| Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008) |
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| 09/29/2010 | CN101845071A Nucleoside derivative of 2' or 3' coupling amino acid, preparation method and application thereof |
| 09/29/2010 | CN101845070A Synthesis method of antineoplastic medicine capecitabine |
| 09/29/2010 | CN101492482B Synthesis process of the industrial production of gemcitabine hydrochloride |
| 09/28/2010 | US7803944 Viral polymerase inhibitors |
| 09/28/2010 | US7803943 Use of bridged nucleic acid fluorescent dyes, such as phenanthridinium dyes, cyanine dyes, or acridinium dyes each having an ammonium group and anion; bridging group can be -CH2-CONH-(CH2-CH2-O)x-(CH2)2-NHCO-CH2- ; low background fluorescence in the absence of nucleic acids; noncarcinogenic, stability |
| 09/28/2010 | US7803936 Compounds and methods for labeling oligonucleotides |
| 09/28/2010 | US7803934 Parallel preparation of high fidelity probes in an array format |
| 09/28/2010 | US7803788 Phosphoramidate linkages; retroviral or hepadnaviral therapy; tissue targeted therapy; HIV/aquired immunodeficiency syndrome; antitumor agents; improved bioavailability |
| 09/28/2010 | US7803786 Pharmaceutical co-crystal compositions and related methods of use |
| 09/28/2010 | US7803785 gemcitabine derivative containing 3* hydroxy-4*-hydroxymethyl substitution in furan ring and pyrimidine ring having substitution HNC(=O)CH3; treat or prevent diseases or disorders such as cancer or viral infections |
| 09/28/2010 | US7803777 conjugates of polyoxyethylene glycol with diverse therapeutic agents, e.g., peptides, lipids, glycolipids and small molecules; utility in biotechnology and medicine |
| 09/28/2010 | CA2382631C Poly(ether-thioether), poly(ether-sulfoxide) and poly(ether-sulfone) nucleic acids |
| 09/23/2010 | WO2010107487A2 Lipid-drug conjugates for drug delivery |
| 09/23/2010 | WO2010106320A2 Isolation and purification of components of whey |
| 09/23/2010 | US20100240883 Lipid-drug conjugates for drug delivery |
| 09/23/2010 | US20100240604 Protected nucleotide analogs |
| 09/23/2010 | CA2755729A1 Isolation and purification of components of whey |
| 09/21/2010 | US7799908 N6-Hydroxy-9H-(2'- beta -C-methyl- beta -D-ribofuranosyl)purine ; prepared from a precursor with an electrophilic center that is reacted with a dual nucleophilic reagent under conditions such that the reaction product is formed with high stereoselectivity |
| 09/21/2010 | US7799907 reacting a 1-halo ribofuranose compound with a nucleobase to obtain a nucleoside with removal of a silyl halide ((alkyl)3SiX (X=halide)); and deprotecting the nucleoside non-small cell lung (NSCLC), pancreatic, bladder, breast or ovarian cancers |
| 09/21/2010 | US7799762 Functionally substituted amino acids, having fatty acid chains bound through amidification of the amine functional groups of dipeptide like compounds, one end bears a functional side chain and other side neutral or charged acid |
| 09/21/2010 | US7799524 methods of transferring a label from novel substrates to O6-alkylguanine-DNA alkyltransferases (AGT) and O6-alkylguanine-DNA alkyltransferase fusion proteins, and to novel substrates suitable in such methods |
| 09/16/2010 | US20100234585 Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives |
| 09/16/2010 | US20100234584 2'-Fluorine-4'-Substituted-Nucleoside Analogues, Preparation Methods and Uses Thereof |
| 09/16/2010 | US20100234451 Lna antagonists targeting the androgen receptor |
| 09/16/2010 | US20100234444 Hindered ester-based biodegradable linkers for oligonucleotide delivery |
| 09/16/2010 | US20100234316 Nucleoside Aryl Phosphoramidates for the Treatment of RNA-Dependent RNA Viral Infection |
| 09/16/2010 | US20100233806 Carbocyclic bicyclic nucleic acid analogs |
| 09/16/2010 | US20100233678 Tunable affinity ligands for the separation and detection of target substances |
| 09/15/2010 | EP2227482A1 2',4'-substituted nucleosides as antiviral agents |
| 09/15/2010 | EP2227481A2 Antiviral nucleoside compounds |
