| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 06/29/2010 | US7745581 T-bet compositions and methods of use thereof |
| 06/29/2010 | US7745572 Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| 06/29/2010 | US7745485 Inhibiting metastasis of cancer cells by administering a phosphatidyl inositol 3-kinase inhibitor such as Wortmannin or LY294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one) |
| 06/29/2010 | US7745465 Antiischemic agents; antiinflammatory agents; antiallergens; autoimmune disease |
| 06/29/2010 | US7745420 stability, high effectiveness and low toxicity; for treating pulmonary/respiratory diseases such as cystic fibrosis, asthma, chronic bronchitis, chronic obstructive lung disease, eosinophilic bronchitis |
| 06/29/2010 | US7745418 Compositions and methods for inhibiting viral replication |
| 06/29/2010 | US7745416 Method for in vivo regulation of cardiac muscle contractility |
| 06/29/2010 | US7745406 Kit which determines concentration of phosphate metabolizing protein and utilizes profile as indicator of hypo/hyperphosphatemic disorders |
| 06/29/2010 | US7745405 Cancer treatment by administration of a synthetic peptide comprising a sequence of amino acids within the p53 protein and a membrane penetrating leader sequence; fusion proteins for tissue-targeted therapy |
| 06/29/2010 | US7745395 Recombinant protease comprising prostate-specific protease cleavage site and deficient in furin cleavage site for use as therapeutic agent in treatment of cell proliferative disorders; antitumor agents |
| 06/29/2010 | US7745218 developing novel strains containing deletions of specific chromosome sites, using transposon and cre recombinase/locus of crossover in P1(loxP) site-specific recombination by Cre gene expression from a Cre genetic vector; genetic engineering |
| 06/29/2010 | US7745214 for assessing the effect of candidate chemotherapeutic drugs on the growth of brain tumors; fibroblast growth factor expressing cells and diagnosis and treatment of tumors; antiproliferative agents |
| 06/29/2010 | US7745213 nucleotide sequences coding potassium chanel protein for use in identifying modulator for prevention and treatment of cardiovascular/myocardial disorders; utilized to diagnose and screen for short QT syndrome, long QT syndrome, Brugada syndrome and progressive conduction disease |
| 06/29/2010 | US7745212 Melanoma antigens and their use in diagnostic and therapeutic methods |
| 06/29/2010 | US7745200 selecting a formaldehyde resistant cell; therefore useful as a selectable marker in methylotrophic yeasts; genetic engineering |
| 06/29/2010 | US7745195 Method for the preparation of an evolved microorganism for the creation or the modification of metabolic pathways |
| 06/29/2010 | US7745193 recombinant nucleotide sequence which codes upon expression for at least a part of a bifunctional hybrid active-site serine beta -lactamase protein |
| 06/29/2010 | US7745190 Endoribonuclease |
| 06/29/2010 | US7745189 encodes a cotA polypeptide having serine/threonine kinase activity ; modulation of genes associated with hyphal growth in filamentous fungi |
| 06/29/2010 | US7745188 Heat resistant and error-prone polymerase for use as mutational tool in genetic analysis |
| 06/29/2010 | US7745186 Ribulose, 1,5-bisphosphate carboxylase/oxygenase polypeptides and related polynucleotides |
| 06/29/2010 | US7745184 Using transgenic escherichia expressing galactose-proton symporter and reduced glycerolaldehyde 3-phosphate dehydrogenase as bioreactor for 1,3-propanediol production |
| 06/29/2010 | US7745180 removing erythrocytes and blood components other than leukocytes from the whole blood by filtration, then lysing leukocytes of the whole blood, and quantifying the specific mRNA in the lysate; leukocyte filters attached to oligo(dT)-immobilized multi-well plates; use in diagnosis, blood bank screening |
| 06/29/2010 | US7745179 Lentiviral producer cell; such as mounse transthyretin (mTTR) promoter (antibody); recombinant lentiviruses and transfer vectors for transgene delivery and gene therapy; blood coagulation factor IX; antihemopohilic factor |
| 06/29/2010 | US7745177 using a xylitol dehydrogenase-deficient mutant of xylitol producing microorganism; achieved through modification of the metabolic pathway of the xylitol producing microorganism, preferably a natural xylose-assimilating yeasts and fungi, by disrupting or inactivating the expression of desired genes |
