Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
03/2009
03/04/2009CN100465173C A selective kinase inhibitor
03/04/2009CN100465168C An oxdiazole derivative and an application thereof in electroluminescent materials
03/04/2009CN100465163C Cis-2,4,5-triaryl-imidazolines
03/03/2009US7498435 One amine is substituted with a fused heterocyclic ring and the other with a fused heterocyclic ring or phenyl ring, e.g., N2,N4-Bis(3,4-ethylenedioxyphenyl)-5-cyano-2,4-pyrimidinediamine; inhibit IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators such as histamine
03/03/2009US7498421 Antibody specific for 4-methyl-3-vinylmaleimide derivatives; photolabile degradation product of bilirubin or biliverdin; antiinflammatory agents, infections,systemic inflammatory response syndrome
03/03/2009US7498350 e.g. 3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyrid-3-yl)phenyl)-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one; methacillin resistant staphylococcus, streptococcus pneumoniae, Enterococcus faecium, Haemophillus influenzae, Moraxella catarrhalis and Linezolid resistant streptococcus pneumoniae
03/03/2009US7498346 Chemokine receptor binding compounds
03/03/2009US7498343 Mycobacterial inhibitors
03/03/2009US7498329 5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine di-S-camsylate useful for treating sexual, neurodegenerative and psychological disorders; 5-(2-(2-hydroxyethylamino)-1-hydroxyethyl)-2-(2,5-dimethyl-1-pyrrolyl)pyridine or salt intermediate
03/03/2009US7498328 Derivatives of sulphonamides, their preparation and use as medicaments
03/03/2009CA2258165C N-[4-(heteroarylmethyl)phenyl]-heteroarylamines
02/2009
02/26/2009WO2009026276A1 5- (4- (haloalkoxy) phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors
02/26/2009WO2009025983A2 Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
02/26/2009WO2009025265A1 Piperazine derivative
02/26/2009WO2009024905A1 Pyridine derivatives as s1p1/edg1 receptor modulators
02/26/2009WO2009024821A2 Oxadiazole derivatives as dgat inhibitors
02/26/2009WO2009024342A2 Novel microbiocides
02/26/2009WO2009023967A1 Process for converting 9-dihydro-13-acetylbaccatin iii into docetaxel or paclitaxel
02/26/2009WO2009009531A3 Pyrimidinecarboxamide derivatives for the treatment of hiv infections
02/26/2009WO2009005269A3 Pharmaceutical composition for preventintion and treatment of restenosis comprising isoxazole derivatives
02/26/2009WO2009003998A3 Antiproliferative compounds based on 5-membered heterocycles
02/26/2009WO2009001203A3 An improved process for the preparation of aprepitant
02/26/2009WO2008140553A3 Mapk/erk kinase inhibitors
02/26/2009US20090054663 Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls
02/26/2009US20090054644 Pyrrolidine aryl-ether as nk3 receptor antagonists
02/26/2009US20090054642 Novel benzamidine derivative, process for the preparation thereof and pharmaceutical composition comprising same
02/26/2009US20090054514 (3-Amino-6-phenyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone; antiprolifrative, anticarcinogenic, antitumor agent; lymphomas, sarcomas, and leukemias
02/26/2009US20090054505 such as 5-(3-((R)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid, used for the reduction of intraocular pressure and treament of glaucoma
02/26/2009US20090054502 Benzimidazole Derivative and Use as Angiotensin II Antagonist
02/26/2009US20090054495 4-Chloro-2-phenylsulfanyl-phenyl)-4-isopropoxy-benzenesulfonamide; inflammatory bowl disease such as Crohn's disease or Colitis
02/26/2009US20090054483 Substituted Quinolines as Inhibitors of Leukotriene Biosynthesis
02/26/2009US20090054479 Fused heterocyclic derivatives as ppar modulators
02/26/2009US20090054460 Piperazine derivatives and methods of use
02/26/2009US20090054453 Novel Tetralins as 5-HT6 Modulators
02/26/2009US20090054451 Use of Piperidine Derivatives as Agonists of Chemokine Receptor Activity
02/26/2009US20090054448 Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors
02/26/2009US20090054440 Quinoline derivatives as neurokinin receptor antagonists
02/26/2009US20090054437 Nitrocatechol Derivatives as Comt Inhibitors
02/26/2009US20090054436 anticarcinogenic compounds; ; N-(4-(2-Aminopyridin-4-yloxy)-3-fluorophenyl)-2-bromoisonicotinamide, trifluoroacetic acid salt; inhibit the protein tyrosine kinase activity of growth factor receptors like Hepatocyte growth factor
02/26/2009US20090054435 Phenoxyalkanoic Acid Compound
02/26/2009US20090054434 Isoquinolone derivatives as phosphodiesterase 10 inhibitors
02/26/2009US20090054431 Novel heterocycle compounds
02/26/2009US20090054430 Inhibitors of Protein Kinases
02/26/2009US20090054429 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
02/26/2009US20090054428 Novel pyrimidine derivatives 965
