Patents
Patents for C07K 5 - Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof (30,692)
04/1989
04/18/1989US4822775 Phenyl substituted dipeptide amides
04/18/1989US4822635 Sweetening with L-aminodicarboxylic acid esters
04/18/1989CA1252949A1 Retro-inverso analogues of the bradykinin potentiating peptide bpp in5a xx and method for their preparation
04/12/1989EP0311057A2 Process for the production of glutamine derivatives
04/12/1989EP0310918A2 Peptide-like amino-acid derivatives
04/11/1989US4820861 Reacting l-phenylaline methyl ester and n-formyl-l-aspartic acid anhydride; sweeteners
04/11/1989US4820834 Gastrin, cholecystokinin antagonists
04/11/1989US4820729 Hypotensive agents
04/11/1989US4820691 Hypotensive agents
04/05/1989EP0310238A2 New physiologically active substances, probestin and prostatin and production thereof
04/05/1989EP0310015A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use
04/05/1989EP0309983A2 Enzymatic process for peptide preparation, in particular of dipeptides, and device therefor
04/05/1989EP0309971A2 New spergualin-related compound and pharmaceutical composition
04/05/1989EP0309841A2 Amino acid derivatives
04/04/1989US4818749 Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure
04/04/1989US4818748 Renin inhibitors and aminoacid and aminoaldehyde derivatives
04/04/1989US4818683 Radioactive material or enzyme tracer
03/1989
03/29/1989EP0309324A1 Process for the preparation of N-alkylated amino acids and their esters, use in the synthesis of carboxyalkyl dipeptides
03/29/1989EP0308885A1 Derivatives of d-glutamic acid and d-aspartic acid
03/28/1989US4816562 Novel substrate for plasma kallikrein and a method for measuring biological components using the same
03/28/1989US4816560 Storage stability
03/28/1989US4816485 N-phenylbenzamide derivatives
03/28/1989US4816482 Radioprotective agents having an amino-thioalkyl structure
03/28/1989US4816466 Piperidine derivatives
03/28/1989US4816449 Immunotherapeutic anti-inflammatory peptide agents
03/28/1989US4816444 Cell growth inhibitory substance
03/28/1989CA1251898A1 Pharmaceutical peptides, their preparation and use
03/28/1989CA1251802A1 Oxa-fenchols and oxa-fenchyl amines useful for preparing high intensity sweeteners
03/23/1989WO1989002456A1 Refrigerant
03/23/1989WO1989002431A1 Derivatives of d-glutamic acid and d-aspartic acid
03/23/1989DE3830825A1 Hydrophilic renin inhibitors, their preparation and use
03/22/1989EP0308341A1 Process for the industrial synthesis of perindopril and for its principal synthesis intermediates
03/22/1989EP0308340A1 Process for the synthesis of N-alkylated alpha-amino acids and their esters, use in the synthesis of carboxyalkyl dipeptides
03/22/1989EP0308339A1 Process for the industrial preparation of perhydroindole -2(2S,3aS,7aS)-carboxylic acid, use in the preparation of carboxyalkyl dipeptides
03/22/1989EP0308337A2 4-Aminopyridine derivatives and their acid addition salts
03/22/1989EP0308319A2 4-Piperidinecarboxamide derivatives
03/22/1989EP0307872A2 Esters of amino-acids, process for their preparation, medicaments containing them and their use
03/22/1989EP0307837A2 Renin-inhibiting peptidyl heterocycles
03/22/1989EP0307496A1 Process for the production of N-formyl-aspartyl-phenylalanine or its methyl ester
03/21/1989US4814485 4-aminobutanoic acid derivatives, process of preparation and use thereof
03/21/1989US4814463 CCK antagonists
03/21/1989US4814342 Nor-statine and nor-cyclostatine polypeptides
03/21/1989CA1251453A1 Bifunctional chelating agents
03/14/1989US4812555 Peptides possessing renin inhibitory activity
03/14/1989US4812442 Tripeptide renin inhibitors
03/09/1989WO1989001930A1 Pharmaceutical compositions for the treatment of psoriasis
03/09/1989WO1989001778A1 Agents for prophylaxis and treatment of thrombopenia
03/09/1989DE3728917A1 Novel lipids containing an asymmetrically substituted disulphide bridge, processes for their preparation, and their use as medicaments
03/08/1989EP0305401A1 Combinations having synergistic growth hormone releasing activity and methods for use thereof.
