Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
03/2004
03/02/2004US6699854 2-substituted 4-heteroaryl- pyrimidines, inhibitors of cyclin-dependent kinases (cdks)
03/02/2004US6699846 Such as ischemia and reperfusion injury, using specified glycolipids structurally related to monophosphoryl lipid a but with reduced proinflammatory and pyrogenic activity
03/02/2004US6699840 Controlled- or delayed-release forms of topiramate
03/02/2004US6699832 May contain another compound to treat diabetes, sexual dysfunction, atherosclerosis, insulin resistance, impaired glucose tolerance, hypercholesterolemia or hypertriglyceridemia
03/02/2004US6699681 Identifying compounds that upregulate eces; regulating a beta catabolism in a cell and decreasing the amount of a beta in a cell; diagnosing and treating alzheimer's disease; mutant ece nucleic acids and mutant ece polypeptides.
03/02/2004US6699672 Heparanase specific molecular probes and their use research and medical applications
02/2004
02/26/2004WO2004016769A2 Antibodies directed to monocyte chemo-attractant protein-1 (mcp-1) and uses thereof
02/26/2004WO2004016764A2 eNOS MUTANTS USEFUL FOR GENE THERAPY
02/26/2004WO2004016761A2 Gene therapy for critical limb ischemia with wild type or mutant enos
02/26/2004WO2004016613A2 Purine derivatives and their use as antiproliferative agents
02/26/2004WO2004016612A2 New purine derivatives
02/26/2004WO2004016608A1 Novel quinuclidine derivatives and their use
02/26/2004WO2004016606A1 Pyrazole inhibitors of the transforming growth factor
02/26/2004WO2004016605A1 2-aminopyrimidine derivatives as adenosine a1 and a2a receptor antagonists
02/26/2004WO2004016593A1 Diaryl compounds as monoamine reuptake inhibitors
02/26/2004WO2004016551A1 Method for the preparation of a silicic acid comprising extrudate, said extrudate, its use and a pharmaceutical composition comprising the said extrudate
02/26/2004WO2004016272A1 Use of reboxetine for the treatment of hot flashes
02/26/2004WO2004016264A1 Thrombopoetin receptor activator and process for producing the same
02/26/2004WO2004004763A3 Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair
02/26/2004WO2004000369A3 Method of magnetically manipulating a cell with magnetisable particles
02/26/2004WO2003106505A9 Process for the manufacture of n-acyl-(epi)k5-amine-o-sulfate-derivatives and products thus obtained
02/26/2004WO2003103575A3 Compounds, compositions, and methods
02/26/2004WO2003101374A3 Use of new etonogestrel esters
02/26/2004WO2003099337A3 Inclusion complexes of rosiglitazone
02/26/2004WO2003090684A3 Polymer compositions containing a macrocyclic triene compound
02/26/2004WO2003087333A3 Modulation of stem and progenitor cell differentiation, assays, and uses thereof
02/26/2004WO2003074008A3 Aminoalkylphosphonates and related compounds as edg receptor agonists
02/26/2004WO2003072024A3 Methods of treating vascular disease
02/26/2004WO2003066813A3 MINRs AS MODIFIERS OF INSULIN RECEPTOR SIGNALING AND METHODS OF USE
02/26/2004WO2003064443A3 New corticosteroids
02/26/2004WO2003060085A3 Mammalian neural stem cells, compositions and uses thereof
02/26/2004WO2003057829A3 Methods of generating multispecific, multivalent agents from vh and vl domains
02/26/2004WO2003057144A3 Change inhibitors of dipeptidyl peptidase iv
02/26/2004WO2003050261A3 (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial f1f0 atp hydrolase
02/26/2004WO2003047517A3 Novel-n-[4-(1h-imidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1-h-pyrazole-5-carboxamides as factor xa
02/26/2004WO2003040144A3 Heterocyclic compound based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds
02/26/2004WO2003038058A3 Surfactant protein d for the prevention and diagnosis of pulmonary emphysema
