Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
03/2003
03/20/2003US20030054028 Sustained releasing drug in situ
03/20/2003CA2459469A1 Pharmaceutical composition for diabetic neuropathy
03/19/2003EP1292604A1 2-aminocarbonyl-9h-purine derivatives
03/19/2003EP1292603A2 Methods and compositions for treating hepatitis c virus
03/19/2003EP1292313A2 Methods for treating hepatitis delta virus infection with beta-l-2' deoxy-nucleosides
03/19/2003EP1278528A4 Nucleoside analogs with carboxamidine-modified bicyclic base
03/19/2003EP1257281A4 Nucleoside analogs with carboxamidine modified monocyclic base
03/19/2003EP0902788B1 Nucleoside derivatives, and their use in oligonucleotide synthesis
03/18/2003US6534651 Substituted isoindolinone derivatives
03/18/2003US6534486 With broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2a receptor are described.
03/18/2003US6534481 Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin
03/18/2003CA2194153C Methods of screening for nucleoside analogs that are incorporated by hiv reverse transcriptase and cause incorrect base pairing
03/18/2003CA2190588C Pteridine nucleotide analogs as fluorescent dna probes
03/13/2003WO2003020985A1 Detection of genetic sequences using a bipartite probe
03/13/2003WO2003020984A2 Terminal-phosphate-labeled nucleotides and methods of use
03/13/2003WO2003020891A2 Single nucleotide amplification and detection by polymerase
03/13/2003WO2003020739A2 Novel lna compositions and uses thereof
03/13/2003WO2003020738A1 4'-deoxy-4'-(s)-amino avermectin derivatives
03/13/2003WO2003020734A2 Labeled nucleoside polyphosphates
03/13/2003WO2002100354A3 Pyrrolo[2,3-d]pyrimidine nucleoside analogs
03/13/2003WO2002032912A3 Phosphinoamidite carboxylates and analogs thereof in the synthesis of oligonucleotides having reduced internucleotide charge
03/13/2003WO2002020150A3 Photocleavable protecting groups
03/13/2003US20030050471 Antibiotic for use in the treatment and prevention of infections
03/13/2003US20030050458 Composition for use in the separation of preferential biopolymers from sample
03/13/2003US20030050454 Oligonucleotide sfor use in the treatment of cancer and viral diseases
03/13/2003US20030050320 A therapeutic agent for treating hepatitis C, based on polymerase inhibitory activity
03/13/2003US20030050284 Administering to a subject before the onset of an ischemic episode at daily dosages of 1-2 g of free cdp-choline
03/13/2003US20030050275 Partial and full agonists of A1 adenosine receptors
03/13/2003US20030050259 Method and reagent for the treatment of cardiac disease
03/13/2003US20030050229 Treatment with a 1' 2' and/or 3' nucleoside or a pharmaceutically acceptable salt or prodrug; nontoxic
03/13/2003US20030049632 Electronically mediated nucleic acid amplification in NASBA
03/13/2003US20030049201 Nucleosides for imaging and treatment applications
03/13/2003CA2774344A1 Terminal-phosphate-labeled nucleotides and methods of use
03/13/2003CA2457683A1 4"-deoxy-4"-(s)-amino avermectin derivatives
03/13/2003CA2457513A1 Labeled nucleoside polyphosphates
03/13/2003CA2456906A1 Single nucleotide amplification and detection by polymerase
03/12/2003EP1291354A2 Nucleotide compounds having a cleavable linker
03/12/2003EP1290006A1 Combinatorial production of nucleotide and nucleoside (xitp)analogues
03/12/2003EP1289911A2 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use
03/12/2003EP1289561A2 Ligand conjugates and methods for preparing same
03/12/2003EP1289521A2 Combination of lipoic acid and c 1 donors for the treatment of disorders of the central nervous system
03/12/2003EP1019426B1 Novel a1 adenosine receptor agonists and antagonists
03/12/2003EP0991412B1 Aminoacyl sulfamides for the treatment of hyperproliferative disorders
03/12/2003EP0842942B1 D-pentofuranose derivatives and process for the preparation thereof
03/12/2003EP0686160A4 Solution and solid-phase formation of glycosidic linkages
03/12/2003CN1402732A Nb heterocyclic 8-modified adenosine derivs.
