Patents
Patents for C07K 5 - Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof (30,692)
02/2005
02/02/2005EP1280818B1 Synthesis of n- [n-(3,3-dimethylbutyl)-l-alpha-aspartyl]-l-phenylalanine 1-methyl ester using l-alpha-aspartyl-l-phenylalanine 1-methyl ester precursors
02/02/2005EP0828754B1 Dipeptides which promote release of growth hormone
02/02/2005CN1575299A Homing peptides
02/02/2005CN1575169A Mch antagonists for the treatment of obesity
02/02/2005CN1572318A Composition containing dipeptide of histidine and alanine for reducing uric acid
02/02/2005CN1187361C Phosphoric-acid substituted benzo-aza-tropone-N-acetic acid derivative, preparing method and medicine thereof
02/01/2005US6849712 Includes a C-terminal aromatic amino acid residue and an amino acid residue having a lipophilic alkyl side chain as the penultimate C-terminal residue
02/01/2005US6849593 Bifidogenic peptides
01/2005
01/27/2005WO2005007831A2 Compositions of protein mimetics and methods of using same against hiv-1, sars-cov and the like
01/27/2005WO2005007654A1 Peptido-mimetic compounds containing rgd sequence useful as integrin inhibitors; and intermediates thereof
01/27/2005WO2005007079A2 Inactivators and bivalent inhibitors of glyoxalase i and methods of inhibiting tumor growth
01/27/2005WO2004065411A3 Peptides
01/27/2005WO2004050851A3 Prion protein ligands and methods of use
01/27/2005US20050020504 C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
01/27/2005US20050020503 Hepatitis C inhibitor compounds
01/27/2005US20050019826 Peptides blocking vascular endothelial growth factor(vegf)-mediated angiogenesis, polynucleotides encoding said pepetides and methods of use thereof
01/27/2005US20050019341 Gene that codes tumor antigen is detected by cytotoxic lymphocyte; isolated from Dna libraries
01/27/2005CA2532664A1 Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
01/27/2005CA2532013A1 Peptido-mimetic compounds containing rgd sequence useful as integrin inhibitors; and intermediates thereof
01/27/2005CA2528383A1 Inactivators and bivalent inhibitors of glyoxalase i and methods of inhibiting tumor growth
01/26/2005EP1500662A2 Stabilizing peptides
01/26/2005EP1499898A2 Regulation of tnf-alpha
01/26/2005EP1499636A2 Neurotrophic and neuroprotective peptides
01/26/2005EP1499336A2 Protease inhibitors
01/26/2005EP0871486B1 Diphtheria toxin epitopes
01/26/2005EP0579758B1 Parathyroid hormone receptor and dna encoding same
01/26/2005CN1571796A Melanocortin receptor ligands
01/25/2005US6846954 α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
01/25/2005US6846925 Colchinol derivatives as angiogenesis inhibitors
01/25/2005US6846806 Peptide inhibitors of Hepatitis C virus NS3 protein
01/25/2005US6846805 Oligopeptides or polypeptides used to inhibit transmembrane proteases such as aspartyl secretases, administered for prophylaxis of neurodegenerative diseases; Alzheimer's disease
01/25/2005US6846802 Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties
01/20/2005WO2005005468A1 Novel hcv core+1 protein, methods for diagnosis of hcv infections, prophylaxis, and for screening of anti-hcv agents
01/20/2005WO2005005461A2 Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof
01/20/2005WO2005005374A1 Aspartyl protease inhibitors
01/20/2005US20050014972 Novel intermediate for sweetener with high sweetness and process for producing the same
01/20/2005US20050014967 Artificial sweetener; hydrogenation of aspartame forming neotame
01/20/2005US20050014700 Cbi analogues of cc-1065 and the duocarmycins
01/20/2005US20050013826 Administering modified protein having disruptive element located in internal region; enhancing ubiquitin proteasome system degradation; effective, long term T cell response
01/20/2005CA2531222A1 Novel hcv core+1 protein, methods for diagnosis of hcv infections, prophylaxis, and for screening of anti-hcv agents
01/20/2005CA2529739A1 Aspartyl protease inhibitors
01/20/2005CA2525091A1 Water-soluble shps as novel alkylating agents
01/19/2005EP1498421A1 Gamma-secretase inhibitors
01/19/2005EP1497450A2 Methods for identifying compounds that modulate enzymatic activity
01/19/2005EP1497317A2 Dipeptidic growth hormone secretagogues
01/19/2005EP1497316A2 Growth hormone secretagogues
01/19/2005EP1497283A1 Maleic acid salt of(2s)-n-(5(amino(imino)methyl)-2-thienyl)methyl-1-(2r)-2-((2r)-2-((carboxymethyl)amino)3,3-diphenylpropanoyl)-2-pyrrolidine carboxamide and a process for
01/19/2005EP1497282A2 Inhibitors of serine protease, particularly hepatitis c virus ns3-ns4 protease
01/19/2005EP1496878A1 Methods for identification of modulators of angiogenesis, compounds discovered thereby, and methods of treatment using the compounds
01/19/2005EP1496877A2 Method and composition for treatment of diabetes, hypertension, chronic heart failure and fluid retentive states
01/19/2005EP1379283A4 Identification of target-specific folding sites in peptides and proteins
01/19/2005EP1287018B1 Thrombin inhibitors
01/19/2005CN1566141A Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof
01/19/2005CN1566058A Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof
01/19/2005CN1565627A Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
01/19/2005CN1185250C Compounds which inhibit leukocyte adhesion mediated by VLA-4
01/19/2005CN1185008C Therapeutic compositions containing glutathione analogs
01/18/2005US6844465 Method for preparing highly stable crystals of aspartame derivative
01/18/2005US6844318 Peptidase-cleavable, targeted antineoplastic drugs and their therapeutic use
01/18/2005US6844316 N-dipeptidoyl-O-acylhydroxyamines; suicide inhibitors which deactivate the DP I by the reaction with the nucleophilic active site thiol residue.
