Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
06/1999
06/09/1999EP0920330A1 hCG AND DERIVATIVES AS MATRIX METALLOPROTEASES INHIBITORS
06/09/1999EP0920326A1 Antithrombotic materials and methods
06/09/1999EP0920253A1 Il-8 receptor antagonists
06/09/1999EP0752981B1 Substituted cyclopentylamine derivatives and their use as calcium channel antagonists
06/09/1999EP0751932B1 Vitamin-d amide derivatives
06/09/1999EP0626963B1 Vinylene-azaindole derivatives and process for their preparation
06/09/1999CN1219174A Inhibitors of protein farnesyl transferase
06/09/1999CN1219173A Pyrroloazepine compounds
06/09/1999CN1219172A Novel benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists
06/09/1999CN1219170A Substituted 1,2,3,4-tetrahydronaphthalene derivatives
06/09/1999CN1219166A Biphenylsulfonamide matrix metalloproteinase inhibitors
06/09/1999CN1219128A Method of increasing nitric oxide synthesis
06/09/1999CN1219125A Intracoronary stents fixing mould containing quinazolinone derivatives
06/09/1999CN1219103A Antibiotic cocktail and method of use
06/09/1999CN1218801A Tri-substituted imidazoles, and process of their preparation and using the same and having their pharmic composition
06/09/1999CN1043576C Pyrido (1,2,3-de) quinoxaline derivatives, process for preparing the same and their use in medicine
06/09/1999CN1043574C Heterocyclic amines having central nervous system activity
06/08/1999US5910592 Substituted thiazolidinedione derivatives
06/08/1999US5910574 Human trk receptors and neurotrophic factor inhibitors
06/08/1999US5910494 Hypolipidemic 1,4-benzothiazepine-1,1-dioxides
06/08/1999US5910484 Administering hypothalamic inhibitory factor (hif) which has a positive inotropic effect and dilates the coronary arteries to a greater effect than ouabain
06/08/1999US5910437 Ligated d-protein of formula r-l-r' where r and r' are peptides and l is linking group of thiol ester or selenol ester; for production of chirally pure chemicals and drugs; production of racemic crystals; prolonged half-life in body
06/08/1999US5910430 Isolated nucleic acid encoding G-protein coupled receptor (HTADX50)
06/08/1999US5910416 Adrenomedullin
06/08/1999US5910307 Process of extracting and purifying biologically effective ingredients from combined medicinal plants and their extract composition
06/08/1999CA2255165A1 Benzothiophene derivatives useful in therapy
06/08/1999CA2242308A1 Novel compounds
06/03/1999WO1999027111A1 Desaturase genes and their use
06/03/1999WO1999026945A1 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS
06/03/1999WO1999026943A1 Thrombin receptor antagonists
06/03/1999WO1999026929A1 Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
06/03/1999WO1999026926A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
06/03/1999WO1999026921A1 SUBSTITUTED β-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS
06/03/1999WO1999026659A1 Combination of an aldose reductase inhibitor and a glycogen phosphorylase inhibitor
06/03/1999WO1999026652A1 Mucosal delivery system comprising lipophilic thrombin inhibitors
06/03/1999WO1999026651A1 ribH
06/03/1999WO1999026650A1 ribB
06/03/1999WO1999026646A1 ribA
06/03/1999WO1999026628A1 Use of substituted 11-phenyl-dibenzazepine compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhea and scour
06/03/1999WO1999026624A1 Use of substituted diphenyl indanone, indane and indole compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhe and scours
06/03/1999WO1999026620A1 Choline esters of fatty acids and their use in the treatment of stroke
06/03/1999WO1999026616A1 Benzenesulfonamide inhibitors of pde-iv and their therapeutic use
06/03/1999WO1999026615A1 Cyclic amino acid derivatives as cell adhesion inhibitors
06/03/1999WO1999026614A1 Substituted 2-aminoacetamides and the use thereof
06/03/1999WO1999026611A1 Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
06/03/1999WO1999026606A2 SUSTAINED RELEASE FORMULATIONS COMPRISING α-GLUCOSIDASE-INHIBITORS
06/03/1999WO1999026583A2 Inhibtion of lipoprotein oxidation
06/03/1999WO1999018939A9 Methods of treating capsules and dry, powdered pharmaceutical formulations
06/03/1999WO1999007729A3 Peptides having potassium channel opener activity
06/03/1999CA2311969A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors
06/03/1999CA2311498A1 Choline esters of fatty acids and their use in the treatment of stroke
06/03/1999CA2311472A1 Desaturase genes and their use
06/03/1999CA2311129A1 Use of substituted diphenyl indanone, indane and indole compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhea and scours
