Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
03/2009
03/04/2009EP2029581A1 P38 inhibitors and methods of use thereof
03/04/2009EP2029580A1 Novel indol-pyrrol derivatives for the treatment of proliferative and inflammatory diseases
03/04/2009EP2029579A2 Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
03/04/2009EP2029578A1 2-carbocycloamino-4-imidaz0lylpyrimidines as agents for the inhbition of cell proliferation
03/04/2009EP2029576A1 Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
03/04/2009EP2029558A2 Compounds and methods for modulating fxr
03/04/2009EP2029553A1 Substituted pyrazinone derivatives for use as a medicine
03/04/2009EP2029551A2 Pyridinone and pyridazinone derivatives as inhibitors of poly(adp-ribose)polymerase (parp)
03/04/2009EP2029550A2 1-sulfonylindazolylamine and -amide derivatives as 5-hydroxytryptamine-6 ligands
03/04/2009EP2029547A1 Fxr agonists
03/04/2009EP2029530A1 Ethenyl carboxamide derivatives useful as microbiocides
03/04/2009EP1899328B1 A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1h-imidazole-5-carbaldehydes
03/04/2009EP1706376B1 Imidazole derivatives, processes for preparing them and their uses
03/04/2009EP1660443B1 Cyclic amine bace-1 inhibitors having a benzamide substituent
03/04/2009EP1551812B1 Mitotic kinesin inhibitors
03/04/2009EP1485370B1 Amino-derivatives as novel inhibitors of histone deacetylase
03/04/2009EP1452527B1 Azabicyclo compound, matrix metalloprotease inhibitor, and skin preparation
03/04/2009EP1140908B1 Triazole compounds with dopamine-d3-receptor affinity
03/04/2009CN101379060A Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors
03/04/2009CN101379059A N-hydroxyacrylamide compounds
03/04/2009CN101379058A Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases
03/04/2009CN101379042A Substituted cinnoline derivatives as GABAA-receptor modulators and method for their synthesis
03/04/2009CN101379030A Sulfonamide derivatives to treat infection with hepatitis c virus
03/04/2009CN101379028A Chemical compounds
03/04/2009CN100465173C A selective kinase inhibitor
03/04/2009CN100465163C Cis-2,4,5-triaryl-imidazolines
03/03/2009US7498439 Synthesis of heteroaryl acetamides from reaction mixtures having reduced water content
03/03/2009US7498435 One amine is substituted with a fused heterocyclic ring and the other with a fused heterocyclic ring or phenyl ring, e.g., N2,N4-Bis(3,4-ethylenedioxyphenyl)-5-cyano-2,4-pyrimidinediamine; inhibit IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators such as histamine
03/03/2009US7498335 Method of producing an antiangiogenic or vascular permeability reducing effect
03/03/2009US7498328 Derivatives of sulphonamides, their preparation and use as medicaments
03/03/2009CA2258165C N-[4-(heteroarylmethyl)phenyl]-heteroarylamines
02/2009
02/26/2009WO2009026326A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
02/26/2009WO2009026319A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
02/26/2009WO2009026276A1 5- (4- (haloalkoxy) phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors
02/26/2009WO2009025823A1 Phosphodiesterase 10 inhibitors
02/26/2009WO2009025265A1 Piperazine derivative
02/26/2009WO2009024906A1 4-pyrimidinesulfamide derivative
02/26/2009WO2009024825A1 2-pyrazinylbenzimidazole derivatives as receptor tyrosine kinase inhibitors
02/26/2009WO2009024502A1 Pyrrolidine aryl-ether as nk3 receptor antagonists
02/26/2009WO2009024342A2 Novel microbiocides
02/26/2009WO2009024221A1 6-thioxo-pyridazine derivatives
02/26/2009WO2009024214A1 Process for the production of voriconazole
02/26/2009WO2009003998A3 Antiproliferative compounds based on 5-membered heterocycles
02/26/2009WO2008140553A3 Mapk/erk kinase inhibitors
02/26/2009WO2008005368A3 Piperazines as p2x7 antagonists
02/26/2009WO2007014226A3 Compounds for the treatment of neurodegeneration and stroke
02/26/2009US20090054645 Bridge compound with N, N-dialkylamino group and application thereof
02/26/2009US20090054644 Pyrrolidine aryl-ether as nk3 receptor antagonists
02/26/2009US20090054509 Octahydropentalene-Substituted Pyrazoline Derivatives, Their Prepartion and Use as Medicaments
02/26/2009US20090054466 Leukotriene B4 Inhibitors
02/26/2009US20090054465 N-hydroxyacrylamide compounds
