Patents
Patents for C07D 245 - Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms (898)
03/2015
03/03/2015US8969333 Therapeutic compositions and methods
02/2015
02/17/2015US8957203 Hepatitis C virus inhibitors
01/2015
01/27/2015US8940722 Compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune disease
01/20/2015US8937080 Pyrimidine substituted macrocyclic HCV inhibitors
01/06/2015US8927569 Macrocyclic compounds as antiviral agents
12/2014
12/31/2014CN103012292B 二苯并[b,f][1,2]二氮芳辛的合成方法 Dibenzo [b, f] [1,2] Synthesis of diazocine
12/31/2014CN102924390B 1,5-二氮杂环辛烷-1-甲酸叔丁酯的合成方法 1,5-diazabicyclo octane-1-carboxylic acid tert-butyl ester synthesis method
11/2014
11/06/2014US20140329805 Dual small molecule inhibitors of cancer and angiogenesis
09/2014
09/25/2014US20140288059 Therapeutic compositions and methods
08/2014
08/26/2014US8815927 Bivalent diazo bicyclic Smac mimetics and the uses thereof
08/19/2014US8809264 Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors
08/06/2014CN102584725B 一种制备二氮杂环辛四烯的方法 A diazepine cyclooctatetraene method of preparing
07/2014
07/31/2014US20140213627 Naphthoquinone derivatives useful for prevention of amyloid deposits and treatment of diseases involving amyloidogenesis
07/03/2014US20140187526 Pharmaceutical compositions for the treatment of conditions responsive to proteasome inhibition
07/02/2014CN101478970B 喹喔啉基大环丙型肝炎病毒丝氨酸蛋白酶抑制剂 Quinoxalinyl macrocyclic serine protease inhibitors of hepatitis C virus
07/01/2014US8765728 [1,5]-diazocin derivatives
06/2014
06/10/2014US8748388 Antitumoral compounds
05/2014
05/30/2014WO2014081886A1 Macrocyclic broad spectrum antibiotics
05/20/2014US8729060 Macrocyclic polyoxazole compounds and use thereof
05/14/2014CN103797009A Z-选择性闭环复分解反应 Z- selective ring closing metathesis reaction of
05/13/2014US8722881 Method of synthesis of tetradentate amide macrocycle ligand and its metal-complex
04/2014
04/23/2014EP2721027A2 Z-selective ring-closing metathesis reactions
04/15/2014US8697680 Naphthoquinone derivatives useful for prevention of amyloid deposits and treatment of diseases involving amyloidogenesis
04/03/2014WO2014048692A1 Low catalyst loading in metathesis reactions
04/03/2014US20140093450 Pretargeting kit for imaging or therapy comprising a trans-cyclooctene dienophile and a diene
03/2014
03/26/2014EP2711351A1 Low catalyst loading in metathesis reactions
03/04/2014US8664212 Diazo bicyclic Smac mimetics and the uses thereof
02/2014
02/27/2014WO2014008204A3 Structures of proteasome inhibitors and methods for synthesizing and use thereof
02/13/2014WO2013188750A3 Substituted macrocyclic compounds having proteasome inhibitory activity
02/13/2014WO2013181584A3 Modulation of hepatitis b virus cccdna transcription
02/04/2014US8642610 Dual small molecule inhibitors of cancer and angiogenesis
02/04/2014US8642014 Luminescent compounds
01/2014
01/08/2014CN103502224A Flumazenil complexes, compositions comprising same and uses thereof
01/01/2014EP2678320A1 Flumazenil complexes, compositions comprising same and uses thereof
12/2013
12/24/2013CA2617096C Macrocyclic inhibitors of hepatitis c virus
12/19/2013WO2013188750A2 Substituted macrocyclic compounds having proteasome inhibitory activity
12/10/2013CA2552317C Hcv ns-3 serine protease inhibitors
12/05/2013CA2874828A1 Modulation of hepatitis b virus cccdna transcription
11/2013
11/26/2013US8592403 Diazepine and diazocane compounds as MC4 agonists
11/06/2013CN103382185A Separation method of chiral isomers of 6, 12-dibenzyl dibenzo[b, f][1, 5]dinitrogen heterocyclooctatetraene and determination method of chiral isomer configuration
10/2013
10/15/2013US8557798 Macrocyclic heterocyclic aspartyl protease inhibitors
10/08/2013US8551982 Benzodioxane inhibitors of leukotriene production
10/02/2013EP2643300A1 Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases
09/2013
09/25/2013CN103319423A Method for synthesizing 3,7-diaryl-1,5-dioxo-3,7-diazacyclooctane
08/2013
08/27/2013US8518928 Therapeutic compounds
08/21/2013EP2627641A1 Reversal of drug-induced neuromuscular block using novel molecular containers
08/13/2013US8507640 Methods of ring opening polymerization and catalysts therefor
04/2013
04/25/2013US20130102774 Thionation process and a thionating agent