03/07/1989US4810818 Process for producing alpha-aspartyl-l-phenylalanine methyl ester having an improved solubility
03/07/1989US4810817 Artificial sweeteners
03/07/1989US4810816 Dehydroation of aspartic acid
03/07/1989US4810693 Copper derivative of oligopeptide
03/07/1989CA1251000A1 Dipeptides, process for the preparation thereof and pharcameutical preparations containing them
03/01/1989EP0305297A1 Derivatives of aza-z-bicyclooctane-caboxylicacid-3, processes for their preparation and pharmaceutical compositions containing them
03/01/1989EP0304954A2 Cyclic dipeptide enantiomers
03/01/1989EP0228404B1 Pentapeptides with cell growth regulatory effects and a process for the preparation thereof
02/1989
02/28/1989US4808713 Anthypertensive pyridazo [1,2-a][1,2]diazepines
02/28/1989US4808573 Angiotensin converting enzyme inhibitors
02/28/1989US4808572 α-Hydroxy thioethers
02/23/1989WO1989001488A1 Renin inhibiting peptides with nonpeptide linkages
02/23/1989WO1989001487A1 Removal of n-terminal acylated amino acid residues from polypeptides
02/22/1989EP0303602A1 Enzymatic synthesis
02/21/1989US4806680 3-halovinylglycine antibacterial agents
02/21/1989US4806641 Salts of 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazine and amino compounds
02/21/1989US4806473 Using carboxypeptidase y to cleave protective groups; producing di-, tri- and tetrapeptides
02/21/1989CA1250400A1 Peptides having influence on memory processes, processes for producing them and pharmaceutical compositions containing them
02/21/1989CA1250399A1 Peptide synthesis process
02/21/1989CA1250398A1 Tri-tetra- and pentapeptides, their preparation, and pharmaceutical products containing same
02/15/1989EP0303434A1 Thiazolidine compounds
02/14/1989US4804782 Branched amides of L-aspartyl-D-amino acid dipeptides
02/14/1989US4804743 Proline-containing renin inhibitors
02/14/1989US4804676 Propioxatins a and b
02/14/1989CA1250091A1 Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions
02/14/1989CA1250090A1 Pharmaceutical composition having an excellent absorption property
02/14/1989CA1250089A1 PROCESS FOR PRODUCING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER OR ITS HYDROCHLORIDE
02/14/1989CA1249975A1 Non-radioactive biological probes
02/09/1989EP0204826A4 Heat stabilized peptide sweeteners.
02/09/1989DE3825242A1 Histidinylamino compounds substituted by sulphur-containing groups
02/08/1989EP0302478A1 Method for purifying a dipeptide ester
02/08/1989EP0302442A2 Vibriolysin coupling process
02/07/1989US4803300 Crystallization; sterioisomers
02/01/1989EP0301970A1 Method for dissolving arginineamides and pharmaceutical compositions containing them
02/01/1989EP0301639A2 Analogues of the bradykinin potentiating peptide BPP 5a and methods for their preparation
02/01/1989EP0301398A2 Process for producing N-[(4-hydroxy-pyrrolidin-2-on-1-yl)-acetyl]-glycinamide
02/01/1989CN1030766A Enkastine-glycopeptide of action having inhibitory encephalinase, process for preparing them and pharamaceutical use
01/1989
01/31/1989US4801732 Aspartame
01/31/1989US4801721 Stereospecific synthesis of carboxyalkyl peptides
01/31/1989US4801609 Mercapto-acylamino acid antihypertensives
01/31/1989US4801580 Peptide, process for preparation thereof and use thereof
01/31/1989US4801579 Nutrient solutions, water solubility
01/31/1989US4801575 Chimeric peptides for neuropeptide delivery through the blood-brain barrier
01/31/1989US4801534 Hydrolysis, oligopeptides, proteolytic enzymes, analyzing
01/31/1989CA1249699A1 Retro-inverso analogue of the (5-14) decapeptide of equine angiotensinogen, as a specific renin inhibitor with high resistance to enzymatic hydrolysis
01/31/1989CA1249698A1 Retro-inverso analogues of c-terminal penta and hexapeptides of substance p
01/26/1989WO1989000427A1 Pharmaceutical therapeutic use of a glutathione derivative
01/25/1989EP0300518A1 Guanidine compounds containing a tetraphenylborate-ion, process for obtaining these compounds and use of these compounds in peptide synthesis
01/25/1989EP0300450A2 Method for producing alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride
01/25/1989EP0300287A2 Process for the reduction of ketones
01/25/1989EP0300001A1 Aminoluciferines, process for producing same and use thereof.