02/26/2009US20090054427 Aminobenzyl-substituted cyclic sulfones useful as bace inhibitors
02/26/2009US20090054425 Protein kinase inhibitors
02/26/2009US20090054420 Bicyclic-substituted amines as histamine-3 receptor ligands
02/26/2009US20090054411 4-anilinoquinoline-3-carboxamides as csf-1r kinase inhibitors
02/26/2009US20090054409 [4-(4-imidazo[1,2-a]pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-morpholin-4-yl-methanone, used for treating rheumatoid arthritis in mammals
02/26/2009US20090054407 such as 4-Methanesulfonyloxy-5-methoxy-7-[1H-5-(methylaminomethyl)indol-2-yl]isoindolinone, having an antitumor activity
02/26/2009US20090054405 PI3 kinase modulators and methods of use
02/26/2009US20090054402 7-substituted indole mcl-1 inhibitors
02/26/2009US20090054397 Pyrazole compounds and pharmaceutical compositions comprising the compound
02/26/2009US20090054395 focal adhesion kinase inhibitor, i.e. FAK inhibitor; tyrosine kinase inhibitors; cancer, osteoporosis; e.g. N-methyl-4-({4-[({3-[methyl(methylsulfonyl)amino]pyrazin-2-yl}methyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)benzamide hydrochloride
02/26/2009US20090054392 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
02/26/2009US20090054376 Benzofuran derivatives with therapeutic activities
02/26/2009US20090054352 Benzene derivative or salt thereof
02/26/2009US20090053328 Nitric Oxide Enhancing Glutamic Acid Compounds, Compositions and Methods of Use
02/26/2009US20090053172 Heterocyclic compounds as ccr5 antagonists
02/26/2009CA2697081A1 5-(4-(haloalkoxy)phenyl)pyrimidine-2-amine compounds and compositions as kinase inhibitors
02/26/2009CA2696856A1 Process for converting 9-dihydro-13-acetylbaccatin iii into docetaxel or paclitaxel
02/26/2009CA2695509A1 Pyridine derivatives as s1p1/edg1 receptor modulators
02/26/2009CA2695434A1 Chemical compounds 979
02/26/2009CA2693067A1 Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
02/25/2009EP2027143A2 Compounds and compositions as channel activating protease inhibitors
02/25/2009EP2027121A1 Cyclic amine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
02/25/2009EP2027120A2 Mglur5 modulators i
02/25/2009EP2027119A2 Ethers, secondary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
02/25/2009EP2027118A2 Polymorphs of (r)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-thione hydrochloride
02/25/2009EP2027110A2 Mglur5 modulators iii
02/25/2009EP2027090A2 Mglur5 modulators ii
02/25/2009EP1885695B1 Indoline compounds
02/25/2009EP1578726B1 Tetrahydroquinoline derivatives
02/25/2009EP1027056B1 Alpha-ketoamide multicatalytic protease inhibitors
02/25/2009CN101374834A Compounds and methods for modulating FXR
02/25/2009CN101374830A Alpha2C adrenoreceptor agonists
02/25/2009CN101374828A Heterocyclylalkyl derivatives as novel inhibitors of histone deacetylase
02/25/2009CN101374824A Heterocyclic GABA-B modulators
02/25/2009CN101374821A 3,5-di(aryl or heteroaryl)isoxazoles and 1,2,4-oxadiazoles as S1P1 receptor agonists, immunosuppresssive and anti-inflammatory agents
02/25/2009CN101374820A Piperazine compounds with a herbicidal action
02/25/2009CN101374818A Pyrimidine derivatives
02/25/2009CN101374817A Trisubstituted amine compound as inhibitors of cholesteryl ester transfer protein cetp
02/25/2009CN101374815A Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (HIF)
02/25/2009CN101374811A Novel dual nk2/nk3-antagonists, pharmaceutical compositions comprising them and processes for their preparations
02/25/2009CN101372474A 2-(1h-indolylsulfanyl)-benzyl amine derivatives as SSRI
02/24/2009US7495110 Benzimidazole derivatives and their use as GnRH antagonists
02/24/2009US7495109 Nociceptin analogs
02/24/2009US7495021 Benzothiazole- and benzooxazole-4,7-dione, derivatives and their use as cdc25 phosphate inhibitors
02/24/2009US7495020 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders
02/24/2009US7495016 inhibiting HIV replication in a cell; inhibiting reverse transcriptase
02/24/2009US7495014 Gyrase inhibitors and uses thereof
02/24/2009US7494998 Benzisoxazole piperazine compounds and methods of use thereof
02/24/2009US7494993 Enhanced activity, decreased toxicity, better solubility and improved pharmacokinetic profile; for inflammatory, immunological, CNS disorders, oncological disorders, bone diseases; Cyclohexanecarboxylic acid (4-chloro-3-{7-amino-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl}-phenyl)-amide
02/24/2009US7494990 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
02/24/2009CA2469813C Heteroaryl substituted pyrazole modulators of metabotropic glutamate receptor-5
02/19/2009WO2009023854A1 Bicyclic sphingosine 1-phosphate analogs
02/19/2009WO2009023752A1 Adrenergic compounds
02/19/2009WO2009023653A2 Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators
02/19/2009WO2009023233A1 Substituted oxazolidinone derivatives