Patents
Patents for C07D 253 - Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group (2,967)
10/2008
10/01/2008CN100422158C Inhibitors of Akt activity
09/2008
09/25/2008US20080234276 Heterocyclic Triazines as Hypoxic Selective Protein Kinase Inhibitors
09/24/2008EP1809615A4 Lamotrigine analogs
09/24/2008CN101273020A NNRT inhibitors
09/17/2008EP1970373A1 Alicyclic heterocyclic compound
09/17/2008EP1254122B1 Novel 3-substituted 1,2,4-benzotriazines, a method for their production and the use thereof
09/17/2008CN101265238A Method for synthesizing triazine ring derivatives
09/16/2008US7425629 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
09/16/2008US7425561 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
09/11/2008US20080221108 Anthranilic Acid Derivatives As Hm74A Receptor Agonists
08/2008
08/20/2008EP1957485A2 Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
08/20/2008CN100412064C Malononitrile compounds and its use
08/14/2008US20080194583 Tubulin Inhibitors
08/14/2008US20080194565 5-Phenyl-Pentanoic Acid Derivatives as Matrix Metalloproteinase Inhibitors for the Treatment of Asthma and Other Diseases
08/12/2008US7410968 N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-{4-[3-(1H-tetrazol-5-yl)propoxy]phenyl}butyl)guanidine hydrochloride; hydrates mucosal surfaces; are absorbed less rapidly, thus have a prolonged pharmacodynamic half-life; skin and respiratory disorders, vision deffects
08/05/2008US7407956 Benzamide inhibitors of the P2X7 receptor
07/2008
07/30/2008CN101230045A Aromatic triazin derivatives and uses thereof
07/23/2008EP1597242B1 Hiv inhibiting 1,2,4-triazines
07/17/2008WO2008056257A3 Novel triazinedione derivatives as gaba-b receptor modulators
07/17/2008US20080171741 e.g. 5-(4-Chlorophenyl)-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)furan-2-carboxamide; p38 alpha and beta kinase inhibitor; antiinflammatory agent; asthma, inflammatory bowel disease, osteoporosis, psoriasis, graft vs. host rejection, atherosclerosis, multiple myeloma, pain, myocardial ischemia
07/16/2008CN101219987A New nitrogen-containing heterocyclic derivative and organic electroluminescent element using the same
07/10/2008US20080167313 Antidiabetic agents; dyslipidemia; hhypoglycemic agents; atherosclerosis ; obesity; antiinflammatory agents; metabolism disorders
07/10/2008US20080167287 Imidazotriazines and imidazopyrimidines as kinase inhibitors
07/08/2008US7396850 Pyrazole derivative as PPAR modulator
07/02/2008EP1937651A1 Nnrt inhibitors
07/01/2008US7393667 Using oxidoreductase enzyme to convert ketones to chiral alcohols; precursors inhibitors of vascular endothelial growth factor receptor-2, useful as an anticancer agent
06/2008
06/24/2008US7390899 Process for the synthesis of high purity 3,5-diamino-6-(2,3-dichlorophenyl) (1,2,4-triazine)
06/24/2008US7390807 Crystal forms of lamotrigine and processes for their preparations
06/24/2008US7390806 Antibiotics containing borinic acid complexes and methods of use
06/18/2008EP1931460A2 Stabilization of organogels and hydrogels by azide-alkyneý2+3¨cycloaddition
06/18/2008EP1458692B1 A new and efficient process for the preparation of lamotrigine and related 3,5-diamino-6-substituted-1,2,4-triazines
06/12/2008WO2008070134A1 Inhibitors of akt activity
06/12/2008US20080139811 Reacting an amino, hydroxy substituted amide with a heterocyclic substituted carboxylic acid to produce (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl) amino-3-hydroxy-5-[2S-1-imidazolidin-2-onyl)-3-methyl-butanoyl] amino-1,6-diphenylhexane; inhibitors of HIV infection
