Patents
Patents for C07D 257 - Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms (9,612)
05/2008
05/01/2008US20080103312 processes for the synthesis of 5-phenyl-1-trityl-1H-tetrazole, an intermediate useful in the synthesis of irbesartan.
05/01/2008US20080099111 Water-based synthesis of poly(tetrazoles)
04/2008
04/30/2008EP1511739B1 Polymorphs of valsartan
04/29/2008US7365085 2-(3-{3-[[2-chloro-3-(trifluoromethyl)benzyl](2,2-dephenylethyl)amino]propoxy}phenyl)-ethanol; agonists of the nuclear receptors, LXR alpha and LXR beta used to increase ABCA1, ABCG1, and apolipoprotein E expression and inhibiting cholesterol absorption
04/29/2008CA2343204C Arylsulfonanilide ureas
04/29/2008CA2297732C Heterocyclic vinylethers against neurological disorders
04/29/2008CA2254833C Pharmaceutical for treatment of neurological and neuropsychiatric disorders
04/24/2008WO2008046463A1 Metal chelates having a perfluorinated peg group, method for the production thereof, and use thereof
04/24/2008WO2007132005A3 Hybrid compounds based on polyol(s) and at least one other molecular entity, polymer or otherwise, especially of the polyorganosiloxane type, method for the preparation thereof, and applications of the same
04/24/2008US20080096945 Amorphous and Crystalline Forms of Losartan Potassium and Process For Their Preparation
04/24/2008US20080096930 1-(2-hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-phenyl)-ethanone; 6-(3-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio)isonicotinic acid; 1-(2-hydroxy-4-{3-[4-(2H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-3-trifluoromethyl-phenyl)-ethanone; treatment of migriane
04/24/2008US20080096892 C-Kit Modulators And Methods Of Use
04/24/2008US20080096869 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors
04/24/2008US20080096848 Substituted N-Aryl-9-Oxo-9H-Fluorene-1-Carboxamides and Analogs as Activators of Caspases and Inducers of Apoptosis
04/24/2008CA2666910A1 Metal chelates having a perfluorinated peg radical, processes for their preparation, and their use
04/23/2008EP1914225A1 Salt molten at room temperature and display device
04/23/2008EP1912956A1 Metal salts of 2 ' - ( 1h-tetraz0l-5-yl) -1 . 1 ' -biphenyl-4-carboxaldehyde
04/23/2008CN101165062A Novel synthesis of irbesartan
04/23/2008CN101165048A Method for preparing polyisocyanic acid ester
04/23/2008CN100383116C Methoximinophenylacetic acid amides
04/22/2008US7361770 Valsartan benzyl ester is hydrolyzed with an excess alkali metal hydroxide; washed with an organic solvent; acidified and isolated
04/22/2008US7361672 Pyrazoles, triazoles, or tetrazoles substituted with an aryl- or heteroarylcarbonylamino group and an aminocarbonylmethyl group: 5-chloro-thiophene-2-carboxylic acid (1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-1H-[1,2,4]triazol-3-yl)-amide; improved selectivity towards thrombin
04/17/2008WO2008027385A3 Processes for the synthesis of 5-phenyl -1 trityl-1h-tetrazole
04/17/2008US20080091010 Induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; antiviral and antitumor agents
04/17/2008US20080090996 Thrombopoietin mimetics
04/17/2008US20080090885 Combining water, potassium permanganate, and polar inert organic solvent to form first reaction mixture, filtering, adding losartan to form second reaction mixture, adding formaldehyde to second reaction mixture to form precipitate,filtering, acidifying to form precipitate of losartan 5-carboxylic acid
04/17/2008US20080090787 Thrombopoietin mimetics
04/17/2008US20080087549 Comprising a nitrogen-containing biphenyl derivative; can fill through holes or via holes at a micron or sub-micron level even in a case where it consists of one component; can be prepared and handled extremely easily and can stably fill the through holes or via holes for a long time
04/16/2008EP1911350A1 Amidine compound and herbicide
04/16/2008EP1910251A1 Method for isolating 5-substituted tetrazoles
04/15/2008CA2411468C Thrombopoietin mimetics
04/10/2008WO2008021804A3 Therapeutic amides and related compounds
04/10/2008WO2008004110A3 Process for the preparation of the angiotensin ii antagonist valsartan
04/10/2008US20080085894 Alpha-(n-sulfonamido)acetamide derivatives as beta-amyloid inhibitors
04/10/2008US20080085891 Asthma and allergic inflammation modulators
04/09/2008EP1906952A1 Mao-b inhibitors useful for treating obesity
04/09/2008CN101160292A Synthesis of cyclen derivatives
04/09/2008CN101160126A Angiotensin ii receptor antagonists
04/09/2008CN101160125A Niacin receptor agonists, compositions containing such compounds and methods of treatment
04/09/2008CN101157660A Dibenz tetraaza [14] annulene compound and preparation method and application thereof
04/09/2008CN100379415C Hetero biaryl derivatives as matrix metalloproteinase inhibitors
04/08/2008CA2232663C At1-receptor antagonists for preventing and treating postischemic renal failure and for protecting ischemic kidneys
04/03/2008US20080081812 and inverse agonist; 2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazole; obesity and obesity-related metabolic disorders
04/02/2008EP1904464A1 1-cycloalkyl-5-iodotetrazoles
04/02/2008EP1904463A2 Complexes containing perfluoroalkyl, method for the production and use thereof
04/02/2008EP1904462A2 Complexes containing perfluoroalkyl, method for the production and use thereof
