Patents
Patents for C07K 4 - Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof (2,102)
02/1999
02/23/1999US5874541 Immunoglobulin or fragment is modified such that heavy chain variable region have been replaced by specific sequence or amino acids of a heavy chain immunogloblin comprising two heavy polypeptide chain consisting of antigen binding site
02/09/1999US5869445 Methods for eliciting or enhancing reactivity to HER-2/neu protein
12/1998
12/23/1998EP0885904A1 Peptides as agonists and/or inhibitors of amyloid formation and/or cytotoxicity and their use against Alzheimer's disease, type II diabetes mellitus and spongiform encephalopathy
12/17/1998CA2240005A1 Peptides acting as agonists and inhibitors of amyloid formation and cytotoxicity for therapeutic use with alzeheimer's disease, type ii diabetes mellitus and spongiform encephalopathies
12/08/1998US5846538 Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the her-2/neu oncogene is associated
12/03/1998WO1998054577A1 Cyclic peptide libraries and methods of use thereof to identify binding motifs
12/03/1998CA2290993A1 Cyclic peptide libraries and methods of use thereof to identify binding motifs
11/1998
11/24/1998US5840526 Two heavy polypeptide chains with variable and constant regions including complete antigen binding sites; constant region lacks ch1 domain; increased ease of preparation by genetic engineering; medical diagnosis
11/24/1998US5840340 Oligopeptides with fragrance, cosmetics and dye
11/04/1998EP0875564A1 Biologically active extract from the leech 'Limnatis nilotica'
10/1998
10/20/1998US5824774 Chimeric isoprenoid synthases and uses thereof
10/20/1998US5824640 Substances of polypeptide nature useful in human therapy
09/1998
09/23/1998EP0865292A1 Compositions and methods for the prevention and treatment of oral mucositis
09/15/1998US5808029 Genetic engineering
09/11/1998CA2282827A1 Method of alleviating neuropathic pain
09/09/1998EP0862448A1 Fine tuned protegrins
09/01/1998US5801005 Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
09/01/1998US5800988 Cdna libraries with nucleotide sequences coded for immunoglobulins with polypeptide chains
08/1998
08/25/1998US5798444 Incorporating derivatives of 2,4,5-triaminopentanoic acid and aminoglutamic acid into peptide during solid phase synthesis
08/18/1998US5795736 Peptide amino acid sequences, replacements and expression vectors
07/1998
07/21/1998US5783433 Ion exchanging
07/07/1998US5776895 Compositions of G-CSF and TNF-BP for prophylaxis and treatment of septic shock
07/02/1998WO1998027805A1 Antimicrobial proteins
07/02/1998CA2274730A1 Antimicrobial proteins
07/01/1998CN1186517A Altered polypeptides with increased half-life
06/1998
06/16/1998US5766927 Stabilizing the protein by contacting the cell with a dipeptide having an n-terminal amino acid residue selected form the group consists of arginine, lysins and histidine
06/16/1998US5766850 Human β2 integrin α subunit
06/02/1998US5759808 Immunoglobulins devoid of light chains
05/1998
05/27/1998CN1183117A Intracelluar domain of the HER-2/neu protein for prevention or treatment of malignancies
05/12/1998US5750654 Leukaemia inhibitory factor
05/12/1998US5750503 Administering synergistic mixture of granulocyte colony stimulating factor (g-csf) and tumor necrosis factor binding protein (tnf-bp) lacking first domain of constant region of heavy chain of human immunoglobulin igg1 or igg3
05/07/1998WO1998009985A3 Anti-inflammatory peptides and uses thereof
04/1998
04/30/1998WO1998017301A1 Peptides for inhibiting retroviruses
04/30/1998CA2272601A1 Peptides for inhibiting retroviruses
03/1998
03/31/1998US5734011 Ligand precursors for incorporation into peptides
03/25/1998EP0830603A1 Compositions and methods of using terminally labeled peptides that bind mhc class i molecules
03/12/1998WO1998009985A2 Anti-inflammatory peptides and uses thereof
03/12/1998WO1998009984A1 Central nervous system-derived immune privilege factor and uses thereof
03/12/1998WO1997046259A3 Chimeric toxin for targeted therapy
03/12/1998CA2264959A1 Central nervous system-derived immune privilege factor and uses thereof
03/12/1998CA2264285A1 Anti-inflammatory peptides and uses thereof
03/10/1998US5726023 Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated
03/03/1998US5723504 Amadori reaction compounds and products, process for their manufacture, and their use as cytokine inducers
02/1998
02/12/1998WO1998005348A1 Peptides responsive to antibodies against a consensus peptide of the cs4-cfa/i family proteins
