Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
12/1994
12/06/1994US5371088 1-aryl-4-piperazinylcyclohexanecarbonitriles, the preparation and use thereof
12/06/1994CA2005072C Antispasmodic agent comprising creosote or its phenol derivative
12/06/1994CA1333394C Apovincaminic acid derivatives
12/06/1994CA1333363C Angiogenesis inhibitor comprising fumagillin
11/1994
11/30/1994EP0626382A1 Substituted 2,4-Imidazolidinediones as antihypertensive and antiatherosclerotic agents
11/30/1994EP0625987A1 Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
11/30/1994EP0625981A1 Azabicyclo compounds as calcium channel antagonists
11/30/1994EP0625979A1 Azabricyclic compounds as calcium channel antagonists
11/30/1994EP0625977A1 Piperazine derivatives as 5-ht1a antagonists
11/30/1994EP0625969A1 Arylalkoxyphenoxy-imidazoline compounds
11/30/1994EP0625902A1 Method of treating abnormal tissue proliferation by administering an angiotensin ii antagonist
11/30/1994EP0531410B1 (+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(fluorophenyl)ethyl]-4-piperidinemethanol
11/30/1994CN1095720A Derivatives of benzoylecgonine, ecgonine and ecgonidine and methods for preparing and using same
11/30/1994CN1095716A Novel compounds
11/30/1994CN1095619A Health-care tortoise and soft-shelled turtle capsule and its prepn. method
11/30/1994CN1026791C The diastereoselective preparation of phosphinate esters
11/29/1994US5369114 Angiotensin II antagonist
11/29/1994US5369110 Biphenylyl compounds
11/29/1994US5369103 Piperazine derivatives
11/26/1994CA2124057A1 Substituted 2,4-imidazolidinediones
11/24/1994WO1994027133A1 Method for selective opening of abnormal brain tissue capillaries
11/24/1994WO1994026921A1 Production of toxin binding biopolymers, use thereof
11/24/1994WO1994026891A2 Purified mammalian flt3 ligands and agonists and antagonists thereof
11/24/1994WO1994026888A1 Inhibition of proliferation of vascular smooth muscle cell
11/24/1994WO1994026760A1 SIALYL Lex ANALOGUES AS INHIBITORS OF CELLULAR ADHESION
11/24/1994WO1994026747A1 Ampa antagonists and a method of treatment therewith
11/24/1994WO1994026738A1 N'-heterocyclyl-n-benzofuranyl urea derivatives and their analogs as acat inhibitors
11/24/1994WO1994026735A1 Substituted pyrrolidin-3-yl-alkyl-piperidines useful as tachykinin antagonists
11/24/1994WO1994026732A1 Carbostyril derivatives
11/24/1994WO1994026719A1 Mercapto-amide derivatives useful as neutral endopeptidase and ace inhibitors
11/24/1994WO1994026713A1 DERIVATIVES OF β, β-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS
11/24/1994WO1994026709A1 GUANIDINE DERIVATIVES AS INHIBITORS OF Na+/H+ EXCHANGE IN CELLS
11/24/1994WO1994026707A1 Vitamin d amide derivatives
11/24/1994WO1994026702A1 N-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
11/24/1994WO1994026664A1 Large potassium bicarbonate crystals and process for the preparation thereof
11/24/1994WO1994026307A1 Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine-mediated toxicity
11/24/1994WO1994026303A1 Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
11/24/1994WO1994026301A1 New peptide antagonists at glutamate and nmda receptors
11/24/1994WO1994026298A1 Methods for treating muscle diseases and disorders
11/24/1994WO1994026297A1 Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates
11/24/1994WO1994026291A1 Therapeutic inhibitor of vascular smooth muscle cells
11/24/1994WO1994026278A1 Aurintricarboxylic acid fractions and analogues with anti-angiogenic activity and methods of use
11/24/1994WO1994026277A1 Inhibition of tumor necrosis factor and nitric oxide production by retinoic acid
11/24/1994WO1994026269A1 Methods and compositions for treating asthma, atherosclerosis andinflammatory diseases using optically pure (-)-zileuton
11/24/1994WO1994026268A1 Methods and compositions using optically pure (+)-zileuton
11/24/1994WO1994026249A1 Compositions and methods for reparation and prevention of fibrotic lesions
11/24/1994CA2455985A1 Therapeutic inhibitor of vascular smooth muscle cells
11/24/1994CA2163234A1 Inhibition of proliferation of vascular smooth muscle cell
11/24/1994CA2163004A1 Guanidine derivatives as inhibitors of na+/h+ exchange in cells
11/24/1994CA2163001A1 Derivatives of .beta.,.beta.-dimethyl-4-piperidineethanamine as inhibi tors of the cholesterol biosynthesis