04/02/2008EP1904439A2 Sphingosine kinase inhibitors
04/02/2008CN101153027A Process for the manufacture of valsartan
04/02/2008CN100378102C Process for preparation of phthalocyanin compound and intermediate and these intermediate compound
04/01/2008US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
04/01/2008US7351725 For therapy of immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection
04/01/2008US7351389 Aminocarboxylate ligands having substituted aromatic amide moieties
03/2008
03/26/2008EP1901731A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment
03/25/2008US7348333 Treating bone disorder caused by osteoclasts, tumor growth and tumor metastasis, prophylaxis of cardiovascular disorders, nephropathies or retinopathies
03/20/2008WO2007144512A3 Diazeniumdiolate derivatives, method for the preparation thereof, pharmaceutical compositions thereof, and use of same in the fields of hypertension and cardiovascular pathologies
03/20/2008US20080071091 Processes and compounds for the preparation of substituted naphthylindole derivatives
03/20/2008US20080070869 Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators
03/19/2008CN101146763A Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
03/19/2008CN101143853A Biphenyltetrazoles compounds and preparation method thereof
03/18/2008US7345095 Alpha, beta -peptide inhibitors; Alzheimer's disease; 2-(4-Chloro-benzenesulfonylamino)-3-phenyl-propionic acid methyl ester
03/18/2008US7345072 As precursors for angiotensin II antagonists; deprotecting the reactive tetrazole nitrogen an anhydrous or concentrated aqueous solution of a hydrohalic acid to obtain the active antagonist
03/18/2008US7345071 Process for the synthesis of Losartan potassium
03/13/2008WO2008030618A1 Benzo-fused compounds for use in treating metabolic disorders
03/13/2008WO2008028937A1 N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions
03/13/2008WO2007130890A3 Cyclopentane-derivatives and their use as ocular hypotensive agents
03/13/2008WO2007106546A3 Metal complexes of tetraazamacrocycle derivatives
03/13/2008US20080064732 Substituted 4-hetarylpyrazolines
03/13/2008CA2662091A1 N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions
03/12/2008EP1896491A2 Monoazole ligand platinum analogs
03/12/2008EP1896433A2 Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl)-n-pentanoyl-n-[2'-(1h-tetrazol-5-yl)bi-phenyl-4-ylmethyl]-amine
03/12/2008EP1896394A1 Substituted enaminones as nicotinic acetylcholine receptor modulators
03/12/2008CN100374425C Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers
03/11/2008CA2421880C Resorcinol derivatives
03/06/2008WO2008027385A2 Processes for the synthesis of 5-phenyl -1 trityl-1h-tetrazole
03/06/2008WO2008026937A1 Method of dynamic nuclear polarisation (dnp) and compounds and compositions for use in the method
03/06/2008US20080058387 Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds
03/06/2008US20080058382 Polyamine compounds
03/06/2008US20080058334 Dermatological or oncological disorders; N-(4-fluorophenyl)-N'-[4-[1-(1H-imidazol-1-yl)-2-methylpropyl]phenyl]urea for example
03/05/2008EP1893597A2 Ampa receptor potentiators
03/05/2008EP1893582A2 Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders
03/05/2008CN101137616A Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
03/05/2008CN100372853C Metal porphyrin nanotube and nanoline and their preparation process
03/05/2008CN100372852C Synthesis of temozolomide and analogs
03/04/2008US7339052 5-benzylmercaptotetrazole in acetonitrile and N-alkyimidazole is used to prepare internucleoside linkages; efficient and rapid
02/2008
02/28/2008US20080050795 Mixture Of At Least Two Different Antibodies Specific For Predetermined Antigens And Use Of The Mixture
02/28/2008DE10066210B4 Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques Use of perfluoroalkyl-containing metal complexes as contrast agents in MR imaging for presentation of plaques
02/27/2008EP1891026A2 Cycloalkylidene compounds as selective estrogen receptor modulators
02/27/2008EP1891025A1 Method for the production of substituted azoles
02/27/2008EP1890694A1 Phenylalkyl substituted heteroaryl devivatives
02/27/2008CN101133035A Method for the production of losartan
02/27/2008CN101133010A Process and intermediate compounds useful in the preparation of statins
02/26/2008US7335773 induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; exhibit antiviral and antitumor properties
02/26/2008US7335768 using bis (phthalhydrazides) as glycoluril surrogates to control the size, shape and pattern of functional groups in curcubit forming reactions; form host-guest complexes
02/26/2008US7335649 3-{N'-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-2-hydroxy-3'-(tetrazol-5-yl)biphenyl for treatment of thrombocytopenia; colony stimulating factors
02/21/2008WO2008021804A2 Therapeutic amides and related compounds
02/21/2008WO2007103456A3 Piperazine and piperidine biaryl derivatives
02/21/2008US20080044827 Imaging of Enzyme Activity
02/21/2008US20080044457 Antitumor agents; time-release agents; pulverization
02/21/2008CA2660396A1 Therapeutic amides and related compounds
02/20/2008EP1889838A1 Thrombopoietin mimetics
1 ... 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 ... 97