Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
01/2003
01/08/2003EP1272506A1 Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis
01/08/2003EP1272501A1 Process for the preparation of phosphorothioate triesters
01/08/2003EP0728194B1 In situ modification and manipulation of stem cells of the central nervous system
01/08/2003CN1389569A Prepn. of double-stranded nucleic acid on surface of solid support
01/07/2003US6505126 Identifying nucleic acids and polypeptides
01/07/2003US6504024 Useful as substrates for polymerase enzymes; used in preparing fluorescently-labeled nucleotides useful as substrates for thermostable polymerases
01/07/2003US6504019 Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof
01/07/2003US6503759 Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the
01/07/2003US6503728 A nucleic acid comprising a nucleic acid sequence encoding pantropic hNT3 or hNGF having an alanine residue substituted at a position corresponding to D15 in hNT3 or D16 in hNGF, wherein the alanine substitution imparts trkB-binding such
01/07/2003US6503720 Method for quantification of an analyte
01/07/2003US6503533 Antisense ogligonucleotides against Hepatitis B viral replication
01/07/2003US6503508 Detergents
01/07/2003CA2252813C 3- and 3,8-substituted 1,10-phenanthrolines and their use in electron and energy transfer processes
01/07/2003CA2089666C Oligonucleotides for modulating the effects of cytomegalovirus infections
01/03/2003WO2003000941A2 Polypeptides having cellobiohydrolase i activity and polynucleotides encoding same
01/03/2003WO2003000935A1 Methods and oligonucleotides for the detection of salmonella sp.,e.coli o157:h7,and listeria monocytogenes
01/03/2003WO2003000933A1 Dual resonance energy transfer nucleic acid probes
01/03/2003WO2003000932A1 Method for identifying genes that are upstream regulators of other genes of interest
01/03/2003WO2003000922A2 Chimeric immunomodulatory compounds and methods of using the same
01/03/2003WO2003000903A2 Regulation of human nek-like serine/threonine protein kinase
01/03/2003WO2003000887A1 Polynucleotide probe and primer originating in hepatitis e virus of japanese, chips having the same, kits having the same and method of detecting hepatitis e virus using the same
01/03/2003WO2003000844A2 Protein modification and maintenance molecules
01/03/2003WO2003000842A2 Novel proteins and nucleic acids encoding same
01/03/2003WO2003000841A2 Dye-labeled ribonucleotide triphosphates
01/03/2003WO2002051856A3 Method for immobilising probes, in particular for producing biochips
01/03/2003WO2002026757A3 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
01/03/2003WO2002002627A3 Interferon-like protein zcyto21
01/03/2003CA2677781A1 Nitrilases
01/03/2003CA2451974A1 Chimeric immunomodulatory compounds and methods of using the same
01/03/2003CA2451498A1 Methods and oligonucleotides for the detection of salmonella sp., e. coli o157:h7, and listeria monocytogenes
01/03/2003CA2450921A1 Protein modification and maintenance molecules
01/02/2003US20030004325 Stability; nuclease resistance
01/02/2003US20030004122 Anticancer agents
01/02/2003US20030004120 Apoptosis; antitumor, anticancer agents
01/02/2003US20030004102 Genetic engineering; immunosuppressants, anticancer agents
01/02/2003US20030003598 Method, system and computer program product for measuring unit activity of an enzyme
01/02/2003US20030003556 Human collagenase inhibitor, recombinant vector system for using same and recombinant DNA method for the manufacture of same
01/02/2003US20030003547 Controlling homologous recombination; obtain nucleotide sequence, incubate with oligonucleotide, monitor adjustment in gene and phenotypic expression
01/02/2003US20030003546 Treating degenerative cartilaginous disorders and other inflammatory diseases
01/02/2003US20030003536 Vanilloid receptor
01/02/2003US20030003531 Secreted and transmembrane polypeptides and nucleic acids encoding the same
01/02/2003US20030003530 Nucleotide sequences coding protein for use in diagnosis and treatment of skin and cancer disorders
01/02/2003US20030003499 Generation of solid support for biopolymer analysis; form probe arrays on substrate, separate substrate, join substrate to package, recover package
01/02/2003US20030003490 Mapping preferential nucleic acid position in biopolymer; obtain nucleotide sequence sample, incubate with probe, amplify, determine position of preferential nucleotide sequences
01/02/2003US20030003483 Amplifiable probe
01/02/2003US20030003475 Arrays for detecting nucleic acids
01/02/2003US20030003473 Electrodes linked via conductive oligomers to nucleic acids
01/02/2003US20030003472 Detection of genetic aberration in sample; obtain nucleotide sequences, incubate with oligonucleotides, detect aberration in hybridization, presence of aberration indicates variablity in nucleotide sequences
