Patents
Patents for C07K 14 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof (291,526)
12/2000
12/26/2000US6166288 Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
12/26/2000US6166287 Screening for modulators useful in the treatment of cushing's syndrome and anxiety; administering modulators to transgenic rodent, monitoring expression of protein in preferential hypothalmus cells, compare to wild-type expression
12/26/2000US6166200 Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
12/26/2000US6166195 Nucleotide sequences that encode a nematocide
12/26/2000US6166194 Nucleotide sequences coding cancer modulator protein; for gene therapy; antitumor agents
12/26/2000US6166193 Nucleotide sequence which encodes g-protein coupled receptor; for the treatment and prevention of bacterial, fungal, protozoan and viral infections; for use in gene therapy
12/26/2000US6166192 PGC-1, a novel brown fat PPARγ coactivator
12/26/2000US6166191 Nucleotide sequences coding cancer protein; for diagnosis and detection of cell proliferative and developmental defects
12/26/2000US6166190 Isolated nucleic acid molecule encoding human skeletal muscle-specific ubiquitin-conjugating enzyme
12/26/2000US6166186 Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma
12/26/2000US6166185 Antibodies to human TIE-2 ligands
12/26/2000US6166183 Chemically-modified G-CSF
12/26/2000US6166182 Polypeptides for the treatment of bacterial, fungal, protozoan and viral infections
12/26/2000US6166181 Mammalian binding protein; for the treatment of cardiovascular, kidney, brain, psychological and nervous system disorders; antihypoxic agents; hypotensive agents; antiischemic agents
12/26/2000US6166180 Polypeptide for the treatment of genetic disorders associated with transmembrane protein
12/26/2000US6166178 Polypeptide for the treatment of cancer; anticarcinogenic agents
12/26/2000US6166177 Compounds and methods for the treatment and diagnosis of chlamydial infection
12/26/2000US6166176 Cancer marker protein and peptides thereof
12/26/2000US6166090 Prevention atherosclerosis; administering transforming growth factor
12/26/2000US6165993 DNA vaccines against rotavirus infections
12/26/2000US6165992 Histidine kinase
12/26/2000US6165989 An isolated polynucleotide comprising a first polynucleotide or the full complement of the entire length of the first polynucleotide, wherein the first polynucleotide encodes a polypeptide comprising specific amino acid sequence
12/26/2000US6165981 Stabilizing solutions for proteins and peptides
12/26/2000US6165974 Administering an effective dose of a pharmaceutical preparation comprising at least two coagulation factors which are components of a prothrombinase or of a pro-prothrombinase to the patient for the treatment of acute bleeding
12/26/2000US6165793 Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
12/26/2000US6165792 Amino acid transporters
12/26/2000US6165787 Regulated transcription of targeted genes and other biological events
12/26/2000US6165783 Inducing the cellular differentiation of neuronal stem cells into neurons; incubating neuronal stem cells with glycoproteins and animal growth regulators and allowing stem cells to differentiate into neurons
12/26/2000US6165782 Nucleotide sequences for the transfer of heterologous nucleotide sequences to cells and biosynthesis of transcripts and heterologous proteins
12/26/2000US6165781 Nucleotide sequences comprising an inverted terminal duplication and heterologous nucleotide sequences; for the treatment of genetic disorders and gene therapy
12/26/2000US6165779 Recombinant virus vector such as tumor suppressor gene formulated in a buffer comprising a detergent; for gene therapy of cancer; buffer comprising a delivery-enhancing agent
12/26/2000US6165774 Culturing virus in cells, separating out virus, solubilizing hemagglutinin-neuramidase and fusion envelope glycoproteins from virus, and coisolating and copurifying using ion exchange chromatography and hydroxyapatite matrix
12/26/2000US6165767 Protein phosphatase-related molecules
12/26/2000US6165762 Amino acid sequence of enzyme; drug screening of bactericides and bacteriostats; vaccines; diagnosis of infections
12/26/2000US6165761 Carbohydrate oxidase and use thereof in baking
12/26/2000US6165759 Amino acid sequence; diagnosis, prophylaxis and therapy of infections; vaccines; bacteriostats; bactericides; screening of enzyme inhibitors and activators
12/26/2000US6165755 Chicken neuropeptide gene useful for improved poultry production
12/26/2000US6165753 Cyclin E genes and proteins
12/26/2000US6165752 Expression system which produces polypeptide of defined amino acid sequence when present in a cell; diagnosis and therapy for creutzfeldt-jakob disease and nervous system disorders; anticarcinogenic agents
12/26/2000US6165751 HLDAT86 polynucleotides
12/26/2000US6165750 Streptavidin tetramers have at least one monomer containing an amino acid modification that produces a reduced binding affinity for biotin, a modified off-rate, a modified on-rate, or an altered binding enthalpy; bioseparations, drug delivery
12/26/2000US6165748 Useful in the modulation of cellular formation, growth, differentiation, proliferation and/or maintenance of a variety of adult and embryonic tissues and organs
12/26/2000US6165747 Comprise morphogenic signals produced by tissue patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates
12/26/2000US6165746 Preventing endogenous aminopeptidase mediated n-terminal amino acid cleavage during expression of foreign genes in bacteria
12/26/2000US6165745 Recombinant production of immunoglobulin-like domains in prokaryotic cells
12/26/2000US6165744 Isolation and characterization of cDNAs coding for the α, β, and γ subunits of the high-affinity receptor for immunoglobulin E
