Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
02/2010
02/10/2010EP1817287B1 Aromatic ether derivatives useful as thrombin inhibitors
02/10/2010EP1747196B1 Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
02/10/2010EP1411932B1 Substituted oxazolidinones for combinational therapy
02/10/2010CN101643471A C3/C3 fluoroquinolone dimmer derivative using oxadiazole as connection chain as well as preparation method and application thereof
02/09/2010US7659402 use as pain relievers, gastrointestinal disorders; 2-Amino-3-aryl-1-[3-((hetero)aryl)piperidin-1-yl]-propan-1-one compounds
02/09/2010US7659394 Substituted morpholine compounds for the treatment of central nervous system disorders
02/09/2010US7659314 PH-sensitive polymeric micelles for drug delivery
02/09/2010US7659298 2-(3-Phenyl-5-chloro-1-methyl-1H-pyrazol-4-ylmethylsulphanyl)-N-quinolin-3-ylbenzamide; 2-(3-Phenyl-5-chloro-1-methyl-1H-pyrazol-4-ylmethoxy)-N-naphthalin-2-ylbenzamide; obesity, including obesity of the non-insuline-dependent diabetes patients, sleeping disorders, stroke, nausea and vomiting
02/09/2010US7659294 2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as S1P receptor agonists
02/09/2010US7659280 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
02/09/2010US7659272 N-[phenyl or heteroaryl carbonoyl pyridyl] arylsulfonamides; antiinflammatory, antianaphylactic agents; transplant rejection, gastointestinal, respriatory system and skin disorders
02/09/2010US7659268 Modulators of ATP-binding cassette transporters
02/09/2010US7659265 5-(4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbothioamide; menopause therapy; contraceptive; anticancer agents
02/09/2010CA2439593C Heterocyclic compounds for aging-related and diabetic vascular complications
02/09/2010CA2274201C Di-or triaza-spiro[4,5]decane derivatives
02/09/2010CA2268403C Anthranilic acid derivatives as multi drug resistance modulators
02/09/2010CA2201863C Substituted 4-biarylbutyric or 5-biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
02/09/2010CA2192092C Arylsulfonamido-substituted hydroxamic acids as matrix metalloproteinase inhibitors
02/04/2010WO2010013222A1 Pyrrole carboxylic acid derivatives as antibacterial agents
02/04/2010WO2010013161A1 Fluorinated heteroaryls
02/04/2010WO2010013037A1 1,2,4-oxadiazole substituted piperidine and piperazine derivatives as smo antagonists
02/04/2010WO2010012740A1 5-alkynyl-pyrimidines
02/04/2010WO2010012620A1 Pyrrolidin-3-ylmethyl-amine as orexin antagonists
02/04/2010WO2010012619A1 Diazepan and piperazine derivatives modulators of chemokine receptors
02/04/2010WO2010012121A1 Aralkyl substituted piperidine or piperazine derivatives and their use for treating schizophrenia
02/04/2010WO2010012107A1 Selective glycosidase inhibitors and uses thereof
02/04/2010WO2009129267A3 Small molecule inhibitors of the pleckstrin homology domain and methods for using same
02/04/2010WO2009126003A3 Novel pyrazole and benzoxazole-substituted pyridine derivatives or pharmaceutically acceptable salts thereof, preparation process for same, and pharmaceutical composition for prevention and treatment of disorders involving aberrant cell proliferation containing same as active ingredients
02/04/2010US20100029950 Novel substituted 1h-dihydropyrazoles, their preparation and use
02/04/2010US20100029949 Activator for Peroxisome Proliferator Activated Receptor
02/04/2010US20100029938 Process for the preparation of an antibacterial quinolone compound
02/04/2010US20100029754 Thiophene-carboxamide derivatives and their use as inhibitors of the enzyme ikk-2
02/04/2010US20100029729 Compounds
02/04/2010US20100029728 Phosphodiesterase inhibitors
02/04/2010US20100029720 Carboxamide Derivatives As Muscarinic Receptor Antagonists
02/04/2010US20100029687 Piperidine derivative or salt thereof
02/04/2010US20100029685 Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
02/04/2010US20100029682 Novel chromene and thiochromene carboxamide derivatives, methods for preparing same and therapeutic applications of same
02/04/2010US20100029664 Pyrrolidin-3-ylmethyl-amine as orexin antagonists
02/04/2010US20100029653 Pyrazolopyridine, indazole, imidazopyridine, imidazopyrimidine, pyrazolopyrazine and pyrazolopyridine derivatives as stimulators of guanylate cyclase for cardiovascular disorders
02/04/2010US20100029650 Bicyclic compounds and use as antidiabetics
02/04/2010US20100029649 Phenyl-substituted pyrimidine compounds useful as kinase inhibitors
02/04/2010US20100029647 3,4,(5)-substituted tetrahydrophyridines
02/04/2010US20100029646 Prodrugs of diphenyl ox-indol-2-one compounds
02/04/2010US20100029645 Inhibitors of Cytosolic Phospholipase A2
02/04/2010US20100029644 Compounds Which Modulate The CB2 Receptor
02/04/2010US20100029643 Heterocyclyc sulfonamides having edg-1 antagonistic activity
