Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
05/1996
05/07/1996US5514785 Polymer coated bead for covalent immobilization of oligonucleotides; dipsticks
05/07/1996US5514585 Yeast processing system
05/07/1996US5514577 Oligonucleotide therapies for modulating the effects of herpes viruses
05/07/1996US5514569 Reducing inhibition of a nucleoside 5'-monophosphate on phosphodiesterase i by incubating the enzyme in the presence of a nucleoside 5'-monophosphate degrading enzyme
05/07/1996US5514568 Mutagenesis of circular or double-stranded dna
05/07/1996US5514546 Stem-loop oligonucleotides containing parallel and antiparallel binding domains
05/05/1996CA2162075A1 Modified oligonucleotides, their preparation and their use
05/02/1996WO1996012809A2 Nucleotide sequences of hiv-1 type (or subtype) o retrovirus antigens
05/02/1996WO1996012808A1 Nucleic acid preparation for immunization and method for immunization using the same
05/02/1996WO1996012497A1 Use of 2'-substituted oligonucleotides to down-regulating gene expression
05/02/1996WO1995029930A3 Improved method for oligonucleotide analog synthesis
05/02/1996CA2652992A1 Nucleotide sequences of hiv-1 type (or subtype) o retrovirus antigens
05/01/1996EP0709468A1 A process for making the product of a nucleic acid amplification reaction incapable of being a target for further amplification, a diagnostic assay employing said process, a kit and a container suitable for carrying out said process or assay
05/01/1996EP0709466A2 Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences
05/01/1996EP0709461A1 Recombinant thermostable enzyme which forms non-reducing saccharide from reducing amylaceous saccharide
05/01/1996EP0708832A1 Helicobacter pylori haemagglutinin/protease protein, nucleic acid encoding therefor and antibodies specific thereto
05/01/1996EP0708829A1 A pharmaceutical composition comprising antisense-nucleic acid for prevention and/or treatment of neuronal injury, degeneration and cell death and for the treatment of neoplasms
05/01/1996EP0708767A1 Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives
05/01/1996EP0708592A1 Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence
05/01/1996CN1121721A Oligonucleotido alky phosphate and alky substituted phosphate
04/1996
04/30/1996US5512668 Solid phase oligonucleotide synthesis using phospholane intermediates
04/30/1996US5512667 Trifunctional intermediates for preparing 3'-tailed oligonucleotides
04/30/1996US5512466 Expression of a 1-aminocyclopropane-1-carboxylic acid metabolizing enzyme to inhibit production of ethylene
04/30/1996US5512462 For amplification of nucleic acid sequences longer than ten kilobases
04/30/1996US5512457 Cytokine designated elk ligand
04/30/1996US5512438 Inhibiting RNA expression by forming a pseudo-half-knot RNA at the target's
04/30/1996US5512433 Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes
04/25/1996WO1996012039A1 Massively parallel sequencing of sorted polynucleotides
04/25/1996WO1996012017A1 Gene participating in apoptosis
04/25/1996WO1996012014A1 Molecular tagging system
04/25/1996WO1996011947A1 Materials for the production of nanometer structures and use thereof
04/25/1996WO1996011938A1 Oligonucleotide and carcinostatic agent containing the same as active ingredient
04/25/1996WO1996011937A1 Porphyrin labeling of polynucleotides
04/25/1996WO1995031541A3 Methods and compositions for treatment of restenosis and cancer using ribozymes
04/25/1996CA2441634A1 Molecular tagging system
04/25/1996CA2202628A1 Apoptosis-associated gene
04/25/1996CA2202480A1 Porphyrin labeling of polynucleotides
04/25/1996CA2202474A1 Materials for the production of nanometer structures and use thereof
04/24/1996EP0708180A2 Improved, inductionless process for the genetical preparation of glutarylamidase
04/24/1996EP0708178A1 Survival motor neuron (SMN) gene: a gene for spinal muscular atrophy
04/24/1996EP0707659A1 Salmonella identification by the polymerase chain reaction
04/24/1996EP0707653A1 Method for specific silencing of genes by dna methylation
04/24/1996EP0707649A1 Cisplatin resistance gene and uses therefor
04/24/1996EP0707648A1 Platelet glycoprotein v gene and uses
04/24/1996EP0707647A1 Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis
04/24/1996EP0707638A1 Regulatable nucleic acid therapeutic and methods of use thereof
04/24/1996EP0707592A1 Process for solid support nucleic acid synthesis and compounds useful as solid supports in said process
04/24/1996EP0707591A1 Methylphosphonic acid ester, process for preparing the same and its use
04/24/1996EP0707590A1 Dideoxyfructonucleotides and deoxyfructonucleotides as dna polymerase substrates
04/24/1996EP0707496A1 METHODS AND COMPOSITIONS FOR DETECTING AND TREATING MYCOBACTERIAL INFECTIONS USING AN inhA GENE
04/24/1996EP0648221A4 Trityl monitor for automated polynucleotide synthesis.
