Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
05/2014
05/14/2014CN102137841B 邻位取代卤代烷基磺酰苯胺衍生物及除草剂 Ortho-substituted aniline derivatives and halogenated alkylsulfonyl herbicides
05/08/2014US20140128598 Process for the synthesis of (2e)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
05/08/2014CA2831289A1 New process for the synthesis of (2e)-3(3,4-dimethoxyphenyl)prop-2-enenitrile and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
05/07/2014EP2727585A1 In-vivo screening method
05/07/2014EP2726462A1 Acetone solvate of ivabradine hydrochloride
05/07/2014CN103781767A 伊伐布雷定及其合成中间体的制备方法 Preparation ivabradine and synthetic intermediates
05/07/2014CN103772281A 伊伐布雷定的制备方法 Ivabradine preparation
05/07/2014CN103772120A 新颖的有机电致发光化合物和使用该化合物的有机电致发光设备 Novel organic electroluminescent compounds and the use of the compound organic electroluminescent devices
05/07/2014CN101768117B 一种盐酸伊伐布雷定晶型及其制备方法 One kind of hydrochloric acid in Iraq cutting cloth Lei Dingjing type and preparation method
05/06/2014US8716524 Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same
05/06/2014US8716278 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
05/06/2014US8716276 Thiophenyl and pyrrolyl azepines as serotonin 5-HT2C receptor ligands and uses thereof
05/06/2014US8716275 Compound for the treatment of hepatitis C
04/2014
04/30/2014CN103755636A Method for synthesizing Lorcaserin raceme derivative
04/30/2014CN103755635A Synthesis methods of lorcaserin derivative and salt thereof
04/29/2014US8710049 Diaminocyclohexane compounds and uses thereof
04/24/2014WO2014060575A2 Process for the enantioselective synthesis of a tetrahydrobenzazepine compound
04/24/2014WO2014060341A1 Substituted carbamate compounds and their use as transient receptor potential (trp) channel antagonists
04/17/2014WO2014057228A1 New method for synthesising -(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application to the synthesis of ivabradine and the addition salts of same with a pharmaceutically acceptable acid
04/17/2014US20140107334 Process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
04/17/2014US20140107323 SDP-containing Heterobifunctional Agents
04/16/2014EP2719689A1 Novel method for synthesising 3-(2-bromo-4,5-dimethoxyphenyl) propanenitrile and use for synthesising ivabradine and the added salts thereof with a pharmaceutically acceptable acid
04/16/2014CN103724266A Demethylivabradine salt as well as preparation method and application thereof
04/16/2014CN103724228A Novel method for synthesising 3-(2-bromo-4,5-dimethoxyphenyl) propanenitrile and use for synthesising ivabradine and the added salts thereof with a pharmaceutically acceptable acid
04/16/2014CN102633720B New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid
04/16/2014CN102603634B Process for the synthesis of ivabradine and its pharmaceutically acceptable acid addition salts
04/15/2014US8697910 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same
04/15/2014US8697686 Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-thtrahydro-1H-3-benzazepine hydrochloride
04/12/2014CA2829428A1 Novel synthesis process for 3-(2-bromo-4.5-dimethoxyphenyl)propanenitrile, and application to the synthesis of ivabradine and of its additon salts to a pharmaceutically acceptableacid
04/10/2014WO2014055548A1 Anti-fibrotic pyridinones
04/09/2014CN102911118B Benzo-azepine type derivative and preparation method and purpose thereof
04/09/2014CN102698803B Ruthenium complex catalyst and preparation method and application thereof
04/08/2014US8691809 Substituted benzoazepines as toll-like receptor modulators
04/08/2014US8691808 Antiviral compounds and their methods of use
04/03/2014WO2014049550A1 Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate
04/03/2014WO2014048692A1 Low catalyst loading in metathesis reactions
04/03/2014WO2014048165A1 Compound as potassium channel modulator
04/02/2014CN103702983A Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
04/02/2014CN103694174A Alpha-(N-benzyl)amino-epsilon-caprolactam compound as well as preparation method and application thereof
04/02/2014CN103694163A Compounds capable of being adopted as potassium channel modulators
04/02/2014CN102643232B Method for preparing caprolactam by beckmann rearrangement for cyclohexanone-oxime
04/02/2014CN102382052B Method for degrading and recovering epsilon-caprolactam of waste nylon 6 in ionic liquid/water mixed system
04/01/2014US8686134 Ionic liquids
03/2014
03/27/2014WO2014047370A1 Fluoroalkyl dibenzodiazepinone compounds
03/27/2014US20140088085 Substituted Benzoazepines As Toll-Like Receptor Modulators
03/26/2014EP2711351A1 Low catalyst loading in metathesis reactions
03/26/2014CN103664558A Process for separating methylcyclopentanone from cyclohexanone
03/26/2014CN102250004B Preparation method of 3-[(1-(1S)-phenylethyl) amino]-2,3,4,5-tetrahydro-2-oxo-1H-(3S)-benzazepine
03/26/2014CN102227404B Ammoximation process
03/26/2014CN101143843B Method for preparing epsilon-caprolactam
03/25/2014US8680267 Process for producing amide or lactam
03/25/2014US8680091 6-arylalkylamino-2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists
03/20/2014US20140081019 Process for the preparation of deuterated compounds containing n-alkyl groups
03/19/2014EP2707358A1 Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
03/19/2014CN203483884U Device for concentrating caprolactam solution with combination of mechanical vapor recompression and multiple-effect evaporation
03/19/2014CN103649054A Production of caprolactam from carbohydrate-containing materials
03/19/2014CN103648606A Mist separation device and reaction system
03/19/2014CN103641740A Method for preparing cyclohexane oxime and caprolactam by oxidizing cyclohexylamine through molecular oxygen in gas phase
03/19/2014CN102827080B Novel synthetic method of ivabradine and novel intermediate product of ivabradine
03/19/2014CN102161642B Method for synthesising ivabradine and its addition salts
03/18/2014US8673599 Preparation of 6-aminocaproic acid from 5-formylvaleric acid
03/13/2014US20140073632 Treating protein folding disorders with small molecule cftr correctors
03/12/2014CN102863382B Solvent recovery method of caprolactam rearrangement reaction products and application thereof
03/12/2014CN102329268B Preparation method for 7-chlorine-5-oxo-2,3,4,5-tetrahydro-1H-1-benzoazepine
03/11/2014US8669229 Benzazepine derivatives useful as vasopressin antagonists
03/06/2014US20140066432 Substituted Benzoazepines As Toll-Like Receptor Modulators
03/05/2014CN102093260B Stereospecific synthesis of piperidine derivative
02/2014
02/27/2014WO2014031226A1 The production of nitrogen compounds from a methane conversion process
02/27/2014WO2013017937A8 Process for the manufacture of ivabradine and of intermediates of synthesis thereof
02/27/2014US20140057900 Pro-Neurogenic Compounds
02/26/2014CN103601678A Synthetic method of 7-chloro-1,2,3,4-tetrahydrobenzo[b]azepine-5-one
02/26/2014CN103601645A Preparation method of 1-(phenethylamino) propane-2-alcoholic compounds or salts thereof
02/26/2014CN101659593B Organic electroluminescent compound and organic electroluminescent device using the same
02/25/2014US8658636 TRPV4 antagonists
02/20/2014US20140051684 Crystalline forms of (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride
02/19/2014EP2697202A1 Production of caprolactam from carbohydrate-containing materials
02/19/2014CN102399188B Novel method of Beckman transposition reaction
02/18/2014US8653065 Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
02/13/2014US20140045824 Method for producing complex crystal and method for screening complex crystal
02/12/2014CN103570601A Preparation method of optical active medicine intermediate
02/12/2014CN102532025B Preparation method for N-vinyl caprolactam capable of recycling raw materials
02/11/2014US8648067 Substituted phenoxypropylcycloamine derivatives as histamine-3 (H3) receptor ligands
02/06/2014WO2014021281A1 Partially saturated nitrogen-containing heterocyclic compound
02/06/2014WO2014020534A1 Ivabradine hydrochloride and the processes for preparation thereof
02/05/2014CN103562201A Substituted benzoazepines as TOLL-like receptor modulators
02/05/2014CN103562186A Substituted benzoazepines as toll-like receptor modulators
02/05/2014CN103562181A Method for producing hemiaminal compound and method for producing cyanoamine compound
02/05/2014CN103554024A Synthesis method for cationic bleaching activating agents with surface activity
02/05/2014CN103551086A Hydrogenation reaction device for refining caprolactam
02/05/2014CN102584703B Extraction method for removing trace impurities from caprolactam water solution
02/04/2014US8642587 Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
02/04/2014CA2767893C New method for the synthesis of ivabradine and the pharmaceutically acceptable acid addition salts thereof
02/04/2014CA2574002C Method for chiral inversion of (s)-(+)- and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and optically enriched mixtures thereof
01/2014
01/29/2014EP2189448B1 Processes for the Separation of 3-Benzazepine Racemates
01/29/2014CN103540625A Process for the enzymatic synthesis of (7s)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl) n-methyl methanamine, and application in the synthesis of ivabradine and salts thereof
01/29/2014CN103539738A Method and device for recovering caprolactam in benzene distillation residue
01/29/2014CN102015591B Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-choro-i-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
01/28/2014US8637664 Alkyl 4- [4- (5-oxo-2,3,5, 11a-tetrahydo-5H-pyrrolo [2, 1-c] [1,4] benzodiazepine-8-yloxy)-butyrylamino]-1H-pyrrole-2-carboxylate derivatives and related compounds for the treatment of a proliferative disease
01/23/2014WO2014013179A1 Method for the enzyme synthesis of (7s)-1-(3,4-dimethoxy bicyclo[4.2.0]octa-1,3,5-triene 7-yl) n-methyl methanamine, and application to the synthesis of ivabradine and the salts thereof
01/23/2014WO2014012401A1 Benzo-seven-member heterocyclic derivative and preparation method of benzo-seven-member heterocyclic derivative and medical application of benzo-seven-member heterocyclic derivative
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