03/12/2003CN1402724A Thiazolidinedione derivs. as antidiabetic agents
03/11/2003US6531589 Deprotection under mild conditions; stable protecting groups; use improved routes of oligonucleotide synthesis
03/11/2003US6531584 Nuclease resistant oligonucleotide analogs; DNA or RNA modulation; diagnosis, thearpy of viral diseases
03/11/2003US6531581 Purines and pyrimidines linked to a quencher
03/11/2003US6531505 Flavanoids or chromones of given formula that inhibit activated T cells; used for treating autoimmune disease, inflammatory reaction, fibrosis, transplant rejection, graft versus host disease, or allergic disease
03/11/2003US6531457 A2A adenosine receptor antagonists such as methyl-4-(3-(9-(5-(N-ethylcarbamoyl)-3,4-dihydrooxolan-2-yl)-6-aminopurin-2 -yl))prop-2-ynyl)cyclohexane-carboxylate
03/06/2003WO2003018599A1 1-(2,5'-anhydro-lyxofuranosyl) thymines for the synthesis of radiomarked fluoro-3 deoxynucleotides
03/06/2003WO2003018030A1 Mutagenic nucleoside analogs for the treatment of viral disease
03/06/2003US20030045705 Backbone modified oligonucleotide analogues
03/06/2003US20030045698 Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds
03/06/2003CA2458408A1 Mutagenic nucleoside analogs for the treatment of viral disease
03/05/2003EP1287532A2 Method for producing ?18 f]fluoride ion
03/05/2003EP1287404A1 Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
03/05/2003EP1287154A1 Charge-switch nucleotides
03/05/2003EP1287012A1 Nucleotide analogues comprising a reporter moiety and a polymerase enzyme blocking moiety
03/05/2003EP1286695A1 Antigenic composition comprising a polycationic peptide and inosine and cytosine
03/05/2003EP1001962B8 Production of avermectin compounds
03/05/2003CN1400976A Process for preparing indolopyrrolocarbazole derivatives, intermediates therefor, and preparation process of the intermediates
03/05/2003CN1400975A 嘌呤衍生物 Purine derivatives
03/04/2003US6528640 Synthetic ribonucleic acids with RNAse activity
03/04/2003US6528639 Active ribozyme
03/04/2003US6528631 Folates are conjugated to an oligonucleotide including at the 2'-, 3'-, 5'-, nucleobase and internucleotide linkage sites; improved transfer across cellular membranes; regioselective synthesis
03/04/2003US6528495 Aryl phosphate derivatives of d4T having anti-HIV activity
03/04/2003US6528494 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
02/2003
02/27/2003WO2003015798A1 Novel virus proliferation inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue
02/27/2003WO2003015516A1 Compositions and methods for treatment of mitochondrial diseases
02/27/2003WO2002086088A3 Polymerases with charge-switch activity and methods of generating such polymerases
02/27/2003WO2002072869A3 Novel agents for replacement of nad+/nadh system in enzymatic ractions
02/27/2003WO2002069903A3 Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
02/27/2003US20030040618 Compound for use as linking group in solid phase synthesis
02/27/2003US20030040502 Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
02/27/2003US20030039997 Pentopyranosyl nucleic acid arrays, and uses thereof
02/27/2003US20030039977 Carbamate-derivatized nucleosides and oligonucleosides
02/27/2003CA2456292A1 Novel virus growth inhibitor and/or virucidal method, and novel pyrazine nucleotide or pirazine nucleoside analog
02/26/2003EP1284984A1 Uridine derivatives as antibiotics
02/26/2003EP1284741A2 3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections
02/26/2003EP1284720A2 Method of treating hepatitis delta viral infection
02/26/2003EP1141409A4 A system and methods for nucleic acid sequencing of single molecules by polymerase synthesis
02/26/2003EP1019423B1 Method for producing a pentopyranosyl nucleoside
02/26/2003CN1399561A Conjugate having cleavable linkage for use in liposome
02/26/2003CN1398873A Dinucleotide for treating pulmonary tuberulosis
02/25/2003US6525191 Conformationally constrained L-nucleosides
02/25/2003US6525183 Solid-support, a cleavable linker, moiety with >/= three attachment sites, a label, a nucleophile and an acid cleavable protecting group reacted in a cyclical fashion with a phosphoramidate protected nucleoside
02/25/2003US6525033 2', 3' dideoxynucleoside compounds; 2',3'-dideoxycytidine (beta -L-FddC), beta -L-2',3'-dideoxy-5-fluorocytidine (beta-L-ddC); beta-D-2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-dioxolane
02/25/2003US6525032 Agonists of human adenosine receptors useful as anti-inflammatory agents in treatment of diseases of respiratory tract; chemical intermediates
02/20/2003WO2003014296A2 A group of novel anti-cancer compounds with specific structure
02/20/2003WO2003014139A1 Therapeutic compositions and screening methods relating to 3'-tyrosyl-dna-phosphodiesterase
02/20/2003WO2003014137A1 Adenosine a3 receptor agonists
02/20/2003US20030036649 2' modified oligonucleotides
02/20/2003US20030036527 Promoting mucociliary or cough clearance of retained mucus secretions from the lungs, sinuses, upper airways, ears, eyes, genitourinary tract, spermatozoa, ovaries, fallopian tubes, neutrophils, and macrophages
02/20/2003US20030036066 Linker phosphoramidites for oligonucleotide synthesis
02/20/2003CA2456744A1 Adenosine a3 receptor agonists
02/20/2003CA2456144A1 A group of novel anti-cancer compounds with specific structure
02/19/2003EP1283845A1 Process for the preparation of pharmaceutically acceptable salts of (ss-rs)-s-adenosyl-l-methionine