Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
01/2006
01/31/2006US6991902 Nucleobase heterocyclic combinatorialization
01/31/2006CA2346447C Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection
01/25/2006EP1618204A2 Process for preparing dideoxyinosine using adenosine deaminase enzyme
01/25/2006EP1495040A4 Method for synthesizing beta-l-fluoro-2',3'didehydcytidine (beta-l-fd4c)
01/25/2006CN1726223A Process for purifying oligonucleotide synthons
01/25/2006CN1724553A Synthesis method of 2-deoxy-2',2'-difluoro cytidine
01/25/2006CN1723903A Matrix metalloproteinase and tumor necrosis factor inhibitors
01/24/2006US6989376 Nervous system disorders; administering exogenous uridine compound
01/24/2006US6989147 Tumor necrosis factor receptor protein for use in the treatment of arthritis
01/19/2006WO2005108411A3 Substituted pixyl protecting groups for oligonucleotide synthesis
01/19/2006US20060014972 Method of fluorination
01/19/2006US20060014944 Processes for production of nucleosides
01/19/2006US20060014943 Process for the synthesis of pyrazolopyrimidines
01/19/2006CA2573532A1 Compositions and methods for detection of hepatitis a virus nucleic acid
01/18/2006EP1616034A2 Acyl- phosphate and phosphonate probes and methods of their synthesis and use in proteomic analysis
01/18/2006EP1404347B1 4'-substituded nucleosides for the treatment of diseases mediated by the hepatitis c virus
01/18/2006EP1097162B1 Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages
01/18/2006CN1723216A Process for producing phosphoroamidite
01/18/2006CN1723215A Anhydrous crystalline azido cytosine hemisulfate derivative
01/18/2006CN1723214A Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
01/17/2006US6987180 Nucleoside phosphate having 5-aminouracil group for incorporation into DNA via treatment with oxidizing agent or alkaline solution which cleaves position of unnatural nucleotide base; polymerase chain reactions
01/17/2006US6987177 Modified oligonucleotides, their preparation and their use
01/17/2006US6987091 Sir2 products and activities
01/12/2006US20060009636 Synthesis of protected 3'-amino nucleoside monomers
01/12/2006US20060009635 Method for purifying 5' -protected 2' -deoxypurine nucleosides
01/12/2006US20060009628 CONTAINING A 3-SUBSTITUTED PYRRAZOLO(,3,4-d) PYRIMIDINE
01/12/2006US20060009417 Contacting (4S,2R,3R,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol with a protected (2-hydroxy) cyclopentylamine compound having a protecting group on the 2-hydroxy moiety;contacting=with thionyl chloride in the presence of a second base;contacting with base, removing protecting group
01/12/2006US20060008461 Delivering into phagocytic cells; targeting specific organelles; inhibiting, attenuating, arresting, combating and overcoming microbial infection of phagocytic mammalian cells in vivo and in vitro
01/12/2006US20060008459 Combination therapy of respiratory diseases using antibodies
01/12/2006US20060008421 Pharmaceutical combination
01/12/2006US20060005742 Pearl essence-analogous pearlescent pigments prepared by enzymatic reaction
01/11/2006EP1341412B1 Indolocarbazole anticancer agents and methods of using them
01/11/2006EP1276748B1 13-substituted milbemycin derivatives, their preparation and their use against insects and other pests
01/11/2006EP1124839B1 Nucleosides with anti-hepatitis b virus activity
01/11/2006EP1001035B1 Novel antibiotics rk-1061 and process for preparing the same
01/11/2006EP0821692B1 Immunopotentiating inosine monophosphate 5'-nucleotidase resistant derivatives and uses thereof
01/11/2006CN1720333A Gas jet process and apparatus for high-speed amplification of DNA
01/11/2006CN1720332A Substrates for O6-alkylguanine-DNA alkyltransferase
01/11/2006CN1720256A Method of fluorination
01/10/2006US6984491 Detection of preferential nucleotide sequences in sample; obtain nucleotide sequence sample, incubate with oligonucleotide conjugated to nanoparticle, detect adjustment sequence activity, adjustment in activity indicates bound
01/10/2006US6984396 Conjugate having a cleavable linkage for use in a liposome
01/10/2006CA2163520C L-2',3'-dideoxy nucleoside analogs as anti-hepatitis b (hbv) and anti-hiv agents
01/05/2006US20060003963 Oxidizing and fluorinating the anhydroglucose to obtain 2-deoxy-2,2-difluoro-D-ribofuranose as intermediate; can be used in large-scale production
01/05/2006US20060003951 Anti-viral 7-deaza L-nucleosides
01/05/2006US20060003349 Tm leveling compositions
01/05/2006CA2567848A1 Methods and compositions for treating neuropathies
01/04/2006EP1612213A1 Process for producing 2 -deoxy-2 -fluorouridine
01/04/2006EP1610784A2 Forms of 5-azacytidine
01/04/2006EP1265621B1 Use of cdp-choline for the prophylactic treatment of cerebral ischemia
01/04/2006EP0668931B1 Nucleic acid ligands and methods for producing the same
