Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
09/2003
09/02/2003US6613760 Indole derivatives and their use as MCP-1 receptor antagonists
09/02/2003US6613757 Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy
09/02/2003US6613746 Cell adhesion proteins having cells with glycoprotein antibodies and carbohydrate determinants used to interfere with binding FC receptor and as complement inhibitors; antiinflammatory agents
09/02/2003US6613349 Bactericides
09/02/2003US6613328 Methods of treating thrombotic diseases with von Willebrand factor specific antibodies
09/02/2003US6613322 Administering enzyme inhibitors
08/2003
08/28/2003WO2003071268A2 Method for discovering pharmacologically active substances
08/28/2003WO2003070969A2 RNA INTERFERENCE MEDIATED INHIBITION OF BCL2 GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070965A2 The eaat2 promoter and uses thereof
08/28/2003WO2003070951A1 Arteriosclerosis-specific gene and utilization thereof
08/28/2003WO2003070897A2 RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR SUPERFAMILY GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070765A2 Growth hormone fusion protein
08/28/2003WO2003070751A2 Partial peptide mimetics and methods
08/28/2003WO2003070739A1 Partial and full agonists of a1 adenosine receptors
08/28/2003WO2003070738A2 Topiramate salts and compositions comprising and methods of making and using the same
08/28/2003WO2003070730A1 Pyrrolopyrimidine derivative
08/28/2003WO2003070727A1 Thiazolyl urea compounds for the treatment of cancer
08/28/2003WO2003070726A1 Pyranones useful as atm inhibitors
08/28/2003WO2003070717A1 Process for the manufacture of hmg-coa reductase inhibitory mevalonic acid derivatives
08/28/2003WO2003070716A1 Vitamin d3 derivatives and remedies using the same
08/28/2003WO2003070711A1 Oxa- and thiadiazoles and their use as metalloproteinase inhibitors
08/28/2003WO2003070709A1 Novel phenylalanine derivative
08/28/2003WO2003070707A1 Fused pyridazine derivative compounds and drugs containing the compounds as the active ingredient
08/28/2003WO2003070706A1 Tricyclic pyrazole derivatives for the treatment of inflammation
08/28/2003WO2003070701A2 Syntheses of quinazolinones
08/28/2003WO2003070692A1 Novel propionic acid derivative
08/28/2003WO2003070675A2 Substituted 10-aryl-11h-benzo[b]fluorenes and 7-aryl-5,6-dihydro-benzo[a]anthracenes for selective effects on estrogen receptors
08/28/2003WO2003070275A1 Use of an inhibitor or antagonist against tissue factor
08/28/2003WO2003070263A1 Process for producing hydrophobic glycyrrhiza extract with high qualities
08/28/2003WO2003070261A1 Pharmacological substance from the plant tribulus terrestris
08/28/2003WO2003070245A1 Mono-ester and asymmetrically substituted di-ester pro-drugs of the dopamine d1 receptor agonists
08/28/2003WO2003070236A2 Tricyclic pyrazole derivatives, process for their preparation and their use as antitumor agents
08/28/2003WO2003070235A1 Medicinal compositions for inhibiting tryptase
08/28/2003WO2003070220A1 Ph-sensitive cationic lipids, and liposomes and nanocapsules containing the same
08/28/2003WO2003070197A2 RNA INTERFERENCE MEDIATED INHIBITION OF TGF-BETA AND TGF-BETA RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
08/28/2003WO2003070188A2 Method of treating trx mediated diseases
08/28/2003WO2003070184A2 Sodium channel blockers
08/28/2003WO2003070166A2 Novel tyloindicines and related processes, pharmaceutical compositions and methods
08/28/2003WO2003055911A3 Cystine-knot fold protein
08/28/2003WO2003049698A3 Substituted hydrazones as inhibitors of cyclooxygenase-2
08/28/2003WO2003045315A3 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses
08/28/2003WO2003037384A3 Polymer conjugates of protein kinase c inhibitors
08/28/2003WO2003031447A3 Pyrimidine derivatives
08/28/2003WO2003028756A3 An in vivo animal model of chronic arterial occlusion and use of collagenase to facilitate guide wire crossing in chronic arterial occlusions
08/28/2003WO2003027116A3 Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)one derivatives
08/28/2003WO2003020202A3 Method for reducing hypertension and heart failure
08/28/2003WO2003013434A3 Methods and compositions for treating diseases associated with excesses in ace
08/28/2003WO2003002559A3 Piperidine compounds for use as orexin receptor antagonist
08/28/2003WO2003002058A3 Bone anabolic compounds and methods of use
08/28/2003WO2002102990A3 Fibroblast growth factor and nucleic acid encoding same
08/28/2003WO2002097044A3 Alternative splice forms of proteins as basis for multiple therapeutic modalities
08/28/2003WO2002094192A3 Antibodies against tumor necrosis factor delta (april)
08/28/2003WO2002081508A3 Use of cd25 binding molecules in steroid-resistant patients
08/28/2003WO2002074337A8 Hmgb1 protein inhibitors and/or antagonists for the treatment of vascular diseases
08/28/2003WO2002046749A3 Screening method for identifying compounds that selectively induce interferon alpha
08/28/2003WO2002041880A3 Use of pyrazolo[4,3-d]pyrimidines
08/28/2003WO2002040032A3 Cytoprotective estrogen derivatives
