Patents for A61P 3 - Drugs for disorders of the metabolism (129,789)
06/1999
06/23/1999EP0923580A1 Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof
06/23/1999EP0923530A1 Inhibition of matrix metalloproteases by substituted biaryl oxobutyric acids
06/23/1999EP0923382A1 Compositions of plant carbohydrates as dietary supplements
06/23/1999EP0923377A1 Therapeutic uses for an aminosterol compound
06/23/1999EP0639186B1 Taxol derivatives
06/23/1999CN1220658A Galcium receptor-active compound
06/23/1999CN1220656A Novel trienoic retinoid compounds and method
06/23/1999CN1220600A Tetrahydrolipstatin-containing compositions
06/23/1999CN1220266A Intermediates of protein kinase C inhibitors and preparation process thereof
06/23/1999CN1043763C Tropane-aldoxine derivatives and preparation process and use thereof
06/22/1999US5914347 By adding to a hydroxyalkyl cellulose, evaporating the solution or dispersion to dryness under an inert atmosphere to prepare a powder; imparts oxidation resistance
06/22/1999US5914329 Dimesylate salts of neuropeptide Y ligands
06/22/1999US5914323 Treating hypercalcemia of malignancy, metastatic bone disease and/or metabolic bone disease by administering an isotonic aqueous alendronate solution with a buffer to maintain the ph in the range 4 to 8 to prevent precipitation
06/22/1999US5914130 In specifies rahges as a swallowable pills, caplets, tabletsor capsules to reduce body acid
06/22/1999US5914106 Interleukin-6 receptor agonists
06/22/1999CA2151674C Methods of administering crf antagonists
06/17/1999WO1999029878A2 Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
06/17/1999WO1999029856A1 Restin and methods of use thereof
06/17/1999WO1999029855A1 Mutants of endostatin, 'em 1' having anti-angiogenic activity and methods of use thereof
06/17/1999WO1999029685A1 (e)-3-[1-n-butyl- 5-[2-(2-carboxyphenyl)methoxy- 4-chlorophenyl]-1h- pyrazol-4-yl]-2-[(5- methoxy-2,3- dihydrobenzofuran-6-yl)methyl]- prop-2-enoic acid monoargininyl salt
06/17/1999WO1999029673A1 SELECTIVE β3 ADRENERGIC AGONISTS
06/17/1999WO1999029672A1 SELECTIVE β3 ADRENERGIC AGONISTS
06/17/1999WO1999029669A1 Urethanes derived from azacycloalkanes, thio and dithio analogues, production and use thereof as 2,3 epoxysqualene lanesterol cyclase inhibitors
06/17/1999WO1999029662A2 Urethanes, thio and dithio analogues, the salts thereof, medicaments containing said compounds, use and method for the production thereof
06/17/1999WO1999029336A1 Glp-1 formulations
06/17/1999WO1999029333A1 Compositions and methods for weight reduction
06/17/1999WO1999029332A1 Compositions for weight reduction
06/17/1999WO1999029324A1 Preventives/remedies for diabetes
06/17/1999WO1999029321A1 Inhibition of membrane-associated viral replication
06/17/1999WO1999029317A1 Methods and compositions for treating diabetes
06/17/1999WO1999029316A1 Pharmaceutical compositions containing an omega-3 fatty acid oil
06/17/1999WO1999029314A1 Novel salts of metformin and method
06/17/1999WO1999029308A2 Method for combating obesity
06/17/1999WO1999017787A3 Use of a chemically-stabilized chlorite solution for inhibiting an antigen-specific immune response
06/17/1999DE19754796A1 Neue, von Azacycloalkanen abgeleitete Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung New-derived azacycloalkanes urethanes, their thio and Dithioanaloga, salts thereof, pharmaceutical compositions containing them and their use, and processes for their preparation
06/17/1999DE19754795A1 Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung New urethanes, their thio and Dithioanaloga, salts thereof, pharmaceutical compositions containing them and their use, and processes for their preparation
06/17/1999CA2313705A1 Restin and methods of use thereof
06/17/1999CA2313626A1 Methods and compositions for treating diabetes
06/17/1999CA2313251A1 Mutants of endostatin, "em 1" having anti-angiogenic activity and methods of use thereof
06/17/1999CA2312987A1 Selective .beta.3 adrenergic agonists
06/17/1999CA2312965A1 (e)-3-¬1-n-butyl-5-¬2-(2-carboxyphenyl)methoxy-4-chlorophenyl|-1h-pyrazol-4-yl|-2-¬(5-methoxy-2,3-dihydrobenzofuran-6-yl)methyl|-prop-2-enoic acid monoargininyl salt
06/17/1999CA2312849A1 Selective .beta.3 adrenergic agonists
06/17/1999CA2312716A1 Medicament for prevention and treatment of diabetes
06/17/1999CA2312423A1 Inhibition of membrane-associated viral replication
06/17/1999CA2312287A1 Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
06/17/1999CA2312190A1 Glp-1 formulations
06/17/1999CA2309388A1 New urethanes derived from azacycloalkanes, the thio and dithio analogues thereof, the salts thereof, pharmaceutical compositions containing these compounds and their use as well as processes for preparing them
06/16/1999EP0921820A1 Gene therapy for obesity
06/16/1999EP0921818A1 Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
06/16/1999EP0921815A1 Therapeutic uses of humanized antibodies against alpha-4 integrin
06/16/1999EP0921798A1 Novel treatment of leptine resistance
06/16/1999EP0921796A1 Tetrahydrolipstatin containing compositions
06/16/1999EP0848736A4 Acid resistant calcium carbonate composition containing an aluminum salt and uses therefor
06/16/1999EP0583421B1 Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
06/16/1999EP0553218B1 Indole derivatives
06/16/1999CN1219928A Novel vitamin D analogues
06/16/1999CN1219873A Remedy or preventive medicine for hyperlipemia
06/16/1999CN1043643C Cyclohexan derivative and its use for preparing medicine
06/16/1999CN1043610C Novel treatment agent
06/16/1999CN1043608C Improvements in or relating to benzothiophenes
06/15/1999US5912325 A polypeptide which codes for an epitope of an animal growth hormone; animal growth enhancer
06/15/1999US5912262 Heterocyclic compounds
06/15/1999US5912005 Methods of use of uncoated gel particles
06/15/1999US5911993 For non-insulin dependent diabetes to lower blood sugar; administering extracts from plants of family crassulaceae, genus sinocressula berger; breaking cell walls of crushed leaves, filtration, form powder from concentrated filtrate
06/15/1999US5911984 Disorders associated with fatty acid metabolism.
