Patents for C07B 49 - Grignard reactions (286)
06/2008
06/26/2008DE102006060949A1 Verfahren zur Herstellung von Menthylderivaten A process for preparing Menthylderivaten
06/17/2008US7387751 Method of preparing organomagnesium compounds
06/10/2008US7384580 higher reactivity with an electrophile; lithium chloride complexes; using organometallic R1(MgX).LiY, a fast exchange reaction occurs leading to Grignard reagents in high yields under mild conditions; ether solvent; phenyl-(4-cyanophenyl)methanol from benzaldehyde, 4-bromobenzonitrile and i-PrMgCl.LiCl
05/2008
05/22/2008WO2008033836A3 Process and intermediates for preparing integrase inhibitors
04/2008
04/24/2008WO2008047707A1 Method for producing biphenyl derivative
04/01/2008US7351847 Grignard processes with increased content of diphenylchlorosilanes
03/2008
03/20/2008WO2008033836A2 Process and intermediates for preparing integrase inhibitors
03/20/2008WO2008009378A3 Grignard reactions in microreactors
03/20/2008CA2661943A1 Process and intermediates for preparing integrase inhibitors
03/06/2008WO2008028166A1 Universal grignard metathesis polymerization
02/2008
02/28/2008WO2008023658A1 Process for isomerization of alkyl grignard reagents and process for production of organic compounds
02/20/2008EP1889849A1 Grignard reactions in microreactors
02/20/2008CN101125840A Grignard reagent synthesis reaction solvent in maltol production
02/20/2008CN101125797A Method for preparing 2,6-dimethyl-2-heptanol
01/2008
01/24/2008WO2008009378A2 Grignard reactions in microreactors
01/24/2008CA2655658A1 Method for grignard type reactions in microreactors
01/03/2008WO2007128601A3 Method for the preparation of a compound of the general formula r1-r1 and/or r1-r2 using homo and hetero coupling reactions
12/2007
12/19/2007CN101089011A Process of producing methyltestosterone with Grignard reagent as material
11/2007
11/15/2007WO2007128601A2 Method for the preparation of a compound of the general formula r1-r1 and/or r1-r2 using homo and hetero coupling reactions
10/2007
10/04/2007DE102006015378A1 Verfahren zur Synthese von Organoelementverbindungen A process for the synthesis of Organoelement
09/2007
09/19/2007CN100337997C Grignard preparation of unsaturated organic compounds
09/07/2007WO2007099173A1 Organomagnesium synthesis agent
09/06/2007DE102007010956A1 Magnesiumorganisches Synthesemittel Magnesium Organic synthesis means
09/06/2007DE102007010953A1 Magnesiumorganisches Synthesemittel Magnesium Organic synthesis means
08/2007
08/23/2007US20070194468 Method of preparing organomagnesium compounds
08/15/2007CN101016233A Synthetic method for 2,6-dimethy-5-heptenal
07/2007
07/26/2007WO2007082911A1 Preparation and use of magnesium amides
07/25/2007CN1328237C Process for the synthesis of peptides containing a 4-hydorxy-proline substructure
06/2007
06/28/2007DE102006049463A1 Preparation of synthetic agents containing diorganomagnesium compounds and their mixtures with alkali metal salts, useful in e.g. synthetic chemistry, comprises reacting an alkali metal with a Grignard compound and an organic halo compound
04/2007
04/26/2007DE102006049406A1 Preparation of synthetic agents containing diorganomagnesium compounds and their mixtures with alkali metal salts, useful in e.g. synthetic chemistry, comprises reacting an alkali metal with a Grignard compound and an organic halo compound
04/25/2007CN1312111C Process for preparing 2-[(dimethylamino)-methyl]-1-(3-methoxyphenyl)cyclohexanol
04/19/2007WO2007042578A1 Method for preparing diorganomagnesium-containing synthesis means
04/19/2007DE102006049462A1 Preparation of synthetic agents containing diorganomagnesium compounds and their mixtures with alkali metal salts, useful in e.g. synthetic chemistry, comprises reacting an alkali metal with a Grignard compound and an organic halo compound
03/2007
03/22/2007US20070066840 Contacting a phenyl Grignard reagent, an ether solvent, an aromatic halogenated coupling solvent, and a trichlorosilane; mole ratio of ether to Grignard reagent is 2-5, mole ratio of coupling solvent toGrignard reagent is 3-7, and mole ratio of trichlorosilane to Grignard reagent is 0.1-10.