02/26/2004WO2003026568A3 Androstanes as androgen receptor modulators
02/26/2004WO2003018516A3 Glucagon-like peptide-1 analogs
02/26/2004WO2003013493A8 Histone deacetylase enzyme-inhibiting derivatives of hydroxamic acid as new cytokine synthesis-inhibiting anti-inflammatory drugs
02/26/2004WO2003011899A3 Antigenic polypeptides
02/26/2004WO2003011892A3 Glp-1 exendin-4 peptide analogs and uses thereof
02/26/2004WO2002103014A3 Antisense oligonucleotides which can inhibit the formation of capillary tubes by endothelial cells
02/26/2004WO2002098869A3 1,4-disubstituted benzo-fused cycloalkyl urea compounds
02/26/2004WO2002094322A3 Combination medicament for treatment of neoplastic diseases containing cyanoguanidine ikk inhibitors and a second anti-neoplastic drug
02/26/2004WO2002087419A3 Biological pacemaker
02/26/2004WO2002072636A8 Crystals of whole antibodies and fragments thereof and methods for making and using them
02/26/2004WO2002062204A3 Methods for diagnosing and treating heart disease
02/26/2004WO2002057211A8 Symmetrically disubstituted aromatic compounds and pharmaceutical compositions for inhibiting poly (adp-ribose) glycohydrolase, and methods for their use
02/26/2004WO2002055067A3 Fumaric acid derivatives as nf-kappab inhibitors
02/26/2004WO2002046418A3 Lipid-associated molecules
02/26/2004WO2002041910A8 Methods and compositions for the treatment of diseases of the eye
02/26/2004WO2002033089A3 Ixodes scapularis tissue factor pathway inhibitor
02/26/2004WO2002022112A3 Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
02/26/2004WO2001074299A3 Compositions and methods for inhibition of cancer invasion and angiogenesis
02/26/2004WO2001057175A3 Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
02/26/2004US20040040049 Reduction in the formation of the complex in the presence of the candidate agent as compared with in the absence of candidate agent indicates the candidate agent inhibits the binding of LBP-2 to the LBP-2 binding molecule
02/26/2004US20040039298 Noninvasive measurement of chemical substances
02/26/2004US20040039297 Noninvasive measurement of chemical substances
02/26/2004US20040039204 Compositions of n-(methylethaylaminocarbonyl)-4-(-3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosacccharides
02/26/2004US20040039200 1,2,3,4,10,10a-hexahydropyrazino(1,2-a)indole derivatives useful for treating disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders, and diabetes
02/26/2004US20040039199 4-((3-(7-(3,3-dimethyl-2-oxobutyl)-9-oxa-3,7-diazabicyclo(3.3. 1)non-3-yl)propyl))amino)benzonitrile, benzenesulfonic acid salt, is useful in the prophylaxix
02/26/2004US20040039198 Administering to a mammal an aromatic and heteroacromatic substituted imidazole compound to treat diseases: renal disease, wound healing, ucler, ocular disorder, diabetic nephropathy, atherosclerosis, fibrosis, ALzheimer's disease
02/26/2004US20040039196 (2-Oxindol-3-ylidenyl) acetic acid derivatives and their use as protein kinase inhibitors
02/26/2004US20040039066 Administering hydroxytyrosol and oleuropein in a ratio of 1:1-200:1
02/26/2004US20040039061 Suppress expression and induction of inflammatory cytokines, cell adhesion molecule gene and virus and suppressors for nuclear factor kappa beta (nf-kb)
02/26/2004US20040039058 Identifying a mammal having elevated concentrations of tumor necrosis factor- alpha and administering stearidonic acid (18:4, n-3) over a time period
02/26/2004US20040039055 Ameliorate the negative side effects of a serum concentration of a drug higher than that used in normal clinical practice
02/26/2004US20040039046 Scyphostatin analogues as SMase inhibitors