08/28/2003WO2002040005A3 Blockade of sodium channels by phenol derivatives
08/28/2003WO2002034940A3 Methods for screening compounds that modulate lipid metabolism
08/28/2003WO2002015885A3 Oral fast-melt formulation of a cyclooxygenase-2 inhibitor
08/28/2003WO2002012470A3 A member of the lysyl oxidase gene family
08/28/2003WO2002012326A3 Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the von hippel-lindau tumor suppressor protein
08/28/2003WO2002008399A3 Human kinases
08/28/2003WO2002000638A8 Substituted phthalides as anti-convulsive drugs
08/28/2003WO2001095859A3 Novel heterocyclic analogs of diphenylethylene compounds
08/28/2003WO2001085147A3 STABILIZED FORMULATIONS OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL) ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL) BENZO[b]THIOPHENE AND SALTS THEREOF
08/28/2003US20030163845 Elongase genes and uses thereof
08/28/2003US20030163834 Erk-5 deficient animals and methods of inhibiting angiogenesis through the inhibition of Erk-5
08/28/2003US20030162991 Crystallizing impurity-contaminated N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine from a mixed solvent of alcohol and water to remove a contaminating impurity into a mother liquor and produce crystals
08/28/2003US20030162969 Process and intermediates for pyridazinone antidiabetic agents
08/28/2003US20030162968 1,4-Disubstituted benzo-fused urea compounds
08/28/2003US20030162967 Having antithrombotic effect; fortherapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses; reversible inhibitors of blood clotting enzymes factor Xa and/or factor VIIa
08/28/2003US20030162964 Benzene-fused heterocycle derivatives and drugs containing the same as the active ingredient
08/28/2003US20030162826 Degradation fragments
08/28/2003US20030162814 Amines such as 2-(3-(N-hydroxyamidino)phenylamino)-N-(2'-sulfamoylbiphenyl-4-yl)-2 -methylpropionamide, used as anticoagulants or for prophylaxis of arteriosclerosis, angina pectoris, restinosis or metastasis
08/28/2003US20030162813 Heterocyclic nitrogen comppounds such as 4-(5-methyl-3-phenyl-isoxazol-1-yl)benzenesulfonamide, used as non-steroidal antiinflammatory agents or antiarthritic agents; cyclooxygenase inhibitors
08/28/2003US20030162811 Heterocyclic amines such as 4-(3'-Thienyl)-alpha, alpha, 1-trimethyl-4-piperidinemethanol and/or prodrugs, used as analgesics for prophylaxis of neuropathic pain
08/28/2003US20030162808 Acetindine derivatives, their preparation and medicaments containing them
08/28/2003US20030162807 Compositions and methods for treating osteoporosis and lowering cholesterol
08/28/2003US20030162804 Tertiary amines such as N-allyloxyethyl-1,2,3,4,5,6-hexahydro -6,11,11-trimethyl-2,6- methano-3-benzazocin-10-ol and salts, administered as sodium channel modulators for prophylaxis of arrhythmias, spasms or epilepsy
08/28/2003US20030162802 Preferential enzyme inhibitors such as 2-((4-6-pyrimidinedion -2-yl)amino)-4-methyl-5-thiazolecarboxylic acid ethyl ester, used for prophylaxis of lymphocyte associated disorders
08/28/2003US20030162798 Pyrrolo[3,4-d]pyrimidinone derivatives and their use as medicaments
08/28/2003US20030162794 Benzazole derivatives and their use as jnk modulators
08/28/2003US20030162793 Methods for preventing or treating cardiac arrhythmia
08/28/2003US20030162787 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
08/28/2003US20030162786 Use of cysteine derivatives for the preparation of a medicament intended to treat pathologies which result from the formation of the heterotrimeric G protein
08/28/2003US20030162784 Pyridazinone aldose reductase inhibitors
08/28/2003US20030162779 4-oxo-4H-thiazole derivative for treating or preventing neurodegenerative disorders
08/28/2003US20030162777 Administering a biheterocyclic compounds containing aminocarbonyl, aminothiocarbonyl or aminosulfonyl group for treating neuromuscular dysfunction of the lower urinary tract in a mammal in need of such treatment
08/28/2003US20030162776 Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
08/28/2003US20030162775 Heterocyclic substituted pyrazolones
08/28/2003US20030162774 Derivatives of sulfonylurea, sulfonylthiourea, sulfonylguanidine, thioacylsufonamide and acylsulfonamide; useful for treating thromobis
08/28/2003US20030162767 Novel 1,3-dihydro-2h-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them
08/28/2003US20030162765 Use in treatment and prevention of central nervous system and other disorders
08/28/2003US20030162764 Pyrimidine A2b selective antagonist compounds, their synthesis and use
08/28/2003US20030162759 Preventing or treating cardiovascular disease including atherosclerosis
08/28/2003US20030162737 Preventives and remedies for pulmonary hypertension
08/28/2003US20030162709 Methods of generating multispecific, multivalent agents from VH and VL domains
08/28/2003US20030162701 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them
08/28/2003US20030162252 Isolating cDNAs encoding novel G protein-coupled receptor proteins derived from human spleen