01/02/2003US20030003468 Markers for disease susceptibility and targets for therapy
01/02/2003US20030003461 Truncation selex method
01/02/2003US20030003460 Microparticles for use as luminesencent tool in bioassays
01/02/2003US20030003143 Lipidic microparticles linked to multiple proteins
01/02/2003EP1271146A1 Method and composition of cellular reprogramming
01/02/2003EP1268793A2 Fibroblast growth factor receptor-like molecules and uses thereof
01/02/2003EP1268706A1 Trityl-type compounds and their use
01/02/2003EP1268527A2 Nucleic acids, proteins, and antibodies
01/02/2003EP1268509A1 Mammalian sphingosine kinase type 2 isoforms, cloning, expression and methods of use thereof
01/02/2003EP1268508A1 Quality control reagents for nucleic acid microarrays
01/02/2003EP1268507A1 Antisense modulation of e2f transcription factor 1 expression
01/02/2003EP1268505A2 Solid phase synthesis method and reagent
01/02/2003EP1268492A1 Reactive monomers for the oligonucleotide and polynucleotide synthesis, modified oligonucleotides and polynucleotides, and a method for producing the same
01/02/2003EP1268052A2 High throughput screening array containing porous material
01/02/2003EP1023463A4 Modifying double stranded dna to enhance separations by matched ion polynucleotide chromatography
01/02/2003EP1002137A4 Denaturing multi ion polynucleotide chromatography for detecting mutations
01/02/2003EP0745131B1 Targeting gene therapy
01/01/2003CN1388252A Gene cluster for using hydrophanous streptomycete 17997 in synthesizing geldanamycin biologically
01/01/2003CN1388132A Cell death inducing protein and its coding sequence and use
01/01/2003CN1388130A Human hematopoietic cell relating gene-1
12/2002
12/31/2002US6500945 Nucleotides having chiral phosphorus linkages
12/31/2002US6500944 Sulfurizing reagent: 3-aryl-1,2,4-dithiazoline-5-ones
12/31/2002US6500922 Native polypeptide factors that are capable of association with the intracellular domain of tnf-r2 and participate in the intracellular post-receptor signaling of tnf biological activities
12/31/2002US6500664 Growth differentiation factor-8 family nucleic acid sequences
12/31/2002US6500663 Unique associated Kaposi's sarcoma virus sequences and uses thereof
12/31/2002US6500662 Infectious cdna clones of positive polarity rna viruses and the construction of vaccines, in particular, swine vaccines, using such cdna clones
12/31/2002US6500659 A thermostable enzyme that catalyzes the removal of arginine, phenylalanine, or methionine from the n-terminal end of peptides
12/31/2002US6500650 Method for identifying polymorphisms
12/31/2002US6500647 Recombinant expression vector which is prepared by inserting a human parathyroid hormone gene containing a urokinase-specific cleavage site into an l-arabinose inducible vector containing a phosphoribulokinase gene fragment of
12/31/2002CA2244964C Detection of nucleic acids by fluorescence quenching
12/30/2002CA2841397A1 Novel compositions and processes for improved analyte detection using hybridization assays
12/30/2002CA2841389A1 Novel compositions and processes for improved analyte detection using hybridization assays
12/30/2002CA2714119A1 Novel compositions and processes for improved analyte detection using hybridization assays
12/27/2002WO2002103052A1 Amplifiable probe
12/27/2002WO2002103045A2 Improvements in and relating to the provision of dna investigating tools
12/27/2002WO2002103031A2 Methods for detecting and treating the early onset of aging-related conditions
12/27/2002WO2002103008A2 Templated molecules and methods for using such molecules
12/27/2002WO2002102836A2 Moraxella (branhamella) catarrhalis antigens
12/27/2002WO2002102820A1 Nucleoside derivatives for library preparation
12/27/2002WO2002102815A2 Methods for preparing oligonucleotides having chiral phosphorothioate linkages
12/27/2002WO2002102318A2 Eglin c based drugs for treatment of disease
12/27/2002WO2002102310A2 Proteins associated with cell growth, differentiation, and death
12/27/2002WO2002072864A3 Reagents for oligonucleotide cleavage and deprotection
12/27/2002WO2002062973A3 Lipase variants
12/27/2002WO2002060454A3 Use of dinucleoside polyphosphate to stimulate removal of fluid in retinal disorders
12/27/2002WO2002040515A3 Exoenzyme toxin of aeromonas salmonicida, and uses thereof
12/27/2002WO2002040514A3 Type iii secretion pathway in aeromonas salmonicida, and uses therefor
12/27/2002WO2002000877A3 Antisense oligonucleotides to inhibit angiogenesis and/or metastasis
12/27/2002WO2001056691A3 Method and device for the synthesis and the analysis of support-bound arrays of oligomers, especially of primer pairs for pcr, as well as oligomer-carrying supports
12/27/2002CA2455254A1 Moraxella (branhamella) catarrhalis antigens
12/27/2002CA2451524A1 Templated molecules and methods for using such molecules
12/27/2002CA2450809A1 Methods for detecting and treating the early onset of aging-related conditions