Patents
Patents for C07D 241 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings (18,673)
01/2008
01/08/2008US7317028 Antitumor agents; autoimmune disease; skin disorders; anticancer agents
01/08/2008US7317013 such as N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-[1-(2-hydroxyethyl)piperidin-4-yl]butyl} guanidine dihydrochloride and optionally with g-coupled receptor agonist or bronchodilators, used for promoting hydration of mucosal surfaces; improved pharmacokinetics
01/08/2008CA2394027C New derivatives of octahydro-2h-pyrido[1,2-a] pyrazine, their preparation process and pharmaceutical compositions that contain them
01/03/2008WO2008002820A2 Substituted benzyl amine compounds
01/03/2008WO2008002817A1 Butyl and butynyl benzyl amine compounds
01/03/2008WO2008002583A1 Glycine transporter-1 inhibitors
01/03/2008WO2007117961A3 Renin inhibitors
01/03/2008US20080004331 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition
01/03/2008US20080004290 Anti-Cancer Agents
01/03/2008US20080004289 Glycine transporter-1 inhibitors
01/03/2008US20080004265 HIV Integrase Inhibitors
01/03/2008US20080004262 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period
01/03/2008US20080004248 prostate cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, androgenic alopecia, precocious puberty, adrenal hyperlasia and polycystic ovarian syndrome, breast cancer, endometriosis, leiomyoma and precocious puberty, estrogen dependent diseases
01/03/2008CA2656089A1 Substituted benzyl amine compounds
01/03/2008CA2656075A1 Butyl and butynyl benzyl amine compounds
01/03/2008CA2655159A1 Glycine transporter-1 inhibitors
01/02/2008EP1871749A1 1h-quinaz0line-2,4-diones and their use as ampa-receptor ligands
01/02/2008EP1871739A1 Compounds which inhibit beta-secretase activity and methods of use thereof
01/02/2008EP1871374A2 2,3 substituted pyrazine sulfonamides as inhibitors of crth2
01/02/2008EP1656361B1 Piperazine with or-substituted phenyl group and their use as glyt1 inhibitors
01/02/2008CN101096593A Organometallic compounds and emission-shifting organic electrophosphorescence
01/02/2008CN101096592A Organometallic compounds and emission-shifting organic electrophosphorescence
01/01/2008USRE39991 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
01/01/2008US7314937 Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
01/01/2008US7314888 2-{5-[(2,4-diisobutoxyphenyl)(hydroxy)methyl]-2-isobutoxyphenyl}-acetic acid; inhibits the activity of transcription factor AP-1
12/2007
12/27/2007WO2007149479A1 Pyrazine derivatives and uses thereof in renal monitoring
12/27/2007WO2007149478A2 Pyrazine derivatives with extended conjugation and uses thereof
12/27/2007WO2007149448A2 Pyrazinones as cellular proliferation inhibitors
12/27/2007WO2007148774A1 Cyclic amine compound
12/27/2007WO2007148711A1 N-(3,4-disubstituted phenyl)salicylamide derivative
12/27/2007WO2007147746A1 2-pyrazinecarboxamide derivatives
12/27/2007WO2007147217A1 Method of treatment of glioma brain tumour
12/27/2007WO2004058735A3 Ligands of melanocortin receptors and compositions and methods related thereto
12/27/2007US20070299263 Hydroxy Alkyl Amines
12/27/2007US20070299080 Benzamide derivatives and uses related thereto
12/27/2007US20070299077 Aryl-substituted polycyclic amines, method for the production thereof, and use thereof as a medicament
12/27/2007US20070299072 Kv1.5 potassium channel inhibitors
12/27/2007US20070299064 Pesticidal Heterocyclic Dihaloallyl Compounds
12/27/2007CA2656825A1 Method of treatment and agents useful for same
12/27/2007CA2655857A1 Pyrazine derivatives with extended conjugation and uses thereof
12/27/2007CA2654781A1 2-pyrazinecarboxamide derivatives
12/27/2007CA2652859A1 Pyrazinones as cellular proliferation inhibitors
12/27/2007CA2628661A1 Pyrazine derivatives and uses thereof in renal monitoring
12/26/2007EP1870396A1 Benzyloxypropylamine derivative
12/26/2007EP1869059A1 Organometallic complex, and light-emitting element, light-emitting device and electronic device using the organometallic complex
12/26/2007EP1868986A1 Tetrahydronaphthalene derivatives method for the production and the use thereof in the form of antiphlogistics
12/26/2007EP1868605A2 Phenyl and pyridyl lta4h modulators
12/26/2007CN101094841A Indinavir derivatives useful in immunoassay
12/26/2007CN101092402A New compound in sulfonyl ureas, and medicine use
12/26/2007CN101092401A Stereoselective alkylation of chiral 2-methyl-4-protected piperazines
12/26/2007CN100357276C Quinoline and quinoxaline compounds as PDGF-R and/or LCD tyrosine kinase inhibitors
12/26/2007CN100357275C N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases
12/25/2007US7312333 N-heterocyclic hydroxyethylamine compounds; human immunodeficiency virus (HIV) protease
12/25/2007US7312246 Inhibiting interaction of alpha-helical protein with another protein or binding site; inhibiting cellular invasion of HIV
12/25/2007US7312218 For use as anticoagulant agents for therapy of thromboembolic disorders; 6-chloro-naphthalene-2-sulfonic acid [1-(1-cyclopentyl-piperidin-4-yl)-2-oxo-pyrrolidin-3-yl]-amide; )-2-methyl-benzothiazole-6-sulfonic acid [1-(1-isopropyl-piperidin-4-yl)-2-oxo-pyrrolidin-3-yl]-amide