| 06/29/2010 | US7745176 using an E. coli expression system for the large scale production of IL-21 to a level of greater than 1 g/L in fed batch fermentation |
| 06/29/2010 | US7745174 co-expressing two heterotypes of Hepatocyte Growth Factor (HGF) comprising transforming or transfecting to a cell a DNA construct; for prevention and treatment of ischemic and liver disorders |
| 06/29/2010 | US7745172 Via L-aspartic acid- alpha,beta-diester and L-phenylalanine using enzyme that has ability to selectively link L-phenylalanine to alpha -ester site of L-aspartic acid- alpha,beta-diester through peptide bond/nucleophilic attack; easy, high yield and inexpensively without going through a complex synthesis |
| 06/29/2010 | US7745170 Process for producing carotenoid compound |
| 06/29/2010 | US7745165 Calibration of colorectal cancer; gene expression profile; administering to human an antibody which binds to protein markers |
| 06/29/2010 | US7745164 Methods of modulating apoptosis using inhibitors of brain-localized protein kinases homologous to homeodomain-interacting protein kinases |
| 06/29/2010 | US7745160 Method of amplifying ATP and use thereof |
| 06/29/2010 | US7745152 Method for determining genotoxicity |
| 06/29/2010 | US7745140 Cell proliferation; tissue engineering; screening, detection of antigens; immunitherapy; development of vaccine; antitumor, anticancer agents |
| 06/29/2010 | US7745137 analyzing two polymorphisms in stromelysin 1 gene and plasminogen activator inhibitor-1 gene in a nucleic acid sample; high accuracy and predictability |
| 06/29/2010 | US7745130 Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof |
| 06/29/2010 | US7745126 field of combination oligomers, including the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, libraries and other compositions. |
| 06/29/2010 | US7745124 Performing a hybridization reaction in the reaction temperature region of a reaction solution using oligonucleotides |
| 06/29/2010 | US7745114 Compositions and methods for identifying and targeting cancer cells of alimentary canal origin |
| 06/29/2010 | US7745111 Molecular markers of plant embryogenesis |
| 06/29/2010 | US7745109 Regulation of cell growth by MUC1 |
| 06/29/2010 | US7745108 Method for identifying terpene synthase |
| 06/29/2010 | US7744912 Forming a biopolymer by polymerization or crosslinking through self-selective reaction between a strong multifunctional nucleophile such as amine or thiol and a conjugated unsaturated bond; preparation of highly biomimetic synthetic polymers |
| 06/29/2010 | US7744907 Ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in the method |
| 06/29/2010 | US7744906 Chaperone proteins comprising at least one of three specific nucleotide sequences; analgesics; side effect reduction; lastslonger than narcotics; relieving any type of pain |
| 06/29/2010 | US7744903 Epitopes confirmed to be recognized by T-cells derived from herpetic lesions or uterine cervix; vaccination; host cells |
| 06/29/2010 | US7744902 Respiratory syncytial virus vaccines expressing protective antigens from promotor-proximal genes |
| 06/29/2010 | US7744900 Expression cassettes provided comprising a promoter operably linked to a nucleic acid which when transcribed in vivo, forms double stranded RNA that induces the production of interferon(alpha, beta, or gamma) either directly or indirectly, which in turnmay upregulate MHC Class I and/ or II |
| 06/29/2010 | US7744899 Preferentially kills tumor cells and not healthy cells; expresses only one gamma 134.5 gene copy and that comprises an expressibletumor-growth-inhibiting cytokine-encoding DNA; anticarcinogenic agents; antitumor agents; nervous system disorders; immunotherapy;tissue-targeted therapy |
| 06/29/2010 | US7744896 therapeutic vaccine anti-HIV, anti-AIDS and against tumors and syndromes associated with HIV infection |
| 06/29/2010 | US7744892 Optimized expression of HPV 52 L1 in yeast |
| 06/29/2010 | US7744886 Methods for interfering with rank signaling |
| 06/29/2010 | US7744881 for cancer treatment by inducing apoptosis; monoclonal antibodies; drug conjugated with polyoxyethylene glycol or enzyme or radioisotope, fluorescent compound or chemiluminescent compound; genetic engineering; biodrugs; anticarcinogenic agents |