06/15/1999CA2136821C Quaternary nitrogen-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism
06/10/1999WO1999028493A2 Method for identifying inhibitors of g-protein coupled receptor hibef51
06/10/1999WO1999027952A1 Anti-hypoxic and anti-ischemic drug
06/10/1999WO1999027890A2 A process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
06/10/1999WO1999007737A3 Lsr receptor, cloning and uses
06/10/1999WO1999005175A3 Diagnosis and treatment of diseases using anti-anti-t-cell receptor vbeta anti-bodies or peptides which are recognized by said antibodies, and endocrine secretion regulatory protein i (esrp1)
06/10/1999DE19754082A1 Methode zur Bekämpfung der Fettleibigkeit Method to combat obesity
06/09/1999EP0921120A1 Selective beta 3 adrenergic agonists
06/09/1999EP0920870A1 Flavanone-containing composition
06/09/1999EP0920865A1 Pharmaceutical compositions containing Norastemizole
06/09/1999EP0920864A1 Combination therapy including a specific beta-3 agonist and an anorectic agent
06/09/1999EP0920863A1 2-Aryl-3-aroylbenzo(b)thiophenes useful for the treatment of estrogen deprivation syndrome
06/09/1999EP0920862A1 2-Arylbenzo b thiophenes useful for the treatment of estrogen deprivation syndrome
06/09/1999EP0920632A1 Materials and methods for detection and treatment of immune system dysfunctions
06/09/1999EP0920528A1 Synthetic protein folding catalysis
06/09/1999EP0920503A2 A novel human leptin receptor gene-related protein
06/09/1999EP0920446A1 Conformationally constrained backbone cyclized somatostatin analogs
06/09/1999EP0920429A1 Substituted pyrido- or pyrimido-containing 6,6- or 6,7-bicyclic derivatives
06/09/1999EP0877563A4 Food and vitamin preparations containing the natural isomer of reduced folates
06/09/1999EP0799035A4 Emulsion suitable for administering a sphingolipid and use thereof
06/09/1999EP0775103B1 Retinoic acid x-receptor ligands
06/09/1999EP0751932B1 Vitamin-d amide derivatives
06/09/1999EP0647636B1 Benzothiazole compound, process for producing the same, and use thereof
06/09/1999EP0615549B1 Process for the preparation of pharmaceutically active thiazolidine or oxazolidine compounds by a yeast reductase
06/09/1999EP0614456B1 1alpha,24(s)-dihydroxy vitamin d2, its formation and use
06/09/1999EP0578723B1 PROCESS FOR PURIFICATION OF HMG-CoA REDUCTASE INHIBITORS
06/09/1999CN1219128A Method of increasing nitric oxide synthesis
06/09/1999CN1218808A Dithio-heterocyclic-pentylene acetamide derivatives
06/09/1999CN1218801A Tri-substituted imidazoles, and process of their preparation and using the same and having their pharmic composition
06/08/1999US5910592 Substituted thiazolidinedione derivatives
06/08/1999US5910508 Novel compounds useful in modulating cellular hormone receptors; treating skin disorders such as acne, psoriasis
06/08/1999US5910494 Hypolipidemic 1,4-benzothiazepine-1,1-dioxides
06/08/1999US5910437 Ligated d-protein of formula r-l-r' where r and r' are peptides and l is linking group of thiol ester or selenol ester; for production of chirally pure chemicals and drugs; production of racemic crystals; prolonged half-life in body
06/08/1999US5910435 Exposing protein with non-native disulfide bonds to non-protein compound with pka less than 8 and eo greater than -0.25 volts; for proper conformation of heterologous eukaryotic proteins from prokaryotic hosts
06/08/1999US5910427 Protein derivatives formed by replacement, substitution, or chemical modification of amino acids 57 and/or 60 having increased activity; for immunosuppressives/allergy treatments