Patents
Patents for C07K 16 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies (149,320)
12/2004
12/16/2004WO2004081198A3 Methods for modulating angiogenesis with apelin compositions
12/16/2004WO2004065417A3 Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
12/16/2004WO2004062602A3 Compositions and methods for targeted biological delivery of molecular carriers
12/16/2004WO2004032838A3 Methods for treating cancer by inhibiting wnt signaling
12/16/2004WO2004022697A3 Denaturat stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof
12/16/2004WO2004010951A3 Method of treating tumors
12/16/2004WO2003104434A3 A method to amplify variable sequences without imposing primer sequences
12/16/2004WO2003090514A8 Adipocyte complement related protein zacrp14
12/16/2004WO2003057833A3 Mutant chromophores/fluorophores and methods for making and using the same
12/16/2004WO2003000176A8 Conjugates of reduced antibodies and biomolecules
12/16/2004US20040254363 Genes and snps associated with eating disorders
12/16/2004US20040254362 Nucleotide sequences coding polypeptide associate with fatty acid metabolism for use in diagnosis, prevention and treatment of obesity, diabetes and heart disease
12/16/2004US20040254361 Gene encoding protein from merozoite of Babesia caballi, recombinant protein obtained with said gene and use thereof
12/16/2004US20040254350 Immunomodulatory protein for use in diagnosis, treatment, and prevention of immune system, neurological, developmental, muscle and cell proliferative disorders
12/16/2004US20040254349 Mycobacterial antigens expressed under low oxygen tension
12/16/2004US20040254348 Opiate receptor therapeutic protein/peptides for use in pain relief and management
12/16/2004US20040254346 Human survivin interacting protein 1 (sip-1)
12/16/2004US20040254144 Use of inhibitors of heparin-binding epidermal growth factor or inhibitors of its receptors for the preparation of drugs useful for treating myeloma
12/16/2004US20040254116 Contactor tissue with transforming growth factor kinase receptors; modulate cell proliferation
12/16/2004US20040254111 Regulator of apoptosis and cell proliferation
12/16/2004US20040254108 Preparation and application of anti-tumor bifunctional fusion proteins
12/16/2004US20040253711 Mycobacterial genes down-regulated during latency
12/16/2004US20040253709 Schistosoma protein for use in treatment of organ-specific autoimmune diseases
12/16/2004US20040253698 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
12/16/2004US20040253684 Nucleotide sequences coding mambrane associated guanylate kinase for use in treatment and prevention of nervous system, blood, sleep and behavioral disorders
12/16/2004US20040253682 Immunloglobulin prostaglandin inhibitor for use in the treatment and prevention of arthritic and inflammatory bowel disorders
12/16/2004US20040253681 Mitogenic oxygenase regulators
12/16/2004US20040253674 Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
12/16/2004US20040253673 Recombinant botulinum toxins with a soluble C-terminal portion
12/16/2004US20040253667 Expression vector comprising nuclelotide sequences coding membrane protein for use in identifying modulator for treatment of cell proliferative, nervous system and inflammatory diseases
12/16/2004US20040253666 Secreted and transmembrane polypeptides and nucleic acids encoding the same
12/16/2004US20040253655 Immunoassay for use in detection high blood pressure; immunodiagnostics
12/16/2004US20040253653 Monoclonal antibody for use in diagnosis, prevention and treatment of cell proliferative disorders; antitumor agents; immunotherapy
12/16/2004US20040253645 Monoclonal antibody with enhanced species preference; immunotherapy
12/16/2004US20040253643 Using ratio of neurofibrillary tangle to amyloid beta protein in cerebrospinal fluid as diagnostic indicator of nervous system disorders; immunodiagnostics
12/16/2004US20040253638 Immunoglobulins devoid of light chains
12/16/2004US20040253611 Immunologically active proteins from borrelia burgdorferi
12/16/2004US20040253610 Expression vector comprising nucleotide sequences coding tumor necrosis factor receptor protein (TWEAK) for use in identifying modulators for treatment of inflammatory, cardiovacullar, vision and cancer disorders
12/16/2004US20040253595 P53-dependent apoptosis-inducing protein and method of screening for apoptosis regulator
12/16/2004US20040253588 Cytochrome p450 monooxygenase for use in identifying modulators for treatment, diagnosis and prevention of autoimmune/inflammatory, cell proliferative, developmental, endocrine, eye, metabolic, gastrointestinal and liver disorders
12/16/2004US20040253587 Antagonists of interleukin-15
12/16/2004US20040253580 Nucleotide sequences coding viral protein for use in treatment and prevention of viral disease in fish; veterinary medicine
12/16/2004US20040253250 Compositions and methods for regulating lymphocyte activation
12/16/2004US20040253247 Conjugate comprising a peptide having an engineered amino acid sequence capable of binding a plasma protein, said peptide conjugated to the therapeutic or diagnostic substance, wherein elimination half time of conjugate exceeds that of unconjugated therapeutic or diagnostic substance; peptide ligands
12/16/2004US20040253246 isolated nucleic acid (DNA, cDNA, or RNA); an expression vector; host cell expressing the vector; a polypeptide; detecting hematogenous micrometastic tumor cells; determining prostate cancer progression
12/16/2004US20040253244 Methods for treating pain by administering a nerve growth factor antagonist and an NSAID and compositions containing the same
