| Patents for C07J 69 - Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by contraction of only one ring by one atom and expansion of only one ring by one atom (107) | |
|---|---|
| 12/2014 | |
| 12/10/2014 | CN102516350B 一种具有抗肿瘤活性的甘草次酸修饰物及其制备方法 Glycyrrhetinic acid modifications and preparation method with anti-tumor activity |
| 11/2014 | |
| 11/25/2014 | US8895576 Methods of use of cyclopamine analogs |
| 07/2014 | |
| 07/22/2014 | US8785635 Cyclopamine analogs |
| 04/2014 | |
| 04/17/2014 | WO2014059314A1 Treating brain cancer using agelastatin a (aa) and analogues thereof |
| 01/2014 | |
| 01/22/2014 | CN103524594A Method for separating cyclopamine analogs from Veratrum plants by high-speed counter-current chromatography |
| 07/2013 | |
| 07/16/2013 | US8486400 Methods of inhibiting unwanted cell proliferation using an antibody that binds to sonic hedgehog and inhibits hedgehog signaling |
| 03/2013 | |
| 03/13/2013 | CN101565446B Veratramine degradation product veratrum fluorene aldehyde and the derivatives thereof, as well as the preparation and application thereof |
| 02/2013 | |
| 02/05/2013 | CA2727986C Methods for obtaining cyclopamine |
| 01/2013 | |
| 01/22/2013 | US8357368 Methods of treating pancreatic or liver cancer using hedgehog antagonists |
| 06/2012 | |
| 06/27/2012 | CN102516350A Glycyrrhetinic acid modifier with antitumor activity and preparation method thereof |
| 05/2012 | |
| 05/31/2012 | US20120135066 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 05/30/2012 | CN101565445B Method for preparing high-purity veratramine and jervine |
| 04/2012 | |
| 04/25/2012 | EP2443926A2 Cyclopamine analogs |
| 04/24/2012 | US8163719 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 01/2012 | |
| 01/03/2012 | CA2452151C Use of cyclopamine, an inducer of the differentiation and apoptosis of the basal cell carcinoma (bcc) cells, in the treatment of bcc's and other tumors that use the hedgehog/smoothened pathway for proliferation of apoptosis |
| 11/2011 | |
| 11/16/2011 | CN102241727A Cyclopamine analogues and methods of use thereof |
| 10/2011 | |
| 10/27/2011 | US20110263519 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 09/2011 | |
| 09/28/2011 | EP2368551A2 Methods of use for cyclopamine analogs |
| 09/06/2011 | CA2502293C Ship 1 modulators |
| 08/2011 | |
| 08/16/2011 | US7998946 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 03/2011 | |
| 03/31/2011 | US20110076286 Methods of inhibiting unwanted cell proliferation using hedgehog antagonists |
| 01/2011 | |
| 01/13/2011 | US20110008333 Methods of inhibiting unwanted cell proliferation using hedgehog antagonists |
| 11/2010 | |
| 11/09/2010 | CA2326654C Use of steroidal alkaloid derivatives as inhibitors of hedgehog signaling pathways |
| 09/2010 | |
| 09/08/2010 | EP2224807A1 Methods for stereoselective reduction |
| 08/2010 | |
| 08/11/2010 | EP2216022A1 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 06/2010 | |
| 06/16/2010 | CN101735302A Preparation methods of 12 beta-hydroxyl veratroylzygadenine, veratrosine and veratramine, and applications to treating mental diseases |
| 06/16/2010 | CN101157716B Dicarbon drop freedelane triterpenoid and preparation method and uses thereof |
| 05/2010 | |
| 05/05/2010 | CN1525859B Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 05/04/2010 | US7708998 Methods of inhibiting unwanted cell proliferation using hedgehog antagonists |
| 02/2010 | |
| 02/02/2010 | US7655653 Tetrahydrobenzfluorene derivatives |
| 01/2010 | |
| 01/26/2010 | CA2505575C 17alpha-hydroxy-14beta-steroids with hormonal effect |