06/03/1999CA2310775A1 Mucosal delivery system comprising lipophilic thrombin inhibitors
06/03/1999CA2310773A1 Use of substituted 11-phenyl-dibenzazepine compounds for the treatment or prevention of sickle cell disease, inflammatory diseases characterized by abnormal cell proliferation, diarrhea and scour
06/03/1999CA2310750A1 Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation
06/03/1999CA2310069A1 Combination of an aldose reductase inhibitor and a glycogen phosphorylase inhibitor
06/03/1999CA2309341A1 Substituted .beta.-alanine derivatives as cell adhesion inhibitors
06/03/1999CA2309338A1 Cyclic amino acid derivatives as cell adhesion inhibitors
06/03/1999CA2309204A1 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as .alpha.v.beta.3 antagonists
06/03/1999CA2303864A1 Inhibition of lipoprotein oxidation
06/02/1999EP0918875A1 Novel internal ribosome entry site and vector containing same
06/02/1999EP0918777A1 SELECTED DERIVATIVES OF K-252a
06/02/1999EP0918771A1 Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
06/02/1999EP0918761A1 Certain amido- and amino-substituted benzylamine derivatives; a new class of neuropeptite y1 specific ligands
06/02/1999EP0918759A1 Novel thiazolidone-2 derivatives, 4-diketone substituted, method for obtaining them and pharmaceutical compositions containing same
06/02/1999EP0918544A2 Polymer bile acid resorption inhibitors with simultaneous bile acid adsorbing effect
06/02/1999EP0918527A1 Deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds for use as an antiarrhythmic
06/02/1999EP0918519A1 Therapeutic treatment for vegf related occular diseases
06/02/1999EP0918515A2 USE OF INHIBITORS OF THE CELLULAR Na?+ /H?+ EXCHANGER (NHE) FOR PREPARING A MEDICAMENT FOR NORMALIZING SERUM LIPIDS
06/02/1999EP0630376B1 Condensed indole derivatives as 5-ht4-receptor antagonists
06/02/1999EP0581939B1 N-sulphonyl-2-oxoindole derivatives having affinity for vasopressin and/or ocytocin receptors
06/02/1999EP0548254B1 6- or 7-(imidazolidin-2-ylideneamino)-1,4-benzoxazines as alpha adrenergic agents
06/02/1999DE19752952A1 Thienopyrimidine Thienopyrimidines
06/02/1999CN1218471A Carboline derivatives
06/02/1999CN1218467A Sulphur derivatives comprising amide bond, method for preparing same, use thereof as drugs, and pharmaceutical compositions containing such derivatives
06/02/1999CN1218464A 2,3 disulbstituted-4 (3H)-quinazolinones
06/02/1999CN1218460A Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma'
06/02/1999CN1218456A Irreversible inhibitors of tyrosine kinases
06/02/1999CN1218400A Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
06/02/1999CN1218395A Buccal delivery system
06/02/1999CN1218052A New indole and indazole compounds, process for their preparation and pharmaceutical compositions containing them
06/02/1999CN1218050A Sulfonamide-substituted benzopyran derivates processes for their preparation, their use as medicament, and pharmaceutical preparations comprising them
06/02/1999CN1218047A Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them
06/02/1999CN1043532C The sulphate salt of a substituted triazole, pharmaceutical compositions thereof, and their use in therapy
06/02/1999CN1043527C Improvements in and relating to guantidine derivatives
06/01/1999US5908860 4-carbonylamino-substituted-2,2-dimethyl-3,4-dihydrobenzopyran -3-ols
06/01/1999US5908843 Thrombosis, antiinflammatory agent, arteriosclerosis, antitumor agents
06/01/1999US5908837 Antiinflammatory agent
06/01/1999CA1340570C Process for synthesizing n-alkylated amino-acides and the esters thereof. their use for synthesizing carboxyalkyl dipeptides
06/01/1999CA1340567C Heterocyclic amide derivatives
05/1999
05/27/1999WO1999025829A2 Cdk2 protein and cdk2 protein complexes
05/27/1999WO1999025715A1 Preparation of terazosin hydrochloride dihydrate
05/27/1999WO1999025714A1 Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance p antagonists
05/27/1999WO1999025709A1 Isoquinoline derivatives and their therapeutical use
05/27/1999WO1999025701A1 NOVEL HETEROCYCLICALLY SUBSTITUTED α-HYDROXYCARBOXLIC ACID DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS
05/27/1999WO1999025687A1 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
05/27/1999WO1999025686A1 Cyclic amine derivatives and their use as drugs
05/27/1999WO1999025683A1 Position-4 substituted 2-pyrrolidinone derivatives to reduce the level of extracellular glutamate
05/27/1999WO1999025374A1 Combination of hypertensin converting enzyme inhibitor with a diuretic for treating microcirculation disorders