| Patents for C07D 473 - Heterocyclic compounds containing purine ring systems (11,932) |
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| 05/22/2008 | US20080119469 Novel Compounds |
| 05/22/2008 | US20080119466 1-(4-Chloro-3-(trifluoro-methyl)phenyl)-3-(4-imidazo-[4,5-c]pyridin-1-ylphenyl)urea; Raf, a serine-threonine protein kinase inhibitor; Raf/MEK/ERK cascade in proliferation of human cancer cells; anticarcinogenic agent; psoriasis, atherosclerosis, chronic rheumatoid arthritis and diabetes |
| 05/22/2008 | US20080119455 {2-[3-(4-Methyl-2-[2-methypropoxy]phenyl)-ureido]-thiazol-4-yl}-acetic acid ethyl ester; glucokinase inhibitor; antidiabetic, hypoglycemic agent; activators of glucokinase |
| 05/22/2008 | US20080119454 Aryl carbonyl derivatives as therapeutic agents |
| 05/21/2008 | CN101182322A Method for preparing antiviral drug of Entecavir |
| 05/21/2008 | CN101181277A Nucleotide analog composition and synthesis method |
| 05/20/2008 | US7375224 adenine modified solid, ordered, mesoporous, bifunctional, organo-inorganic silica-based catalyst; to obtain the desired product of cyclic carbonate |
| 05/20/2008 | CA2432223C Pyrazole compounds useful as protein kinase inhibitors |
| 05/15/2008 | WO2008056677A1 Reaction reagent for trifluoromethylation |
| 05/15/2008 | WO2008056150A1 Heterocyclyc sulfonamides having edg-i antagonistic activity |
| 05/15/2008 | WO2008056120A1 Adenine derivatives as inhibitors of hsp90 for the treatment of cancer |
| 05/15/2008 | US20080113993 Barbituric acid analogs as therapeutic agents |
| 05/15/2008 | CA2668785A1 Heterocyclyc sulfonamides having edg-i antagonistic activity |
| 05/15/2008 | CA2644333A1 Reaction reagent for trifluoromethylation |
| 05/14/2008 | EP1921056A1 Hydrogenation processes performed in ionic liquids |
| 05/13/2008 | US7371860 PNA monomer and precursor |
| 05/13/2008 | US7371859 Peptide nucleic acid monomers; 1-(4-(benzothiazolyl-, benzoxazolyl-, benzofuranyl-, and benzothiophenyl- sulfonyl)piperidin-3-one-1-ylcarbonylmethyl)adenines; suitable for automatic and parallel synthesis; increased yields |
| 05/13/2008 | US7371857 Synthesis for hydroxyalkylated heterocyclic bases |
| 05/13/2008 | US7371737 E.g., 2-nitro-6-trifluoromethyl-9-methyl purine; 2-morpholinyl-6-fluoromethyl-9- beta -D-ribofuranosyl purine; 6-trifluoromethyl-9-methyl-2-benzylamino purine; intermediates; preparation |
| 05/08/2008 | US20080108801 Conjugated lipophilic group with a modified nucleotide is used to target disease gene, cells, tissue, for drug delivery to entrance into tumor cells; ribose sugar of nucleotide is replaced with a cyclic carrier which has at least one attached phosphate or phosphorothioate group; antitumor biodrugs |
| 05/08/2008 | US20080108636 compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are told |
| 05/08/2008 | US20080108613 Pyrazolopyrimidine Compounds as Antitumor Agents |
| 05/06/2008 | US7368437 Bicyclic heterocycles, processes for their preparation and their use as herbicides and pharmaceutical agents |
| 05/02/2008 | WO2008051826A2 Purines as pkc-theta inhibitors |
| 05/02/2008 | WO2008051494A1 Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors |
| 05/02/2008 | CA2666940A1 Purines as pkc-theta inhibitors |
| 05/02/2008 | CA2666624A1 Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors |
| 05/01/2008 | US20080103304 Non-nucleotide composition and method for inhibiting platelet aggregation |
| 05/01/2008 | US20080103303 Chemical Synthesis Of S-Adenosyl-L-Methionine With Enrichment Of (S,S)-Isomer |
| 04/30/2008 | EP1727814B1 Nucleoside analogues with antiviral activity |
| 04/30/2008 | CN100384844C Xanthine phosphodiesterase V inhibitor polymorphs |
| 04/24/2008 | WO2008047201A2 Solid dispersion comprising a poorly water soluble drug |
| 04/24/2008 | US20080097097 Process for Preparing Purine Compounds |