| 01/07/2010 | WO2010000070A1 Methods for obtaining cyclopamine |
| 01/07/2010 | CA2727986A1 Methods for obtaining cyclopamine |
| 01/04/2010 | CA2636807A1 Methods for obtaining cyclopamine |
| 10/2009 | |
| 10/28/2009 | CN101565446A Veratramine degradation product veratrum fluorene aldehyde and the derivatives thereof, as well as the preparation and application thereof |
| 10/28/2009 | CN101565445A Method for preparing high-purity veratramine and jervine |
| 09/2009 | |
| 09/09/2009 | EP2096917A2 Cyclopamine analogs |
| 09/02/2009 | CN100535000C Method of preparing cyclopamine from jervine |
| 08/2009 | |
| 08/12/2009 | CN100526329C Production of high-purity peiminine and fritimine |
| 04/2009 | |
| 04/14/2009 | CA2386190C Regulators of the hedgehog pathway, compositions and uses related thereto |
| 02/2009 | |
| 02/11/2009 | CN101362791A Steroidal alkaloid veratramine, preparation method thereof and antihypertensive application |
| 01/2009 | |
| 01/13/2009 | US7476661 for treating basal cell carcinomas, medulloblastomas, and tumors |
| 10/2008 | |
| 10/16/2008 | US20080255059 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 07/2008 | |
| 07/29/2008 | US7405207 Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof |
| 04/2008 | |
| 04/09/2008 | CN101157716A Dicarbon drop freedelane triterpenoid and preparation method and uses thereof |
| 03/2008 | |
| 03/06/2008 | US20080058361 Tetrahydrobenzfluorene derivatives |
| 01/2008 | |
| 01/02/2008 | EP1458743B1 Tetrahydrobenzfluorene derivatives |
| 12/2007 | |
| 12/04/2007 | US7304155 Nonsteroid; enantiomers are selective antagonists of the estrogen beta receptor relative to the alpha receptor; tissue selectivity; fewer estrogen-related side effects; menopause, osteoporosis, hormone replacent therapy, contraceptive, endometriosis; 10-aminoalkyloxyphenyl benzo[b]fluorene 2,8-diols |
| 08/2007 | |
| 08/15/2007 | CN101016329A Method of preparing cyclopamine from jervine |
| 07/2007 | |
| 07/04/2007 | CN1993343A Tetracyclic compounds as estrogen ligands |
| 06/2007 | |
| 06/20/2007 | CN1982328A Production of high-purity peiminine and fritimine |
| 03/2007 | |
| 03/14/2007 | EP1761513A1 Tetracyclic compounds as estrogen ligands |
| 12/2006 | |
| 12/06/2006 | EP1728797A2 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 06/2006 | |
| 06/15/2006 | US20060128639 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 05/2006 | |
| 05/31/2006 | EP1235851B1 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 01/2006 | |
| 01/26/2006 | US20060020020 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 01/19/2006 | CA2570518A1 Tetracyclic compounds as estrogen ligands |
| 12/2005 | |
| 12/07/2005 | CN1230169C Use of cyclopamine in the treatment of psoriasis |
| 09/2005 | |
| 09/28/2005 | EP1401438B1 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 08/2005 | |
| 08/10/2005 | EP1561464A2 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 06/2005 | |
| 06/02/2005 | US20050119264 Tetrahydrobenzfluorene derivatives |
| 09/2004 | |
| 09/22/2004 | EP1458743A1 Tetrahydrobenzfluorene derivatives |
| 09/01/2004 | CN1525859A Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 08/2004 | |
| 08/18/2004 | CN1522146A Use of cyclopamine in the treatment of psoriasis |
| 07/2004 | |
| 07/01/2004 | US20040127474 Contacting the cell with a ptc agonist in a sufficient amount to inhibit the altered growth state, wherein the ptc agonist is a organic molecule having a molecular weight less than about 750 amu for inhibiting an altered growth state of a cell |
