Patents
Patents for C07K 14 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof (291,526)
10/1999
10/26/1999US5972888 Lowering the production or release of neuropeptide y which comprises administering to a mammal in need thereof an effective amount of an isolated naturally occurring obesity protein, or a pharmaceutically acceptable salt thereof
10/26/1999US5972886 Amino acid sequences, a gene coding for stimulating cell differentiation of megakaryocytes; increasing blood platelet cells
10/26/1999US5972884 Morphogen treatment of gastrointestinal ulcers
10/26/1999US5972883 Vasoactive intestinal peptide; a polypeptide
10/26/1999US5972704 HIV nef targeted ribozymes
10/26/1999US5972702 There also exists a need to identify the gene(s) responsible for osteopetrosis and to provide a genetic therapy for treating osteopetrosis. an object of the invention is to provide compounds that desirably influence the bone remodeling
10/26/1999US5972699 Method and reagent for inhibiting herpes simplex virus replication
10/26/1999US5972698 Tryptase is expressed virtually exclusively by mast cells.
10/26/1999US5972688 HTm4 methods of treatment and assays, agonists and antagonists
10/26/1999US5972687 Toxin gene from Xenorhabdus nematophilus
10/26/1999US5972679 The identification and isolation of extracellular polypeptides which are associated with plant frost or cold tolerance and their use in mitigating the effects of frost and controlling crystalline growth of ice.
10/26/1999US5972674 May be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the nf-.kappa.b cascade.
10/26/1999US5972663 Microorganism strain that overexpresses a gene which encodes a protein directly suitable for secreting antibiotics, or other toxic substances, out of the cell, the strain also has deregulated metabolism for increased l-cysteine production
10/26/1999US5972659 Introducing into e. coli a heterologous plasmid expression vector coding for the tobacco mosaic virus protein coat and a pathogen's epitope, separating fusion protein and lowering ph to form a self-aggregated protein and hapten for vaccines
10/26/1999US5972658 DNA encoding lung growth factor variant
10/26/1999US5972657 Gene encoding outer membrane protein B1 of moraxella catarrhalis
10/26/1999US5972655 These transcription factors mediate extracellular signals that induce expression of genes involved in such diverse processes as cell division, inflammation, and apoptosis.
10/26/1999US5972654 The use of these sequences in the diagnosis, treatment, and prevention of developmental, reproductive, muscle, immunological, and neoplastic disorders.
10/26/1999US5972653 The use of these sequences in the diagnosis, prevention, and treatment of inflammation and disorders associated with cell proliferation and apoptosis.
10/26/1999US5972652 Polynucleotides encoding secreted proteins
10/26/1999US5972651 Polynucleotides and polypeptides of the fifty-four homologue family, (ffh); vectors and transformed host cells; ffh are components of protein secretory apparatus and their inhibition of function is deleterious to bacteria cells
10/26/1999US5972650 Can be used as vehicles for the delivery of nucleic acids that can serve as therapeutic agents and as part of vaccines designed to immunize people or animals against viral diseases.
10/26/1999US5972649 Polynucleotide sequence encoding human multiple endocrine neoplasia type 1 protein
10/26/1999US5972648 Hirudin analogs having val1-val2 of naturally-occurring hirudin substituted with ile1-ile2 are preferred for their high antithrombiin activity.
10/26/1999US5972646 Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-cis retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
10/26/1999US5972645 Flea serine protease nucleic acid molecules
10/26/1999US5972643 Isolated polynucleotide molecules encoding CTCF, a CCCTC-binding factor
10/26/1999US5972636 ATP-dependent protease and use of inhibitors for same in the treatment of cachexia and muscle wasting
10/26/1999US5972629 Immunoassay to generate patterns of reactivity, then comparing sample to known pattern; for noninvasive diagnosis
10/26/1999US5972625 Assays for inhibitors of leukocyte adhesion
10/26/1999US5972624 Method of identifying ligands which bind recombinant galanin receptor (GALR2)
10/26/1999US5972623 Collagen-peptide assay method
10/26/1999US5972621 Incubating a cell that expresses an obr protein encoded by an exogenous nucleic acid molecule in the presence and absence of a test compound; determining phosphorylation, identifying compounds that alter phosphorylation; obesity, cachexia
10/26/1999US5972609 Utrophin gene promotor
10/26/1999US5972601 Isolated polynucleotide molecules useful for analyzing alloantigen phenotypes, to peptides encoded by these molecules, and to the diagnostic and therapeutic uses thereof relating to the ?pen? human platelet polymorphism.