| 04/24/2008 | US20080096903 inhibitors of disease-related target, Heat Shock Protein 90 (HSP90); antiproliferative; 2-chloro-5'-sulfamoyladenosine analogs; derivatives of adenine and other purines; Sulfamic Acid 2-[6-amino-2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-purin-9-yl]-ethyl ester |
| 04/24/2008 | CA2666664A1 Sulfamoyl-containing derivatives and uses thereof |
| 04/23/2008 | EP1912998A1 Pyrazole derivatives having tyrosinkinase activity |
| 04/23/2008 | EP1912994A1 Adenine derivatives |
| 04/23/2008 | EP1912993A1 Xanthine derivatives as selective hm74a agonists |
| 04/23/2008 | EP1912992A1 Xanthine derivatives as selective hm74a agonists |
| 04/23/2008 | EP1912991A1 Xanthine derivatives as selective hm74a agonists |
| 04/23/2008 | EP1912990A1 Hydrochlorides and hydrates of 1-[(3-cyanopyridin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-aminopiperidin-1-yl)xanthine, their preparation and their use as medicaments |
| 04/23/2008 | EP1912966A2 2-oxo-1-pyrrolidine derivatives and their therapeutic use on the central nervous system |
| 04/23/2008 | CN100383148C Nucleotide analog composition and synthesis method thereof |
| 04/22/2008 | US7361661 3-isobutyl-8-(6-methoxy-isoquinolin-4-ylmethyl)-1-methyl-3, 7-dihydro-purine-2,6-dione; sexual dysfunction, premature labour, dysmenorrhoea, benign prostatic hyperplasia, bladder outlet obstruction, incontinence, (Prinzmetal) angina, hipotensive agent |
| 04/17/2008 | US20080091010 Induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; antiviral and antitumor agents |
| 04/17/2008 | US20080090849 Protein kinase inhibitors, in particular inhibitory properties for CIV1 protein; N2-(4-aminocyclohexyl)-N6-(2-aminoethyl)-1H-purine-2,6-diamine trihydrochloride; fungal diseases such as candidiases, aspergilloses, histoplasmoses and coccidoidoses; fungicidal infections |
| 04/17/2008 | US20080090845 Haloalkyl-substituted pyrimidinone derivatives |
| 04/17/2008 | US20080090803 Fatty alcohol drug conjugates |
| 04/16/2008 | EP1911760A1 Xanthine oxidase inhibitor |
| 04/15/2008 | US7358235 Nitrobenzylthioinosine compounds for relief of pain |
| 04/15/2008 | US7358073 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4- pyrimidinyl)-amino-2-cyclopentenyl-1-methanol |
| 04/10/2008 | WO2008043031A1 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| 04/10/2008 | WO2008043019A1 8-substituted 2-(benzimidazolyl) purine derivatives for immunosuppression |
| 04/10/2008 | WO2008002959A3 Hiv integrase inhibitors |
| 04/10/2008 | WO2007121918A3 Use of 2-(purin-9-yl)-tetrahydofuran-3,4-diol derivatives as adenosine a2a receptor agonists |
| 04/10/2008 | WO2007110868A3 Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
| 04/10/2008 | US20080085909 Protein kinase C (PKC); rheumatoid arthritis, lupus, transplant rejection, asthma, inflammatory bowel disease, cancer and diabetes; for example, 2-(pyrrolidin-3-ylmethylamino)-9-(2-trifluoromethoxybenzyl)-7,8-dihydro-9H-purin-8-one |
| 04/10/2008 | US20080085908 A2b adenosine receptor antagonists |
| 04/10/2008 | US20080085907 Reverse transcriptase inhibitors; use against HIV with drug resistance to NNRTI's (Non Nucleoside Reverse Transcriptase Inhibitor drugs); Diaryl Pyrrolo(2,3-d)pyrimidines, diaryl purines, diaryl v-triazolo(4,5-d)pyrimidines |
| 04/09/2008 | EP1907391A1 Novel process for acyclic phosphonate nucleotide analogs |
| 04/09/2008 | CN100379746C Process for preparing the antiviral agent [1s-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6h-purin-6-one |
| 04/09/2008 | CN100379737C Thioxanthine derivatives as myeloperoxidase inhibitors |
| 04/09/2008 | CN100379736C Preparation process of entecavir |
| 04/08/2008 | US7355043 Such as 2-amino-6-chloro-9-(methyl-2-carbomethoxybutanoate-4-yl)purine, famciclovir, and penciclovir; for production of nucleosides |
| 04/08/2008 | CA2271126C Method of treating bronchitis with uridine triphosphates and related compounds |
| 04/03/2008 | WO2008037760A1 Process for the preparation of abacavir |
