Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
07/1999
07/01/1999WO1999032637A1 Human signal transduction serine/threonine kinase
07/01/1999WO1999032620A1 Insulin-like growth factor binding protein fragments and the utilization thereof
07/01/1999WO1999032615A1 Brain or heart cyclic nucleotide gated ion channel compounds and uses thereof
07/01/1999WO1999032614A1 Secreted proteins and polynucleotides encoding them
07/01/1999WO1999032606A2 Neural precursor cells, method for the production and use thereof in neural defect therapy
07/01/1999WO1999032513A1 Protein binding polypeptides
07/01/1999WO1999032510A1 Kappa receptor opioid peptides
07/01/1999WO1999032484A1 Process for the preparation of paroxetine hydrochloride
07/01/1999WO1999032480A1 Heterocyclic ether and thioether compounds useful in controlling chemical synaptic transmission
07/01/1999WO1999032475A1 Novel sulfonamide substituted chroman derivatives useful as beta-3 adrenoreceptor agonists
07/01/1999WO1999032462A1 Triazine compounds for treatment of cns disorders
07/01/1999WO1999032461A1 1,4-diazacycloheptane derivatives
07/01/1999WO1999032460A1 Substituted 2-aryl-4-amino-chinazolines, method for the production and use thereof as medicaments
07/01/1999WO1999032453A1 POLYCYCLIC α-AMINO-⊂-CAPROLACTAMS AND RELATED COMPOUNDS
07/01/1999WO1999032451A1 Azepine or larger medium ring derivatives and their use as pharmaceuticals
07/01/1999WO1999032448A1 Substituted pyridine and pyridazine compounds and their pharmaceutical use
07/01/1999WO1999032431A1 A NOVEL PHOSPHATE SALT OF ISOPROPYL-METHYL-[2-(3-n-PROPOXYPHENOXY)ETHYL]AMINE
07/01/1999WO1999032430A1 Process for the preparation of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine
07/01/1999WO1999032129A1 Ginkgo biloba leaf extracts with a reduced 4'-o-methylpyridoxine and biflavone content
07/01/1999WO1999032120A1 A method of preventing abuse of opioid dosage forms
07/01/1999WO1999032119A1 Opioid agonist/antagonist combinations
07/01/1999WO1999032117A1 Novel substituted pyridine compounds useful as modulators of acetylcholine receptors
07/01/1999WO1999032111A1 INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS
07/01/1999WO1999032103A1 New use of local anaesthetics against vascular headaches
07/01/1999WO1999019324A3 Antipsychotic substituted piperidine derivatives
07/01/1999WO1999016741A3 Lipophilic diesters of chelating agents
07/01/1999WO1999003817B1 Aliphatic propargylamines as cellular rescue agents
07/01/1999DE19757250A1 Insulin-like growth factor binding protein und seine Verwendung Insulin-like growth factor binding protein and its use
07/01/1999DE19756848A1 Extrakte aus Blättern von Ginkgo biloba mit vermindertem Gehalt an 4'-O-Methylpyridoxin und Biflavonen Extracts from leaves of Ginkgo biloba with a reduced content of 4'-O-methyl and biflavones
07/01/1999CA2315974A1 Insulin-like growth factor binding protein fragments and the utilization thereof
07/01/1999CA2315941A1 Novel substituted pyridine compounds useful as modulators of acetylcholine receptors
07/01/1999CA2315720A1 Inhibition of p38 kinase activity using substituted heterocyclic ureas
07/01/1999CA2315620A1 Triazine compounds for treatment of cns disorders
07/01/1999CA2315301A1 Protein binding polypeptides
07/01/1999CA2315245A1 Secreted proteins and polynucleotides encoding them
07/01/1999CA2315066A1 Process for the preparation of paroxetine hydrochloride
07/01/1999CA2314989A1 A novel phosphate salt of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine
07/01/1999CA2314988A1 Process for the preparation of isopropyl-methyl-¬2-(3-n-propoxyphenoxy)ethyl|amine
07/01/1999CA2314925A1 Novel sulfonamide substituted chroman derivatives useful as beta-3 adrenoreceptor agonists
07/01/1999CA2314452A1 New use of local anaesthetics against vascular headaches
07/01/1999CA2314437A1 Mood disorder gene
07/01/1999CA2312070A1 1,4-diazacycloheptane derivatives
07/01/1999CA2307221A1 Polycyclic .alpha.-amino-e-caprolactams and related compounds
06/1999
06/30/1999EP0926237A2 Nucleic acid constructs for gene therapy, whose activity is influenced by inhibitors of cyclin-dependent kinases
06/30/1999EP0926236A1 Binding partners for inhibitors of cyclin-dependent kinases and their use for inhibitor screening, diagnosis or therapy
06/30/1999EP0926145A1 Napthalene compounds, method for their preparation and pharmaceutical compositions containing them