| 06/29/2010 | US7744880 cell proliferation-inhibiting activity by ADCC (antibody-dependent cell-mediated cytotoxicity) activity and CDC (complement-dependent cytotoxicity); hepatic cancer |
| 06/29/2010 | US7744873 Extracting DNA from a blood or buccal cell sample, PCR, resolution, and identification of differences in sequences between the extracted DNA and PCR primers; drug screening |
| 06/29/2010 | US7744862 Propagating and isolating cell growth factors from prokaryotic systems using ion exchange and reverse phase chromatography; bioreactor and heterologous gene expression |
| 06/29/2010 | CA2636421C A method of platelet and whole blood storage |
| 06/29/2010 | CA2482747C Vaccine composition for preventing meningococcal disease |
| 06/29/2010 | CA2452818C Tyrosyl-trna synthetase variants |
| 06/29/2010 | CA2452471C Enhancement of transfection of dna into the liver |
| 06/29/2010 | CA2428158C Methods for isolating novel antimicrobial agents from hypermutable mammalian cells |
| 06/29/2010 | CA2417923C Vaccination against host cell-associated herpesviruses |
| 06/29/2010 | CA2398467C Antibody for detecting chlamydia pneumoniae |
| 06/29/2010 | CA2390082C Novel hcv non-structural polypeptide |
| 06/29/2010 | CA2370477C Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein |
| 06/29/2010 | CA2360053C Plant gene |
| 06/29/2010 | CA2358439C Metastasis models using green fluorescent protein (gfp) as a marker |
| 06/29/2010 | CA2337969C Compound and method for the prevention and/or the treatment of allergy |
| 06/29/2010 | CA2326374C Process for the recovery and purification of a recombinant protein from a cell |
| 06/29/2010 | CA2326373C Methods and substances for preventing and treating autoimmune disease |
| 06/29/2010 | CA2325345C Medicaments for inducing cytotoxic t-cells |
| 06/29/2010 | CA2319665C Processes for isolating, amplifying and characterizing dna |
| 06/29/2010 | CA2312188C Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation |
| 06/29/2010 | CA2291878C Lactic acid bacterial starter cultures and compositions thereof |
| 06/29/2010 | CA2289600C Techniques and compositions for treating heart failure and ventricular remodeling by in vivo delivery of angiogenic transgenes |
| 06/29/2010 | CA2274498C Novel expression vectors containing accessory molecule ligand genes and their use for immunomodulation and treatment of malignancies and autoimmune disease |
| 06/29/2010 | CA2252372C Pathogenic escherichia coli associated protein |
| 06/29/2010 | CA2251560C Pesticidal toxins |
| 06/29/2010 | CA2236700C Immunity against pasteurella haemolytica leukotoxin |
| 06/29/2010 | CA2218909C Isolating and culturing schwann cells |
| 06/29/2010 | CA2195169C Transfection competent molecules |
| 06/29/2010 | CA2187740C Dna encoding bradykinin b1 receptor |
| 06/29/2010 | CA2168409C G cap-stabilized oligonucleotides |
| 06/29/2010 | CA2163976C Methods and compositions for inhibiting cd14 mediated cell activation |
| 06/29/2010 | CA2134030C Soluble interferon .alpha.-receptor, its preparation and use |
| 06/24/2010 | WO2010071897A2 Engineering heat-stable disease resistance in plants |
| 06/24/2010 | WO2010071852A2 Oligonucleotide micelles |
| 06/24/2010 | WO2010071851A2 Conversion of co2 to higher alcohols using photosysnthetic microorganisms |
| 06/24/2010 | WO2010071769A2 Chimeric l. monocytogens in1b protein |
| 06/24/2010 | WO2010071608A1 Genetic transformation of jatropha curcas |
| 06/24/2010 | WO2010071602A1 Pcr-based method of synthesizing a nucleic acid molecule |
| 06/24/2010 | WO2010071454A1 Adeno-associated viral vectors and uses thereof |
| 06/24/2010 | WO2010071431A1 Method of breeding cysdv-resistant cucumber plants |
| 06/24/2010 | WO2010071418A1 Recql5 in homologous recombination |
| 06/24/2010 | WO2010071249A2 The diagnosing method of cancer using dosage sensitive gene group and methylation degree of methyl transition zone thereof |
| 06/24/2010 | WO2010071210A1 Chondrocyte-like cell, and method for producing same |
| 06/24/2010 | WO2010071206A1 DNA CONSTRUCT FOR TRANSCRIPTION/EXPRESSION OF siRNA, AND USE THEREOF |
| 06/24/2010 | WO2010071190A1 Heparin affinity erythropoietin |
| 06/24/2010 | WO2010071147A1 Method for detecting controls for nucleic acid amplification, and use thereof |
| 06/24/2010 | WO2010071114A1 Method for detecting cancer cells in blood sample |