| 09/15/2010 | EP1758596B9 Purine derivatives as adenosine a1 receptor agonists and methods of use thereof |
| 09/15/2010 | CN1911237B Beta - l-2'-deoxy-nucleosides for the treatment of hepatitis b |
| 09/15/2010 | CN101831478A Preparation method of 5'-acylate uridine and application in preparing medicaments for treating heart diseases and liver diseases |
| 09/15/2010 | CN101830955A Synthesizing process of antineoplastic agent clofarabine |
| 09/15/2010 | CN101830954A Method for extracting active ingredient of cordycepin from fruiting bodies of cordyceps militaris |
| 09/15/2010 | CN101830953A Method for preparing capecitabine and intermediate thereof |
| 09/15/2010 | CN101830952A Preparation method of 2',3'-O-diacetyl-5'-deoxidation-5-flurocitabine |
| 09/15/2010 | CN101830937A Visualized double-reaction tube fluorine-18 multifunctional automated synthesis module |
| 09/14/2010 | US7795424 Labelled nucleotides |
| 09/14/2010 | US7795238 β-L-2′-deoxy-nucleosides for the treatment of hepatitis B |
| 09/14/2010 | US7795236 8-(4'-Methylbiphenyl-4-ylmethylamino)adenosine; useful for the prevention or treatment of gout, hyperuricemia, urinary lithiasis, hyperuricemic nephropathy |
| 09/14/2010 | US7795042 red-emitting fluorescent rhodamine dyes; photostable; useful as molecular probes; For use in assays involving staining of cells, protein binding, and/or analysis of nucleic acids (hybridization and sequencing) |
| 09/14/2010 | US7794945 Conjugates between a minor groove binding the trimer of 1,2-dihydro- (3H)-pyrrolo(3,3-e)indole-7-carboxylate and an oligonucleotide and forms stable hybrids with complementary target sequence |
| 09/14/2010 | CA2347913C Oral administration of adenosine analogs |
| 09/10/2010 | WO2010101951A1 Nucleic acid chemical modifications |
| 09/10/2010 | WO2010101526A1 A diguanylate cyclase, method of producing the same and its use in the manufacture of cyclic-di-gmp and analogues thereof |
| 09/10/2010 | WO2010101061A1 Nucleoside-type antibiotic derivative |
| 09/10/2010 | WO2009116067A3 Novel derivatives of acyl cyanopyrrolidines |
| 09/10/2010 | CA2753975A1 Nucleic acid chemical modifications |
| 09/09/2010 | US20100227834 Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy |
| 09/09/2010 | US20100227833 Novel nucleoside analogs for treatment of viral infections |
| 09/09/2010 | US20100227831 Compositions and methods for cancer treatment |
| 09/09/2010 | US20100227327 Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides |
| 09/08/2010 | EP2226330A1 Charge-switch nucleotides |
| 09/08/2010 | EP2225255A1 Crystal forms of 2-[2-(4-chlorophenyl)ethoxy]adenosine |
| 09/08/2010 | EP2225228A2 Method of obtaining of 4-n-furfurylcytosine and/or its derivatives, an anti-aging composition and use of 4-n-furfurylcytosine and/or its derivatives in the manufacture of anti-aging composition |
| 09/08/2010 | CN101827856A 2 ' -flu0r0-2 ' -deoxytetrahydrouridines as cytidine deaminase inhibitors |
| 09/07/2010 | US7792576 Method of treatment for central nervous system injury |
| 09/07/2010 | US7790869 Massive parallel method for decoding DNA and RNA |
| 09/07/2010 | US7790703 New phosphonate ester derivatives of purine or pyrimidine antivirals; side effect reduction, less toxic, bioavailability |
| 09/07/2010 | US7790698 2-Alkoxyadeosine or 2-alkoxy-3'-deoxyadenosine where the alkoxy contains 1-4 carbon atoms; particularly 2-methoxy-adenosine (spongosine) or salt; antiinflammatory agents; side effect reduction, particularly, cardiovascular disorders such as bradycardia and tachycardia |
| 09/07/2010 | CA2465264C Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines |
| 09/07/2010 | CA2259156C Truncated soluble tumor necrosis factor type-i and type-ii receptors |
| 09/02/2010 | WO2010098365A1 Nucleoside-type antibiotic |
| 09/02/2010 | WO2010027512A4 Rna synthesis - phosphoramidites for synthetic rna in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic rna at the 3' - end |
| 09/02/2010 | WO2009115893A3 Novel 2 ', 2 ', 3 ', 3 ' -tetrasubstiuted nucleoside derivatives |