01/04/2006CN1715918A Configurable dynamic three dimensional array
01/03/2006CA2136622C Phosphotriester-type biologically active compounds
01/03/2006CA2135853C Process for large-scale preparation of 2',3'-didehydro-2',3'-dideoxynucleosides
01/03/2006CA2135852C 5-methyluridine process for large-scale preparation of 2',3'-didehydro-3'-deoxythymidine (d4t)
12/2005
12/29/2005WO2005123755A2 Purine nucleotide derivatives
12/29/2005WO2005094322A3 Effective treatment of tumors and cancer with triciribine and related compounds
12/29/2005WO2005087788A3 Methods for preparation of nucleoside phosphonate esters
12/29/2005US20050288500 synthesized by reacting a 2-chloro-6-substituted purine with a protected and activated 2-deoxy-2-fluoro-D-arabinofiranose; and reacting with a base such as ammonia to provide 2-chloro-9-(2-deoxy-2-fluoro- beta -D-arabinofuranosyl)-9H-purin-6-amine
12/29/2005US20050288499 Modified guanosines having flavouring activity
12/29/2005US20050288240 Conversion by human liver microsomes to MPO3H2; hepatitis, cancer, liver fibrosis, malaria, other viral and parasitic infections, and metabolic diseases where the liver is responsible for the overproduction of the biochemical end product, diabetes; enhanced oral drug delivery
12/29/2005US20050288221 Glycopeptide antibiotics
12/29/2005DE60202483T2 Verfahren zur herstellung von l-ribavirin A process for the preparation of L-Ribavirin
12/29/2005CA2568907A1 8-carbyl substituted cyclic adenosine-3'-5'-monophosphorothiolate compounds as camp modulators
12/28/2005EP1608688A2 Branched water-soluble polymers and their conjugates
12/28/2005EP1608669A1 Silylated oligonucleotide compounds
12/28/2005EP1608634A2 Methods for isolating crystalline form i of 5-azacytidine
12/28/2005EP1497455A4 Detection of nucleic acid sequences by cleavage and separation of tag-containing structures
12/28/2005EP1427852A4 Single nucleotide amplification and detection by polymerase
12/28/2005EP1421213A4 Labeled nucleoside polyphosphates
12/28/2005EP0805683B1 5-fluoro-2',3'-unsaturated-pyrimidine nucleosides
12/28/2005CN1714099A Antiviral nucleoside derivatives
12/28/2005CN1714098A Crystalline and amorphous forms of beta-l-2'-deoxythymidine
12/28/2005CN1714097A Organic compounds of 2'-o-trisubstituted siloxy methyl ribonucleoside derivatives and their preparation
12/28/2005CN1714060A Method for deuteration or tritiation of heterocyclic ring
12/28/2005CN1712409A Nucleoside fluoride compound, its production and use
12/22/2005WO2005121361A2 Sequence-specific detection of methylation in biomolecules
12/22/2005WO2005121162A1 3-β-D-RIBOFURANOSYLTHIAZOLO[4,5-d]PYRIDIMINE NUCLEOSIDES AND USES THEREOF
12/22/2005WO2005097814A3 Composition and method for inhibiting platelet aggregation
12/22/2005WO2005096706A3 Antibody to 5'-deoxy-5'-methylthioadenosine and uses thereof
12/22/2005WO2005084367A3 Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry
12/22/2005US20050282769 Inhibitors of adenosine kinase for the treatment of optic nerve and retinal damage
12/22/2005US20050282768 Cardiovascular disease, a neurological disorder, an ischemic condition, a reperfusion injury, obesity, a wasting disease, or diabetes
12/22/2005DE29825173U1 Fludarabine phosphate purification by precipitation from aqueous acetone as stable metal salt, useful as cytotoxic drug
12/22/2005DE10120797B4 Verfahren zur Analyse von Nukleinsäureketten A process for the analysis of nucleic acid chains
12/21/2005EP1606233A2 Nucleotide lipid ester derivatives
12/21/2005EP1104436B1 Beta-l-2'-deoxy-nucleosides for the treatment of hepatitis b virus
12/21/2005CN1711278A Novel cytosine monophosphate medicine precursor
12/20/2005US6977246 Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
12/20/2005US6977178 System and method for transgenic and targeted mutagenesis screening
12/15/2005WO2005118608A2 2’-nitrobenzyl-modified ribonucleotides
12/15/2005WO2005117910A2 Purine derivatives as adenosine a1 receptor agonists and methods of use thereof
12/15/2005WO2005079155A3 Photoreactive compound specifically binding to calcium binding proteins
12/15/2005WO2004083258A3 Branched water-soluble polymers and their conjugates
12/15/2005US20050277616 Thymine nucleosides with anti-hepatitis B virus activity
12/15/2005US20050277614 Methods for modulating the axonal outgrowth of central nervous system neurons
12/15/2005CA2569491A1 2'-nitrobenzyl-modified ribonucleotides
12/15/2005CA2567289A1 Purine derivatives as adenosine a1 receptor agonists and methods of use thereof
12/14/2005EP1604995A1 Novel guanosine derivatives and use thereof
12/14/2005EP1604671A1 Muscle-building agent and preventive or remedy for muscle weakening
12/14/2005CN1706855A Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
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