Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
03/1998
03/19/1998WO1998011062A1 Benzamidine derivatives and the use thereof as medicaments with ltb4-antagonistic effect
03/19/1998WO1998010792A1 Immune direction therapy
03/19/1998WO1998010787A2 Pharmaceutical compositions for the treatment of immune disorders
03/19/1998WO1998010783A1 Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions
03/19/1998WO1998010775A1 Composition and method for repairing neurological tissue
03/19/1998WO1998010762A2 Controlled release dosage form of r-(z)-alpha-methoxyimino-alpha-(1-azabicyclo2.2oct-c-yl)acetonitrile monohydrochloride
03/19/1998WO1998010759A1 Method of producing analgesia
03/19/1998WO1998010652A1 NOVEL trpS
03/19/1998WO1998004289A3 Pharmaceutical composition containing a 5ht2c antagonist and a d2 antagonist
03/19/1998DE19637237A1 Piperazin-Derivate Piperazine derivatives
03/19/1998DE19637123A1 Neue Pyranosidderivate New Pyranosidderivate
03/19/1998CA2266469A1 Method of producing analgesia
03/19/1998CA2265928A1 C-terminal modified (n-substituted)-2-indolyl dipeptides as inhibitors of the ice/ced-3 family of cysteine proteases
03/19/1998CA2265885A1 Pharmaceutical compositions for the treatment of immune disorders
03/19/1998CA2265661A1 Controlled release dosage form of r-(z)-alpha-methoxyimino-alpha-(1-azabicyclo2.2.2oct-c-yl)acetonitrile monohydrochloride
03/19/1998CA2265509A1 3-substituted pyrido(4',3':4,5)thieno(2,3-d)pyrimidine derivatives, their preparation and their use
03/19/1998CA2265467A1 Ptx sensitive g proteins, the production and use thereof
03/19/1998CA2264966A1 Expression of an exogenous gene in a mammalian cell by use of a non-mammalian dna virus having an altered coat protein
03/19/1998CA2264748A1 Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions
03/19/1998CA2264541A1 Human protein kinases
03/19/1998CA2262818A1 Modified amino acids, pharmaceuticals containing these compounds and methods for their production
03/19/1998CA2259283A1 Method for treating amyotrophic lateral sclerosis
03/19/1998CA2237314A1 Novel tricyclic compounds for the inhibition of the ice/ced-3 protease family of enzymes
03/18/1998EP0829481A1 Morphinan hydroxamic acid compounds
03/18/1998EP0829480A2 Tetrazolyl-substituted quinuclidines as substance P antagonists
03/18/1998EP0828851A2 Tripeptidylpeptidase inhibitors
03/18/1998EP0828746A1 Novel quinoxaline dione derivatives, their production and their use in medicaments
03/18/1998EP0828730A1 Piperazine derivatives
03/18/1998EP0828724A1 Diaryl-5-oxygenated-2-(5h)-furanones as cox-2 inhibitors
03/18/1998EP0828722A1 Process for making heterocyclic compounds
03/18/1998EP0828712A1 Beta-adrenergic agonists
03/18/1998EP0828513A2 Combinations for the treatment of parkinsonism containing selective nmda antagonists
03/18/1998EP0828504A2 Method for treating huntington's disease using glial cell line-derived neurotrophic factor (gdnf) protein product
03/18/1998EP0828494A1 Method for treating cognitive dysfunction
03/18/1998EP0828489A1 Smoking cessation treatments using naltrexone and related compounds
03/18/1998EP0828486A1 Use of pyrrolidine derivatives for treating alcoholism
03/18/1998EP0828485A1 Use of r-enantiomer of n-propargyl-1-aminoindan, salts, and compositions thereof
03/18/1998EP0828483A1 Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase
03/18/1998EP0674512B1 Application of riluzole in the treatment of neurological lesions related to traumatic injuries
03/18/1998EP0619734B1 New pharmaceutical formulations of 5-(2-chloro-1-hydroxyethyl)-4-methylthiazole
03/18/1998EP0544773B1 Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
03/18/1998CN1176646A CCK or gastrin modulating 5 -heterocyclic-1, 5-benzodiazepines
03/18/1998CN1176638A 4-aminotetrahydrobenzisoxazole or-isothiazole compounds
03/18/1998CN1176598A Method and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
03/18/1998CN1176101A N -(4 -aryl -thiazol -2 -yl) -sulphonamide derivatives and their use
03/17/1998US5728885 Forming free base by reacting with caustic soda, salt forming and precipitating with tartaric acid, releasing free base from tartrate salt by caustic soda, forming salt, releasing free base, reacting with diisobutylaluminum hydrate
03/17/1998US5728846 Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives
03/17/1998US5728829 Multistage reaction of n-protected benzotriazolyl glycine derivative with aminoketone, then reaction with ammonia and acid catalyzed cyclization
03/17/1998US5728819 Secreted proteins and polynucleotides encoding them
