Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/2004
06/03/2004US20040106568 Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation
06/03/2004US20040106567 inhibiting expression of a gene in an extravascular mammalian cell by: a) injecting a naked polynucleotide into a blood vessel lumen; b) increasing permeability in the vessel; and, c) delivering the polynucleotide to an extravascular cell
06/03/2004US20040106555 Neurogenin3 and production of pancreatic islet cells
06/03/2004US20040106171 Peptides with anti-hypertensive properties
06/03/2004US20040106145 Method and apparatus for the automated generation of nucleic acid ligands
06/03/2004US20040106137 Comprises nucleotide sequences coding heat resistant single stranded DNA binding protein comprising polymerases activity for use as replication tool in genetic engineering
06/03/2004US20040106130 Bioarray chip reaction apparatus and its manufacture
06/03/2004US20040106121 Static micro-array of biological or chemical probes immobilised on a support by magnetic attraction
06/03/2004US20040106109 Restriction mediated selection polymerase chain reaction (REMS-PCR); DNA primers and probes for amplifying and determining ras mutationsin one or more nucleic acids including excess wild type
06/03/2004US20040105932 Substrate preparation process
06/03/2004US20040105855 Compries immunoglobulin which binds tumor necrosis factor receptor and functions as antitumor agent in the treatment of cancer
06/03/2004CA2506581A1 Novel 2',5'-oligoadenylic acid analogues
06/03/2004CA2506576A1 Amino-lna, thio-lna and alpha-l-oxy-ln
06/03/2004CA2505735A1 Methods for diagnosing the presence or stage of cancer
06/03/2004CA2505721A1 Rnai-based sensors, caged interfering rnas, and methods of use thereof
06/03/2004CA2505603A1 Caged sensors, regulators and compounds and uses thereof
06/03/2004CA2504267A1 Interferon-alpha polypeptides and conjugates
06/03/2004CA2489360A1 Methods and compositions for determining methylation profiles
06/03/2004CA2483870A1 Interacting site for gp41 on gp120 of hiv-1
06/02/2004EP1423697A2 Secreted proteins
06/02/2004EP1423535A2 Haplotype map of the human genome and uses therefor
06/02/2004EP1423510A2 Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
06/02/2004EP1423431A2 Antibodies to vla-1
06/02/2004EP1423426A1 Sut-2 and sut-3 genes, proteins and assays for inhibitors of lymphocyte adhesion
06/02/2004EP1423425A2 Receptor, the use thereof, and mouse antibodies
06/02/2004EP1423419A2 Hybrid and tandem expression of neisserial proteins
06/02/2004EP1423415A2 Intracellular signaling molecules
06/02/2004EP1423406A2 Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
06/02/2004EP1423404A2 RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA)
06/02/2004EP1423401A2 Lp354 mammalian secreted protein
06/02/2004EP0815210B1 An enzyme with aminopeptidase activity
06/02/2004CN1501940A Composition and method for inhibiting platelet aggregation
06/02/2004CN1500876A Full length polynucleotide order of coding fowl ó� type collagen and uses thereof
06/02/2004CN1500803A Bc-2 antisense thiophosphoric acid oligodeoxynucleotides anticancer drugs, preparing method and uses thereof
06/02/2004CN1500802A Phenol hydroxylase gene and uses thereof
06/02/2004CN1500801A Gene capable of improving the nitrogen fixing ability of combined azotobacter and uses thereof
06/02/2004CN1152043C Process for extracting nucleotide from waste monosodium glutamate
06/02/2004CN1151775C Method of treating dry eye disease with purinergic receptor agonists
06/01/2004US6743909 Being 20 to 80 nucleobases in length targeted to 1771 through 1790 of coding region; having at least one modified inter-nucleoside linkage, sugar moiety or nucleobase
06/01/2004US6743908 For use in cancer diagnosis and therapy
06/01/2004US6743906 For oncology, lung carcinomas; packaged in liposome or retrovirus
06/01/2004US6743905 Biopolymer for use in the detection of preerential sequences in sample
06/01/2004US6743903 Enzyme-linked immunoassay kits; microarrays
06/01/2004US6743902 For use in antisense therapy for enhancing nuclease resistance and cellular uptake
06/01/2004US6743896 Protien for use in the treatment of infection and tumors
06/01/2004US6743882 Functionalized silicon compound for use in the treatment of glass
06/01/2004US6743621 Human proteases and polynucleotides encoding the same
06/01/2004US6743589 Diagnosing depression in humans; obtain tissue sample, extract nucleotide sequence, determine genotype with respect to preferential receptor, presence of mutation in untranslated region of receptor gene indicates depression
06/01/2004US6743588 Compound for use in the detection of nucleic acids in sample
06/01/2004US6743578 Method for the detection of specific nucleic acid sequences by polymerase nucleotide incorporation
