Patents
Patents for C07D 309 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings (12,815)
11/2004
11/25/2004US20040235818 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
11/24/2004EP1478640A1 Process for the manufacture of hmg-coa reductase inhibitory mevalonic acid derivatives
11/24/2004EP1318976B1 Substituted aminopropoxyaryl derivatives useful as agonists for lxr
11/24/2004CN1176917C Prep. of pyrone compound
11/23/2004US6821963 4-Bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors
11/18/2004WO2004099132A2 Process for the preparation of trans-isomers of diphenylazetidinone derivatives
11/18/2004WO2004098582A2 Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions
11/18/2004US20040229924 Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/TACE inhibitors
11/18/2004US20040229915 Cysteine protease inhibitors
11/17/2004EP1476419A2 N-biphenylmethyl aminocycloalkanecarboxamide derivatives
11/17/2004EP1476416A2 Multifunctional monomers and their use in making cross-linked polymers and porous films
11/17/2004EP1210333B1 p-Tolyl-heterocycles as herbicides
11/17/2004EP1165538B1 Process for the preparation of alpha-methylenelactones and alpha-substituted hydrocarbylidene lactones
11/16/2004US6818789 Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
11/16/2004US6818775 Treatment of skin-related diseases or prevention of certain undesired side effects of administered retinoids
11/11/2004WO2004096789A1 Method of preparing statins intermediates
11/11/2004WO2004096788A1 Process fot the preparation of (4-hydroxy-6-oxo-tetrahydropyran-2-yl) acetonitrile and derivatives thereof
11/11/2004WO2004085344A3 Production of oxy-michael adducts
11/11/2004WO2004056745A3 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors
11/11/2004US20040224990 Enantioselective hydrogenation of intermediates in the synthesis of tipranavir
11/11/2004US20040224960 Pharmaceutical compositions and methods for their use
11/11/2004US20040224959 such as N-benzyl-3-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-N-methylbenzamide; for inhibition of secretion of apolipoprotein B lipoprotein from the liver; for treatment of hyperlipidemia, pancreatitis
11/11/2004US20040224904 Carbohydrate scaffold, carrying two side chains, which form a macrocyclic ring that may be unsaturated and contains ether, amide, ester and/or carbamate groups; for therapy of bacterial, fungal, viral or protozoal infections or tumors
11/11/2004CA2524457A1 Process fot the preparation of (4-hydroxy-6-oxo-tetrahydropyran-2-yl) acetonitrile and derivatives thereof
11/10/2004EP1475371A1 1-substituted-1-aminomethyl-cycloalkane derivatives (= gabapentin analogues), their preparation and their use in the treatment of neurological disorders
11/10/2004EP1474411A2 Improved process for the production of dihydropyridines
11/10/2004EP1474098A1 Sunscreen compositions as well as dihydropyridines and dihydropyranes
11/10/2004CN1174974C Synthesis of ester ether compound with high acidolysis activity
11/04/2004WO2004094412A1 Nk-2 antagonist basic linear compounds and formulations containing them
11/04/2004WO2004080377A3 Kcnq channel modulating compounds and their pharmaceutical use
11/04/2004CA2523200A1 Nk-2 antagonist basic linear compounds and formulations containing them
11/03/2004EP1473291A1 Process for producing lactone
11/03/2004EP1473275A1 Metallized mesoporous silicate and method of oxidation with the same
11/03/2004EP1472244A1 Aromatic sulfone hydroxamic acids and their use as protease inhibitors
11/03/2004CN1543468A Processes for preparing calcium salt forms of statins
11/03/2004CN1173947C 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides
11/03/2004CN1173913C Method of using easy removed nitroxyl selective alcohol axide
11/02/2004US6812227 Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
10/2004
10/28/2004US20040214890 1,3-diamino-2-hydroxypropane derivatives are useful as inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal
10/28/2004US20040214887 for example, 6,9-Dihydroxy-2,2,13,13-tetramethyl-tetradecanedioic acid, 2,2,13,13-Tetramethyl-tetradecane-1,6,9,14-tetraol, 6,10-Dihydroxy-2,2,14,14-tetramethyl-pentadecanedioic acid; treatment of Alzheimer's Disease, metabolic syndrome disorder, cancer, cardiovascular disease, diabetic nephropathy
10/28/2004US20040213442 Novel fatty acids analogous
10/27/2004EP1471049A1 Novel thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof
10/27/2004EP1470143A1 Compounds that inhibit factor xa activity
10/27/2004EP1470118A1 Alpha-methylenelactone synthesis in supercritical fluids
10/27/2004EP1470104A2 Novel compounds that inhibit factor xa activity
10/27/2004EP1469851A1 Melanocortin receptor agonists
10/27/2004EP0960108B1 Matrix metalloproteinase inhibitors
10/27/2004CN1541096A Compounds which mimic chemical and biological properties of discodermolide
10/27/2004CN1539825A Compounds useful to treat retroviral infections
10/26/2004US6809223 Process for stereoselective synthesis of prostacyclin derivatives
10/26/2004US6809207 Amino acid derivatives
10/21/2004WO2004089926A2 Genipin derivatives and uses thereof