03/22/2007US20070066826 Grignard processes with improved yields of diphenylchlorosilanes as products
03/08/2007WO2007026014A1 Solutions of anhydrous lanthanide salts and its preparation
03/07/2007EP1759765A1 Solutions of anhydrous lanthanide salts and its preparation
02/2007
02/21/2007EP1754709A1 Process for preparing vinylphosphates
01/2007
01/24/2007CN1902209A Grignard processes with increased content of diphenylchlorosilanes
01/24/2007CN1902208A Grignard processes with improved yields of diphenylchlorosilanes as products
10/2006
10/11/2006CN1844065A Selective alkylation reaction of acid anhydride or ester
10/04/2006EP1527043B1 Method for the production of 2- (dimethylamino)methyl|-1-(3-methoxyphenyl)cyclohexanol
09/2006
09/20/2006EP1701965A1 Grignard processes with increased content of diphenylchlorosilanes
09/20/2006EP1701964A1 Grignard processes with improved yields of diphenylchlorosilanes as products
08/2006
08/29/2006US7098344 Reaction of carbonyl compounds with organometallic reagents
01/2006
01/18/2006EP1246784B9 Reaction of carbonyl compounds with organometallic reagents
01/18/2006CN1723182A Process for the synthesis of peptides containing a 4-hydorxy-proline substructure
11/2005
11/08/2005US6962999 Using a nickel or palladium catalyzed coupling in which the catalyst has at least one phosphine or phosphite ligand
10/2005
10/19/2005EP1246784B1 Reaction of carbonyl compounds with organometallic reagents
10/06/2005US20050218532 higher reactivity with an electrophile; lithium chloride complexes; using organometallic R1(MgX).LiY, a fast exchange reaction occurs leading to Grignard reagents in high yields under mild conditions; ether solvent; phenyl-(4-cyanophenyl)methanol from benzaldehyde, 4-bromobenzonitrile and i-PrMgCl.LiCl
10/05/2005EP1582524A1 Method of preparing organomagnesium compounds
10/05/2005EP1582523A1 Method of preparing organomagnesium compounds
08/2005
08/18/2005CA2555453A1 Cross-coupling process for production of aromatic compounds from aliphatic organic compounds and aromatic organometallic reagents
08/17/2005CN1656049A Grignard preparation of unsaturated organic compounds
08/16/2005CA2197616C The preparation and use of (3-alkoxy-phenyl) magnesium chlorides
07/2005
07/28/2005WO2005068476A1 Grignard processes with increased content of diphenylchlorosilanes
07/28/2005WO2005068475A1 Grignard processes with improved yields of diphenylchlorosilanes as products
06/2005
06/23/2005US20050137382 A coordination catalyst comprising a complex of a metal center containing a ring, particularly a phenyl group, or a hydrocarbon group which links an amino group and a phosphine, amino, oxy, thio or arsinic group to stabilize the ligand structure; polymerization catalyst; Heck and Suzuki reactions
06/09/2005US20050124808 Using nickel or palladium coupling catalyst containing phosphine or phosphite ligands
05/2005
05/31/2005US6899830 Method for producing Grignard compounds
03/2005
03/29/2005US6872846 Process for preparation of tertiary alcohol esters
03/24/2005US20050065060 cleaning solvent for electronic parts, precision machinery components; extraction solvent
03/02/2005EP1509484A2 Process for preparing vinylaromatic compounds
12/2004
12/29/2004EP1490312A1 Grignard preparation of unsaturated organic compounds
11/2004
11/03/2004CN1543449A Solvents containing cycloalkyl alkyl ethers and process for production of the ethers
08/2004
08/19/2004DE4326169B4 Verfahren zur Herstellung von unsymmetrischen Bisarylverbindungen A process for the preparation of unsymmetrical Bisarylverbindungen
08/19/2004DE10304006B3 Continuous method for preparing Grignard adducts, on column of magnesium turnings through which a mixture of halide and cyclohexanone reactant is passed, optionally with direct hydrolysis and dehydration to cyclohexene derivative
