Patents for A61P 27 - Drugs for disorders of the senses (53,017)
06/1999
06/17/1999WO1999029856A1 Restin and methods of use thereof
06/17/1999WO1999029855A1 Mutants of endostatin, 'em 1' having anti-angiogenic activity and methods of use thereof
06/17/1999WO1999029841A1 Purification and microsequencing of hyaluronidase isozymes
06/17/1999WO1999029694A1 Purine compounds having pde iv inhibitory activity and methods of synthesis
06/17/1999WO1999029339A2 Prevention and/or treatment of allergic conditions
06/17/1999WO1999029315A1 Taurine derivatives usable in the treatment of ophthalmic disorders
06/17/1999CA2313705A1 Restin and methods of use thereof
06/17/1999CA2313348A1 Soluble inhibitors of vascular endothelial growth factor and use thereof
06/17/1999CA2313251A1 Mutants of endostatin, "em 1" having anti-angiogenic activity and methods of use thereof
06/17/1999CA2313150A1 Purine compounds having pde iv inhibitory activity and methods of synthesis
06/17/1999CA2312287A1 Methods of producing anti-angiogenic proteins: endostatin, angiostatin or restin, using a pichia yeast expression system
06/17/1999CA2311283A1 Purification and microsequencing of hyaluronidase isozymes
06/16/1999EP0922044A1 Pyrrolo(3,2-c) quinoline derivatives
06/16/1999EP0921806A1 Mannose-6-phosphate composition and its use in treating fibrotic disorders
06/16/1999EP0921801A1 Inhibitors of farnesyl-protein transferase
06/16/1999EP0921797A1 Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for lowering intraocular pressure
06/16/1999CN1219872A Compositions and method for treating or preventing diseases of body passageways
06/16/1999CN1219391A Choline antagonist sticking preparation
06/15/1999US5912360 Dioxolane intermediates
06/15/1999US5912270 Anti-inflammatory compounds
06/10/1999WO1999028475A2 Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
06/10/1999WO1999028300A1 Substituted imidazole derivatives having agonist-like activity at alpha 2b or 2b/2c adrenergic receptors
06/10/1999WO1999027927A1 Synergistic antimicrobial compositions
06/10/1999WO1999027890A2 A process for the preparation of ring-opened epothilone intermediates which are useful for the preparation of epothilone analogs
06/10/1999CA2312811A1 Synergistic antimicrobial compositions
06/10/1999CA2312334A1 Substituted imidazole derivatives having agonist-like activity at alpha 2b or 2b/2c adrenergic receptors
06/10/1999CA2309228A1 Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
06/09/1999EP0920872A1 Use of rosmarinus officinalis for treating various diseases
06/09/1999EP0920425A1 Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
06/09/1999EP0920330A1 hCG AND DERIVATIVES AS MATRIX METALLOPROTEASES INHIBITORS
06/09/1999EP0920315A1 Treatment of upper airway allergic responses with a combination of histamine receptor antagonists
06/09/1999EP0763012B1 Succinyl hydroxamic acid, n-formyl-n-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors
06/09/1999EP0630232B1 Method of treatment for nasal and sinus dysfunction, and horseradish preparation therefor
06/09/1999CN1219130A Composition comprising a nitrone compound for use in treating ocular inflammation
06/08/1999US5910510 Administering a photoactive absorber, e.g. a porphyrin, and waiting to have it localize in ocular tissue; radiating with laser light; macular degeneration; treating neovascularization
06/03/1999WO1999026942A1 5-(2-imidazolinylamino)-benzimidazole derivatives, their preparation and their use as .alpha.-adrenoceptor agonists with improved metabolic stability
06/03/1999WO1999026924A1 Substituted oximes as neurokinin antagonists
06/03/1999WO1999026921A1 SUBSTITUTED β-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS
06/03/1999WO1999026651A1 ribH
06/03/1999WO1999026650A1 ribB
06/03/1999WO1999026646A1 ribA
06/03/1999WO1999026629A1 Ep2-receptor agonists as neuroprotective agents for the eye
06/03/1999WO1999012566A9 HUMANIZED ANTIBODIES TO HUMAN gp39, COMPOSITIONS CONTAINING AND THERAPEUTIC USE THEREOF
06/03/1999WO1999011275A3 Use of immunostimulatory oligonucleotides for preventing or reducing antigen-stimulated, granulocyte-mediated inflammation
06/03/1999WO1999005096A3 Urokinase inhibitors
06/03/1999CA2309341A1 Substituted .beta.-alanine derivatives as cell adhesion inhibitors
