Patents
Patents for C07K 16 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies (149,320)
01/2004
01/08/2004US20040005328 Novel antigens of B. catarrhalis are provided, together with their use in vaccines as well as methods of diagnosing and/or detection. Branhamella catarrhalis (also known as Moraxella catarrhalis) is a gram-negative aerobic bacterium that causes
01/08/2004US20040005324 Identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV-binding ability, chimeric antibodies
01/08/2004US20040005323 Efficient method for generating human antibodies in particular which are specific to be RSV fusion protein which combines in vitro primary of human spleen cells and antigen boosting in SCID mice is taught. This method provides for very high human
01/08/2004US20040005322 Compositions and methods related to TIM-3, a Th1-specific cell surface molecule
01/08/2004US20040005321 Use of anti-ceacam antibodies for stimulating b cells in the production of monoclonal antibodies or in immunotheraphy
01/08/2004US20040005320 Treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Adult
01/08/2004US20040005318 Method of treatment using human sequence antibodies against human CTLA-4. In particular, methods of treating cancer are provided.
01/08/2004US20040005317 Methods of therapy and diagnosis using immunotargeting of CD84Hy1-expressing cells
01/08/2004US20040005316 Use of HMG fragments as anti-inflammatory agents
01/08/2004US20040005315 Administering an immunosuppressive agent that depletes T cells and anti-alpha beta T cell receptor antibodies, and implanting an allograft into the recipient.
01/08/2004US20040005314 Apo-2l receptor agonist and cpt-11 synergism
01/08/2004US20040005313 Use of specified TCF target genes to identify drugs for the treatment of cancer, in particular colorectal cancer, in which TCF/beta-catenin/WNT signalling plays a central role
01/08/2004US20040005298 Compositions and methods for restoring immune responsiveness in patients with immunological defects
01/08/2004US20040005276 Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with porphyromonas gingivalis
01/08/2004DE10227155A1 Glucan mit TNFα -Ausschüttung induzierender Wirkung, Verfahren zu dessen Herstellung und dieses enthaltende pharmazeutische Zubereitungen Glucan with TNF.alpha -Ausschüttung inducing activity, to processes for its preparation and pharmaceutical compositions containing this
01/08/2004CA2844639A1 Method for the treatment of multiple sclerosis
01/08/2004CA2542171A1 Modulators and modulation of the interaction between rgm and neogenin
01/08/2004CA2492092A1 Immunoglobin single variant antigen-binding domains and dual-specific constructs
01/08/2004CA2492057A1 Co-administration of cg250 and il-2 or ifn-alpha for treating cancer such as renal cell carcinomas
01/08/2004CA2491861A1 Human igm antibody lysing activated lymphocytes under mediation by homologous complement
01/08/2004CA2491859A1 Human igm antibody inducing apoptosis in hiv-infected cells and remedy for hiv-infection
01/08/2004CA2491480A1 Humanized anti-lymphotoxin beta receptor antibodies
01/08/2004CA2491427A1 Compositions and methods for therapeutic treatment
01/08/2004CA2491363A1 Antibodies and uses thereof
01/08/2004CA2491094A1 Method for determination of likelihood of occurrence of preterm labor in pregnant females
01/08/2004CA2491053A1 Use of antibodies against flt-1 for the treatment of osteoporosis
01/08/2004CA2490804A1 Method of treating autoimmune diseases with interferon-beta and il-2r antagonist
01/08/2004CA2490659A1 Humanized anti-tag-72 cc49 for diagnosis and therapy of human tumors
01/08/2004CA2490411A1 Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
01/08/2004CA2490409A1 Mammalian ch1 deleted mimetibodies, compositions, methods and uses
01/08/2004CA2490280A1 Antibodies that specifically bind to reg iv
01/08/2004CA2490261A1 Differentiation modulating agents and uses therefor
01/08/2004CA2490186A1 Method for the treatment of multiple sclerosis
01/08/2004CA2489515A1 Methods and compositions for modulating and detecting wisp activity
01/08/2004CA2486543A1 Pesticidally active proteins and polynucleotides obtainable from paenibacillus species
01/07/2004EP1378570A1 Flk-1 is a receptor for vascular endothelial growth factor
01/07/2004EP1378525A2 Humanized antibodies that bind to the antigen bound by antibody NR-LU-13 and their use in pretargeting methods
01/07/2004EP1378524A2 Recombinant thrombin receptor antibodies and their use
01/07/2004EP1378523A1 Anti-cd30 antibodies and uses thereof
01/07/2004EP1378521A1 Anti-Carbohydrate Deficient Transferrin (CDT) spezific antibody, its production and use
01/07/2004EP1378520A1 Cyclic single strand trispecific antibody
01/07/2004EP1378245A2 Transferrin binding proteins from neisseria gonorrhoeae and neisseria meningitidis. Their use in a vaccine
01/07/2004EP1377833A2 Gastrointestinal glutathione peroxidase in hepatitis c virus infections
01/07/2004EP1377832A2 Anti-idiotypic antibody and its use in diagnosis and therapy of hepatitis c virus related diseases
