Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/2005
08/11/2005US20050176149 Process for the reversible functional inactivation of the mismatch repair system
08/11/2005US20050176148 Selection marker gene
08/11/2005US20050176147 Method for obtaining a cell model capable of reproducing in vitro the metabolic idiosyncrasy of humans
08/11/2005US20050176146 Using vector transformation to generate heat resistant viral particles
08/11/2005US20050176145 Using transposase activated plasmid as tool in generating transgenic animal cells; gene therapy and heterologous gene transfer
08/11/2005US20050176142 Mammalian megakaryocyte progenitor cell
08/11/2005US20050176130 Functional mutations in respiratory syncytial virus
08/11/2005US20050176129 Adenovirus vector
08/11/2005US20050176128 Method for assembling subunits into capsoids
08/11/2005US20050176127 Primers; plasmid libraries; citrate synthases; glutamate dehydrogenases; phosphofructokinases
08/11/2005US20050176126 Lachrymatory-factor synthase for use in identifying medicants for dry eye; producing onions with reduced lachrymatory factor and eye stinging
08/11/2005US20050176118 Esterases with lipase activity
08/11/2005US20050176117 Using sterospecific carboxylesterase variant for bioremediation of pyrethroids
08/11/2005US20050176113 Microorganism producing L-threonine having inactivated tyrR gene, method of producing the same and method of producing L-threonine using the microorganism
08/11/2005US20050176106 Use of the RTX secretion system to achieve heterologous polypeptide secretion by Vibrio cholerae
08/11/2005US20050176104 Using overexpression of nucleotide sequences coding tumor associated antigen as diagnostic/prognostic tool in detection of cancer
08/11/2005US20050176103 Produced by recombinant techniques and polynucleotides encoding the polypeptides; used to stimulate angiogenesis for wound healing and for vascular tissue repair
08/11/2005US20050176100 Zinc metalloprotease angiotensin-converting enzyme (ZACE-1) for use in identifying blood pressure and fertility modulators
08/11/2005US20050176099 Plasmid system for multigene expression
08/11/2005US20050176097 Bacterial bioreactor for propagation of enzymatic polypeptides
08/11/2005US20050176096 Stabilized biocatalysts and methods of bioconversion using the same
08/11/2005US20050176095 Sulfur-assimilating regulatory protein for use as tool in controlling transgenic cells expressing heterologous gene sequences
08/11/2005US20050176094 Polypeptide having immunomodulatory activity, antiviral activity, and antitumor activity; polynucleotides, expression vectors , probes and antibodies; predicting responsiveness to treatment with interferon- alpha and other interferons which act at the Type 1 interferon receptor
08/11/2005US20050176091 Process for producing kiss-1 peptide
08/11/2005US20050176083 Blood protein fusion comprising serine-protease (SP) domain for use in treatment of thrombosis a nd blood coagulation disorders
08/11/2005US20050176070 Immunoglobulin array for use in monitoring polypeptide binding
08/11/2005US20050176069 Drug screening; neuropeptides; ligands; mimetics; anthelmin-tics; use for screening and identification of materials that inhibit/interfer with the neurological activity of targeted invertebrates while minimizing effects on non-pest species
08/11/2005US20050176062 Method of identifying ligands for nuclear receptors
08/11/2005US20050176060 Crystal structure
08/11/2005US20050176052 Method of handling an oocyte during in vitro fertilization
08/11/2005US20050176045 SNP discriminatory siRNA
08/11/2005US20050176044 Polynucleotides and polypeptides encoding receptors
08/11/2005US20050176042 Novel proteins expressed in human cell lines, human fetal brain, spinal cord, lymph node, prostate, testis, thyroid, pancreas; share structural similarity with animal hydroxylases, eg. tryptophan hydroxylases; biosynthesis of neurologically active compounds
08/11/2005US20050176041 Using membrane proteins as tool in diagnosis, prevention and treatment of cell proliferative disorders
08/11/2005US20050176040 Novel human protease and polynucleotides encoding the same
08/11/2005US20050176038 Transcribed non-naturally occurring RNA sequences which form hairpin structures for use in treatment of cell proliferative disorders; gene therapy; antisense agents
08/11/2005US20050176036 Generating solid support compring immobilized plasmids comprising fragment geneomic DNA; gene expression analysis
08/11/2005US20050176027 Nucleic acid extraction method
08/11/2005US20050176025 RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
08/11/2005US20050176024 chemically synthesized double stranded siNA that directs cleavage of EGFR such as HER1, HER2, HER3 or HER4; diagnosis or treatment of cancer for example
08/11/2005US20050176022 Vertebrate telomerase genes and proteins and uses thereof
08/11/2005US20050176021 Vectors for propagating and expressing RGL3 nucleic acids, host cells comprising the nucleic acids; proteins; cancer
08/11/2005US20050176020 I-CAM related protein
08/11/2005US20050176018 Increased nuclease resistance; gene expression inhibition
08/11/2005US20050176017 Bioreactive allosteric polynucleotides
08/11/2005US20050176016 Missense mutations and in-frame deletions
08/11/2005US20050176014 Fluorescent hybridization probes with reduced background
08/11/2005US20050176013 Identifying modulators of 3'-phosphoadenosine 5'-phosphosulfate synthase 1(PAPPS-1) activity; antitumor agents; tumor diagnostics
08/11/2005US20050176005 Functional ligand display