02/26/2004US20040039038 Biaromatic compound activators of PPARy-type receptors
02/26/2004US20040039033 Administering (1-phenyl-2-heteroaryl)ethyl-guanidine compounds for treating ischemic conditions including myocardial infarction, congestive heart failure, and cardiac arrhythmias
02/26/2004US20040039029 Thiazolyl urea compounds and methods of uses
02/26/2004US20040039022 Storage stable mixtures of (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol, water, buffers and chelate compounds used as neuroprotectants
02/26/2004US20040039018 CETP inhibitors in combination with antihypertensive agents and uses thereof
02/26/2004US20040039017 Heterocyclic amines such as 2-(3-(4-Chloro-3-trifluoromethyl-benzylamino)prop-1-ylamino)-1H-quinolin-4 -one, used as G-protein coupled receptor inhibitors, for prophylaxis of cardiovascular disorders, schizophrenia or diabetes
02/26/2004US20040039015 Estrogen Receptor-beta ligands
02/26/2004US20040039007 Nitrogen compounds such as (6-(3-Methylaminopropyl)-2-(2-tri-fluoromethylphenyl)pyrimidin-4-yl)-(1H -pyrazolo(3,4-b)pyridin-3-yl)-amine, use as glycogen synthase kinase-3 (GSK-3) antagonists
02/26/2004US20040039006 (2S)-2-(Adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester, its preparation and its use
02/26/2004US20040039004 Nitrogen compounds such as 4-(5-amino-7-phenethyl-7H-pyrazolo (4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-2-yl)-phenol, used as adenosine receptor antagonists, for prophylaxis of nervous, cardiovascular, respiratory, urogenital and immune disorders
02/26/2004US20040039001 2-guanidino-4-aryl-quinazoline
02/26/2004US20040038979 Novel 6-heteroarylphenanthridines
02/26/2004US20040038978 Chemical compounds
02/26/2004US20040038976 S,N-diarylsulfonamide derivatives; treating inflammatory diseases such as Celiac's disease, Crohn's disease or colitis.
02/26/2004US20040038974 Antiarthritic agents
02/26/2004US20040038969 Substituted aminopyrimidines and aminopyridazines; analgesics particularly for migraines, neuropathic pain and associated hyperalgesia and allodynia; antiinflammatory agents; treating asthma, gastrointestinal disorders, etc.
02/26/2004US20040038964 Imidazole derivatives as raf kinase inhibitors
02/26/2004US20040038963 5,5-Difluoro-3(S)-(pyrimidin-5-yl)-9-(5,6,7,8-tetrahydro-(1, 8)-naphthyridin-2-yl)-nonanoic acid; inhibition of bone resorption, restenosis, angiogenesis, retinopathy, macular degeneration, arthritis, metastatic tumor growth, etc.
02/26/2004US20040038961 Azaisoquinoline derivatives as matrix metalloproteinase inhibitors
02/26/2004US20040038954 Method of treating inflammatory conditions with progesterone or progesterone analogs
02/26/2004US20040038945 Administering pyridoxal-5'-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with a therapeutic cardiovascular compound.
02/26/2004US20040038943 Indole and benzimidazole 15-lipoxygenase inhibitors
02/26/2004US20040038941 Compounds for the treatment of inflammatory disorders
02/26/2004US20040038938 Increasing the survival or growth of motoneurons; treating diseases such as amyotrophic lateral sclerosis, progressive spinal muscular atrophy, infantile muscular atrophy and primary lateral sclerosis.
02/26/2004US20040038928 N-pyrazole A2A receptor agonists
02/26/2004US20040038907 For healing wounds/tissue repair
02/26/2004US20040038906 Endothelin antagonist
02/26/2004US20040038893 Prevention and reduction of blood loss
02/26/2004US20040038889 Fumaric acid amides
02/26/2004US20040038882 Sgk2 and sgk3 used as diagnostic and therapeutic targets
02/26/2004US20040038879 For therapy and prophylaxis of infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, cancers, anorexia, bulimia, asthma, Parkinson's disease, acute heart failure