04/2004
04/07/2004EP1405840A1 Solvents containing cycloalkyl alkyl ethers and process for production of the ethers
03/2004
03/18/2004WO2003102202A3 Process for preparing vinylaromatic compounds
01/2004
01/22/2004US20040015006 Efficient one pot process
01/02/2004EP1077923B1 An improved synthesis and purification of (r*,r*)-2- (dimethylamino) methyl]-1-( 3-methoxyphenyl) cyclohexanol hydrochloride
12/2003
12/11/2003WO2003102202A2 Process for preparing vinylaromatic compounds
12/11/2003CA2486803A1 Process for preparing vinylaromatic compounds
10/2003
10/16/2003WO2003084901A1 Grignard preparation of unsaturated organic compounds
09/2003
09/17/2003EP1344762A1 Process for preparation of tertiary alcohol esters
08/2003
08/21/2003US20030156998 Electrolytic cells; monitoring current; measurement impedance
08/20/2003EP1336431A2 A microreactor
08/19/2003US6608212 Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene
07/2003
07/01/2003US6586599 Catalyzed coupling reactions of aryl halides with silanes
05/2003
05/29/2003US20030100760 Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles
04/2003
04/22/2003US6552237 Grignard preparation of unsaturated organic compounds
01/2003
01/29/2003EP1279656A2 Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles
01/09/2003WO2003002500A1 Solvents containing cycloalkyl alkyl ethers and process for production of the ethers
01/02/2003US20030004357 Organometallic reagent and the carbonyl compound are provided and tempered separately in a suitable solvent before being pumped into a tempered mini/ micromixer
12/2002
12/11/2002EP1117668B1 Fluorous phosphines and process for their preparation
12/05/2002DE10220549A1 New Grignard, organomanganese, organozinc and organic halogen compounds are used in the preparation of decalin, diphenyl, diphenylethane and diphenylethene compounds, used in liquid crystal displays
10/2002
10/09/2002EP1246784A1 Reaction of carbonyl compounds with organometallic reagents
10/01/2002US6458978 Fluorous phosphines and process for their preparation
08/2002
08/21/2002CN1089331C Reaction of Grigrand compounds with carbonyl compounds and ensuring hydrolysis
08/13/2002US6432326 Method for the stereoselective production of grignard compounds and use thereof
07/2002
07/03/2002CN1356303A Process for preparing tetrahydronaphthalene derivative
06/2002
06/11/2002US6403802 Use of catalyst system comprising nickel, palladium, or platinum and imidazoline-2-ylidene or imidazolidine-2-ylidene in amination reactions
06/04/2002US6399829 Salt formation using hydrogen chloride in presence ot toluene; crystallization in nitrile solvent
05/2002
05/30/2002WO2002042252A1 Process for preparation of tertiary alcohol esters
05/16/2002DE10151710A1 Production of 2-substituted 1,2,3,4-tetrahydronaphthalen-2-ol compounds for use in liquid crystal mixtures, involves reacting the corresponding ketone with organometallic reagent in hydrocarbon-containing solvent
04/2002
04/09/2002US6369265 Heterocoupling reaction, mixing in a liquid an aryl halide, bonding to aromatic rings, grignard reaction, metal compound and heterocyclic carbene
03/2002
03/26/2002US6362357 Use a catalyst system comprising nickel palladium or platinum and imidazoline-2-ylidene or imidazolidine-2-ylidene in stille coupling reactions
02/2002
02/14/2002WO2001066248A3 C-c and c-n coupling catalyst comprising transition metal and carbene
11/2001
11/21/2001CN1075075C Preparation and use of (3-alkoxyphenyl) magnesium chlorides
11/13/2001US6316380 One transition metal compound and at least one n-heterocyclic carbene or its protonated salt
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