12/26/2000US6165737 Screening modulators of human dff40 activity by contacting cell expressing recombinant, human dff40/dff45 complex with candidate; activating factor; and comparing apoptosis with or without candidate
12/26/2000US6165736 Developing diagnostic procedure for detecting stage of infection; producing antibody profile, generating serum corresponding to antibody profile, cloning bacteria using nucleic acid fragments, culturing, screening proteins
12/26/2000US6165733 γ II adaptin
12/26/2000US6165732 Drug screening by using lipid bilayer that has potassium- or chloride-selective channel formed from polpeptide of bcl-2 family, contacting compound with bilayer, and determining ion-selectivity of channel; indicates agonist or antagonist
12/26/2000US6165730 Amino acid sequences of epitopes; for immunoassay diagnosis and immunogens for vaccines
12/26/2000US6165722 Representations of bimolecular interactions
12/26/2000US6165720 Conjugating nucleic acid with a peptide nucleic acid in a sequence-specific manner prior to transfection, transfecting cell with conjugate, and monitoring intracellular location
12/26/2000US6165719 hKCa3/KCNN3 small conductance calcium activated potassium channel: a diagnostic marker and therapeutic target
12/26/2000US6165716 Diagnosis of migraine, bipolar disorder, unipolar depression, or susceptibility in human by sampling nucleic acids and analyzing number of copies of variable number tandem repeat region in the second intron of serotonin transporter gene
12/26/2000US6165713 Composition and methods relating to DNA mismatch repair genes
12/26/2000US6165712 Contacting a cell with an exogenous molecule effective to modulate gene expression and affect level of protein thus pathological effect; molecule binds to regulatory sequence, rna, or transcription regulating protein; viricides
12/26/2000US6165508 Controlled release of metal cation-stabilized interferon
12/26/2000US6165489 Multifunctionally activated synthetic hydrophilic polymer at least two functional groups capable of reacting with primary amino groups to form a crosslinked matrix between the crosslinked collagen and the noncrosslinked collagen
12/26/2000US6165478 DNA encoding Chlamydia pneumoniae antigenic polypeptide
12/26/2000US6165477 Mature recombinantly produced protein from eucaryotic cells which is protective against dengue infection, which raises antibodies useful in passive immunization, and which is useful in diagnosis of infection by the virus.
12/26/2000US6165476 Fusion proteins with an immunoglobulin hinge region linker
12/26/2000US6165472 Folyl-polyglutamate synthetase (fpgs) of s. pnuemoniae is necessary for a fully functional folate synthesis pathway. having a present benefit of being useful to screen compounds for antibiotic activity.
12/26/2000US6165471 Homogeneous human papillomavirus capsomere containing compositions, methods for manufacture, and use thereof as diagnostic, prophylactic or therapeutic agents
12/26/2000US6165470 Hybrid macromolecules composed of albumin derivatives coupled to derivatives of the cd4 receptor having a normal or a higher affinity for the hiv-1 virus.
12/26/2000US6165466 Antagonists of interleukin-15
12/26/2000US6165465 Immunologic enhancement of the somatogenic effect of somatotropin with an antibody
12/26/2000US6165464 Monoclonal antibodies directed to the HER2 receptor
12/26/2000US6165462 Sugar kinase
12/26/2000US6165460 Generation of immune responses to prostate-specific antigen (PSA)
12/26/2000US6165459 Methods for suppressing myeloid cells with chemokines
12/26/2000CA2046646C Plants transformed to produce bacillus thuringiensis insecticidal toxins
12/21/2000WO2000077486A2 Compositions and methods for detecting treponema pallidum
12/21/2000WO2000077281A1 Encapsulation of crystals via multilayer coatings
12/21/2000WO2000077262A1 Synthetic ligation reassembly in directed evolution
12/21/2000WO2000077256A1 48 human secreted proteins
12/21/2000WO2000077255A1 49 human secreted proteins
12/21/2000WO2000077254A1 Detection of streptococcus pneumoniae and immunization against streptococcus pneumoniae infection
12/21/2000WO2000077252A1 Diagnosis, prognosis and treatment of cancer related to the barx2 gene
12/21/2000WO2000077239A2 Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses
12/21/2000WO2000077238A1 Heterodimeric opioid g-protein coupled receptors
12/21/2000WO2000077237A1 49 human secreted proteins
12/21/2000WO2000077233A2 Complement-resistant non-mammalian dna viruses and uses thereof
12/21/2000WO2000077229A2 R1 protein from wheat and the use thereof for the production of modified strach
12/21/2000WO2000077227A1 Fibrin sealant as a transfection/transformation vehicle for gene therapy
12/21/2000WO2000077219A1 Method for determining hiv-1 subtype
12/21/2000WO2000077218A1 Vaccine for newcastle disease virus
12/21/2000WO2000077217A1 Nodavirus-based dna expression vector and uses thereof
12/21/2000WO2000077216A2 Porcine circovirus vaccine in recombinant poxvirus
12/21/2000WO2000077215A1 Cdc68p CHROMATIN REMODELING FACTOR
12/21/2000WO2000077214A2 Characterization of the yeast transcriptome
12/21/2000WO2000077213A2 Avirulent brucella and uses thereof
12/21/2000WO2000077212A1 Bacteriocin, preparation and use thereof
12/21/2000WO2000077211A1 Pyrexia-associated genes and pyrexia-associated proteins of plant
12/21/2000WO2000077210A1 Equine granulocyte-macrophage colony-stimulating factor (gm-csf)
12/21/2000WO2000077209A1 Helical cytokine zalpha33
12/21/2000WO2000077208A2 Gustatory receptors in drosophila
12/21/2000WO2000077207A2 Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto
12/21/2000WO2000077206A2 The myostatin gene promoter and inhibition of activation thereof
12/21/2000WO2000077205A1 HUMAN NUCLEAR FACTORS ASSOCIATED WITH dsRNA (NFAR)