12/16/2004US20040253242 immunoglobulins or fragments comprising complementarity determining regions (CDR) having segments replaced with human brain natriuretic peptides, glucagon-like peptides, exendins, glucagons, pituitary adenylate cyclase-activating polypeptides and/or mimetics; immunotherapy
12/16/2004US20040253241 Inducible ligand for alpha1beta1 integrin and uses
12/16/2004US20040253240 immunogens used to induce immune response against specific epitopes of apolipoproteins; prophylaxis of atherosclerosis; immunotherapy
12/16/2004US20040253238 Modified antibody
12/16/2004US20040253237 Methods of treatment of ulcerative colitis with anti-CD3 antibodies
12/16/2004US20040253236 Glycoprotein VI and uses thereof
12/16/2004US20040253235 administering interferon-beta (IFN- beta) receptor agonist and tumor associated antigen to increase an immune response against the tumor cells
12/16/2004US20040253234 DNA sequences that code antibodies or fragments; genetic vectors and host cells transformed by the vector, used for diagnosis and prophylaxis of cancer
12/16/2004US20040253233 genetic engineered chimeric and humanized antibodies obtained from murine monoclonal antibody P3 (MAb P3) and its antiidiotypic antibodies, used as antitumor agents
12/16/2004US20040253232 monoclonal antibodies or antigen binding fragments that specifically to six transmembrane epithelial antigens of the prostate (STEAP-1), used for medical diagnosis, prognosis, prophylaxis and/or therapy for cancers
12/16/2004US20040253231 monoclonal or polyclonal antibodies having specific reactivity with adenosine triphosphate binding domains, caspase recruitment domains and triosephosphate isomerase domain peptides, used for modulation of apoptosis
12/16/2004US20040253230 Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
12/16/2004US20040253229 administering a mixture of carriers and drugs that modulate signal transduction mediated by activation inducible lymphocyte immunomodulatory molecule (AILIM); immunosuppressants
12/16/2004US20040253222 transgenic neisseria having mutant phospholipase gene so that the bacteria has reduced phospholipase D activity as compared wild-type; polypeptide and polynucleotide, used for immunization of mammals against bacterial infections
12/16/2004CA2568806A1 Methods for detecting and treating cancer using podocalyxin and/or endoglycan
12/16/2004CA2531569A1 Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survivial of transplanted hematopoietic stemcell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transformation introducing the gene
12/16/2004CA2528851A1 Extracellular aspergillus polypeptides
12/16/2004CA2527728A1 Micropositioning cells for tissue engineering
12/16/2004CA2527726A1 De-immunized anti-cd3 antibody
12/16/2004CA2526669A1 Use of myostatin (gdf8) inhibitors in conjunction with corticosteroids for treating neuromuscular disorders
12/16/2004CA2526509A1 Connective tissue growth factor antibodies
12/16/2004CA2525975A1 Humanized antibodies that recognize beta amyloid peptide
12/16/2004CA2524329A1 Anti-hgf-r antibodies and their use
12/15/2004EP1486566A1 Proteins capable of binding to female sex hormones and process for producing the same
12/15/2004EP1486560A2 Specific antibodies and antibody fragments for TGFBETA1
12/15/2004EP1486508A1 Use of the AL-1 neurotrophic factor, a ligand for an EPH-related tyrosine kinase receptor, for the preparation of a medicament for modulating angiogenesis associated disease or condition
12/15/2004EP1485718A2 Method for monitoring collagen type ii degradation in cartilage
12/15/2004EP1485486A2 Optimizing glycan processing in plants
12/15/2004EP1485481A2 Fluorescent protein from aequorea coerulescens and uses thereof
12/15/2004EP1485480A2 Cd40 splice variants, method of detection thereof, compositions comprising said variant(s) or nucleic acid encoding the same and use thereof
12/15/2004EP1485477A2 Novel type-1 cytokine receptor glm-r
12/15/2004EP1485468A2 Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
12/15/2004EP1485415A2 Neoplasm specific antibodies and uses thereof
12/15/2004EP1485414A2 A multifunctional complex for targeting specific phagocytosis of a target agent
12/15/2004EP1485412A1 Repressor of skeletal muscle differentiation, nucleic acids coding therefor and the use thereof in diagnosis and therapy
12/15/2004EP1485410A1 Diagnostic and therapeutic use of human maguin proteins and nucleic acids for neurodegenerative diseases
12/15/2004EP1485407A1 A mutated immunoglobulin-binding protein
12/15/2004EP1485130A2 Reagents and treatment methods for autoimmune diseases
12/15/2004EP1485129A2 Nanostructures containing pilin protein
12/15/2004EP1485128A2 Nanostructures containing antibody assembly units
12/15/2004EP1485127A2 Administration of agents for the treatment of inflammation
12/15/2004EP1485126A2 Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
12/15/2004EP1485122A2 Novel application of vaccination against tnf-alpha
12/15/2004EP1485075A2 Mhc-peptide complex binding ligands
12/15/2004EP1263779B1 Self antigen vaccines for treating b cell lymphomas and other cancers
12/15/2004EP1259248B1 Methods for treating cancers expressing vascular endothelial growth factor d
12/15/2004EP1121599B1 Detection and quantification of vancomycin in biological fluids
12/15/2004EP1116029A4 Apoptosis marker antibodies and methods of use
12/15/2004EP1073461B1 Viral chimeras comprised of caev and hiv-1 genetic elements
12/15/2004EP0968290B1 Anti-alphavbeta3 humanized monoclonal antibodies
12/15/2004EP0956304B1 Dendritic cell-specific antibodies
12/15/2004EP0932666B1 Map kinases: polypeptides, polynucleotides and uses thereof
12/15/2004EP0863204B1 Human cyclin i and gene encoding the same
12/15/2004CN1555415A Synthetic HCV envelope proteins and their use for vaccination