Patents
Patents for C07D 265 - Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms (11,132)
03/2008
03/05/2008EP1893560A2 3-methanesulfonylquinolines as gaba-b enhancers
03/05/2008EP1732541A4 Cyclic compounds
03/05/2008CN101137290A Use of 4-aminopyrimidines for the prevention of fungal pests novel 4-aminopyrimidines method for production thereof and agents comprising the same
03/05/2008CN100372841C Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity
03/04/2008US7339057 Reacting methanesulfonyl chloride with 3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid, reacting with 2-amino-3-methyl-5-chlorobenzoic acid to produce -[3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-8-methyl-4H-3,1-benzoxazin-4-one
03/04/2008US7338952 N-[2-[4-[(4-chlorophenyl)ethynyl]-2-methylphenoxy]-1-methylethyl]-1,4-benzenedimethanamine; phosphorylation, polymorphonuclear leukocyte, macrophage, lipopolysaccharide, tumor necrosis factor- alpha, cytokine IFN- gamma, interleukin-2 mediated disorders ; arthritis, osteoarthritis, Alzheimer's disease
02/2008
02/28/2008WO2008023004A1 Single enantiomer beta agonists method for production and use thereof as a medicament
02/28/2008US20080051393 Novel cannabinoids and methods of use
02/28/2008US20080050296 using an aminoalcohol derived from 4-amino-2-butanol, which have a higher CO2 absorption capacity; global warming; e.g. 4-(diethylamino)-2-butanol or 4-(piperidino)-2-butanol
02/28/2008CA2661143A1 Enantiomerically pure beta agonists, manufacturing and use thereof
02/27/2008EP1711479B1 Process for the production of dtpa-bis anhydride
02/27/2008EP1248612B1 Novel compounds and compositions as protease inhibitors
02/27/2008CN101133040A Novel heterocyclic oxime derivatives, method for preparing same and use thereof as hypoglycaemic or hypolipidemic agents
02/27/2008CN101133039A New enantiomerically pure beta agonists, process for the manufacture thereof, and use thereof as medicaments
02/27/2008CN101132796A Pharmaceutical composition containing phenoxazinium compound as active ingredient
02/21/2008US20080045533 Novel cyclohexyl sulphones
02/21/2008US20080045470 Ceramides and Apoptosis-Signaling Ligand
02/20/2008EP1889845A1 Novel pleuromutilin derivatives
02/20/2008EP1175411B1 Cyclothiocarbamate derivatives as progesterone receptor modulators
02/20/2008CN101128444A New pharmaceutically-active compounds for the treatment of respiratory diseases
02/20/2008CN101125834A Method for synthesizing anti-AIDS pharmaceutical efavirenz
02/19/2008US7332511 Vanilloid receptor ligands and their use in treatments
02/19/2008US7332500 Heterocyclic antiviral compounds
02/19/2008US7332105 Stabilizer mixture comprising specific compounds of the 2,4-bis-(4-phenylphenyl)-6-(2-hydroxyphenyl)-1,3,5-triazine class and selected other UV absorbers as protectants against damage by light, heat and oxygen
02/19/2008CA2210072C Crop protection products
02/14/2008WO2008005954A3 Tryphostin-analogs for the treatment of cell proliferative diseases
02/14/2008WO2007117560A8 Piperidine and morpholine renin inhibitors
02/14/2008US20080039662 Isomerizing an alkyl cis-4-(alkylsulfonylamino)cyclohexanecarboxylate to form the trans isomer with a base (alkali metal lower alkoxide, hydride or amide) in an aprotic solvent (toluene); forming the free acid by hydrolysis; sulfonation of alkyl 4-aminocyclohexanecarboxylate with alkylsulfinyl chloride
02/14/2008US20080039453 Enantiomerically pure R-etifoxine, pharmaceutical compositions thereof and methods of their use
02/14/2008US20080039442 Compounds With Kv4 Ion Channel Activity
02/14/2008US20080038840 Fluorescent Method And Compounds To Monitor Protein-Lipid Binding
02/14/2008US20080038331 Enantiomerically pure S-etifoxine, pharmaceutical compositions thereof and methods of their use