02/04/2010US20100029640 Neuroprotective agents for the prevention and treatment of neurodegenerative diseases
02/04/2010US20100029638 Fused heterocyclyc inhibitor compounds
02/04/2010US20100029636 Lck inhibitors
02/04/2010US20100029635 6,7,8,9-substituted 1-phenyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones useful as anti-infective pharmaceutical agents
02/04/2010US20100029632 improved pharmacokinetics
02/04/2010US20100029628 2,4,5-Substituted Piperidines as Renin Inhibitors
02/04/2010US20100029620 Substituted triazoline, tetrazolone and imidazolone derivatives for use as a medicine
02/04/2010US20100029615 Benzimidazole derivatives
02/04/2010US20100029610 Heteroaryl Compounds and Uses Thereof
02/04/2010US20100029606 Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof
02/04/2010US20100029605 Compounds and compositions as protein kinase inhibitors
02/04/2010US20100029592 Deuterium-enriched fosaprepitant
02/04/2010US20100029589 4,5-dihydro-oxazol-2yl derivatives
02/04/2010CA2732618A1 Pyrrole carboxylic acid derivatives as antibacterial agents
02/04/2010CA2732336A1 Selective glycosidase inhibitors and uses thereof
02/04/2010CA2731909A1 5-alkynyl-pyrimidines
02/04/2010CA2731873A1 1,2,4-oxadiazole substituted piperidine and piperazine derivatives as smo antagonists
02/04/2010CA2731403A1 Pyrrolidin-3-ylmethyl-amine as orexin antagonists
02/04/2010CA2730770A1 Diazepan and piperazine derivatives modulators of chemokine receptors
02/04/2010CA2729581A1 Fluorinated heteroaryls
02/03/2010EP2149561A1 Tetrahydroisoquinolin-1-one derivative or salt thereof
02/03/2010EP2149550A1 Nitrogen-containing five-membered heterocyclic compound
02/03/2010EP2148878A1 Novel heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
02/03/2010EP2148877A2 Inhibitors of hypoxia inducible factor (hif) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
02/03/2010EP2148876A1 Pyrazolone derivatives as pde4 inhibitors
02/03/2010EP2148868A1 Novel aromatic heterocyclic carboxylic acid amide derivatives useful as potassium channel modulators
02/03/2010EP2148862A1 Dihydroquinone and dihydronaphthridine inhibitors of jnk
02/03/2010EP2148692A2 Melanocortin receptor ligands modified with hydantoin
02/03/2010EP2148677A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
02/03/2010EP1778677B1 Heterocyclic condensed compounds useful as antidiuretic agents
02/03/2010EP1511742B1 Kinase inhibitors
02/03/2010CN100586945C Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists
02/03/2010CN100586927C Amide derivatives and their use as inhibitors of 11-beta-hydroxysteroid dehydrogenase
02/02/2010US7655808 Leptomycin B; antiproliferative agents; antitumor agents; antcarcinogenic agents; inhibiting the export of a protein from the nucleus of a cell via a CRM1-mediated process; tissue-targeted therapy; cancer of human breast, lung, ovaries, prostate, and bladder, and leukemia cell
02/02/2010US7655798 crystallizing aripiprazole Type II from a solution of aripiprazole dissolved in a solvent selected from 2-propanol, dimethylsulfoxide or mixture and optionally further comprising ethyl acetate; solid state Type II aripiprazole without the use of a solid state heat treatment
02/02/2010US7655797 Intermediates for making 2,4-pyrimidinediamine compounds
02/02/2010US7655688 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
02/02/2010US7655684 1-(Urea-, thiourea- and cyanoguanidine-methylene)benzyl)imidaoles, treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson's disease and Huntington's disease
02/02/2010US7655679 Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions
02/02/2010US7655666 Substituted 1H-quinazoline-2,4-diones useful as AMPA receptor ligands
02/02/2010US7655663 (2S)-4,4-difluoro-1-(2-{[1-(2-pyrazinyl)piperidin-4-yl]amino}acetyl)-2-pyrrolidine carbonitrile; enzyme inhibitors; diabetes
02/02/2010US7655650 Oxadiazine derivatives
02/02/2010US7655649 Inhibitors of Akt activity
02/02/2010US7655645 Indole derivatives
02/02/2010US7655641 3-(4-{2-[(5-Fluoro-3- methyl-benzo[b]thiophene-2- sulfonyl)-propyl- amino]-ethylsulfanyl}- 2-methyl-phenyl)- propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, hypertension, arteriosclerosis and cardiovascular diseases
02/02/2010CA2516682C Imidazol-4-yl-ethynyl-pyridine derivatives
02/02/2010CA2485685C Calcium receptor modulating agents
02/02/2010CA2418868C 4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists
02/02/2010CA2358581C Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them
02/02/2010CA2333963C Carboxylic acids and carboxylic acid isosteres of n-heterocyclic compounds
02/02/2010CA2294809C Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same
01/2010
01/28/2010WO2010011853A2 Beta-and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
01/28/2010WO2010011657A1 Bicyclic heterocycle derivatives as histamine h3 receptor antagonists