02/05/1998WO1998004278A2 Tetrapeptide derivatives of dolastatin as antitumor agents
02/04/1998EP0821732A1 Altered polypeptides with increased half-life
01/1998
01/14/1998EP0817846A1 Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
12/1997
12/24/1997CN1168699A Protein kinase NPK-llo
12/18/1997WO1997047644A1 T cell antigen receptor peptides
12/11/1997WO1997046259A2 Chimeric toxin for targeted therapy
12/03/1997EP0600866B1 Compositions and methods for identifying biologically active molecules
11/1997
11/06/1997WO1997035969A3 Peptide ligands of the urokinase receptor
10/1997
10/23/1997WO1997038703A1 Chimeric isoprenoid synthases and uses thereof
10/02/1997WO1997035969A2 Peptide ligands of the urokinase receptor
09/1997
09/16/1997US5667811 Na-K-ATPase inhibiting natriuretic substances
08/1997
08/27/1997EP0791067A2 Protein kinase npk-110
08/20/1997CN1157620A Corticotropin-releasing factor-binding-protein inhibitors and their use
07/1997
07/23/1997EP0662135B1 Alteration of polypeptides
07/15/1997CA2063400C Inhibition of the n-end rule pathway in living cells
06/1997
06/24/1997US5641485 Caledothricins used in the treatment mycotic diseases
06/03/1997US5635484 Propionibacteria peptide microcin
05/1997
05/29/1997WO1997018827A1 Compositions and methods for the prevention and treatment of oral mucositis
05/29/1997CA2238429A1 Compositions and methods for the prevention and treatment of oral mucositis
05/13/1997US5628979 Reagent for tumor imaging and therapy
05/07/1997EP0771323A1 Corticotropin-releasing factor-binding-protein inhibitors and their use
05/02/1997EP0770091A1 Compounds for reversing drug resistance
04/1997
04/22/1997US5622933 Multiple branch peptide constructions for use against HIV
03/1997
03/25/1997CA1339015C Macrocyclic chelates and methods of use thereof
03/18/1997US5612042 Vaccine against streptococcus suis infection
03/11/1997US5610279 Human TNF receptor
02/1997
02/26/1997EP0697884A4 Ligand precursors for incorporation into peptides
02/12/1997CN1142503A Preparation of natural medical polymer materials
02/05/1997CN1142230A Antibiotic stalobacins
02/05/1997CN1033976C Preparation of polypeptides used as blockers of calcium channels
02/04/1997CA2071425C Prophylactic/therapeutic composition for disseminated intravascular coagulation, or chronic respiratory tract infectious disease
01/1997
01/03/1997WO1997000081A1 A method for inhibiting bacteremia and bacterial dissemination
01/03/1997CA2361012A1 Conformationally-restricted combinatorial library composition and method
12/1996
12/19/1996WO1996041188A1 Compositions and methods of using terminally labeled peptides that bind mhc class i molecules
12/18/1996EP0748335A1 Antibiotic stalobacins
12/10/1996US5583200 Containing magnesium or calcium ions; storage stability; immunoassay for myocardial infarction
12/03/1996CA2115461C Enzymatic analysis using substrates that yield fluorescent precipitates
11/1996
11/26/1996US5578323 Proteinoid carriers and methods for preparation and use thereof
11/06/1996CN1135237A Products that elicit neutralizing antibodies against genetically divergent HIV-1 strains
11/05/1996US5571701 Antibiotic, balhimycin, a process for its production and its use as pharmaceutical
10/1996
10/23/1996EP0641351B1 Enzymatic analysis using substrates that yield fluorescent precipitates
10/17/1996WO1996032478A1 Altered polypeptides with increased half-life
10/03/1996WO1996030514A1 Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
09/1996
09/24/1996CA2026418C Polypeptides useful as blockers of calcium channels
09/10/1996US5554375 Hair growth
09/04/1996CN1130028A Method for preparing phycocyan
08/1996
08/20/1996US5547846 Immunogenic regions on the E7 protein of human papillomavirus type 16
08/15/1996WO1996013590A3 New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
08/14/1996EP0725825A1 Peptides that elicit neutralizing antibodies against genetically divergent hiv-1 strains
08/01/1996WO1996013592A3 Protein kinase npk-110
07/1996
07/17/1996EP0721464A1 Neuron regulatory factor for promoting neuron survival
07/02/1996US5532339 Fusion protein between human macif and a heterologous pi anchor domain
05/1996
05/29/1996CN1031892C Expression of human proapolipoprotein A-I
05/09/1996WO1996013592A2 Protein kinase npk-110
05/09/1996WO1996013590A2 New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
05/09/1996CA2203910A1 Novel protein kinase (npk-110)
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