12/21/2007WO2007146870A1 Cyclic substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity
12/21/2007WO2007146553A2 N-[2-[[(diaminomethylene)amino]oxy]ethyl]-3-[(2,2-difluoro-2-phenylethyl)amino]-6-methyl-2-oxo-1(2h)-pyrazineacetamide
12/21/2007WO2007146066A2 Novel piperazines, pharmaceutical compositions and methods of use thereof
12/21/2007WO2007144579A1 N-oxides of diarylurea derivatives and their use as chk1 inhibitors for the treatment of cancer
12/21/2007WO2007144409A1 Stereoselective synthesis of (s)-1-methyl-3-phenylpiperazine
12/21/2007CA2659512A1 Novel piperazines, pharmaceutical compositions and methods of use thereof
12/21/2007CA2653773A1 Cyclic substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity
12/21/2007CA2653039A1 Aryl- and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics
12/20/2007US20070293673 N-phenyl-2-pyrimidine-amine derivatives
12/20/2007US20070293672 N-phenyl-2-pyrimidine-amine derivatives
12/20/2007US20070293540 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition
12/20/2007US20070293509 treating eating disorders, obesity, type II diabetes, and substance abuse and/or addiction (including alcohol dependency and nicotine dependency); 6-(4-chloro-phenyl)-5-[methyl-(3-methyl-butyl)-amino]-pyrazine-2-carboxylic acid ((R)-2-cyclopropyl-2-hydroxy-propyl)-amide
12/20/2007US20070293504 N-phenyl-2-pyrimidine-amine derivatives
12/20/2007US20070293495 to treat Alzheimer's disease,Down syndrome and the other diseases associated with amyloid deposition; thiomethane, sulfinylmethane or sulfonylmethane compounds; 5-Chloro-4-[(4-chlorophenylsulfonyl)-(2,5-difluorophenyl)methyl]-2-(4'-hydroxypiperidin-1'-yl)pyridine
12/20/2007US20070293491 Indazole compounds and methods for inhibition of cdc7
12/20/2007US20070292933 Inhibitors of serine proteases, particular HCV NS3-NS4A protease
12/19/2007EP1866321A1 Organometallic complex, and light-emitting device and electronic appliance using the same
12/19/2007EP1664031B1 Adamantane and azabicyclo-octane and nonane derivatives process of their preparation and their use as dpp-iv inhibitors
12/19/2007EP1490062B1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
12/19/2007EP1032556B1 Pharmaceutically active compounds and methods of use
12/19/2007CN101090883A Substituted hydroxyethylamines
12/19/2007CN100355728C Inhibitors of dipeptidyl peptidase IV
12/18/2007US7309702 4-(3-Phenyl-3-carbocycloylpropyl)-1-phenyl- or pyridylpiperazine derivatives: 1-(2-methoxyphenyl)-4-[3-(benzoyl)-3-(phenyl)propyl]piperazine oxalate; serotonin receptor antagonists; Alzheimer's disease
12/13/2007US20070287697 Cgrp Receptor Antagonists
12/13/2007US20070286842 serine protease inhibitors, for the treatment of hepatitis c virus infections
12/12/2007EP1863774A2 Heterocyclical chromophore architectures with novel electronic acceptor systems
12/12/2007EP1863766A2 Certain substituted amides, method of making, and method of use thereof
12/12/2007EP1492794B1 Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
12/12/2007CN101087767A Fluorescent pyrazine derivatives and methods of using the same in assessing renal function
12/12/2007CN101087755A Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
12/12/2007CN101085760A Ligustrazine stilbenoids derivatives, preparation method thereof, medicament composition and use
12/12/2007CN100354271C Piperazine derivatives and process for the preparation thereof
12/12/2007CN100354267C Preventives or remedies for alzheimer's disease or amyloid protein fibrosis inhibitors containing nitrogen-containing heteroaryl compounds
12/11/2007US7307169 Isotopically enriched N-substituted piperazines and methods for the preparation thereof
12/11/2007US7307087 Antidepressants; analgesics; antiinflammatory agents; side effect reduction
12/11/2007CA2393271C Retroviral protease inhibiting compounds
12/06/2007WO2007139081A1 Anti-foot-and-mouth disease virus agent for animal belonging to family suidae or sheep, and method for prevention or treatment of foot-and-mouth disease in animal belonging to family suidae or sheep
12/06/2007WO2007139002A1 Method for producing nitrogen-containing fused ring compound
12/06/2007WO2007138998A1 Pharmaceutical composition comprising nitrogenated fused cyclic compound
12/06/2007WO2007138112A2 Compounds that interact with ion channels, in particular with ion channels from the kv family
12/06/2007WO2007072143A3 Chemical compounds
12/06/2007US20070282100 Boronic ester and acid compounds, synthesis and uses
12/06/2007CA2653933A1 Anti-foot-and-mouth disease virus agent for animal belonging to family suidae or sheep, and method for prevention or treatment of foot-and-mouth disease in animal belonging to family suidae or sheep
12/05/2007EP1862179A1 Novel use of sulfonamide compound in combination with angiogenesis inhibitor
12/05/2007EP1499319B1 Bicyclo 4.4.0 antiviral derivatives
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