06/02/1999EP0918795A1 Antiangiogenic drug to treat cancer, arthritis and retinopathy
06/02/1999EP0918538A1 Use of proteolytic enzymes for treating uveitis
06/02/1999EP0918529A1 Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
06/02/1999EP0918519A1 Therapeutic treatment for vegf related occular diseases
06/02/1999EP0918460A1 Methods of treatment of eye trauma and disorders
06/02/1999EP0648131B1 Ophthalmic compositions and methods for preserving and using same
06/02/1999EP0548254B1 6- or 7-(imidazolidin-2-ylideneamino)-1,4-benzoxazines as alpha adrenergic agents
06/02/1999CN1218464A 2,3 disulbstituted-4 (3H)-quinazolinones
06/02/1999CN1218400A Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
06/02/1999CN1218395A Buccal delivery system
06/02/1999CN1218047A Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them
06/02/1999CN1217918A Chinese medicinal prescription for prevention and treatment of catarct and preparing method thereof
06/02/1999CN1217915A Preparing method for Xiaozhangming eye drops
06/01/1999US5908865 Chlorhexidine gluconate-containing, stabilized aqueous pharmaceutical preparations
06/01/1999US5908851 Derivatives of succinamide and their use as metalloproteinase inhibitor
06/01/1999US5908824 Dispersed homogeneously in and adsorbed homogeneously onto a mucosa protecting and/or tissue repairing agent
06/01/1999CA1340567C Heterocyclic amide derivatives
05/1999
05/27/1999WO1999025687A1 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
05/27/1999WO1999025359A1 New composition of matter
05/27/1999WO1999025358A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
05/27/1999WO1999025348A1 5-ht1f agonists
05/27/1999WO1999003817A3 Aliphatic propargylamines as cellular rescue agents
05/27/1999CA2310630A1 Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
05/27/1999CA2310248A1 5-ht1f agonists
05/27/1999CA2306460A1 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
05/26/1999EP0917875A1 Aqueous eye drops containing apafant as principal agent
05/25/1999US5906989 Cyclopentane(ENE) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
05/20/1999WO1999024423A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999WO1999024421A1 Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
05/20/1999WO1999024419A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999WO1999024408A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/20/1999WO1999024406A1 Phenyl-alkyl-imidazoles as h3 receptor antagonists
05/20/1999WO1999024405A1 H3 receptor ligands of the phenyl-alkyl-imidazoles type
05/20/1999WO1999024404A1 Substituted pyridine compounds as anti-inflammatory agents
05/20/1999WO1999024399A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999WO1999024064A1 Antigen specific to meniere's disease and medical use thereof
05/20/1999WO1999024051A2 Application of vasopressin antagonists for treating disturbances or illnesses of the inner ear
05/20/1999WO1999024024A2 Treatment of t-helper cell type 2 mediated immune diseases with retinoid antagonists
05/20/1999CA2309609A1 Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
05/20/1999CA2309162A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999CA2309121A1 Phenyl-alkyl-imidazoles as h3 receptor antagonists
05/20/1999CA2309117A1 Application of vasopressin antagonists for treating disturbances or illnesses of the inner ear
05/20/1999CA2308586A1 H3 receptor ligands of the phenyl-alkyl-imidazoles type
05/20/1999CA2308361A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999CA2308359A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999CA2308358A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/20/1999CA2276080A1 Antigen specific to meniere's disease and medical use thereof
05/19/1999EP0916729A2 Novel reductase
05/19/1999EP0916727A2 Novel LysS
05/19/1999EP0916670A2 Pyrrolo-(3,2-b) pyridines and their use as 5-HT1F agonists
05/19/1999EP0915974A1 Modified tie-2-receptor ligands
05/19/1999EP0915823A1 Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses
05/19/1999EP0915704A1 Use of phosphinyloxyalkyl and phosphonamidoalkyl derivatives of cyclopentane(ene) as therapeutic agents
05/19/1999EP0915702A2 Use of a dehydroepiandrosterone derivative for enhancing or accelerating re-epithelialization or re-endothelialization of a tissue