10/21/2004WO2004089868A1 Amorphous simvastatin calcium and methods for the preparation thereof
10/21/2004US20040209925 e.g., phenyl ((1S,2R)-1-(3,5-difluorobenzyl)-3-{[(1S)-7-ethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-2-hydroxypropyl)carbamate; inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide
10/21/2004US20040209914 Aromatic sulfone hydroxamic acids and their use as protease inhibitors
10/21/2004US20040209847 treating and preventing a variety of diseases and conditions such as aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic retinopathy, dyslipidemia, dyslipoproteinemia, hypertension, impotence, insulin resistance, peroxisome proliferator activated receptor associated disorders
10/21/2004CA2521095A1 Amorphous simvastatin calcium and methods for the preparation thereof
10/20/2004EP1467726A2 A method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same
10/20/2004CN1538964A Substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors
10/20/2004CN1171866C Aryloxyarylsulfonylamino hydroxamic acid derivatives
10/19/2004US6806264 Arylphenyl-substituted cyclic ketoenols
10/14/2004WO2004087852A1 PERFUME COMPOSITIONS AND 3,6-DICYCLOPENTYL-δ-VALERO- LACTONE
10/14/2004WO2004071401A3 Hydroxamic acid derivatives as histone deacetylase inhibitors (hdca)
10/14/2004US20040204596 preventing or treating degradation of collagen, degradation of collagen by bacterial collagenases during a bacterial infection, regeneration of skin and ligaments, tumoral invasion and degenerative diseases having fibrinoid degeneration of collagen
10/14/2004US20040204594 S-(+)-4-Methoxy-6-phenethyl-5,6-dihydro-pyran-2-one; plant extracts for nutraceutical foods, topical ointments
10/14/2004US20040204502 Such as 4-(4-(3-hydroxy-3-methyl-butane-1-sulfinylmethyl)-phenylmethanesulfinyl)-2 -methyl-butan1-ol for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders
10/14/2004US20040203119 synthase (PKS) system, comprising at least two modules, of said PKS, wherein said PKS has been modified to prevent its utilization of its native starter unit, but wherein said PKS is able to incorporate a diketide substrate into a polyketide that is at least a triketide
10/13/2004EP1466899A1 Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient
10/13/2004EP1466898A1 Beta-amyloid protein production/secretion inhibitors
10/13/2004EP1466886A2 New salts of HMG-CoA reductase inhibitors
10/13/2004EP1466590A1 Cosmetic use of new desquamative agents
10/13/2004EP1277750B1 Hydrates and crystals of a neuraminic acid compound
10/13/2004EP0848712B1 Dihydropyran derivatives as viral neuraminidase inhibitors
10/13/2004CN1535956A Substituted phenyl keto-enol pesticide and weedicide
10/07/2004WO2004085427A1 Enantioselective hydrogenation of intermediates during tipranavir synthesis
10/07/2004WO2004085344A2 Production of oxy-michael adducts
10/07/2004US20040198814 prevention , therapy of cardiovascular disorders, dyslipidemias, glucose metabolism, hypoglycemic agents; reduce fat concentration in meat; reduce cholesterol concentration in eggs
10/07/2004DE10313118A1 Enantioselektive Hydrierung von Intermediaten bei der Tipranavir-Synthese Enantioselective hydrogenation of intermediates in the synthesis of tipranavir
10/07/2004CA2520129A1 Enantioselective hydrogenation of intermediates in the synthesis of tipranavir
10/06/2004EP1463820A1 Method of screening compounds
10/06/2004EP1463723A1 Process for the preparation of simvastatin
10/06/2004EP1101755B1 Anthranilic acid derivatives
10/06/2004CN1535145A Methyl analogs of simvastatin as novel HMG-CoA reductase inhibitors
10/05/2004US6800646 Sulfamato hydroxamic acid metalloprotease inhibitor
10/05/2004US6800612 Have vasodilating activity and inhibit the aggregation of the platelets; releasing no
09/2004
09/30/2004WO2004082682A1 Amino cyclobutylamide modulators of chemokine receptor activity
09/30/2004WO2004052831A3 Method for the production of optically active dihydropyrones
09/30/2004US20040192771 Cerdiovascular disorders; antilipemic agents; alzheimer's disease; anticancer agents; sepsis; thrombosis; hypotensive agents; kidney diseases; antiinflammatory agents
09/30/2004US20040192687 Dna-pk inhibitors
09/30/2004CA2519220A1 Amino cyclobutylamide modulators of chemokine receptor activity
09/29/2004EP0993439B1 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as mek inhibitors
09/28/2004US6797831 Process for lactonization to produce simvastatin
09/28/2004US6797721 Contacting the cancer cell with a phorboxazole derivative to inhibit growth of cancer cells, induction of apoptosis and inhibition of metastises
09/28/2004CA2224125C Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride
09/23/2004WO2004080990A1 C-glycoside derivatives and salts thereof
09/23/2004WO2004080962A1 2,4,6-phenyl substituted cyclic ketoenols
09/23/2004WO2004080377A2 Kcnq channel modulating compounds and their pharmaceutical use
09/23/2004WO2004050613A3 2-substituted-3-propenamide derivatives and methods of using the same
09/23/2004WO2004043884A3 Novel acylating reagents
09/23/2004WO2004030684A3 Kavalactone product
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