06/30/1999EP0925357A1 Human cns cell lines and methods of use therefor
06/30/1999EP0925299A1 Pyrazolopyridine compound and pharmaceutical use thereof
06/30/1999EP0925298A1 Substituted 6,6-hetero-bicyclic derivatives
06/30/1999EP0925297A1 Endothelin receptor antagonists
06/30/1999EP0925295A1 N-benzenesulphonyl-l-proline derivatives as bradykinin b2 agonists
06/30/1999EP0925291A1 Spirocyclic dopamine receptor subtype ligands
06/30/1999EP0925071A1 Muc-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions
06/30/1999EP0925067A1 Composition and method for repairing neurological tissue
06/30/1999EP0782567B1 Isothiourea derivatives as no synthase inhibitors
06/30/1999EP0756602B1 Cck or gastrin modulating 5-heterocyclic-1,5-benzodiazepines
06/30/1999EP0699198B1 N-benzoylmethyl substituted paroxetine derivatives
06/30/1999EP0637956B1 Use of remacemide for the treatment of parkinson's disease
06/30/1999CN1221418A Preparation of (7S, trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl) octahydro-2h-pyrido [1,2-A] pyrazine
06/30/1999CN1221417A Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof
06/30/1999CN1221343A Phosphatidic acid-comprising compositions
06/30/1999CN1221341A Use of benzonaphthalene derivatives to make medicaments for treating disease of central nervous system
06/30/1999CN1043893C Pharmaceuticals
06/30/1999CN1043883C Vitamin D analogues, medicinal composition containing the same and medical use thereof
06/29/1999US5917053 Inhibiting gaba release from neurons
06/29/1999US5917047 Heterocyclic compounds
06/29/1999US5916923 Venlafaxine for the treatment of generalized anxiety disorder
06/29/1999US5916906 Compositions comprising nicotinylalanine and an inhibitor of glycine conjugation or vitamin B6
06/29/1999US5916901 Heterocyclic compounds
06/29/1999US5916889 1,4-disubstituted piperazines
06/29/1999US5916887 4-substituted-3-(2-amino-2-cycloalkyl methyl)-acetamido azetidin-2-one derivatives as cysteine proteinase regulators
06/29/1999US5916590 Soft gelatin pharmaceutical dosage form
06/29/1999US5916556 Human MRNA editing enzyme
06/29/1999CA2131722C N,n'-disubstituted amide derivative
06/29/1999CA2130275C Use of substituted adenine derivatives for treating multiple sclerosis
06/24/1999WO1999031268A1 Agonists of metabotropic glutamate receptors and uses thereof
06/24/1999WO1999031252A1 Ubiquitin-like conjugating protein
06/24/1999WO1999031237A1 Apoptosis inhibitory factor
06/24/1999WO1999031232A1 Human brain derived kcnq2 potassium channel
06/24/1999WO1999031230A2 Oligophrenin-1, its expression product, and the diagnostic and therapeutic applications thereof
06/24/1999WO1999031117A1 110 human secreted proteins
06/24/1999WO1999031116A1 Human dendriac and brainiac-3
06/24/1999WO1999031105A1 3-substituted adenines via2-thioxanthines
06/24/1999WO1999031104A1 Preparation of 3-substituted adenines and imidazo pyridines
06/24/1999WO1999031103A1 Preparation of 3-substituted adenines
06/24/1999WO1999031102A1 Purine derivatives having phosphodiesterase iv inhibition activity
06/24/1999WO1999031092A1 Benzamine derivatives
06/24/1999WO1999031086A1 Quinolinepiperazine and quinolinepiperidine derivatives, their preparation and their use as combined 5-ht1a, 5-ht1b and 5-ht1d receptor antagonists
06/24/1999WO1999031077A1 Arylpiperazines having activity at the serotonin 1a receptor
06/24/1999WO1999031075A1 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999WO1999031074A2 ((cyclo)alkyl substituted)-.gamma.-aminobutyric acid derivatives (=gaba analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999WO1999031068A1 Substituted isoquinoline derivatives and their use as anticonvulsants
06/24/1999WO1999031059A1 Potassium channel openers
06/24/1999WO1999031058A1 Novel heterocyclic compounds
06/24/1999WO1999031057A1 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999WO1999031051A1 1-(adamantyl)amidines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
06/24/1999WO1999031049A1 Neuroprotective agents
06/24/1999WO1999031045A1 Phenylaminoalkylcarboxylic acid derivatives and medicinal compositions containing the same
06/24/1999WO1999030741A2 Agent for gene therapy of tumor, neurodegenerative, cardiovascular and autoimmune diseases
06/24/1999WO1999030738A2 Diagnostics and therapeutics for transmissible spongiform encephalopathy and methods for the manufacture of non-infective blood products and tissue derived products