03/17/1998US5728803 Pantropic neurotrophic factors
03/17/1998US5728728 Administering felbamate to human having sepsis, hiv dementia, meningitis or central nervous system vasculitis, which is a neuronal cell protecting antagonist of glycine site of n-methyl-d-aspartate receptor complex
03/17/1998US5728716 Trachykinin peptide for nervous system disorders and cardiovascular disorders
03/17/1998US5728708 Pharmacologically active pyridine derivatives and processes for the preparation thereof
03/17/1998US5728704 Substituted pyridmidines for control of diabetic complications
03/17/1998US5728695 Tachykinin antagonists useful in treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia
03/17/1998US5728688 Therapeutic methods and delivery systems utilizing sex steroid precursors
03/12/1998WO1998010058A1 Human cns cell lines and methods of use therefor
03/12/1998WO1998009985A2 Anti-inflammatory peptides and uses thereof
03/12/1998WO1998009984A1 Central nervous system-derived immune privilege factor and uses thereof
03/12/1998WO1998009980A1 Bh3 interacting domain death agonist
03/12/1998WO1998009961A1 Indazole derivatives and their use as inhibitors of phosphodiesterase (pde) type iv and the production of tumor necrosis factor (tnf)
03/12/1998WO1998009940A1 Biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases
03/12/1998WO1998009938A1 N-substituted-2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity
03/12/1998WO1998009653A1 Association of no syntase inhibitors with trappers of oxygen reactive forms
03/12/1998WO1998009630A1 Compounds and methods
03/12/1998WO1998009626A1 Methods for in vivo reduction of iron levels and compositions useful therefor
03/12/1998WO1998009625A1 SELECTIVE β3 ADRENERGIC AGONISTS
03/12/1998DE19636769A1 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung 3-substituted pyrido [4 ', 3': 4,5] thieno [2,3-d] pyrimidine derivatives, their preparation and use
03/12/1998DE19636689A1 Neue Benzamidinderivate New benzamidine derivatives
03/12/1998CA2264959A1 Central nervous system-derived immune privilege factor and uses thereof
03/12/1998CA2264942A1 Compounds and methods
03/12/1998CA2264798A1 Indazole derivatives and their use as inhibitors of phosphodiesterase (pde) type iv and the production of tumor necrosis factor (tnf)
03/12/1998CA2264578A1 Bh3 interacting domain death agonist
03/12/1998CA2264285A1 Anti-inflammatory peptides and uses thereof
03/12/1998CA2264273A1 Human cns cell lines and methods of use therefor
03/12/1998CA2263686A1 Methods for in vivo reduction of iron levels and compositions useful therefor
03/12/1998CA2263250A1 N-substituted-2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity
03/11/1998EP0828003A2 Human serine protease
03/11/1998EP0827747A1 Analgetic agent
03/11/1998EP0827746A1 Carbazole analogues as selective B3 adrenergic agonists
03/11/1998EP0827744A2 Use of amino acids for the manufacture of a medicament for inhibiting or activating glutamic acid in the brain
03/11/1998EP0827503A1 Pyrrolidinyl methyl indole salt
03/11/1998EP0827408A1 Method of administration of igf-i
03/11/1998EP0827399A1 Inhibiting photodecomposition of 3-substituted-2-oxindoles
03/11/1998EP0785933B1 Indole derivatives as 5ht1-like agonists
03/11/1998EP0667866B1 1,4-benzothiazepines useful as neurological agents
03/11/1998EP0636125B1 Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists
03/11/1998EP0633879B1 Enantiomeric 1-phenyl-2-(2-pyridinyl)ethylamine for the treatment of neurodegenerative disorders
03/11/1998CN1175976A Arachidonic acid and method for production and use thereof
03/11/1998CN1175944A 1 -aryl -2 -acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists
03/11/1998CN1175903A Method of treating adenosine depletion
03/10/1998US5726316 Pharmaceutical compositions for prevention and treatment of central nervous system disorders
03/10/1998US5726302 Water soluble adenosine kinase inhibitors
03/10/1998US5726208 Heterocyclic tertiary amines
03/10/1998US5726200 Treatment of obesity, gastrointestinal disorders, tumors, drug withdrawal; useful as antipsychotic, antianxiety, antiulcer agents;
03/10/1998US5726193 Method for treating anxiety
03/10/1998US5726188 Optically active imidazolidinone derivatives and processes for preparing them
03/10/1998US5726187 N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists
03/10/1998US5726177 Indole-derived arylpiperazines as ligands for 5HT1 -like, 5HT1B and 5HT1D receptors
03/10/1998US5726175 Imidazo 1,2-A!indeno 1,2-E!pyrazine-2-carboxylic acid derivatives, preparation thereof and drugs containing same