04/24/1996EP0625194B1 Enhancement of ribozyme catalytic activity by a neighboring facilitator oligonucleotide
04/24/1996EP0592434A4 Improved process for the synthesis of oligomers
04/24/1996EP0490951B1 Fragments of nucleic acids derived from an appropriate mycobacteria genome, their applications in the diagnosis of mycobateria infections and plasmides containing said fragments
04/24/1996CN1121355A Variants of bile salt-stimulated lipase, DNA molecules encoding them, and transgenic non-human mammals
04/24/1996CN1121313A Compositions and methods of application of reactive antiviral polymers
04/23/1996US5510476 Carbocation scavenging during oligonucleotide synthesis
04/23/1996US5510475 Attachment of reporters by way of phosphonamidate linkers, having protected hydroxyl or amino functionality
04/23/1996US5510270 Generating pattern of light and dark areas by selectively irradiating surface areas; deprotecting; contacting with receptor to identify oligonucleotide showing complementarity to receptor
04/23/1996US5510249 Fusion of signal peptide, a leader peptide, a heterogenous protein or polypeptide; genetic engineering
04/23/1996US5510240 Method of screening a peptide library
04/23/1996US5510239 One of the intersugar linkages between nuclotide units of the oligonuclotide is phosphorothioate linkage
04/23/1996US5510084 Process for immobilizing a nucleic acid fragment by passive attachment to a solid substrate, the solid substrate thus obtained, and its use
04/20/1996CA2160861A1 Induction-free process for the recombinant preparation of glutarylamidase
04/19/1996CA2138425A1 Neuronal apoptosis inhibitor protein, gene sequence and mutations causative of spinal muscular atrophy
04/18/1996WO1996011269A2 Tie-2 ligands, methods of making and uses thereof
04/18/1996WO1996011205A1 Peptide nucleic acid conjugates
04/18/1996WO1996011010A1 Bridged and unbridged quadruplex/duplex oligonucleotides
04/17/1996EP0707077A2 Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
04/17/1996EP0707071A1 Recombinant vectors derived from adenovirus for use in gene therapy
04/17/1996EP0707067A2 A novel gene coding thrombin-like protease
04/17/1996EP0707066A2 Method for producing the SspI restriction endonuclease and methylase
04/17/1996EP0706573A1 Protein tyrosine kinase and ligands thereof
04/17/1996EP0706563A1 A truncated keratinocyte growth factor (kgf) having increased biological activity
04/17/1996EP0706531A1 Synthesis of branched nucleic acids
04/17/1996EP0686043A4 Compositions and methods of application of reactive antiviral polymers
04/16/1996US5508387 Selectin binding glycopeptides
04/16/1996US5508289 Bis-acridone chemotherapeutic derivatives
04/16/1996US5508270 Nucleoside phosphinate compounds and compositions
04/16/1996US5508176 Allows preparation of mutarotase in genetic engineering process in high yields
04/16/1996US5508169 Treating dna with restriction endonuclease yields synthetic nucleic acids which can be selectively joined to end groups of unknown dna fragments for detection and analysis
04/16/1996US5508168 Methods and reagents for the detection of herpes simplex virus, treponema pallidum, and haemophilus ducreyi
04/11/1996WO1996010647A1 Probe for diagnosing infectious diseases
04/11/1996WO1996010640A1 Cloned dna polymerases from thermotoga neapolitana and mutants thereof
04/11/1996WO1996010576A1 HIGH-AFFINITY OLIGONUCLEOTIDE LIGANDS TO IMMUNOGLOBULIN E (IgE)
04/11/1996WO1996006935A3 Arabinoxylan degrading enzymes
04/11/1996EP0733125A4 A representational approach to dna analysis
04/11/1996CA2201506A1 Novel protein marker and dna encoding same
04/11/1996CA2174944A1 Cloned dna polymerases from thermotoga neapolitana and mutants thereof
04/10/1996EP0705905A2 Method for the sensitive detection of nucleic acids
04/10/1996EP0705435A1 A novel family of pollen proteinases, methods of use thereof and compositions derived therefrom
04/10/1996EP0705341A1 Hybrid receptor molecules
04/10/1996EP0705339A1 Human cell adhesion protein aamp-1 and uses thereof
04/10/1996EP0705336A1 Test and model for polycystic ovary syndrome and male pattern baldness
04/10/1996EP0705335A1 Antisense oligonucleotides and therapeutic use thereof in human immunodeficiency virus infection
04/10/1996EP0705271A1 Hybridization and sequencing of nucleic acids
04/10/1996EP0705270A1 Chemically modified oligonucleotide for site-directed mutagenesis
04/10/1996EP0649429A4 Heteroatomic oligonucleoside linkages.
04/10/1996EP0448697B1 Vitamin a analogues and their applications, in particular as cytotrophic and cytoprotective molecules, and pharmaceutical compositions containing same
04/10/1996CN1120352A Stable bactericidal/permeability-increasing protein products and pharmaceutical compositions containing the same