| 06/2004 | |
| 06/10/2004 | US20040110663 Hedgehog antagonists, methods and uses related thereto |
| 04/2004 | |
| 04/01/2004 | US20040060568 Hedgehog antagonists, methods and uses related thereto |
| 03/2004 | |
| 03/31/2004 | EP1401438A1 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 03/25/2004 | WO2003040163B1 Immunomodulating saponins, a method for their preparation and their use for vaccines |
| 02/2004 | |
| 02/11/2004 | EP1387674A2 Hedgehog antagonists, methods and uses related thereto |
| 02/03/2004 | US6686388 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 12/2003 | |
| 12/04/2003 | WO2002030462A3 Hedgehog antagonists, methods and uses related thereto |
| 11/2003 | |
| 11/27/2003 | WO2003040163A3 Immunomodulating saponins, a method for their preparation and their use for vaccines |
| 07/2003 | |
| 07/03/2003 | WO2003053994A1 Tetrahydrobenzfluorene derivatives |
| 06/2003 | |
| 06/12/2003 | WO2002078703A8 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 05/2003 | |
| 05/15/2003 | WO2003040163A2 Immunomodulating saponins, a method for their preparation and their use for vaccines |
| 05/15/2003 | WO2002030462A9 Hedgehog antagonists, methods and uses related thereto |
| 11/2002 | |
| 11/07/2002 | US20020165221 Cellular antigrowth agents |
| 10/2002 | |
| 10/10/2002 | WO2002078704A1 Use of cyclopamine in the treatment of psoriasis |
| 10/10/2002 | WO2002078703A1 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| 09/2002 | |
| 09/04/2002 | EP1235851A2 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 08/2002 | |
| 08/15/2002 | WO2001027135A9 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 05/2002 | |
| 05/10/2002 | WO2001027135A3 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 04/2002 | |
| 04/18/2002 | WO2002030462A2 Hedgehog antagonists, methods and uses related thereto |
| 04/18/2002 | CA2425356A1 Hedgehog antagonists, methods and uses related thereto |
| 12/2001 | |
| 12/05/2001 | CN1075802C Asiatic acid derivatives having modified A-ring |
| 10/2001 | |
| 10/25/2001 | US20010034337 Antiproliferative agents |
| 10/17/2001 | EP1143961A2 Regulators of the ptc or smoothened pathway, compositions and uses related thereto |
| 09/2001 | |
| 09/18/2001 | US6291516 Contacting the cell with a composition including at least one cyclic amp agonist. |
| 06/2001 | |
| 06/13/2001 | EP0944571B1 Asiatic acid derivatives having modified a-ring |
| 04/2001 | |
| 04/19/2001 | WO2001027135A2 Regulators of the hedgehog pathway, compositions and uses related thereto |
| 01/2001 | |
| 01/17/2001 | EP1067939A1 Use of steroidal alkaloid derivatives as inhibitors of hedgehog signaling pathways |
| 09/2000 | |
| 09/28/2000 | WO2000041545A3 Regulators of the pct or smoothened pathway, compositions and uses related thereto |
| 07/2000 | |
| 07/20/2000 | WO2000041545A2 Regulators of the pct or smoothened pathway, compositions and uses related thereto |
| 07/20/2000 | CA2370042A1 Regulators of the pct or smoothened pathway, compositions and uses related thereto |
| 06/2000 | |
| 06/06/2000 | US6071898 Asiatic acid derivatives having modified A-ring |
| 12/1999 | |
| 12/15/1999 | CN1238755A Asiatic acid derivatives having modified A-ring |
| 10/1999 | |
| 10/21/1999 | WO1999052534A1 Use of steroidal alkaloid derivatives as inhibitors of hedgehog signaling pathways |
| 09/1999 | |
| 09/29/1999 | EP0944571A1 Asiatic acid derivatives having modified a-ring |
| 10/1998 | |
| 10/13/1998 | US5821253 Tetrahydrobenzo a!fluorene compounds and methods of use |
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