08/11/2005US20050176004 Rheumatoid arthritis disease sensitive gene, its protein, method and kit of judging the onset of rheumatoid arthritis using the same, and method and drugs for treating rheumatoid arthritis
08/11/2005US20050176002 Methods for detecting ovarian cancer
08/11/2005US20050175993 Using reverse transcription to generate complimentary DNA data pools; gene expression analysis
08/11/2005US20050175990 Method for typing and detecting HBV
08/11/2005US20050175987 Fluorescent multiplex hpv pcr assays using multiple fluorophores
08/11/2005US20050175985 Cold-adapted equine influenza viruses
08/11/2005US20050175736 preparing protein hydrolysates useful as flavor improving agents by subjecting a protein substrate to an endopeptidase and a polypeptide having carboxypeptidase activity
08/11/2005US20050175710 For transfection into cells in vitro or in vivo
08/11/2005US20050175633 Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV), proteins encoded by the polynucleic acids, vaccines based on the proteins and/or polynucleic acids, a method of protecting a pig from a PRRSV and a method of detecting a PRRSV
08/11/2005US20050175624 Utilizing vascular epithelial growth factor (VEGFR1) polypeptides, fragments and/or encoding oligonucleotides
08/11/2005US20050175618 Delivery of agents directly to tumor cell cytoplasm
08/11/2005US20050175612 Growth differentiation factor-8
08/11/2005US20050175606 Cyclic single-chain trispecific antibody
08/11/2005US20050175594 Myoviridae; also used to treat animals infected with Listeria monocytogenes
08/11/2005US20050175592 Storage stability; use of bulking agents, cryoprotectants and lyoprotectants imparts desired properties that allow both lyophilized and liquid adenovirus formulations to be stored at 4 degrees C. for up to 6 months and retain an infectivity between 60-100% of the starting infectivity
08/11/2005US20050175591 For efficient mRNA termination/translation; using this shorter dual termination/polyadenylation signal and avoiding the need for large and cumbersome polyadenylation signals, expression vectors may be engineered to carry considerably larger genes
08/11/2005US20050175590 Viral expression vectors
08/11/2005US20050175589 Anti-neoplastic viral agents
08/11/2005US20050175588 Contain one or more recombinant molecule(s) expressed on a cellular surface and incorporated and/or associated with a particle that does not require cellular entry for delivery; for stimulation of biological processes, inactivation of inhibitory factors, scavenging and/or detoxifying
08/11/2005US20050175587 Inhibits cancer cell growth especially epithelial cancer cell growth; host cell and a drug containing the vector; for the treatment of cancers, by gene therapy
08/11/2005US20050175584 Functionalized colloidal metal compositions and methods
08/11/2005US20050175582 Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
08/11/2005US20050172424 Lmt turmor suppressor gene
08/11/2005DE19648656B4 Vorrichtung zum Beschleunigen von Partikeln auf Zellen zum ballistischen Transfer Apparatus for accelerating particles to cells in ballistic transfer
08/11/2005CA2595619A1 Enhanced secretion/retention of growth hormone releasing hormone (ghrh) from muscle cells by species-specific signal peptide
08/11/2005CA2555367A1 Apoe genetic markers associated with age of onset of alzheimer's disease
08/11/2005CA2554846A1 Method of quickly measuring factor causing early flocculation of yeast
08/11/2005CA2554755A1 Functionalized colloidal metal compositions and methods
08/11/2005CA2554753A1 Composition and method for elevating gene transfer efficiency
08/11/2005CA2554623A1 Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of colon cancer
08/11/2005CA2554599A1 Novel brain natriuretic peptide variants and methods of use thereof
08/11/2005CA2554440A1 Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer
08/11/2005CA2554424A1 Controlled and sustained delivery of nucleic acid-based therapeutic agents
08/11/2005CA2554410A1 Biotherapeutics, diagnostics and research reagents
08/11/2005CA2554403A1 Gastrointestinal proliferative factor and uses thereof
08/11/2005CA2554216A1 Methods and compositons for treating cancer
08/11/2005CA2553989A1 Production of host cells containing mutiple integrating vectors by serial transduction
08/11/2005CA2553814A1 Treating a viral disorder
08/11/2005CA2553759A1 Glyphosate tolerant plants and methods of making and using the same
08/11/2005CA2553676A1 Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
08/11/2005CA2553435A1 Method for overproducing a specific recombinant protein with p. cinnabarinus monokaryotic strains
08/11/2005CA2553187A1 Heterodimeric follicle stimulating hormone-fc (fsh-fc) fusion proteins for the treatment of infertility
08/11/2005CA2553104A1 Antisense oligomers and methods for inducing immune tolerance and immunosuppression
08/11/2005CA2552391A1 Oligonucleotide and the use thereof for modulating an isoform c beta-1 protein-kinase in the form of a skin depigmentation agent
08/11/2005CA2549263A1 Systems for tightly regulated gene expression
08/11/2005CA2548992A1 Immunotherapy compositions, method of making and method of use thereof
08/11/2005CA2547695A1 Advanced microorganism for producing 1,2-propanediol
08/11/2005CA2496595A1 Development of controlled total vegetative growth for prevention of transgene escape from genetically modified plants
08/10/2005EP1562045A2 Bioarray chip reaction apparatus and its manufacture
08/10/2005EP1561822A1 Detection of DNA damaging agents
08/10/2005EP1561819A1 Method of transferring gene into t cells