01/18/2005US6844315 Determining peptide's therapeutic effect by administering to subject prone to showing signs of diabetes; determining development of diabetes
01/18/2005US6844181 Method of inhibiting fungal growth
01/18/2005US6843989 Administering a CD40 binding protein that potentiates the binding of CD40 to CD40 ligand
01/18/2005CA2367127C Macrocyclic peptides active against the hepatitis c virus
01/18/2005CA2333686C Method and device for electrochemical immunoassay of multiple analytes
01/13/2005WO2005003166A1 Fluorescein-labelled peptides
01/13/2005WO2005003153A1 Novel method of synthesising perindopril and the pharmaceutically-acceptable salts thereof
01/13/2005WO2005003091A1 Novel method of synthesising (2s, 3as, 7as)-perhydroindole-2-carboxylic acid, and use thereof for synthesis of perindopril
01/13/2005WO2005002516A2 Leukocyte internalized peptide-drug conjugates
01/13/2005WO2005002508A2 Macromolecular platinum chelates
01/13/2005WO2004086039A3 A method for modulating nod1 activity, use of a mtp related molecule for modulating nod1 activity, and therapeutic applications thereof
01/13/2005US20050010060 Novel quinones as disease therapies
01/13/2005US20050010056 Concentrating aqueous fractions of lisinopril by reverse osmosis
01/13/2005US20050009807 Preventing the deposits of amyloid protein, treating neurodegenerative disease, Alzheimer's disease and Down's Syndrome; {[carbamoyl]cycloalkyl}-N-(2-oxo-5-phenyl((S)-3H-benzo[f]1,4-diazepin-3-yl))- or (2-oxo-5-phenyl((S)-3H-benzo[f]1,4-diazepin-3-yl))-carboxamide
01/13/2005US20050009755 (74)(3S)-3-amino-1-(1-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-4-yl)-5-methyl-2-heptanone for example; cysteine protease inhibitors; treating bone resorption diseases such as osteoporosis
01/13/2005US20050009753 Oligopeptides containing glutamic acid, proline and one other peptide such as glutamic acid, phenylalanine, lysine, tyrosine or valine
01/13/2005US20050009752 Novel peptides and medicinal uses thereof
01/13/2005US20050009751 Pentapeptide compounds and uses related thereto
01/13/2005US20050009747 High purity lipopeptides
01/13/2005US20050009041 Peptide nucleic acids and synthetic procedures therefor
01/13/2005US20050008637 Cancer therapy; antiinflammatory agents; autoimmune disease
01/13/2005US20050008603 Comb polymers; increase blood biocompatibility to inserts; reduce thrombogenicity ; oligosaccharide or oligopeptide side chain on polyvinyl amide, polyvinyl alcohol, polylysine
01/13/2005CA2529555A1 Leukocyte internalized peptide-drug conjugates
01/12/2005EP1496124A1 Catalytically active recombinant memapsin and methods of use thereof
01/12/2005EP1495318A1 Method for detecting ligands and targets in a mixture
01/12/2005EP1495124A2 Smac-peptides as therapeutics against cancer and autoimmune diseases
01/12/2005EP1495054A2 Cell wall mannoproteins and active epitopes from candida albicans and antibodies recognizing them
01/12/2005EP1495044A1 Heterocyclic amides with alpha-4 integrin antagonist activity
01/12/2005EP1494701A2 Immunosuppressant compounds, methods and uses related thereto
01/12/2005EP1494695A1 Plasma protein-binding ligands
01/12/2005EP1143992B1 Therapeutic compositions containing glutathione analogs
01/12/2005EP0956029B1 Cyclic peptides having broad spectrum antimicrobial activity
01/11/2005US6841701 Inhibitors for the blood-clotting factor Xa
01/11/2005US6841532 Peptides and their use to ameliorate cell death
01/11/2005US6841530 Semi-synthetic studies toward didemnin analogues
01/11/2005US6841183 Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates
01/11/2005CA2337099C Enzymes for biopolymer production
01/11/2005CA2128711C Trypsin inhibitors
01/06/2005WO2005001023A2 Method and carrier complexes for delivering molecules to cells
01/06/2005WO2005000880A2 Cytotoxic depsipeptides