| 04/03/2008 | US20080081816 Anti-inflammation activity of newly synthesized xanthine derivatives kmup-1 and kmup-3 |
| 04/03/2008 | CA2662586A1 Process for the preparation of abacavir |
| 04/02/2008 | EP1905772A1 Process for the preparation of abacavir |
| 04/01/2008 | US7351827 Substituted oxetanes, method of making, and method of use thereof |
| 04/01/2008 | US7351695 Topiramate sodium, topiramate lithium, topiramate potassium, or polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, and amorphous forms; seizures, obesity, neuropathic pain, affective disorders, tobacco cessation, chronic fatigue syndrome, drug addiction; highly soluble, bioavailability |
| 03/27/2008 | WO2007136668A9 N-benzoyl-and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists |
| 03/27/2008 | US20080076923 preparation of valgancyclovir which comprises:a) reacting a compound of formula 7,** Image-1in an aprotic solvent, in the presence of a condensing agent, with a compound of formula 8, and freeze drying |
| 03/27/2008 | US20080076774 Kinase Modulators and Methods of Use |
| 03/27/2008 | US20080076132 Using enzyme inhibitors in combination chemotherapeutic agents to enhance therapeutic outcomes associated with cell proliferative disorers |
| 03/26/2008 | EP1903044A1 Adenosine Derivatives as A2A Receptor Agonists |
| 03/26/2008 | EP1509524B1 Xanthine phosphodiesterase v inhibitor polymorphs |
| 03/26/2008 | EP1509218A4 Peptide deformylase inhibitors |
| 03/26/2008 | CN101151254A Diketo acids with nucleobase scaffolds: anti-HIV replication inhibitors targeted at HIV integrase |
| 03/26/2008 | CN101148450A Preparation method for nucleoside compounds |
| 03/26/2008 | CN101148449A Salification method for 2-(6-quinolineamino)-6-cyclopropylamino-9H-purine |
| 03/26/2008 | CN101148448A Method for preparing N2-quinoline substituted purine derivative |
| 03/26/2008 | CN100376573C 1,3-dihydroimidazole fused-ring compound |
| 03/26/2008 | CN100376570C Dioxolane analogs for improved inter-cellular delivery |
| 03/26/2008 | CN100376569C Inhibitors of farnesyl protein transferase |
| 03/25/2008 | US7348339 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent |
| 03/20/2008 | WO2008031875A1 Adenosine derivatives as a2a receptor agonists |
| 03/20/2008 | WO2006000883A3 Chemical synthesis of s-adenosyl-l-methionine with enrichment of (s,s)-isomer |
| 03/20/2008 | US20080070934 Kw-3902 conjugates that do not cross the blood-brain barrier |
| 03/20/2008 | US20080070933 Purine, Pyrimidine, and Azaindole Derivatives |
| 03/20/2008 | US20080070914 Inhibitors of cell cycle kinases such as cyclin dependent kinase CDK4 and/or the Aurora kinases; use in combination with an anticancer agent |
| 03/20/2008 | US20080070894 Anticancer agents; PLK1 inhibitors; PLK=polo-like kinase; imidazo(1,2-a)pyridines such as 5-bromo-4-[8-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[(1S)-1-phenylethyl]-2-pyrimidinamine |
| 03/20/2008 | CA2662104A1 Adenosine derivatives as a2a receptor agonists |
| 03/19/2008 | EP1691813B1 Ready-for-use injectable solution of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amine-1h-purin-6(9h)-one, sterile, stable; closed system for packing the solution, process for eliminating alkaline residuals of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amine-1h-purin-6(9h)-one crystals; |
| 03/18/2008 | US7345170 Crystal and solvate of 2-amino-6-benzyloxypurine and production methods thereof |
| 03/13/2008 | WO2007148185A3 Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors |
| 03/13/2008 | US20080064705 Theophylline-based nitophenylpiperazine derivatives for enhancing aortic smooth muscle relaxation |
| 03/12/2008 | EP1897882A1 N2-quinolyl or isoquinolyl substituted purine derivatives, the preparation and uses thereof |
| 03/12/2008 | EP1895841A2 Methods for selective n-9 glycosylation of purines |
| 03/12/2008 | EP1404675B1 Dpp-iv-inhibiting purine derivatives for the treatment of diabetes |