02/12/2008US7329754 modulators of the monoamine receptors, in particular the serotonin, dopamine and norepinephrine receptors, and the biogenic amine transporters for serotonin, dopamine and norepinephrine;
02/12/2008CA2220140C (2-morpholinylmethyl)benzamide derivatives
02/07/2008WO2006105304A8 Phenyl and pyridyl lta4h modulators
02/07/2008US20080032983 Ortho-Substituted N'-Benzylidene-(3-Hydroxyphenyl)Acethydrazides
02/07/2008US20080032982 2-{2-[3-(4-chlorophenyl)acryloyl]-4-methylphenoxy}-4-phenylbutanoic acid; Peroxisome Proliferator Activated Receptors (PPAR); diabetes, dyslipidemia and/or atherosclerosis
02/07/2008US20080032981 Aryl n-cyanoguanidines and methods related thereto
02/07/2008US20080032960 PI3 kinase antagonists
02/06/2008EP1883418A2 Sclerostin and the inhibition of wnt signaling and bone formation
02/06/2008EP1883402A2 Hydroxybenzamide derivatives and their use as inhibitors of hsp90
02/06/2008CN101119964A 9-经取代四环素 9- substituted tetracycline
02/06/2008CN101117335A Morpholine derivatives for use as dopamine agonists in the treatment of i.a. sexual dysfunction
02/06/2008CN100366615C Reactive materials for limited play optical devices and methods of making same
02/05/2008US7326789 E.g., 2-(4-Chloro-phenylsufonylamino)-4,5-dimethoxy-N-(4-(thiomorpholine-4-sulfonyl)-phenyl)-benzamide; cardiovascular disorders; hypotensive agents; angina pectoris, cardiac insufficiency, thrombolytic agents; atherosclerosis; activating soluble guanylate cyclase to adjust a disturbed cyclic GMP balance
02/05/2008US7326704 Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests
02/05/2008US7326702 antibiotics, fungicides, viricides; treating microbial infections; fused rings based on 1,4-benzoxazino(2,3,4-ij)quinolin-4-one for example
02/05/2008CA2289206C Efficient enantioselective addition reaction using an organozinc reagent
01/2008
01/31/2008WO2008012385A1 Phytotoxic halogenated derivatives of benzoxazinones
01/31/2008US20080027211 Enantiopure Heterocyclic Compound Useful for the Preparation of Peptides Which Can Be Potentially Used as Medicaments
01/31/2008US20080027038 N-Acylated lipophilic amino acid derivatives
01/31/2008US20080026943 Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives
01/30/2008CN101115717A Substituted bis aryl and heteroaryl compounds as selective 5ht2a antagonists
01/29/2008US7323466 Morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity
01/29/2008US7323462 Sexual disorders; anxiolytic agents; psychological disorders; analgesics; neurodegenerative disorders ; obsessive complusive disorders; antidepressants; headaches; schizophrenia; eating and sleep disorders
01/24/2008WO2008010897A2 Process for making 3-substituted 2-amino-5-halobenzamides
01/24/2008US20080021126 Alpha-aminoketones derivatives with one or 2 hydroxyalkylaminobenzoyl groups, e.g., 2-benzyl-1-[4-(2-hydroxyethylamino)phenyl]-2-dimethylamino-1-butanone; reduced VOC emission before curing and migration and/or extraction of residual photoinitiator from cured product; high initiator efficiency; inks
01/24/2008US20080021024 Metalloprotease inhibitors
01/24/2008US20080021023 Morpholinyl and pyrrolidinyl analogs
01/24/2008CA2656357A1 Process for making 3-substituted 2-amino-5-halobenzamides
01/23/2008EP1567498B1 Mandelic acid derivatives
01/23/2008CN101111487A Processes for producing 4-aminoquinazolines
01/23/2008CN101110478A Electrode for fuel cell and fuel cell employing the electrode
01/23/2008CN101108860A Beta-enol imine structure boron fluoride complex and method of synthesizing the same
01/22/2008US7320997 Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
01/17/2008WO2008007780A1 Pentadienamide derivative
01/17/2008CA2658097A1 Pentadienamide derivatives
01/16/2008EP1562918B1 Substituted benzoxazinones and uses thereof
01/16/2008CN101107235A Morpholines as 5HT2C agonists
