Patents for C07D 459 - Heterocyclic compounds containing benz [g] indolo [2, 3-a] quinolizine ring systems, e.g. yohimbine; 16, 18-lactones thereof, e.g. reserpic acid lactone (97) |
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04/16/2014 | CN102627641B Method for extracting multiple alkaloids from rauvolfia vomitoria |
03/26/2014 | CN103664974A Aryl [a] indole [2,3-g] quinolizine compound as well as preparation method, pharmaceutical composition and application thereof |
01/16/2014 | WO2014009222A1 Combination therapy for the treatment of cancer and immunosuppression |
07/03/2013 | CN102010409B Method for extracting and separating yohimbine from Africa yohimbe bark |
01/09/2013 | CN102863439A Method for extracting yohimbine hydrochloride from yohimbe barks |
01/02/2013 | CN102020641B Method for extracting ajmaline from Rauwolfia root bark |
12/19/2012 | CN101735214B Method for extracting ajmaline from devilpepper waste liquor |
11/29/2012 | WO2012042541A3 Method for predicting and modeling anti-psychotic activity using virtual screening model |
11/06/2012 | CA2560778C A process for the semisynthesis of deserpidine |
08/08/2012 | CN102627641A Method for extracting multiple alkaloids from rauvolfia vomitoria |
08/02/2012 | US20120197016 Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis |
05/09/2012 | CN102002039B Method for extracting yohimbine from yohimbine bark |
03/20/2012 | CA2363067C Compounds and methods to inhibit or augment an inflammatory response |
03/15/2012 | US20120065401 Methods to inhibit or augment an inflammatory response |
11/16/2011 | EP2386565A2 Compounds and methods to inhibit or augment an inflammatory response |
07/20/2011 | CN101623310B Method for extracting total alkali, reserpine and rutin from devilpepper |
05/18/2011 | CN101475570B Method for extracting hypotensor raw material alserin from davilpepper |
05/04/2011 | CN102040605A Method for extracting high-content yohimbine |
04/27/2011 | CN102030747A Preparation method for yohimbine |
04/20/2011 | CN102020641A Method for extracting ajmaline from Rauwolfia root bark |
04/13/2011 | CN102010409A Method for extracting and separating yohimbine from Africa yohimbe bark |
04/06/2011 | CN102002039A Method for extracting yohimbine from yohimbine bark |
06/16/2010 | CN101735214A Method for extracting ajmaline from devilpepper waste liquor |
07/08/2009 | CN101475570A Method for extracting hypotensor raw material alserin from davilpepper |
06/03/2009 | CN100494194C Method of extracting reserpine from davilpepper |
05/26/2009 | US7538223 Compounds, compositions and methods |
04/08/2009 | CN100475811C A process for the semisynthesis of deserpidine |
12/23/2008 | US7468438 Demethylation of reserpic acid lactone to give 11-O-demethyl reserpic acid lactone, converting to deserpidic acid lactone, hydrolysis to methyl deserpidate esterification of methyl deserpidate with trimethoxybenzoic acid to give deserpidine |
10/02/2008 | US20080242864 Process for the Semisynthesis of Deserpidine |
06/25/2008 | EP1737855B1 A process for the semisynthesis of deserpidine |
12/05/2007 | CN101081849A Technique for synthesizing ground shepping |
11/07/2007 | EP1852422A2 Nitrosated and nitorsylated alpha-andrenergic receptor antagonist compounds, compositions and their uses |
08/15/2007 | CN101016297A Method of extracting reserpine from davilpepper |
08/01/2007 | EP1018879B1 Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
03/21/2007 | CN1934110A A process for the semisynthesis of deserpidine |
01/03/2007 | EP1737855A1 A process for the semisynthesis of deserpidine |
09/14/2006 | WO2005095394A8 A process for the semisynthesis of deserpidine |
10/13/2005 | WO2005095394A1 A process for the semisynthesis of deserpidine |
08/25/2005 | US20050187222 Therapy for impotency, erectile dysfuction; benign prostatic hyperplasia; hypotensive agents; congestive heart failure; vision defects; neurodegenerative disorders; incotinence; cognition activators |
03/24/2005 | US20050065161 Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
08/11/2004 | CN1161097C Method and composition for causing skin lightening |
07/28/2004 | CN1515242A Method and composition for whiting skin |
02/04/2003 | US6514934 For treating sexual dysfunctions in males and females |
10/22/2002 | US6469065 Compound that donates, transfers or releases nitric oxide, elevates endogenous levels of nitric oxide |