02/26/2009US20090054462 Hydroisoindoline tachykinin receptor antagonists
02/26/2009US20090054460 Piperazine derivatives and methods of use
02/26/2009US20090054459 Substituted indoles
02/26/2009US20090054453 Novel Tetralins as 5-HT6 Modulators
02/26/2009US20090054450 Compositions and methods of use for treating or preventing lipid related disorders
02/26/2009US20090054449 Substituted N-heterocyclic Compounds and Their Use as Dopamine D3 Receptor Ligands
02/26/2009US20090054448 Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors
02/26/2009US20090054447 2,3 Substituted Pyrazine Sulfonamides as Inhibitors of CRTH2
02/26/2009US20090054445 Amide Substituted Quinolines
02/26/2009US20090054432 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors
02/26/2009US20090054429 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
02/26/2009US20090054423 Niacin receptor agonists, compositions containing such compounds and methods of treatment
02/26/2009US20090054420 Bicyclic-substituted amines as histamine-3 receptor ligands
02/26/2009US20090054409 [4-(4-imidazo[1,2-a]pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-morpholin-4-yl-methanone, used for treating rheumatoid arthritis in mammals
02/26/2009US20090054407 such as 4-Methanesulfonyloxy-5-methoxy-7-[1H-5-(methylaminomethyl)indol-2-yl]isoindolinone, having an antitumor activity
02/26/2009US20090054402 7-substituted indole mcl-1 inhibitors
02/26/2009US20090054397 Pyrazole compounds and pharmaceutical compositions comprising the compound
02/26/2009US20090054395 focal adhesion kinase inhibitor, i.e. FAK inhibitor; tyrosine kinase inhibitors; cancer, osteoporosis; e.g. N-methyl-4-({4-[({3-[methyl(methylsulfonyl)amino]pyrazin-2-yl}methyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)benzamide hydrochloride
02/26/2009US20090054392 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
02/26/2009CA2697325A1 Pyrrolidine aryl-ether as nk3 receptor antagonists
02/26/2009CA2697100A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
02/26/2009CA2697081A1 5-(4-(haloalkoxy)phenyl)pyrimidine-2-amine compounds and compositions as kinase inhibitors
02/26/2009CA2696472A1 6-thioxopyridazine derivatives
02/26/2009CA2695511A1 4-pyrimidinesulfamide derivative
02/25/2009EP2027120A2 Mglur5 modulators i
02/25/2009EP2027119A2 Ethers, secondary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
02/25/2009EP2027114A1 Maleate co-crystal of azd1152
02/25/2009EP2027113A1 Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes
02/25/2009EP2027110A2 Mglur5 modulators iii
02/25/2009EP2027096A1 Substituted arylimidaz0l0ne and triaz0l0ne as inhibitors of vasopressin receptors
02/25/2009EP2027088A2 Compounds for the treatment of spinal muscular atrophy and other uses
02/25/2009EP1885695B1 Indoline compounds
02/25/2009EP1027056B1 Alpha-ketoamide multicatalytic protease inhibitors
02/25/2009CN101374830A Alpha2C adrenoreceptor agonists
02/25/2009CN101374829A Inhibitors of IAP
02/25/2009CN101374820A Piperazine compounds with a herbicidal action
02/25/2009CN101374818A Pyrimidine derivatives
02/25/2009CN101374817A Trisubstituted amine compound as inhibitors of cholesteryl ester transfer protein cetp
02/25/2009CN101374808A Indole sulfonamide modulators of progesterone receptors
02/25/2009CN101374804A Substituted diphenylethers, -amines, -sulfides and -methanes for the treatment of respiratory disease
02/25/2009CN101372474A 2-(1h-indolylsulfanyl)-benzyl amine derivatives as SSRI
02/24/2009US7495110 Benzimidazole derivatives and their use as GnRH antagonists
02/24/2009US7495109 Nociceptin analogs
02/24/2009US7495016 inhibiting HIV replication in a cell; inhibiting reverse transcriptase
02/24/2009US7495014 Gyrase inhibitors and uses thereof
02/24/2009US7495012 Arylsulfonamides and uses related thereto
02/24/2009US7494997 excellent BCR-ABL tyrosine kinase inhibitory activity; to treat leukemias; 3-bromo-4-(4-methylpiperazin-1-ylmethyl)-N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]phenyl}benzamide; compounds with cell growth inhibitory effect
02/24/2009US7494989 Pyridine compounds useful as N-type calcium channel antagonists
02/24/2009CA2469813C Heteroaryl substituted pyrazole modulators of metabotropic glutamate receptor-5