotyped retroviral vector system
06/16/2004EP1427835A1 Method for purification of viral vectors having proteins which bind sialic acid
06/16/2004EP1427834A1 A method to modify cell number, architecture and yield of plants by overexpressing the e2f transcription factor
06/16/2004EP1427833A1 Novel nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
06/16/2004EP1427832A2 Methyltransferase genes and uses thereof
06/16/2004EP1427831A1 Yeast membrane protein expression system and its application in drug screening
06/16/2004EP1427830A2 Bv8 NUCLEIC ACIDS AND POLYPEPTIDES WITH MITOGENIC ACTIVITY
06/16/2004EP1427829A2 Multivalent protein conjugate with multiple ligand-binding domains of receptors
06/16/2004EP1427828A2 Random integration of a polynucleotide after in vivo linearization
06/16/2004EP1427827A2 Synthetic hcv envelope proteins and their use for vaccination
06/16/2004EP1427826A2 Hiv-gag codon-optimised dna vaccines
06/16/2004EP1427825A2 Cdna encoding the human alpha2 delta4 calcium channel subunit
06/16/2004EP1427824A2 Use of microbiology non-viral substances for treating acne
06/16/2004EP1427823A2 High throughput directed evolution by rational mutagenesis
06/16/2004EP1427822A2 Nucleic acid for cloning vector
06/16/2004EP1427820A2 Modified factor ix
06/16/2004EP1427819A2 Lactobacillus n-deoxyribosyl transferases, corresponding nucleotide sequences and their uses
06/16/2004EP1427818A2 Nucleic acid molecules coding for a dextran-saccharase catalysing the synthesis of dextran with alpha 1,2-osidic sidechains
06/16/2004EP1427816A1 Site-specific recombinase based method for producing adenoviral vectors
06/16/2004EP1427815A2 Methods for producing an active constituent of a pharmaceutical or a diagnostic agent in an mdck cell suspension culture
06/16/2004EP1427812A2 Production of cultured human mast cells and basophils for high throughput small molecule drug discovery
06/16/2004EP1427809A1 Method for transforming i amycolatopsis sp. /i dsm 9991 and dsm 9992
06/16/2004EP1427807A2 Estrogen receptor alpha variants and methods of detection thereof
06/16/2004EP1427806A2 Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof
06/16/2004EP1427758A2 Compositions and methods of treating diabetes
06/16/2004EP1427757A1 Late gestation lung genes, fragments and uses thereof
06/16/2004EP1427756A1 Modified human growth hormone
06/16/2004EP1427754A1 Nucleic acid and polypeptide linked to breast cancer and uses therefor
06/16/2004EP1427753A2 Peptides and proteins binding to glu-pro motifs, therapeutical compositions containing them and their applications
06/16/2004EP1427752A2 New hepatitis c virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
06/16/2004EP1427751A2 Trk polypeptide purification method
06/16/2004EP1427750A1 Modified transferrin fusion proteins
06/16/2004EP1427747A2 Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
06/16/2004EP1427746A2 Protein and nucleic acid expression systems
06/16/2004EP1427744A2 A system for antibody expression and assembly
06/16/2004EP1427742A1 Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof
06/16/2004EP1427450A2 Inhibition of rna function by delivery of inhibitors to animal cells
06/16/2004EP1427449A1 Anti-cancer agents comprising disintegrin genes and the treating methods
06/16/2004EP1427444A2 West nile vaccine
06/16/2004EP1427443A1 Vaccine using papilloma virus e proteins delivered by viral vector
06/16/2004EP1427441A2 Composite superimmunogen for bi-functional vaccine use for the treatment of illnesses associated with a stromal tissue disorder
06/16/2004EP1427431A2 Bioadhesive compositions and methods for enhanced mucosal drug absorption