10/03/2002 | US20020143007 Donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase; for use in therapy |
08/13/2002 | US6433182 Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses |
07/09/2002 | US6417162 Female impotence treated with heterocyclic compound containing nitro groups |
05/23/2002 | US20020061879 Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
01/02/2002 | EP1164848A1 Compositions and methods for preventing and treating sexual dysfunctions |
11/27/2001 | US6323211 Alpha.-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo |
10/10/2001 | EP1141011A2 Compounds and methods to inhibit or augment an inflammatory response |
09/25/2001 | US6294517 Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use |
06/27/2001 | EP1109542A1 Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use |
05/31/2001 | WO2000042071A3 Compounds and methods to inhibit or augment an inflammatory response |
12/13/2000 | CN1276715A Method and composition for causing skin lightening |
10/12/2000 | WO2000059304A1 Compositions and methods for preventing and treating sexual dysfunctions |
08/01/2000 | US6096295 Composition for causing skin lightening |
07/20/2000 | WO2000042071A2 Compounds and methods to inhibit or augment an inflammatory response |
07/20/2000 | CA2697598A1 Compounds and methods to inhibit or augment an inflammatory response |
07/19/2000 | EP1018879A1 Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
03/09/2000 | WO2000012075A1 Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use |
03/09/2000 | CA2339145A1 Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use |
11/30/1999 | US5994294 Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses |
08/03/1999 | US5932538 Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses |
04/01/1999 | WO1999015149A1 Method and composition for causing skin lightening |
04/01/1999 | CA2304452A1 Method and composition for causing skin lightening |
03/09/1999 | US5879665 Extract of johimbe tree bark and topical vehicle or carrier |
08/07/1997 | WO1997027749A1 NITROSATED AND NITROSYLATED α-ADRENERGIC RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS AND THEIR USES |
08/07/1997 | CA2244879A1 Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use |
08/03/1994 | EP0608604A1 Ajmaline to reduce elevated intraocular pressure |
08/02/1994 | US5334385 New alkaloid derivatives, their use and pharmaceutical formulations containing them |
05/03/1994 | US5308849 Ajmaline |
12/08/1993 | EP0573260A1 New alkaloid derivatives, their use and pharmaceutical formulations containing them |
10/13/1992 | CA1308720C Sulphonamides |
02/27/1991 | EP0413709A1 Fatty amino acids, and homo- and hetero-oligomers and conjugates thereof |
11/02/1989 | WO1989010348A1 Fatty amino acids, and homo- and hetero-oligomers and conjugates thereof |
11/29/1988 | US4788202 Sulphonamide derivatives as α2 -adrenoceptor antagonists |
10/13/1987 | CA1228026A1 Treatment for selective weight control |
03/11/1987 | EP0213793A2 Sulphonamides |
10/29/1985 | CA1195978A2 Hydroxyamino-eburnane derivatives and a process for the preparation thereof |
06/25/1985 | US4525359 Applying adrenergic stimulator to local area |
04/02/1985 | US4508715 Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs |
10/03/1984 | EP0120165A2 A preparation and a process for achieving regional weight control |
04/18/1984 | EP0105361A1 Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs |
10/27/1983 | WO1983003541A1 Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs |
06/14/1983 | CA1148157A1 Hydroxyamino-eburnane derivatives and a process for the preparation thereof |
08/17/1982 | US4345082 Process for the preparation of hydroxyamino-eburnane derivatives and octahydroindoloquinolizine intermediates |
12/09/1980 | US4238491 Method for treating hypertension with methylreserpate |
02/12/1980 | CA1071628A1 Indolo-quinolizines |
12/04/1979 | CA1067496A1 1-(2-cyano-ethyl)-1,2,3,4,6,7-hexahydro-12h-indolo(2,3-a) quinolizino compounds |
04/03/1979 | CA1051900A1 1-hydroxymethyl-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo(2,3-a)quinolizine compounds |
10/03/1978 | CA1039728A1 Reserpine derivatives |
10/04/1977 | US4052404 Indolo (2,3-α)quinolizines |
07/19/1977 | US4036841 Vasodilators |
08/31/1976 | US3978065 Hypotensive |
08/10/1976 | US3974164 Reserpic acid derivatives |
02/24/1976 | US3940387 Yohimbine derivatives, process for their preparation and their applications |