01/07/2004EP1377664A2 Genes encoding proteolytic enzymes from aspargilli
01/07/2004EP1377663A2 Intermediates and enzymes of the non-mevalonate isoprenoid pathway
01/07/2004EP1377611A2 Muteins of hypoxia inducible factor alpha and methods of use thereof
01/07/2004EP1377607A2 Nucleic acid sequences of hyperplasies and tumors of the thyroid
01/07/2004EP1377314A2 Monoclonal antibodies to the clfa protein and method of use in treating or preventing infections
01/07/2004EP1377311A2 Treatment of neuropathologies associated with expression of tnf-alpha
01/07/2004EP1377307A2 Anti-gpe antibodies, their uses, and analytical methods for gpe
01/07/2004EP1377165A2 Tsg101-gag interaction and use thereof
01/07/2004EP1034187B1 Growth-promoting proteins and peptides for kidney epithelial cells
01/07/2004EP0647270B1 Novel malignant cell type markers of the interior nuclear matrix
01/07/2004CN1466464A Novel remedies for cancer
01/07/2004CN1465696A Polypeptide-trorsine 14 and polynucleotide for coding said polypeptide
01/07/2004CN1465596A Establishment of recombination human bone morphogenetic protein-2 microimmunication and antibody preparation thereof
01/07/2004CN1465595A Mouse histone human endostatin monoclone antibody
01/07/2004CN1465589A Gene recombination SARS virus coat protein S and preparation process thereof
01/07/2004CN1465587A Polypeptide-chondriosome carrier 18 and polynucleotide for colding said polypeptide
01/06/2004US6673986 Transgenic mouse; deactivated endogenous immunoglobulin heavy chain loci; gene expression
01/06/2004US6673916 Phospholipase inhibitors
01/06/2004US6673903 Antiproliferative agents
01/06/2004US6673901 Fibronectins for use as diagnostic and treatment tools in gene therapy
01/06/2004US6673899 Protein for use treatment of diabetes
01/06/2004US6673898 Estrone sulfate, dehydroepiandrosterone sulfate and/or ochratoxin a; genetically engineered mutant
01/06/2004US6673896 Derivatives of soluble T-4
01/06/2004US6673895 Pro-apoptotic fragments of the dengue virus envelope glycoproteins
01/06/2004US6673580 Genetically engineering thrombopoietin for use in the treatment of thrombocytopenia; obtain polypeptide, adjust epitopes, recover polypeptide, administer to patients
01/06/2004US6673561 Use in monitoring the treatment of blood disorders in a patient by monitoring changes in the levels of fibrinopeptide b (fpb) in the patient's urine
01/06/2004US6673559 Met proto-oncogene and a method for predicting breast cancer progression
01/06/2004US6673534 Methods for detection of mutations in myostatin variants
01/06/2004US6673355 Administering vaccine to pregnant women; prevention and diagnosis of gastroenteritis, cystic fibrosis, and diarrhea
01/06/2004US6673348 Heat shock protein-based vaccines and immunotherapies
01/06/2004US6673347 Conjugated to polymer via schiff base, hydrazone, oxime, or azomethine compound; diagnosing tumors and metastasis
01/06/2004US6673346 Compositions and methods for the treatment of sepsis
01/06/2004US6673344 Antibodies to human CKβ-10/MCP-4
01/06/2004US6673343 Useful for activating their respective receptor and thereby enabling the role of tyrosine kinase receptor in cell growth and/or differentiation to be studied
01/06/2004US6673342 Administering dimeric or polymeric iga antibodies that are for useful in preventing or inhibiting infection by pathogens
01/06/2004US6673341 Inhibiting transforming growth factor (tgf-beta) mediated angiogenesis, thereby inhibiting the proliferative disease in vertebrate
01/06/2004CA2135083C Antibodies to p-selectin and their uses
01/06/2004CA2128208C Novel seven transmembrane receptors
01/06/2004CA2086681C Growth promoting agent derived from milk
01/06/2004CA2047721C Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
01/05/2004CA2432942A1 Carbohydrate deficient transferrin (cdt)-specific antibodies, their preparation and use
01/02/2004EP1375662A1 A novel polypeptide compose substance for promoting blood and blood vessel cell growth
01/02/2004EP1375520A1 Apoptosis induced by monoclonal antibody anti-Her2
01/02/2004EP1375519A2 Method for affecting cellular function using antibodies
01/02/2004EP1375518A1 Anti-osteopontin antibody and use thereof
01/02/2004EP1375516A2 Method of production of a recombinant polypeptide of the LSR receptor
01/02/2004EP1374902A1 Remedies for inflammatory bowel diseases
01/02/2004EP1374901A1 Graft rejection suppressors
01/02/2004EP1374900A1 Remedies for infant chronic arthritis-relating diseases
01/02/2004EP1374896A1 Blood rheology improving agents
01/02/2004EP1374895A2 Pharmaceutical composition of f(ab) 2 fragments of antibodies and method for the preparation thereof
01/02/2004EP1374862A2 Use of a substance influencing the degree of phosphorylation of BAD for the treatment of atherosclerosis
01/02/2004EP1373905A2 Method for detecting chronic dementia diseases, and corresponding peptides and detection reagents
01/02/2004EP1373547A1 Control of glycoforms in igg
01/02/2004EP1373519A2 New elongase gene and production of delta-9-polyunsaturated fatty acids
01/02/2004EP1373517A2 Human kinases