06/12/2008US20080139808 Crystal forms of lamotrigine and processes for their preparations
06/12/2008US20080139565 Anthranilic Acid Derivatives and Their Use in Treatment of Diseases of Lipid Metabolism, in Particular Dyslipidaemia
06/12/2008US20080138283 1,2,4-triazole- 3,5-dione derivatives; for imaging and therapy of psychiatric, eating, sleeping, bipolar disorder; anxiolytic agent, antidepressant; Alzheimer's, Parkinson's diseases, epilepsy; imaging agents for a serotonin receptor
06/12/2008CA2670767A1 Inhibitors of akt activity
06/12/2008CA2659895A1 Improved method for synthesizing lamotrigine
06/05/2008US20080132706 Compounds as PDE IV and TNF Inhibitors
06/04/2008EP1204643B1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
05/2008
05/29/2008US20080125433 Method of treating hair loss using thyromimetic compounds
05/28/2008CN101189214A Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides
05/22/2008WO2008059259A2 Anticancer compounds with a benzo ( 1, 2, 4 ) triazin-3yl-amine core
05/15/2008US20080114169 Intermediates of active esters for peptide synthesis, labeling, analysis; purity
05/15/2008CA2668853A1 Novel triazinedione derivatives as gaba-b receptor modulators
05/13/2008US7371750 Compounds and compositions as protein kinase inhibitors
05/08/2008WO2007122638B1 An improved process for preparation of lamotrigine intermediates
05/08/2008DE102006049618A1 Triazine und Ihre Verwendung als Metalloproteinase-Inhibitoren Triazines and their use as metalloproteinase inhibitors
05/07/2008EP1328275B1 Substituted 4,5-dihydro-1,2,4-triazin-3-ones, 1,2,4-triazin-3-ones, and their use as fungicides and insecticides
05/06/2008US7368453 Quinazolinone compounds with reduced bioaccumulation
05/06/2008CA2244979C Proton conductor in liquid form
04/2008
04/30/2008CN100384423C Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
04/29/2008US7365068 Hepatitis C virus infections; -(3-cyclopropyl-4-(pentyloxy)phenyl)-3-nicotinoylthiourea;methyl 2-oxo-2-(5-((3-(4-(pentyloxy)-3-(trifluoromethyl)phenyl)thioureido)carbonyl)pyridin-2-ylamino)acetate
04/24/2008WO2008046657A1 Triazines and their use as inhibitors of metalloproteinases
04/24/2008US20080096891 Triazine derivatives, their preparation and therapeutic application thereof
04/23/2008EP1054875B1 Insecticidal dihydro-oxadiazines, -thiadiazines and -triazines
04/17/2008WO2008044688A1 Urea derivative
04/17/2008DE10234188B4 Oktupolare Moleküle als organische Halbleiter Octupolar molecules as organic semiconductors
04/02/2008CN101155790A 1,2,4-triazine derivatives, preparation and use thereof in human therapy
03/2008
03/27/2008US20080076921 Inhibitors of bruton's tyrosine kinase
03/26/2008EP1509218A4 Peptide deformylase inhibitors
03/19/2008EP1363630B1 Kappa opioid receptor ligands
03/13/2008WO2008030843A1 Heteroaromatic compounds having sphingosine-1-phosphate (s1p) receptor agonist and/or antagonist biological activity
03/13/2008WO2008030838A2 Heteroaromatic compounds having sphingosine-1-phosphate (s1p) receptor agonist biological activity
03/13/2008WO2007122638A3 An improved process for preparation of lamotrigine intermediates
03/13/2008US20080064872 Heteroaromatic compounds having sphingosine-1-phosphate (s1p) receptor agonist biological activity
03/13/2008CA2662852A1 Heteroaromatic compounds having sphingosine-1-phosphate (s1p) receptor agonist and/or antagonist biological activity
03/13/2008CA2662850A1 Heteroaromatic compounds having sphingosine-1-phosphate (s1p) receptor agonist biological activity
03/12/2008CN100374425C Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers
03/06/2008US20080058337 Pyrrolotriazine kinase inhibitors
02/2008