04/24/2013CN103058939A Heterocyclic compound and organic light-emitting device containing the same
04/18/2013US20130092903 Heterocyclic compound and organic light-emitting device containing the same
04/16/2013US8420626 Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof
04/03/2013CN103012292A Synthetic method of dibenzanthracene [b,f][1,2] diazocine
03/2013
03/27/2013CN101233117B Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy
03/14/2013US20130065872 Synthesis of syrbactin proteasome inhibitors
03/13/2013CN101228169B Macrocyclic inhibitors of hepatitis c virus
03/07/2013US20130060001 Catalysts for the preparation of carbonates from epoxides and co2
03/05/2013US8389560 HCV protease inhibitors
02/2013
02/13/2013CN102924390A Synthetic method of 1,5-diazacyclooctane-1-tert-butyl ester formate
01/2013
01/16/2013CN102875777A Novel epoxy hardener and preparation method thereof
01/09/2013EP2542537A1 Novel compounds for modulation of orphan nuclear receptor rar-related orphan receptor-gamma (ror gamma, nr1f3) activity and for the treatment of chronic inflammatory and autoimmune disease
12/2012
12/20/2012US20120323000 Z-selective ring-closing metathesis reactions
12/06/2012WO2012167171A2 Z-selective ring-closing metathesis reactions
12/05/2012CN102812011A [1,5]-diazocin Derivatives
11/2012
11/28/2012CN102803337A New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units
11/06/2012US8304385 Macrocyclic tetrazolyl hepatitis C serine protease inhibitors
10/2012
10/30/2012US8298512 Methods of determining β-III tubulin expression
10/18/2012US20120264802 Photosensitizers for targeted photodynamic therapy
10/10/2012EP2507219A2 Synthesis of syrbactin proteasome inhibitors
10/02/2012US8278322 HCV NS3 protease inhibitors
10/02/2012US8278293 Diazo bicyclic Smac mimetics and the uses thereof
09/2012
09/26/2012EP2501685A1 [1,5]-diazocin derivatives
09/26/2012CN1914225B HCV NS-3 serine protease inhibitors
09/25/2012US8273875 High performance luminescent compounds
09/11/2012CA2445159C Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
09/06/2012US20120225892 [1,5]-Diazocin Derivatives
08/2012
08/30/2012WO2012114342A1 Flumazenil complexes, compositions comprising same and uses thereof
08/21/2012CA2552319C Hcv ns-3 serine protease inhibitors
08/16/2012US20120207703 Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating hcv infections
08/09/2012US20120202800 Dual small molecule inhibitors of cancer and angiogenesis
07/2012
07/19/2012WO2012070015A9 Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases
07/18/2012CN102584725A Method for preparing dinitrogen heterocyclooctatetraene
07/17/2012US8222257 Phosphono-pent-2-en-1-yl nucleosides and analogs
07/17/2012US8222239 quaternary ammonium compounds, conjugated to polymers, used as microbiocides
07/11/2012CN101282978B Macrocylic inhibitors of hepatitis c virus
06/2012
06/12/2012CA2560897C Macrocyclic compounds as inhibitors of viral replication
06/05/2012US8193174 Responsive luminescent lanthanide complexes
05/2012
05/31/2012WO2012070015A1 Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases
05/16/2012EP1904460B1 Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy
05/16/2012CN1854128B Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
05/15/2012US8178545 Dual small molecule inhibitors of cancer and angiogenesis
05/15/2012US8178520 Macrocyclic compounds as antiviral agents
05/03/2012US20120108562 Therapeutic compositions and methods
05/03/2012US20120108499 Peptoid compounds
04/2012
04/25/2012EP1482933B1 Potent, simplified derivatives of immunosuppressive agents
04/19/2012WO2012051413A1 Reversal of drug-induced neuromuscular block using novel molecular containers
04/10/2012US8153784 Imaging of enzyme activity
03/2012
03/13/2012US8134146 Heterocyclic radical or diradical, the dimers, oligomers, polymers, dispiro compounds and polycycles thereof, the use thereof, organic semiconductive material and electronic or optoelectronic component
02/2012
02/29/2012EP2423201A1 Luminescent macrocyclic lanthanide complexes
02/23/2012US20120046437 Methods of ring opening polymerization and catalysts therefor
02/09/2012US20120035159 Substituted isoquinoline derivative
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