| 09/02/2010 | WO2009039639A8 Nucleotide triphosphate with an electroactive label conjugated to the gamma phosphate |
| 09/02/2010 | US20100222565 Method of producing 2'-deoxy-5-azacytidine (decitabine) |
| 09/02/2010 | US20100222563 Method for modification of nucleotides in nucleic acid, and nucleic acid having modified nucleotide therein |
| 09/02/2010 | US20100222295 Anti-Viral Pyrimidine Nucleoside Derivatives |
| 09/02/2010 | US20100222275 Therapeutic agent for vitiligo and method of accelerating pigmentation |
| 09/02/2010 | US20100221213 Y-shape branched hydrophilic polymer derivatives, their preparation methods, conjugates of the derivatives and drug molecules, and pharmaceutical compositions comprising the conjugates |
| 09/01/2010 | EP2223931A1 Novel nucleic acid base pair |
| 09/01/2010 | EP1877415B1 New labelling strategies for the sensitive detection of analytes |
| 09/01/2010 | CN101821277A 四氢吡喃核酸类似物 Tetrahydropyran nucleic acid analogs |
| 08/31/2010 | US7786296 5'-O-(4,4'-dimethoxytrityl)-thymidine-3'-O-diisopropylsilyl-4-benzoylaminobutanoic acid triethylammonium; for the synthesis of a nucleic acid oligomer containing modified bases that are unstable under a basic condition |
| 08/31/2010 | US7786089 modulate an immune response through toll like receptors; 5'-TCGiTCGiTTCTC-Y-GiCTTGiCAAGiCT-5' (SEQ ID NO: 1), wherein X is a glycerol linker, Y is C3-1inker and Gl is 7-deazaguanosine |
| 08/31/2010 | US7785796 sequence determination of an immobilized target polynucleotide comprising monitoring the sequential incorporation of nucleotides complementary to the immobilized target polynucleotide; the nucleotides have a base that is linked to a detectable label via a cleavable linker; detection of the labels |
| 08/31/2010 | US7785782 Device and method for in-line blood testing using biochips |
| 08/26/2010 | WO2010096201A2 Synthesis of ara-2'-o-methyl-nucleosides, corresponding phosphoramidites and oligonucleotides incorporating novel modifications for biological application in therapeutics, diagnostics, g- tetrad forming oligonucleotides and aptamers |
| 08/26/2010 | WO2004028462A9 Method for the preparation of 2-halo-2'-deoxyadenosine compounds from 2'-deoxyguanosine |
| 08/26/2010 | US20100216991 Synthesis of spongosine |
| 08/26/2010 | US20100216984 Novel chromophoric silyl protecting groups and their use in the chemical synthesis of oligonucleotides |
| 08/26/2010 | US20100216983 Synthesis of locked nucleic acid derivatives |
| 08/26/2010 | US20100216982 Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation |
| 08/26/2010 | US20100216797 Preparation of thioarabinofuranosyl compounds and use thereof |
| 08/26/2010 | US20100216736 2'-cyanopyrimidine nucleoside compound |
| 08/26/2010 | US20100216122 Enzymatic nucleic acid synthesis: methods for direct detection of tagged monomers |
| 08/26/2010 | US20100215685 Acyl pseudodipeptides which carry a functionalized auxiliary arm |
| 08/25/2010 | EP2221377A1 Oligonucleotide compositions with enhanced efficiency |
| 08/25/2010 | EP2221347A1 Sulfonated diarylrhodamine dyes |
| 08/25/2010 | EP2221311A1 Novel nucleic acid base pair |
| 08/25/2010 | EP2221307A1 Purine derivatives as adenosine A1 receptor agonists and methods of use thereof |
| 08/25/2010 | EP2220090A1 Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein |
| 08/25/2010 | EP1658302B1 Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis c |
| 08/25/2010 | CN101812105A Cytarabine 5'-O-amino-acid ester, salts thereof and preparation method thereof |
| 08/25/2010 | CN101812104A New method for continuously operating to synthesize capecitabine |
| 08/24/2010 | US7781576 contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-1,5-lactone with a fluorinating agent under anhydrous conditions and converting the precursor into a protected 2-deoxy-2-halo-2-C-disubstituted ribono-1,5-lactone |
| 08/24/2010 | US7781163 for drug screening enzyme inhibitors; solid phase synthesis; fluorescence resonance energy transfer (FRET) |
| 08/19/2010 | WO2010093608A1 Carba-nucleoside analogs for antiviral treatment |