02/21/2008WO2008019798A1 A process for the preparation of lamotrigine
02/21/2008US20080045536 Fused heterocyclic compounds useful as kinase modulators
02/21/2008CA2659290A1 A process for the preparation of lamotrigine
02/12/2008US7329757 Chloroazinium compounds: 2-chloro-5-methyl-1-(3-trifluoromethyl-phenyl)-pyridinium chloride; intermediates for preparting iminoazine herbicides: N-cyclopropyl-5-methyl-1-(3-trifluoromethylphenyl)-2(1H)-pyridineimine
02/07/2008WO2008015429A2 Pharmaceutical compounds
02/05/2008CA2339272C Nitrogen-containing heterocyclic carboxamide derivatives or salts thereof and antiviral agents comprising the same
01/2008
01/31/2008US20080027037 Cyclic compounds
01/30/2008EP1881966A2 Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-trianzin-6-ones, and their use as fungicides
01/24/2008US20080020985 Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof
01/24/2008DE102006032107A1 Neue aromatische Aza-Heterocyclen, Herstellungsverfahren dazu und Verwendung des Materials in der organischen Elektronik New aromatic aza-heterocycles, manufacturing method thereof and use of the material in organic electronics
01/17/2008WO2008006738A1 Novel aromatic aza heterocycles, method of production and use of the material in organic electronics
01/17/2008US20080015195 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase
01/10/2008WO2008003141A1 Therapeutic compounds
01/10/2008US20080009620 Tricyclic Spacer Systems For Nonlinear Optical Devices
01/10/2008CA2656851A1 Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity
01/09/2008EP1874761A2 4h-1,2,4-triazin-5-one derivatives, their preparation and their use as alpha 7 nicotinic acetylcholine receptors
01/01/2008US7314876 Administering to mammals nitrogen compounds, as mitogen activated kinase inhibitors, for prophylaxis asthma, respiratory system disorders, graft versus host disease, atherosclerosis and arthritis
12/2007
12/27/2007US20070299075 e.g. 1-[4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-pyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-4-(aminosulfonyl)aminobutan-2-ol; inhibit the tyrosine kinase activity of endothelial and fibroblast growth factors receptors; angiogenesis inhibitor; anticarcinogenic agent
12/26/2007CN101094838A Tubulin binding anticancer agents and prodrugs thereof
12/19/2007EP1866292A1 Tricyclic 1,2,4-triazine oxides and compositions therefrom for therapeutic use in cancer treatments
12/19/2007EP1664031B1 Adamantane and azabicyclo-octane and nonane derivatives process of their preparation and their use as dpp-iv inhibitors
12/12/2007CN101087755A Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
12/11/2007US7307169 Isotopically enriched N-substituted piperazines and methods for the preparation thereof
12/06/2007WO2007138075A1 Method for preparing lamotrigine and its intermediate 2,3-dichlorobenzoyl chloride
12/06/2007US20070281939 5-(3,5-Dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-N-(1-hydroxy-cycloheptylmethyl)benzamide derivatives in which the triazine ring has various 4-substituents, e.g., carbamoylmethyl-, dimethylaminoethyl-, acetylaminoethyl-, and pyridinylmethyl-; treating rheumatoid arthritis
12/05/2007CN100352819C Novel compounds as NS3-serine protease inhibitors of hepatitis c virus
12/04/2007US7304063 Inhibitors of Akt activity
11/2007
11/29/2007CA2650611A1 Compositions and methods for fgf receptor kinases inhibitors
11/27/2007US7301021 Substituted imidazole compounds
11/22/2007US20070270416 Active Compound Combinations Having Insecticidal and Acaricidal Properties
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