10/26/1999US5972600 Separation of active complexes
10/26/1999US5972599 High affinity nucleic acid ligands of cytokines
10/26/1999US5972597 Methods using modified vaccinia virus
10/26/1999US5972596 Nucleic acid constructs containing HIV genes with mutated inhibitory/instability regions and methods of using same
10/26/1999US5972353 Immunogenic amount of an immunologically active mn protein or m polypeptide effective to immunize a vertebrate against a neoplastic disease associated with expression of mn antigen
10/26/1999US5972352 Cloning of mite allergens
10/26/1999US5972351 Polypeptides; method of identifying peptides of an antigen of interest which are capable of recognition by or induction of cytotoxic t lymphocytes; vaccines, immunology
10/26/1999US5972349 Synthesis of polyribosylribitol phosphate oligosaccharides
10/26/1999US5972348 Nickel binding protein and its encoding dna isolated from helicobacter pylori; useful as vaccine, diagnostic, drug target, and therapy in itself
10/26/1999US5972347 Pharmaceutical composition containing a neutralized virus and use thereof
10/26/1999US5972338 ?tie? or ?tie? are acronyms, which stand for ?tyrosine kinase containing ig and egf homology domains?; present invention concerns novel human tie ligand homologues with powerful effects on vasculature; antitumor agents
10/26/1999US5972337 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
10/26/1999US5972336 Urease-based vaccine against helicobacter infection
10/26/1999US5972334 Vaccines for treatment of lymphoma and leukemia
10/26/1999US5972331 Crystalline interferon alpha for pulmonary delivery and method for producing the same
10/26/1999US5972308 Reacting technetium-99 with a cyclic oligopeptide having amino acid units containing a mercaptan group attached to the ring through a homocysteine unit.
10/26/1999CA2057536C Cloning and expression of borrelia lipoproteins
10/26/1999CA2011378C Achromobacter protease i gene and gene product thereof
10/26/1999CA1340805C Nucleotide sequence incoding plant ribosome inactivating protein
10/26/1999CA1340802C Senile amyloid precursor protein and an antibody specific for the same
10/21/1999WO1999053310A1 Antigen
10/21/1999WO1999053103A1 Diagnosis of multiple sclerosis and other demyelinating diseases
10/21/1999WO1999053099A1 Recombinant proteins of treponema pallidum and their use for a syphilis vaccine
10/21/1999WO1999053091A2 Dna coding for gdnf, parts of said dna and gdnf variants
10/21/1999WO1999053083A1 Seed specific polycomb group gene and methods of use for same
10/21/1999WO1999053082A2 Hexose carrier proteins
10/21/1999WO1999053080A1 Novel constructs for controlled expression of recombinant proteins in prokaryotic cells
10/21/1999WO1999053075A2 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants
10/21/1999WO1999053070A1 Flowering locus t (ft) and genetically modified plants having modulated flower development
10/21/1999WO1999053069A2 Cell cycle regulatory proteins cdc2 and pitslre from plants
10/21/1999WO1999053068A2 Sucrose transporters from plants
10/21/1999WO1999053067A2 Seed-coat promoters, genes and gene products
10/21/1999WO1999053066A1 U4, a member of the hematopoietin receptor superfamily
10/21/1999WO1999053065A1 Improved methods for making hormone heterodimers
10/21/1999WO1999053064A2 Methods of delivering glp-1
10/21/1999WO1999053062A2 Isolated sh3 genes associated with myeloproliferative disorders and leukemia, and uses thereof
10/21/1999WO1999053061A2 Tumor associated nucleic acids and uses therefor
10/21/1999WO1999053060A2 Glaucoma therapeutics and diagnostics based on a novel human transcription factor
10/21/1999WO1999053059A1 Secretion of glycosylated proteins using a tissue plasminogen activator pro-sequence
10/21/1999WO1999053058A1 Vertebrate patched-2 protein
10/21/1999WO1999053057A1 Protein and gene participating in the differentiation of immortalized cells
10/21/1999WO1999053056A1 Novel protein and processes for producing the same
10/21/1999WO1999053055A2 Therapeutic agent for ngf
10/21/1999WO1999053054A1 Axor4 g-protein-coupled receptor
10/21/1999WO1999053053A1 Gene coding for heliomicine and use thereof
10/21/1999WO1999053052A2 Srebp-2-deficient cell lines
10/21/1999WO1999053051A2 5' ests and encoded human proteins
10/21/1999WO1999053047A2 Porcine adenovirus type 3 genome
10/21/1999WO1999053046A2 Noncloning technique for expressing a gene of interest
10/21/1999WO1999053045A1 Secreted proteins and polynucleotides encoding them
10/21/1999WO1999053043A2 Herpes simplex virus latency associated transcript polypeptides
10/21/1999WO1999053042A2 Biological material with increased expression of endogenous complement regulatory molecules
10/21/1999WO1999053040A2 Human nucleic acid sequences from ovarian tumour tissue
10/21/1999WO1999053033A1 Methods and compositions for high yield production of eukaryotic proteins
10/21/1999WO1999053032A1 TRANSGENIC MAMMALS EXPRESSING MUTANT GP IIIa
10/21/1999WO1999053028A1 Pns cell lines and methods of use therefor
10/21/1999WO1999053021A1 Cell differentiation/proliferation and maintenance factor and uses thereof
10/21/1999WO1999053016A2 Expression of alfin1 and methods for producing transgenic plants having increased root growth and root specific gene activation
10/21/1999WO1999052988A1 Adhesives
10/21/1999WO1999052947A2 TRANSFERRIN RECEPTOR GENES OF $i(MORAXELLA)
10/21/1999WO1999052946A1 Method for sterilising native collagen in liquid medium, resulting native collagen, compositions containing same and uses
10/21/1999WO1999052945A2 NOVEL MOLECULES OF THE BGCKr-RELATED PROTEIN FAMILY AND USES THEREOF
10/21/1999WO1999052944A1 G-protein coupled receptors
10/21/1999WO1999052943A1 T cell receptor expression cassette
10/21/1999WO1999052942A2 Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma