Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
06/2003
06/05/2003CA2468154A1 Methods for regulating levels of zinc, cadmium and calcium in humans and for diagnosing, or screening for the risk of developing, diseases associated with abnormal levels of cadmium, zinc and calcium in body fluids and tissues
06/05/2003CA2468131A1 Disruption of the prostaglandin e synthase 2 gene
06/05/2003CA2468071A1 Triazolo[4,3-a]pyrido[2,3-d]pyrimidin-5-one derivatives, compositions containing same, preparation method and use thereof
06/05/2003CA2468020A1 Osteopontin-related compositions and methods
06/05/2003CA2468015A1 2-aminoquinoline compounds
06/05/2003CA2468010A1 Benzazepine derivatives and their use as 5-ht ligands
06/05/2003CA2467892A1 Methods and compositions for derepression of iap-inhibited caspase
06/05/2003CA2467870A1 Substituted aryl 1,4-pyrazine derivatives
06/05/2003CA2467825A1 Benzothiazole derivatives
06/05/2003CA2467664A1 Methods of making and using theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate and theaflavin 3,3'-digallate and mixtures thereof
06/05/2003CA2467647A1 Therapeutic use of antibodies and fragments thereof binding primate ifn-gamma
06/05/2003CA2467565A1 Aromatic sulfone hydroxamic acids and their use as protease inhibitors
06/05/2003CA2466931A1 Antagonist anti-cd40 monoclonal antibody therapy for multiple sclerosis treatment
06/05/2003CA2466870A1 Methods for treating autoimmune disorders, and reagents related thereto
06/05/2003CA2466845A1 Manipulation of cytokine levels using cd83 gene products
06/05/2003CA2466478A1 Gene therapy agents for neurodegenerative diseases
06/05/2003CA2463592A1 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses
06/05/2003CA2435758A1 Polynucleotide therapy_against autoantigens for treating insulin dependent diabetes mellitus
06/04/2003EP1316611A1 L-methionine gamma-lyase with modified function
06/04/2003EP1316549A1 1-benzyl-4- (5,6-dimethoxy-2-fluoro-1-indanon)-2-yl] methylpiperidine
06/04/2003EP1316313A2 Composition for the treatment of ischemic stroke containing zonampanel and a tissue plasminogen activator
06/04/2003EP1316309A1 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
06/04/2003EP1316308A1 Transdermal therapeutic device with capsaicin and capsaicin analogs
06/04/2003EP1316203A2 Combination for treating psychoses, comprising an antipsychotic and a muscarinic agonist
06/04/2003EP1315965A2 Methods and compositions for in vitro targeting
06/04/2003EP1315840A2 Biopanning and rapid analysis of selective interactive ligands (brasil)
06/04/2003EP1315835A2 Directed differentiation of embryonic cells
06/04/2003EP1315830A2 Compositions and methods for targeting peptides in humans in vivo
06/04/2003EP1315813A2 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
06/04/2003EP1315812A2 Modified polypeptides stabilized in a desired conformation and methods for producing same
06/04/2003EP1315800A2 Human proteases
06/04/2003EP1315758A2 Methods and reagents for protease inhibition
06/04/2003EP1315753A2 Isolated human ion channel proteins, nucleic acid molecules encoding them, and uses thereof
06/04/2003EP1315735A1 Phosphate derivatives as immunoregulatory agents
06/04/2003EP1315731A1 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)one derivatives
06/04/2003EP1315730A1 1-(alkyl), 1-[(heteroaryl)alkyl] and 1-[(aryl)alkyl]-7-pyridinyl-imidazo(1,2-a)pyrimidin-5(1h)-one derivatives
06/04/2003EP1315727A2 7-oxo pyridopyrimidines
06/04/2003EP1315726A1 7- oxo pyridopyrimidines as inhibitors of cellular proliferation
06/04/2003EP1315723A1 The hydrochloride salt of 5[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
06/04/2003EP1315714A2 Quinazoline derivatives as alpha-1 adrenergic antagonists
06/04/2003EP1315710A1 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
06/04/2003EP1315703A1 Aryl substituted tetrahydroindazoles and their use as ligands for the gaba-a receptor
06/04/2003EP1315701A1 Process for the racemisation of 1-benzyl-4-(4-fluorophenyl)-3-hydroxymethyl-1,2,3,6-tetrahydropyridine to be used as intermediate in the synthesis of paroxetine
06/04/2003EP1315700A2 Substituted 4-phenyl-1-(1-phenyl-cyclohexyl)-1,2,3,6-tetrahydropyridine
06/04/2003EP1315516A2 Modulation of beta-amyloid levels by beta-secretase bace2
06/04/2003EP1315515A2 Method for treating schizophrenia and related psychoses, and the use of erythropoietin or erythropoietin derivatives for treating schizophrenic disorders and related psychoses
06/04/2003EP1315514A2 Methods and compositions for producing a neurosalutary effect in a subject
06/04/2003EP1315512A2 Adenoviral targeting and manipulation of immune system response using targeting peptides
06/04/2003EP1315506A2 Phospholipid derivatives of valproic acid and mixtures thereof
06/04/2003EP1315505A2 Pharmaceutical compositions for headache, migraine, nausea and emesis
06/04/2003EP1315504A1 1alpha-hydroxy-2-methylene-19-nor-homopregnacalciferol and its therapeutic applications
06/04/2003EP1315502A1 Method for treating erectile dysfunction and increasing libido in men
06/04/2003EP1315495A2 Use of threo-methylphenidate compounds to enhance memory
06/04/2003EP1315494A1 Agent for modulating excitatory synaptic transmission comprising a compound having alpha-7 nicotinic acetylcholine receptor activation property
06/04/2003EP1315493A1 2-3-disubstituted quinuclidines as modulators of monoamine transporters and therapeutic and diagnostic methods based thereon
06/04/2003EP1315480A2 "slow release" pharmaceutical compositions comprising lithium carbonate
06/04/2003EP1315417A2 Mutant non-human mammal for expressing the alpha6 acetylcholine nicotinic receptor subunit and use for screening substances capable of interacting with said receptor
06/04/2003EP1252150B1 Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
06/04/2003EP1226120B1 Benz[f]indoles for use in the treatment of 5ht receptor related disorders
06/04/2003EP1206248B1 Controlled-release sedative-hypnotic compositions and methods related thereto
06/04/2003EP1140945B1 Fused 1,2,4-thiadiazine derivatives, their preparation and use
06/04/2003EP1075476B1 Novel benzimidazoles and benzoxazoles
06/04/2003EP1038863B1 Substituted dimeric compounds, process for their preparation and pharmaceutical compositions thereof
06/04/2003EP1027363B1 Adenosine a1-receptor agonists
06/04/2003EP0975648B1 Morphine derivatives
06/04/2003EP0964849B1 Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
06/04/2003EP0944616B1 Bicyclic aryl carboxamides and their therapeutic use
06/04/2003EP0938496B1 Heptapeptide oxytocin analogues
06/04/2003EP0920869B1 Stable external preparations containing acetylsalicylic acid
06/04/2003EP0901487B1 2,3,6 trisubstituted-4(3h)-quinazolinones
06/04/2003EP0775135B1 N-substituted 3-azabicyclo (3.2.0)heptane derivatives useful as neuroleptics
06/04/2003EP0775118B1 Benzimidazole derivatives having dopaminergic activity
06/04/2003EP0689438B1 Pharmaceutical compositions for intranasal administration of apomorphine
06/04/2003EP0665752B1 Pharmaceutical compositions containing 3-beta-hydroxylated natural steroid derivatives, and use thereof
06/04/2003EP0656007B1 Delta opioid receptor genes
06/04/2003EP0626848B1 The use of 4-aminopyridine in the treatment of pain and spasticity resulting from spinal cord injury
06/04/2003EP0606366B1 Substituted phenserines and phenylcarbamates of (-)-eseroline, (-)-n1-noreseroline, and (-)-n1-benzylnoreseroline; as specific inhibitors of acetylcholinesterase
06/04/2003CN1422280A Novel collagen-like protein CLAC, Precursor thereof and genes encoding the same
06/04/2003CN1422273A 1,5-disubstituted-3,4-dihydro-1H-pyrimido [4,5-D] pyrimidi-2-one compounds and their use in treating CSBP/P38 kinase mediated diseases
06/04/2003CN1422270A Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines
06/04/2003CN1422269A 1H-imidazopyridine derivatives
06/04/2003CN1422266A Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
06/04/2003CN1422263A Estrogen agonist/antagonist metabolites
06/04/2003CN1422262A 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
06/04/2003CN1422260A 2-guanidino-4-arylchinazolines as NHE-3 inhibitors
06/04/2003CN1422257A Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
06/04/2003CN1422255A Heterocycle derivatives and drugs
06/04/2003CN1422254A Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof
06/04/2003CN1422253A Carbamate caspase inhibitors and uses thereof
06/04/2003CN1422246A Malonamic acids and derivatives thereof as thyroid receptor ligands
06/04/2003CN1422244A Process for producing amine derivatives
06/04/2003CN1422159A Remedies
06/04/2003CN1421453A Structure and use of acanthus illicifolius glycoside B as one fatty alcohol glycoside compound
06/04/2003CN1421236A Externally applied medicated wine for treating ischias and its making process
06/04/2003CN1110558C Novel growth/differentiation factor of the TGF-ÔÇÿbetaÔÇÖfamily
06/04/2003CN1110499C Spiro-quinuclidine derivatives, their preparation and use
06/04/2003CN1110498C Triazolo-pyridzine derivatives as ligands for GABA receptors
06/04/2003CN1110497C Di-or triaza-spiral [4,5] decane derivative
06/04/2003CN1110496C Tetrahydro Gamma-carbolines compound
06/04/2003CN1110484C 2-(cary lphenyl) amino-imidazoline derivatives