06/01/2004US6743428 Angiogenesis inhibitor
06/01/2004CA2170605C Mutants of the rb and p53 genes and uses thereof
05/2004
05/27/2004WO2004044245A1 Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation
05/27/2004WO2004044217A2 Dna sequences from tcd genomic region of photorhabdus luminescens
05/27/2004WO2004044178A2 Methods and compositions for diagnosing dysplasia
05/27/2004WO2004044177A2 Expression profiling based on histocultures
05/27/2004WO2004044164A2 Method for identifying risk of melanoma and treatments thereof
05/27/2004WO2004044163A2 Methods for identifying risk of melanoma and treatments thereof
05/27/2004WO2004044141A2 Conjugated oligomeric compounds and their use in gene modulation
05/27/2004WO2004044140A2 2’-substituted oligomeric compounds and compositions for use in gene modulations
05/27/2004WO2004044139A2 Modified oligonucleotides for use in rna interference
05/27/2004WO2004044138A2 Chimeric oligomeric compounds and their use in gene modulation
05/27/2004WO2004044137A2 Modified oligomeric compounds and compositions for use in gene modulation
05/27/2004WO2004044136A2 Compositions comprising alternating 2’-modified nucleosides for use in gene modulation
05/27/2004WO2004044135A2 Structural motifs and oligomeric compounds and their use in gene modulation
05/27/2004WO2004044134A2 Phosphorous-linked oligomeric compounds and their use in gene modulation
05/27/2004WO2004044133A2 Modified oligonucleotides for use in rna interference
05/27/2004WO2004044132A2 Modified oligonucleotides for use in rna interference
05/27/2004WO2004044131A2 Cross-linked oligomeric compounds and their use in gene modulation
05/27/2004WO2004043979A2 Sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
05/27/2004WO2004043978A2 2'-methoxy substituted oligomeric compounds and compositions for use in gene modulations
05/27/2004WO2004043977A2 2’-fluoro substituted oligomeric compounds and compositions for use in gene modulations
05/27/2004WO2004043976A2 Mkk7gamma1 nucleic acids and polypeptides
05/27/2004WO2004043407A2 Methods and products for treating staphylococcal infections
05/27/2004WO2004043344A2 Anti-cd33 antibodies and method for treatment of acute myeloid leukemia using the same
05/27/2004WO2004043332A2 Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
05/27/2004WO2004043232A2 Methods for identifying risk of melanoma and treatments thereof
05/27/2004WO2004043227A2 Polynucleotides for the amplification and detection of chlamydia trachomatis and neisseria gonorrhoeae
05/27/2004WO2004018626A3 Abasic site endonuclease assay
05/27/2004WO2004009762A3 Flea and tick octopamine receptor nucleic acid molecules, proteins and thereof
05/27/2004WO2003089455A3 Low-cost production of peptides
05/27/2004WO2003075655A3 Novel vip3 toxins and methods of use
05/27/2004WO2003045310A8 Digital assay
05/27/2004WO2002099141A9 Fluorescent quenching detection reagents and methods
05/27/2004US20040103455 Comprises nucleotide sequences coding insecticidal protein for generation and propagation of insect resistant plants; biological pest control
05/27/2004US20040102618 Human RNase H1 and oligonucleotide compositions thereof
05/27/2004US20040102413 Method and reagent for the inhibition of telomerase enzyme
05/27/2004US20040102406 Phosphorothioate oligonucleotides directed to a subunit of an integrin vitronectin receptor to inhibit angiogenesis and/or metastasis
05/27/2004US20040102395 Modulation of IAP-like expression
05/27/2004US20040102394 Using compositions comprising oligonucleotides targeted to nucleic acid encoding huntingtin interacting protein 2; for diagnosis and treatment of disease associated with expression of huntingtin interacting protein 2
05/27/2004US20040102393 Using compounds comprising oligonucleotides targeted to nucleic acid encoding heat shock protein 90-alpha for diagnosis and treatment of disease associated with expression of heat shock protein 90-alpha
05/27/2004US20040102392 Modulation of ADAM15 expression
05/27/2004US20040102372 Therapeutic antiangiogenic compositions and methods
05/27/2004US20040101947 A cationic or nonionic surfactant having a hydrophobic-lipophilic balance value from about 11 to 16 and a cell membrane altering compound, used for extracting a protein or peptide from target cell
05/27/2004US20040101927 Comprises nucleotide sequences coding polypeptides for diagnosis, prognosis, prevention and treatment of neurodegenerative and cancer disorders
05/27/2004US20040101894 Microarrays having multiple oligonucleotides in single array features
05/27/2004US20040101893 Abasic site endonuclease assay
05/27/2004US20040101892 Nucleic acid labeling compounds
05/27/2004US20040101890 Nucleic acid mediated electron transfer
05/27/2004US20040101872 Lipocalins