01/16/2008CN101104598A Process for preparing trans-4-amino-1-cyclohexanecarboxilic acid derivatives
01/15/2008US7319111 Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists
01/10/2008WO2008005954A2 Tryphostin-analogs for the treatment of cell proliferative diseases
01/10/2008WO2007050425A3 Lxr modulators
01/10/2008US20080009488 protein kinase inhibitors such as Methyl {5-[2-(5-chloro-2-methylphenyl)-1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl]-1H-benzimidazol-2-yl}carbamate, used to modulate cellular activities such as proliferation, differentiation, apoptosis, migration and chemoinvasion
01/09/2008EP1874743A2 Purified form of tanaproget
01/09/2008EP1732887B1 1-(1h-indol-1-yl)-3-(4-methylpiperazin-1-yl)-1-phenyl propan-2-ol derivatives and related compounds as modulators of the norepinephrine (ne) and the serotonine (5-ht) activity and the monoamine reuptake for the treatment of vasomotor symptoms (vms)
01/09/2008EP1625117B1 Novel phenoxazinone derivatives as enzyme substrates and use thereof as indictor in the detection of microorganisms with peptidase activity
01/09/2008EP1487809B1 Process for the preparation of morpholine derivatives and intermediates therefore
01/09/2008EP0850227B1 Pyridazin-3-one derivatives, their use, and intermediates for their production
01/08/2008US7317008 Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
01/03/2008US20080004441 Iminization and complexing product of a phenylthioalkylamine (e.g., p-isopropylphenylthioethylamine), a monophenylimine of a 1,2-aryldione (.e.g., diisopropylphenyl)imino]acenaphthylen-1(2H)-one, and a metal salt (e.g., FeCl2); oligomerization of ethylene
01/03/2008US20080004273 Inhibitors of VEGF and HGF receptor signaling; treating cell proliferative diseases; N-(4-(6,7-Dimethoxyquinolin-4-yloxy)-3-fluorophenyl)-2-oxo-1-phenylpyrrolidine-3-carboxamide
01/03/2008US20080004270 3,4-Disubstituted Pyrazoles as Cyclin Dependent Kinases (Cdk) or Aurora Kinase or Glycogen Synthase 3 (Gsk-3) Inhibitors
01/03/2008US20080004267 Human protein tyrosine phosphatase inhibitors and methods of use
01/03/2008US20080004262 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period
01/02/2008EP1871379A2 Cyanoarylamines
01/02/2008CN101098846A Hydroxyphenol derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic uses thereof
01/02/2008CN100358595C Safety shield system for prefilled syringe
01/01/2008US7314950 Sulfinating a trans-alkyl 4-aminocyclohexanecarboxylate (formed by iminating the cis-analog with a benzaldehyde and hydrolyzing the product) with an alkanesulfinyl chloride and oxidizing the product to form an alkyl 4-alkylsulfonamidocyclohexanecarboxylate, which then may be hydrolyzed
01/01/2008US7314932 Methods for minimizing thioamide impurities
01/01/2008US7314875 Tricyclic aromatic and bis-phenyl sulfinyl derivatives
01/01/2008US7314872 Selective in presence of at least one other cathepsin isozyme; such as morpholine-4-carboxylic acid {2-cyclopentyl-1--[2-(4-methoxy-phenylamino)-1--methyl-ethylcarbamoyl]-ethyl}-amide
12/2007
12/27/2007WO2007148775A1 Chain amine compound
12/27/2007WO2007117559A8 Renin inhibitors
12/27/2007US20070299074 Guanidine Compounds, and Use Thereof as Binding partners for 5-Ht5 Receptors
12/27/2007US20070299072 Kv1.5 potassium channel inhibitors
12/26/2007EP1868605A2 Phenyl and pyridyl lta4h modulators
12/26/2007CN100357281C Bicyclic compounds, process for their preparation and pharmaceutical composition containing them
12/25/2007US7312330 Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
12/25/2007US7312209 An immunosuppressants for treating allograft rejection, transplant rejection, psoriasis, and rheumatoid arthritis, a 9,10-dihydro-9-oxo-acridine-3-yl- derivatives
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