11/24/1994CA2162990A1 Inhibition of tumor necrosis factor and nitric oxide production by retinoic acid
11/24/1994CA2162478A1 Sialyl lex analogues as inhibitors of cellular adhesion
11/24/1994CA2162272A1 Vitamin d amide derivatives
11/24/1994CA2162055A1 Method for selective opening of abnormal brain tissue capillaries
11/24/1994CA2161978A1 Methods and compositions for treating asthma, atherosclerosis and inflammatory diseases using optically pure (-)-zileuton
11/24/1994CA2161777A1 Methods and compositions using optically pure (+)-zileuton
11/24/1994CA2161648A1 Compositions and methods for reparation and prevention of fibrotic lesions
11/24/1994CA2139332A1 Carbostyril derivatives
11/23/1994EP0625048A1 Synthesis of human procollagens and collagens in recombinant dna systems
11/23/1994EP0549666B1 Novel aminobenzosultam derivatives as lipoxygenase inhibitors
11/23/1994EP0543892B1 N-(mercaptoalkyl)ureas and carbamates
11/23/1994EP0522013B1 Novel vitamin d analogues
11/23/1994EP0429464B1 Bivalent ligands effective for blocking acat enzyme
11/23/1994CN1095417A Improvements in or relating to organic compounds
11/23/1994CN1095378A 3-(6-Qinolylmethyl)-4H-imidazol-4-one derivatives, their preparation and their application in therapy
11/23/1994CN1095375A Novel sulfonamides
11/23/1994CN1095374A Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease
11/22/1994US5367081 Vasodilator, antiallergen
11/22/1994US5367059 Cys-Ser-Val-Thr-Cys-Gly specific tumor cell adhesion receptor
11/22/1994US5366997 Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs
11/22/1994US5366994 Enzyme inhibitors
11/22/1994US5366992 Benzoic acid substituted derivatives having cardiovascular activity
11/22/1994US5366987 Enzyme inhibitors, anticholesterol
11/22/1994US5366981 N-acyl-substituted azacyclic compounds, processes for their preparaion, and their use as pharmaceuticals
11/22/1994US5366973 Mercaptoacetylamido pyridazo [1,2]pyridazine, pyrazolo[1,2]pyridazine pyrazolo[1,2]pyridazine, pyridazol[1,2-a][1,2]diazepine and pyrazolol[1,2-a][1,2]diazepine
11/17/1994EP0624596A2 Tetrazole derivatives of bile acids, a process for their production and their use as medicines
11/17/1994EP0624595A2 Nor-derivation of bile-acids, a process for their production and their use as medicines
11/17/1994EP0624594A2 Monomeric bile acid derivatives, a process for their production, and their use as medicines
11/17/1994EP0624590A1 N-acylated staurosporine derivatives, process and intermediates for their preparation and their use as medicaments
11/17/1994EP0624589A2 Intermediates useful in the preparation of pyranyl cyanoguanidine derivatives and methods of preparing same
11/17/1994EP0624588A1 New quinoline derivatives with pharmacological activity
11/17/1994EP0624586A1 Substituted pyrroles
11/17/1994EP0624584A1 Piperazine derivatives useful as calmodolin inhibitors
11/17/1994EP0624583A1 Substituted mono- and bipyridylmethylpyridone as angiotensine II antagonists
11/17/1994EP0624582A1 Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them
11/17/1994EP0624581A2 4-Substituted benzopyran and related compounds useful as pharmaceutical agents
11/17/1994EP0624575A1 Substituted indoles and pharmaceutical compositions containing them
11/17/1994EP0624569A1 NMDA antagonists
11/17/1994EP0624371A1 Microcapsules for controlled release of acetylsalicylic acid
11/17/1994EP0624194A1 Polypeptides derived from human aiv apolipoprotein, preparation and use thereof
11/17/1994EP0624164A1 Peptides with organo-protective activity, process for their preparation and their use in the therapy
11/17/1994EP0624159A1 Pyridyl substituted imidazoles
11/17/1994EP0624094A1 Use of fibroblast growth factors as neuroprotective and neuromodulatory agents
11/17/1994EP0624088A1 Amino acids useful as inhibitors of the advanced glycosylation of proteins
11/16/1994CN1095064A 1,4-benzoxazino derivatives
11/16/1994CN1095062A Preparation of pure enantiomorisomer
11/15/1994US5364942 Sulphonylbenzyl-substituted imidazopyridines
11/15/1994US5364882 Acyloenzyme a: cholesterol acyltransferase inhibitors, anticholesterol
11/15/1994US5364880 Compound for treatment of cardiac arrhythmia, synthesis, and methods of use
11/15/1994US5364868 Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them